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Items: 22


Adipose tissue dysfunction as a central mechanism leading to dysmetabolic obesity triggered by chronic exposure to p,p'-DDE.

Pestana D, Teixeira D, Meireles M, Marques C, Norberto S, Sá C, Fernandes VC, Correia-Sá L, Faria A, Guardão L, Guimarães JT, Cooper WN, Sandovici I, Domingues VF, Delerue-Matos C, Monteiro R, Constância M, Calhau C.

Sci Rep. 2017 Jun 1;7(1):2738. doi: 10.1038/s41598-017-02885-9.


Placental phenotype and the insulin-like growth factors: resource allocation to fetal growth.

Sferruzzi-Perri AN, Sandovici I, Constancia M, Fowden AL.

J Physiol. 2017 Aug 1;595(15):5057-5093. doi: 10.1113/JP273330. Epub 2017 May 23. Review.


Ageing is associated with molecular signatures of inflammation and type 2 diabetes in rat pancreatic islets.

Sandovici I, Hammerle CM, Cooper WN, Smith NH, Tarry-Adkins JL, Dunmore BJ, Bauer J, Andrews SR, Yeo GS, Ozanne SE, Constância M.

Diabetologia. 2016 Mar;59(3):502-11. doi: 10.1007/s00125-015-3837-8. Epub 2015 Dec 23.


Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis.

Ferrón SR, Radford EJ, Domingo-Muelas A, Kleine I, Ramme A, Gray D, Sandovici I, Constancia M, Ward A, Menheniott TR, Ferguson-Smith AC.

Nat Commun. 2015 Sep 15;6:8265. doi: 10.1038/ncomms9265.


Extracardiac control of embryonic cardiomyocyte proliferation and ventricular wall expansion.

Shen H, Cavallero S, Estrada KD, Sandovici I, Kumar SR, Makita T, Lien CL, Constancia M, Sucov HM.

Cardiovasc Res. 2015 Mar 1;105(3):271-8. doi: 10.1093/cvr/cvu269. Epub 2015 Jan 5.


Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes.

Sandovici I, Hammerle CM, Ozanne SE, Constância M.

Cell Mol Life Sci. 2013 May;70(9):1575-95. doi: 10.1007/s00018-013-1297-1. Epub 2013 Mar 6. Review.


Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes.

Haley VL, Barnes DJ, Sandovici I, Constancia M, Graham CF, Pezzella F, Bühnemann C, Carter EJ, Hassan AB.

EMBO Mol Med. 2012 Aug;4(8):705-18. doi: 10.1002/emmm.201101105. Epub 2012 Jun 6.


Placental adaptations to the maternal-fetal environment: implications for fetal growth and developmental programming.

Sandovici I, Hoelle K, Angiolini E, Constância M.

Reprod Biomed Online. 2012 Jul;25(1):68-89. doi: 10.1016/j.rbmo.2012.03.017. Epub 2012 Apr 5. Review.


Maternal diet, aging and diabetes meet at a chromatin loop.

Ozanne SE, Sandovici I, Constância M.

Aging (Albany NY). 2011 May;3(5):548-54.


Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets.

Sandovici I, Smith NH, Nitert MD, Ackers-Johnson M, Uribe-Lewis S, Ito Y, Jones RH, Marquez VE, Cairns W, Tadayyon M, O'Neill LP, Murrell A, Ling C, Constância M, Ozanne SE.

Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5449-54. doi: 10.1073/pnas.1019007108. Epub 2011 Mar 8.


Developmental adaptations to increased fetal nutrient demand in mouse genetic models of Igf2-mediated overgrowth.

Angiolini E, Coan PM, Sandovici I, Iwajomo OH, Peck G, Burton GJ, Sibley CP, Reik W, Fowden AL, Constância M.

FASEB J. 2011 May;25(5):1737-45. doi: 10.1096/fj.10-175273. Epub 2011 Jan 31.


PRDM9 sticks its zinc fingers into recombination hotspots and between species.

Sandovici I, Sapienza C.

F1000 Biol Rep. 2010 May 24;2. pii: 37. doi: 10.3410/B2-37.


Adaptations in placental nutrient transfer capacity to meet fetal growth demands depend on placental size in mice.

Coan PM, Angiolini E, Sandovici I, Burton GJ, Constância M, Fowden AL.

J Physiol. 2008 Sep 15;586(18):4567-76. doi: 10.1113/jphysiol.2008.156133. Epub 2008 Jul 24.


Human imprinted chromosomal regions are historical hot-spots of recombination.

Sandovici I, Kassovska-Bratinova S, Vaughan JE, Stewart R, Leppert M, Sapienza C.

PLoS Genet. 2006 Jul;2(7):e101. Epub 2006 May 22.


Regulation of placental efficiency for nutrient transport by imprinted genes.

Angiolini E, Fowden A, Coan P, Sandovici I, Smith P, Dean W, Burton G, Tycko B, Reik W, Sibley C, Constância M.

Placenta. 2006 Apr;27 Suppl A:S98-102. Epub 2006 Feb 28. Review.


Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems.

Constância M, Angiolini E, Sandovici I, Smith P, Smith R, Kelsey G, Dean W, Ferguson-Smith A, Sibley CP, Reik W, Fowden A.

Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19219-24. Epub 2005 Dec 19.


Interindividual variability and parent of origin DNA methylation differences at specific human Alu elements.

Sandovici I, Kassovska-Bratinova S, Loredo-Osti JC, Leppert M, Suarez A, Stewart R, Bautista FD, Schiraldi M, Sapienza C.

Hum Mol Genet. 2005 Aug 1;14(15):2135-43. Epub 2005 Jun 22.


A longitudinal study of X-inactivation ratio in human females.

Sandovici I, Naumova AK, Leppert M, Linares Y, Sapienza C.

Hum Genet. 2004 Oct;115(5):387-92. Epub 2004 Aug 28.


Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions.

Sandovici I, Leppert M, Hawk PR, Suarez A, Linares Y, Sapienza C.

Hum Mol Genet. 2003 Jul 1;12(13):1569-78. Erratum in: Hum Mol Genet. 2004 Apr 1;13(7):781.


[DNA repair pathways and their involvement in human diseases].

Sandovici I, Buhuşi MC, Stoica O, Covic M.

Rev Med Chir Soc Med Nat Iasi. 2002 Apr-Jun;107(2):247-57. Review. Romanian.


[Genetic susceptibility to cancer].

Stoica O, Sandovici I, Covic M.

Rev Med Chir Soc Med Nat Iasi. 2000 Apr-Jun;104(2):21-30. Romanian.


[Chaperone proteins--essential proteins for cellular activity].

Sandovici I, Bostaca I.

Rev Med Chir Soc Med Nat Iasi. 1999 Jul-Dec;103(3-4):35-43. Review. Romanian.


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