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Items: 30

1.

SUPT4H1 Depletion Leads to a Global Reduction in RNA.

Naguib A, Sandmann T, Yi F, Watts RJ, Lewcock JW, Dowdle WE.

Cell Rep. 2019 Jan 2;26(1):45-53.e4. doi: 10.1016/j.celrep.2018.12.004.

2.

Obinutuzumab plus CHOP is effective and has a tolerable safety profile in previously untreated, advanced diffuse large B-cell lymphoma: the phase II GATHER study.

Sharman JP, Forero-Torres A, Costa LJ, Flinn IW, Inhorn L, Kelly K, Bessudo A, Fayad LE, Kaminski MS, Evens AM, Flowers CR, Sahin D, Mundt KE, Sandmann T, Fingerle-Rowson G, Vignal C, Mobasher M, Zelenetz AD.

Leuk Lymphoma. 2019 Apr;60(4):894-903. doi: 10.1080/10428194.2018.1515940. Epub 2018 Oct 2.

PMID:
30277102
3.

Radiologic progression of glioblastoma under therapy-an exploratory analysis of AVAglio.

Nowosielski M, Ellingson BM, Chinot OL, Garcia J, Revil C, Radbruch A, Nishikawa R, Mason WP, Henriksson R, Saran F, Kickingereder P, Platten M, Sandmann T, Abrey LE, Cloughesy TF, Bendszus M, Wick W.

Neuro Oncol. 2018 Mar 27;20(4):557-566. doi: 10.1093/neuonc/nox162.

4.

High-Throughput and Sensitive Quantification of Circulating Tumor DNA by Microfluidic-Based Multiplex PCR and Next-Generation Sequencing.

Guan Y, Mayba O, Sandmann T, Lu S, Choi Y, Darbonne WC, Leveque V, Ryner L, Humke E, Tam NWR, Sujathasarma S, Cheung A, Bourgon R, Lackner MR, Wang Y.

J Mol Diagn. 2017 Nov;19(6):921-932. doi: 10.1016/j.jmoldx.2017.08.001. Epub 2017 Sep 1.

PMID:
28867605
5.

Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Study of Onartuzumab Plus Bevacizumab Versus Placebo Plus Bevacizumab in Patients With Recurrent Glioblastoma: Efficacy, Safety, and Hepatocyte Growth Factor and O6-Methylguanine-DNA Methyltransferase Biomarker Analyses.

Cloughesy T, Finocchiaro G, Belda-Iniesta C, Recht L, Brandes AA, Pineda E, Mikkelsen T, Chinot OL, Balana C, Macdonald DR, Westphal M, Hopkins K, Weller M, Bais C, Sandmann T, Bruey JM, Koeppen H, Liu B, Verret W, Phan SC, Shames DS.

J Clin Oncol. 2017 Jan 20;35(3):343-351. doi: 10.1200/JCO.2015.64.7685. Epub 2016 Dec 5.

PMID:
27918718
6.

Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter.

Qu X, Sandmann T, Frierson H Jr, Fu L, Fuentes E, Walter K, Okrah K, Rumpel C, Moskaluk C, Lu S, Wang Y, Bourgon R, Penuel E, Pirzkall A, Amler L, Lackner MR, Tabernero J, Hampton GM, Kabbarah O.

Oncogene. 2016 Dec 15;35(50):6403-6415. doi: 10.1038/onc.2016.170. Epub 2016 Jun 6.

7.

A genetic interaction map of cell cycle regulators.

Billmann M, Horn T, Fischer B, Sandmann T, Huber W, Boutros M.

Mol Biol Cell. 2016 Apr 15;27(8):1397-407. doi: 10.1091/mbc.E15-07-0467. Epub 2016 Feb 24.

8.

Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe.

Mattila J, Havula E, Suominen E, Teesalu M, Surakka I, Hynynen R, Kilpinen H, Väänänen J, Hovatta I, Käkelä R, Ripatti S, Sandmann T, Hietakangas V.

Cell Rep. 2015 Oct 13;13(2):350-64. doi: 10.1016/j.celrep.2015.08.081. Epub 2015 Oct 1.

9.

Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial.

Sandmann T, Bourgon R, Garcia J, Li C, Cloughesy T, Chinot OL, Wick W, Nishikawa R, Mason W, Henriksson R, Saran F, Lai A, Moore N, Kharbanda S, Peale F, Hegde P, Abrey LE, Phillips HS, Bais C.

J Clin Oncol. 2015 Sep 1;33(25):2735-44. doi: 10.1200/JCO.2015.61.5005. Epub 2015 Jun 29. Erratum in: J Clin Oncol. 2016 Sep 1;34(25):3113.

10.

Embryo development. A cysteine-clamp gene drives embryo polarity in the midge Chironomus.

Klomp J, Athy D, Kwan CW, Bloch NI, Sandmann T, Lemke S, Schmidt-Ott U.

Science. 2015 May 29;348(6238):1040-2. doi: 10.1126/science.aaa7105. Epub 2015 May 7.

11.

Development of a SPE-HPLC-MS/MS method for the determination of most prescribed pharmaceuticals and related metabolites in urban sewage samples.

Gurke R, Rossmann J, Schubert S, Sandmann T, Rößler M, Oertel R, Fauler J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 May 15;990:23-30. doi: 10.1016/j.jchromb.2015.03.008. Epub 2015 Mar 23.

PMID:
25841203
12.

A map of directional genetic interactions in a metazoan cell.

Fischer B, Sandmann T, Horn T, Billmann M, Chaudhary V, Huber W, Boutros M.

Elife. 2015 Mar 6;4. doi: 10.7554/eLife.05464.

13.

Anti-CD22 and anti-CD79B antibody drug conjugates are active in different molecular diffuse large B-cell lymphoma subtypes.

Pfeifer M, Zheng B, Erdmann T, Koeppen H, McCord R, Grau M, Staiger A, Chai A, Sandmann T, Madle H, Dörken B, Chu YW, Chen AI, Lebovic D, Salles GA, Czuczman MS, Palanca-Wessels MC, Press OW, Advani R, Morschhauser F, Cheson BD, Lenz P, Ott G, Polson AG, Mundt KE, Lenz G.

Leukemia. 2015 Jul;29(7):1578-86. doi: 10.1038/leu.2015.48. Epub 2015 Feb 24.

PMID:
25708834
14.

Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells.

Voloshanenko O, Erdmann G, Dubash TD, Augustin I, Metzig M, Moffa G, Hundsrucker C, Kerr G, Sandmann T, Anchang B, Demir K, Boehm C, Leible S, Ball CR, Glimm H, Spang R, Boutros M.

Nat Commun. 2013;4:2610. doi: 10.1038/ncomms3610.

15.

gCMAP: user-friendly connectivity mapping with R.

Sandmann T, Kummerfeld SK, Gentleman R, Bourgon R.

Bioinformatics. 2014 Jan 1;30(1):127-8. doi: 10.1093/bioinformatics/btt592. Epub 2013 Oct 15.

PMID:
24132929
16.

Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells.

Kathagen A, Schulte A, Balcke G, Phillips HS, Martens T, Matschke J, Günther HS, Soriano R, Modrusan Z, Sandmann T, Kuhl C, Tissier A, Holz M, Krawinkel LA, Glatzel M, Westphal M, Lamszus K.

Acta Neuropathol. 2013 Nov;126(5):763-80. doi: 10.1007/s00401-013-1173-y. Epub 2013 Sep 5.

PMID:
24005892
17.

Mondo/ChREBP-Mlx-regulated transcriptional network is essential for dietary sugar tolerance in Drosophila.

Havula E, Teesalu M, Hyötyläinen T, Seppälä H, Hasygar K, Auvinen P, Orešič M, Sandmann T, Hietakangas V.

PLoS Genet. 2013 Apr;9(4):e1003438. doi: 10.1371/journal.pgen.1003438. Epub 2013 Apr 4.

18.

Screens, maps & networks: from genome sequences to personalized medicine.

Sandmann T, Boutros M.

Curr Opin Genet Dev. 2012 Feb;22(1):36-44. doi: 10.1016/j.gde.2012.02.001. Epub 2012 Feb 25. Review.

19.

Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi.

Axelsson E, Sandmann T, Horn T, Boutros M, Huber W, Fischer B.

BMC Bioinformatics. 2011 Aug 17;12:342. doi: 10.1186/1471-2105-12-342.

20.

The head-regeneration transcriptome of the planarian Schmidtea mediterranea.

Sandmann T, Vogg MC, Owlarn S, Boutros M, Bartscherer K.

Genome Biol. 2011 Aug 16;12(8):R76. doi: 10.1186/gb-2011-12-8-r76.

21.

Mapping of signaling networks through synthetic genetic interaction analysis by RNAi.

Horn T, Sandmann T, Fischer B, Axelsson E, Huber W, Boutros M.

Nat Methods. 2011 Apr;8(4):341-6. doi: 10.1038/nmeth.1581. Epub 2011 Mar 6.

PMID:
21378980
22.

Combinatorial binding leads to diverse regulatory responses: Lmd is a tissue-specific modulator of Mef2 activity.

Cunha PM, Sandmann T, Gustafson EH, Ciglar L, Eichenlaub MP, Furlong EE.

PLoS Genet. 2010 Jul 1;6(7):e1001014. doi: 10.1371/journal.pgen.1001014.

23.

Design and evaluation of genome-wide libraries for RNA interference screens.

Horn T, Sandmann T, Boutros M.

Genome Biol. 2010;11(6):R61. doi: 10.1186/gb-2010-11-6-r61. Epub 2010 Jun 15.

24.

Drosophila Minus is required for cell proliferation and influences Cyclin E turnover.

Szuplewski S, Sandmann T, Hietakangas V, Cohen SM.

Genes Dev. 2009 Sep 1;23(17):1998-2003. doi: 10.1101/gad.1822409.

25.

Identification of novel Drosophila melanogaster microRNAs.

Sandmann T, Cohen SM.

PLoS One. 2007 Nov 28;2(11):e1265.

26.

Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network.

Jakobsen JS, Braun M, Astorga J, Gustafson EH, Sandmann T, Karzynski M, Carlsson P, Furlong EE.

Genes Dev. 2007 Oct 1;21(19):2448-60.

27.
28.

A core transcriptional network for early mesoderm development in Drosophila melanogaster.

Sandmann T, Girardot C, Brehme M, Tongprasit W, Stolc V, Furlong EE.

Genes Dev. 2007 Feb 15;21(4):436-49.

29.

A temporal map of transcription factor activity: mef2 directly regulates target genes at all stages of muscle development.

Sandmann T, Jensen LJ, Jakobsen JS, Karzynski MM, Eichenlaub MP, Bork P, Furlong EE.

Dev Cell. 2006 Jun;10(6):797-807.

30.

Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae.

Sandmann T, Herrmann JM, Dengjel J, Schwarz H, Spang A.

Mol Biol Cell. 2003 Aug;14(8):3097-113. Epub 2003 May 3.

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