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Items: 18

1.

HDAC inhibitors as antifibrotic drugs in cardiac and pulmonary fibrosis.

Lyu X, Hu M, Peng J, Zhang X, Sanders YY.

Ther Adv Chronic Dis. 2019 Jul 18;10:2040622319862697. doi: 10.1177/2040622319862697. eCollection 2019. Review.

2.

Inhibition of Glutaminase 1 Attenuates Experimental Pulmonary Fibrosis.

Cui H, Xie N, Jiang D, Banerjee S, Ge J, Sanders YY, Liu G.

Am J Respir Cell Mol Biol. 2019 Apr 3. doi: 10.1165/rcmb.2019-0051OC. [Epub ahead of print]

PMID:
30943369
3.

BETting on Novel Treatments for Asthma: Bromodomain 4 Inhibitors.

Sanders YY, Thannickal VJ.

Am J Respir Cell Mol Biol. 2019 Jan;60(1):7-8. doi: 10.1165/rcmb.2018-0271ED. No abstract available.

PMID:
30157386
4.

Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts.

Bai L, Bernard K, Tang X, Hu M, Horowitz JC, Thannickal VJ, Sanders YY.

Am J Respir Cell Mol Biol. 2019 Jan;60(1):49-57. doi: 10.1165/rcmb.2018-0180OC.

PMID:
30130138
5.

DNA methylation regulated gene expression in organ fibrosis.

Zhang X, Hu M, Lyu X, Li C, Thannickal VJ, Sanders YY.

Biochim Biophys Acta Mol Basis Dis. 2017 Sep;1863(9):2389-2397. doi: 10.1016/j.bbadis.2017.05.010. Epub 2017 May 10. Review.

6.

Epigenetic Regulation of Caveolin-1 Gene Expression in Lung Fibroblasts.

Sanders YY, Liu H, Scruggs AM, Duncan SR, Huang SK, Thannickal VJ.

Am J Respir Cell Mol Biol. 2017 Jan;56(1):50-61. doi: 10.1165/rcmb.2016-0034OC.

7.

Novel Mechanisms for the Antifibrotic Action of Nintedanib.

Rangarajan S, Kurundkar A, Kurundkar D, Bernard K, Sanders YY, Ding Q, Antony VB, Zhang J, Zmijewski J, Thannickal VJ.

Am J Respir Cell Mol Biol. 2016 Jan;54(1):51-9. doi: 10.1165/rcmb.2014-0445OC.

8.

SMAD-independent down-regulation of caveolin-1 by TGF-β: effects on proliferation and survival of myofibroblasts.

Sanders YY, Cui Z, Le Saux CJ, Horowitz JC, Rangarajan S, Kurundkar A, Antony VB, Thannickal VJ.

PLoS One. 2015 Feb 6;10(2):e0116995. doi: 10.1371/journal.pone.0116995. eCollection 2015.

9.

Epigenetic mechanisms regulate NADPH oxidase-4 expression in cellular senescence.

Sanders YY, Liu H, Liu G, Thannickal VJ.

Free Radic Biol Med. 2015 Feb;79:197-205. doi: 10.1016/j.freeradbiomed.2014.12.008. Epub 2014 Dec 17.

PMID:
25526894
10.

Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance.

Hecker L, Logsdon NJ, Kurundkar D, Kurundkar A, Bernard K, Hock T, Meldrum E, Sanders YY, Thannickal VJ.

Sci Transl Med. 2014 Apr 9;6(231):231ra47. doi: 10.1126/scitranslmed.3008182.

11.

Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice.

Sanders YY, Hagood JS, Liu H, Zhang W, Ambalavanan N, Thannickal VJ.

Eur Respir J. 2014 May;43(5):1448-58. doi: 10.1183/09031936.00095113. Epub 2014 Mar 6.

12.

Histone deacetylase inhibition downregulates collagen 3A1 in fibrotic lung fibroblasts.

Zhang X, Liu H, Hock T, Thannickal VJ, Sanders YY.

Int J Mol Sci. 2013 Sep 27;14(10):19605-17. doi: 10.3390/ijms141019605.

13.

Histone modifications in senescence-associated resistance to apoptosis by oxidative stress.

Sanders YY, Liu H, Zhang X, Hecker L, Bernard K, Desai L, Liu G, Thannickal VJ.

Redox Biol. 2013 Jan 31;1:8-16. doi: 10.1016/j.redox.2012.11.004. eCollection 2013.

14.

Altered DNA methylation profile in idiopathic pulmonary fibrosis.

Sanders YY, Ambalavanan N, Halloran B, Zhang X, Liu H, Crossman DK, Bray M, Zhang K, Thannickal VJ, Hagood JS.

Am J Respir Crit Care Med. 2012 Sep 15;186(6):525-35. doi: 10.1164/rccm.201201-0077OC. Epub 2012 Jun 14.

15.

Participation of miR-200 in pulmonary fibrosis.

Yang S, Banerjee S, de Freitas A, Sanders YY, Ding Q, Matalon S, Thannickal VJ, Abraham E, Liu G.

Am J Pathol. 2012 Feb;180(2):484-93. doi: 10.1016/j.ajpath.2011.10.005. Epub 2011 Dec 20.

16.

Epigenetic regulation of thy-1 by histone deacetylase inhibitor in rat lung fibroblasts.

Sanders YY, Tollefsbol TO, Varisco BM, Hagood JS.

Am J Respir Cell Mol Biol. 2011 Jul;45(1):16-23. doi: 10.1165/rcmb.2010-0154OC. Epub 2010 Aug 19.

17.

Thy-1 promoter hypermethylation: a novel epigenetic pathogenic mechanism in pulmonary fibrosis.

Sanders YY, Pardo A, Selman M, Nuovo GJ, Tollefsbol TO, Siegal GP, Hagood JS.

Am J Respir Cell Mol Biol. 2008 Nov;39(5):610-8. doi: 10.1165/rcmb.2007-0322OC. Epub 2008 Jun 12.

18.

Enhanced myofibroblastic differentiation and survival in Thy-1(-) lung fibroblasts.

Sanders YY, Kumbla P, Hagood JS.

Am J Respir Cell Mol Biol. 2007 Feb;36(2):226-35. Epub 2006 Sep 7.

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