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Items: 45


Automated localization and quality control of the aorta in cine CMR can significantly accelerate processing of the UK Biobank population data.

Biasiolli L, Hann E, Lukaschuk E, Carapella V, Paiva JM, Aung N, Rayner JJ, Werys K, Fung K, Puchta H, Sanghvi MM, Moon NO, Thomson RJ, Thomas KE, Robson MD, Grau V, Petersen SE, Neubauer S, Piechnik SK.

PLoS One. 2019 Feb 14;14(2):e0212272. doi: 10.1371/journal.pone.0212272. eCollection 2019.


Physical activity and left ventricular trabeculation in the UK Biobank community-based cohort study.

Woodbridge SP, Aung N, Paiva JM, Sanghvi MM, Zemrak F, Fung K, Petersen SE.

Heart. 2019 Feb 5. pii: heartjnl-2018-314155. doi: 10.1136/heartjnl-2018-314155. [Epub ahead of print]


Independent Left Ventricular Morphometric Atlases Show Consistent Relationships with Cardiovascular Risk Factors: A UK Biobank Study.

Gilbert K, Bai W, Mauger C, Medrano-Gracia P, Suinesiaputra A, Lee AM, Sanghvi MM, Aung N, Piechnik SK, Neubauer S, Petersen SE, Rueckert D, Young AA.

Sci Rep. 2019 Feb 4;9(1):1130. doi: 10.1038/s41598-018-37916-6.


Association Between Ambient Air Pollution and Cardiac Morpho-Functional Phenotypes: Insights From the UK Biobank Population Imaging Study.

Aung N, Sanghvi MM, Zemrak F, Lee AM, Cooper JA, Paiva JM, Thomson RJ, Fung K, Khanji MY, Lukaschuk E, Carapella V, Kim YJ, Munroe PB, Piechnik SK, Neubauer S, Petersen SE.

Circulation. 2018 Nov 13;138(20):2175-2186. doi: 10.1161/CIRCULATIONAHA.118.034856. Epub 2018 Aug 2.


Persistent local demucosalization after endoscopic sinus surgery: A report of 3 cases.

Massey CJ, Sanghvi MM, Troost TR, Anand VK, Singh A.

Ear Nose Throat J. 2018 Oct-Nov;97(10-11):354-361.


Bioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and Humans.

Podoll T, Pearson PG, Evarts J, Ingallinera T, Bibikova E, Sun H, Gohdes M, Cardinal K, Sanghvi M, Slatter JG.

Drug Metab Dispos. 2019 Feb;47(2):145-154. doi: 10.1124/dmd.118.084459. Epub 2018 Nov 15.


Automated cardiovascular magnetic resonance image analysis with fully convolutional networks.

Bai W, Sinclair M, Tarroni G, Oktay O, Rajchl M, Vaillant G, Lee AM, Aung N, Lukaschuk E, Sanghvi MM, Zemrak F, Fung K, Paiva JM, Carapella V, Kim YJ, Suzuki H, Kainz B, Matthews PM, Petersen SE, Piechnik SK, Neubauer S, Glocker B, Rueckert D.

J Cardiovasc Magn Reson. 2018 Sep 14;20(1):65. doi: 10.1186/s12968-018-0471-x.


Cardiovascular magnetic resonance imaging for amyloidosis: The state-of-the-art.

Tang CX, Petersen SE, Sanghvi MM, Lu GM, Zhang LJ.

Trends Cardiovasc Med. 2019 Feb;29(2):83-94. doi: 10.1016/j.tcm.2018.06.011. Epub 2018 Jun 28. Review.


Variation in lung function and alterations in cardiac structure and function-Analysis of the UK Biobank cardiovascular magnetic resonance imaging substudy.

Thomson RJ, Aung N, Sanghvi MM, Paiva JM, Lee AM, Zemrak F, Fung K, Pfeffer PE, Mackay AJ, McKeever TM, Lukaschuk E, Carapella V, Kim YJ, Bolton CE, Piechnik SK, Neubauer S, Petersen SE.

PLoS One. 2018 Mar 20;13(3):e0194434. doi: 10.1371/journal.pone.0194434. eCollection 2018.


Prospective association between handgrip strength and cardiac structure and function in UK adults.

Beyer SE, Sanghvi MM, Aung N, Hosking A, Cooper JA, Paiva JM, Lee AM, Fung K, Lukaschuk E, Carapella V, Mittleman MA, Brage S, Piechnik SK, Neubauer S, Petersen SE.

PLoS One. 2018 Mar 14;13(3):e0193124. doi: 10.1371/journal.pone.0193124. eCollection 2018.


The impact of menopausal hormone therapy (MHT) on cardiac structure and function: Insights from the UK Biobank imaging enhancement study.

Sanghvi MM, Aung N, Cooper JA, Paiva JM, Lee AM, Zemrak F, Fung K, Thomson RJ, Lukaschuk E, Carapella V, Kim YJ, Harvey NC, Piechnik SK, Neubauer S, Petersen SE.

PLoS One. 2018 Mar 8;13(3):e0194015. doi: 10.1371/journal.pone.0194015. eCollection 2018.


Correction to: Determination of the absolute oral bioavailability of niraparib by simultaneous administration of a 14C-microtracer and therapeutic dose in cancer patients.

van Andel L, Rosing H, Zhang Z, Hughes L, Kansra V, Sanghvi M, Tibben MM, Gebretensae A, Schellens JHM, Beijnen JH.

Cancer Chemother Pharmacol. 2018 Jan;81(1):47. doi: 10.1007/s00280-017-3474-7.


Determination of the absolute oral bioavailability of niraparib by simultaneous administration of a 14C-microtracer and therapeutic dose in cancer patients.

van Andel L, Rosing H, Zhang Z, Hughes L, Kansra V, Sanghvi M, Tibben MM, Gebretensae A, Schellens JHM, Beijnen JH.

Cancer Chemother Pharmacol. 2018 Jan;81(1):39-46. doi: 10.1007/s00280-017-3455-x. Epub 2017 Oct 17. Erratum in: Cancer Chemother Pharmacol. 2017 Nov 27;:.


The impact of cardiovascular risk factors on cardiac structure and function: Insights from the UK Biobank imaging enhancement study.

Petersen SE, Sanghvi MM, Aung N, Cooper JA, Paiva JM, Zemrak F, Fung K, Lukaschuk E, Lee AM, Carapella V, Kim YJ, Piechnik SK, Neubauer S.

PLoS One. 2017 Oct 3;12(10):e0185114. doi: 10.1371/journal.pone.0185114. eCollection 2017.


Fully-automated left ventricular mass and volume MRI analysis in the UK Biobank population cohort: evaluation of initial results.

Suinesiaputra A, Sanghvi MM, Aung N, Paiva JM, Zemrak F, Fung K, Lukaschuk E, Lee AM, Carapella V, Kim YJ, Francis J, Piechnik SK, Neubauer S, Greiser A, Jolly MP, Hayes C, Young AA, Petersen SE.

Int J Cardiovasc Imaging. 2018 Feb;34(2):281-291. doi: 10.1007/s10554-017-1225-9. Epub 2017 Aug 23.


Reference ranges for cardiac structure and function using cardiovascular magnetic resonance (CMR) in Caucasians from the UK Biobank population cohort.

Petersen SE, Aung N, Sanghvi MM, Zemrak F, Fung K, Paiva JM, Francis JM, Khanji MY, Lukaschuk E, Lee AM, Carapella V, Kim YJ, Leeson P, Piechnik SK, Neubauer S.

J Cardiovasc Magn Reson. 2017 Feb 3;19(1):18. doi: 10.1186/s12968-017-0327-9.


Randomized Pharmacokinetic Crossover Study Comparing 2 Curcumin Preparations in Plasma and Rectal Tissue of Healthy Human Volunteers.

Asher GN, Xie Y, Moaddel R, Sanghvi M, Dossou KS, Kashuba AD, Sandler RS, Hawke RL.

J Clin Pharmacol. 2017 Feb;57(2):185-193. doi: 10.1002/jcph.806. Epub 2016 Sep 6.


Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet.

Bernier M, Wahl D, Ali A, Allard J, Faulkner S, Wnorowski A, Sanghvi M, Moaddel R, Alfaras I, Mattison JA, Tarantini S, Tucsek Z, Ungvari Z, Csiszar A, Pearson KJ, de Cabo R.

Aging (Albany NY). 2016 May;8(5):899-916. doi: 10.18632/aging.100942.


Subchronic administration of (R,S)-ketamine induces ketamine ring hydroxylation in Wistar rats.

Moaddel R, Sanghvi M, Ramamoorthy A, Jozwiak K, Singh N, Green C, O'Loughlin K, Torjman M, Wainer IW.

J Pharm Biomed Anal. 2016 Aug 5;127:3-8. doi: 10.1016/j.jpba.2016.03.030. Epub 2016 Mar 14.


Delayed diagnosis of anaphylaxis secondary to ondansetron: A case report.

Goyal P, Paramesh K, Puranik S, Proctor M, Sanghvi M.

Eur J Anaesthesiol. 2016 Feb;33(2):146-7. doi: 10.1097/EJA.0000000000000372. No abstract available.


The distribution and clearance of (2S,6S)-hydroxynorketamine, an active ketamine metabolite, in Wistar rats.

Moaddel R, Sanghvi M, Dossou KS, Ramamoorthy A, Green C, Bupp J, Swezey R, O'Loughlin K, Wainer IW.

Pharmacol Res Perspect. 2015 Aug;3(4):e00157. doi: 10.1002/prp2.157. Epub 2015 Jun 22.


(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.

Paul RK, Singh NS, Khadeer M, Moaddel R, Sanghvi M, Green CE, O'Loughlin K, Torjman MC, Bernier M, Wainer IW.

Anesthesiology. 2014 Jul;121(1):149-59. doi: 10.1097/ALN.0000000000000285.


Variably severe systemic allergic reactions after consuming foods with unlabelled lupin flour: a case series.

Bansal AS, Sanghvi MM, Bansal RA, Hayman GR.

J Med Case Rep. 2014 Feb 16;8:55. doi: 10.1186/1752-1947-8-55.


Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet.

Jimenez-Gomez Y, Mattison JA, Pearson KJ, Martin-Montalvo A, Palacios HH, Sossong AM, Ward TM, Younts CM, Lewis K, Allard JS, Longo DL, Belman JP, Malagon MM, Navas P, Sanghvi M, Moaddel R, Tilmont EM, Herbert RL, Morrell CH, Egan JM, Baur JA, Ferrucci L, Bogan JS, Bernier M, de Cabo R.

Cell Metab. 2013 Oct 1;18(4):533-45. doi: 10.1016/j.cmet.2013.09.004.


Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells.

Lee-Chang C, Bodogai M, Martin-Montalvo A, Wejksza K, Sanghvi M, Moaddel R, de Cabo R, Biragyn A.

J Immunol. 2013 Oct 15;191(8):4141-51. doi: 10.4049/jimmunol.1300606. Epub 2013 Sep 16.


Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet.

Fiori JL, Shin YK, Kim W, Krzysik-Walker SM, González-Mariscal I, Carlson OD, Sanghvi M, Moaddel R, Farhang K, Gadkaree SK, Doyle ME, Pearson KJ, Mattison JA, de Cabo R, Egan JM.

Diabetes. 2013 Oct;62(10):3500-13. doi: 10.2337/db13-0266. Epub 2013 Jul 24.


Development and validation of a sensitive LC-MS/MS method for the determination of fenoterol in human plasma and urine samples.

Sanghvi M, Ramamoorthy A, Strait J, Wainer IW, Moaddel R.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Aug 15;933:37-43. doi: 10.1016/j.jchromb.2013.06.020. Epub 2013 Jun 26.


Neglected tropical diseases as a cause of chronic liver disease: the case of Schistosomiasis and Hepatitis C Co-infections in Egypt.

Sanghvi MM, Hotez PJ, Fenwick A.

Liver Int. 2013 Feb;33(2):165-8. doi: 10.1111/liv.12052. No abstract available.


Alcohol-induced one-carbon metabolism impairment promotes dysfunction of DNA base excision repair in adult brain.

Fowler AK, Hewetson A, Agrawal RG, Dagda M, Dagda R, Moaddel R, Balbo S, Sanghvi M, Chen Y, Hogue RJ, Bergeson SE, Henderson GI, Kruman II.

J Biol Chem. 2012 Dec 21;287(52):43533-42. doi: 10.1074/jbc.M112.401497. Epub 2012 Nov 1.


Spontaneous trigeminal allodynia in rats: a model of primary headache.

Oshinsky ML, Sanghvi MM, Maxwell CR, Gonzalez D, Spangenberg RJ, Cooper M, Silberstein SD.

Headache. 2012 Oct;52(9):1336-49. doi: 10.1111/j.1526-4610.2012.02247.x. Epub 2012 Sep 10.


Stereoselective and regiospecific hydroxylation of ketamine and norketamine.

Desta Z, Moaddel R, Ogburn ET, Xu C, Ramamoorthy A, Venkata SL, Sanghvi M, Goldberg ME, Torjman MC, Wainer IW.

Xenobiotica. 2012 Nov;42(11):1076-87. doi: 10.3109/00498254.2012.685777. Epub 2012 May 21.


Combined mutational analysis of KRAS, NRAS and BRAF genes in Indian patients with colorectal carcinoma.

Bagadi SB, Sanghvi M, Nair SB, Das BR.

Int J Biol Markers. 2012 Jan-Mar;27(1):27-33. doi: 10.5301/JBM.2012.9108.


Breast cancer resistance protein (BCRP/ABCG2) localises to the nucleus in glioblastoma multiforme cells.

Bhatia P, Bernier M, Sanghvi M, Moaddel R, Schwarting R, Ramamoorthy A, Wainer IW.

Xenobiotica. 2012 Aug;42(8):748-55. doi: 10.3109/00498254.2012.662726. Epub 2012 Mar 8.


The development and characterization of protein-based stationary phases for studying drug-protein and protein-protein interactions.

Sanghvi M, Moaddel R, Wainer IW.

J Chromatogr A. 2011 Dec 9;1218(49):8791-8. doi: 10.1016/j.chroma.2011.05.067. Epub 2011 May 27. Review.


The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor α protein.

Fiori JL, Sanghvi M, O'Connell MP, Krzysik-Walker SM, Moaddel R, Bernier M.

Br J Pharmacol. 2011 Oct;164(3):1026-40. doi: 10.1111/j.1476-5381.2011.01384.x.


Synthesis and characterization of liquid chromatographic columns containing the immobilized ligand binding domain of the estrogen related receptor alpha and estrogen related receptor gamma.

Sanghvi M, Moaddel R, Frazier C, Wainer IW.

J Pharm Biomed Anal. 2010 Nov 2;53(3):777-80. doi: 10.1016/j.jpba.2010.05.016. Epub 2010 Jun 9.


Hydrophobic photolabeling studies identify the lipid-protein interface of the 5-HT3A receptor.

Sanghvi M, Hamouda AK, Davis MI, Morton RA, Srivastava S, Pandhare A, Duddempudi PK, Machu TK, Lovinger DM, Cohen JB, Blanton MP.

Biochemistry. 2009 Oct 6;48(39):9278-86. doi: 10.1021/bi901208j.


[(3)H]Epibatidine photolabels non-equivalent amino acids in the agonist binding site of Torpedo and alpha4beta2 nicotinic acetylcholine receptors.

Srivastava S, Hamouda AK, Pandhare A, Duddempudi PK, Sanghvi M, Cohen JB, Blanton MP.

J Biol Chem. 2009 Sep 11;284(37):24939-47. doi: 10.1074/jbc.M109.019083. Epub 2009 Jul 20.


Synthesis and characterization of a cellular membrane affinity chromatography column containing histamine 1 and P2Y(1) receptors: a multiple G-protein coupled receptor column.

Moaddel R, Musyimi HK, Sanghvi M, Bashore C, Frazier CR, Khadeer M, Bhatia P, Wainer IW.

J Pharm Biomed Anal. 2010 Jul 8;52(3):416-9. doi: 10.1016/j.jpba.2009.06.035. Epub 2009 Jun 26.


Photoaffinity labeling the agonist binding domain of alpha4beta4 and alpha4beta2 neuronal nicotinic acetylcholine receptors with [(125)I]epibatidine and 5[(125)I]A-85380.

Hamouda AK, Jin X, Sanghvi M, Srivastava S, Pandhare A, Duddempudi PK, Steinbach JH, Blanton MP.

Biochim Biophys Acta. 2009 Sep;1788(9):1987-95. doi: 10.1016/j.bbamem.2009.06.012. Epub 2009 Jun 21.


Identifying the binding site(s) for antidepressants on the Torpedo nicotinic acetylcholine receptor: [3H]2-azidoimipramine photolabeling and molecular dynamics studies.

Sanghvi M, Hamouda AK, Jozwiak K, Blanton MP, Trudell JR, Arias HR.

Biochim Biophys Acta. 2008 Dec;1778(12):2690-9. doi: 10.1016/j.bbamem.2008.08.019. Epub 2008 Sep 10.


Centrifugation enhances integrin-mediated transduction of dendritic cells by conventional and RGD-modified adenoviral vectors.

Harui A, Roth MD, Sanghvi M, Vira D, Mizuguchi H, Basak SK.

J Immunol Methods. 2006 May 30;312(1-2):94-104. Epub 2006 Mar 31.


Adenoviral-encoded antigens are presented efficiently by a subset of dendritic cells expressing high levels of alpha(v)beta3 integrins.

Harui A, Roth MD, Vira D, Sanghvi M, Mizuguchi H, Basak SK.

J Leukoc Biol. 2006 Jun;79(6):1271-8. Epub 2006 Mar 30.


Assessing the lipid requirements of the Torpedo californica nicotinic acetylcholine receptor.

Hamouda AK, Sanghvi M, Sauls D, Machu TK, Blanton MP.

Biochemistry. 2006 Apr 4;45(13):4327-37.

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