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Items: 4

1.

Structure and function of the histone chaperone FACT - Resolving FACTual issues.

Gurova K, Chang HW, Valieva ME, Sandlesh P, Studitsky VM.

Biochim Biophys Acta Gene Regul Mech. 2018 Jul 25. pii: S1874-9399(18)30159-7. doi: 10.1016/j.bbagrm.2018.07.008. [Epub ahead of print] Review.

PMID:
30055319
2.

Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene.

Sandlesh P, Juang T, Safina A, Higgins MJ, Gurova KV.

PLoS One. 2018 Jun 28;13(6):e0199785. doi: 10.1371/journal.pone.0199785. eCollection 2018.

3.

TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells.

Leonova K, Safina A, Nesher E, Sandlesh P, Pratt R, Burkhart C, Lipchick B, Gitlin I, Frangou C, Koman I, Wang J, Kirsanov K, Yakubovskaya MG, Gudkov AV, Gurova K.

Elife. 2018 Feb 5;7. pii: e30842. doi: 10.7554/eLife.30842.

4.

Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models.

Dermawan JK, Hitomi M, Silver DJ, Wu Q, Sandlesh P, Sloan AE, Purmal AA, Gurova KV, Rich JN, Lathia JD, Stark GR, Venere M.

Cancer Res. 2016 Apr 15;76(8):2432-42. doi: 10.1158/0008-5472.CAN-15-2162. Epub 2016 Feb 26.

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