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Items: 1 to 50 of 125

1.

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial.

Al-Shahi Salman R, Minks DP, Mitra D, Rodrigues MA, Bhatnagar P, du Plessis JC, Joshi Y, Dennis MS, Murray GD, Newby DE, Sandercock PAG, Sprigg N, Stephen J, Sudlow CLM, Werring DJ, Whiteley WN, Wardlaw JM, White PM; RESTART Collaboration.

Lancet Neurol. 2019 Jul;18(7):643-652. doi: 10.1016/S1474-4422(19)30184-X. Epub 2019 May 22.

2.

The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: statistical analysis plan for a randomised controlled trial.

Al-Shahi Salman R, Murray GD, Dennis MS, Newby DE, Sandercock PAG, Sprigg N, Sudlow CLM, Werring DJ, White PM, Whiteley WN.

Trials. 2019 Mar 25;20(1):183. doi: 10.1186/s13063-019-3270-2.

3.

Effect of IV alteplase on the ischemic brain lesion at 24-48 hours after ischemic stroke.

Mair G, von Kummer R, Morris Z, von Heijne A, Bradey N, Cala L, Peeters A, Farrall AJ, Adami A, Potter G, Sandercock PAG, Lindley RI, Wardlaw JM; IST-3 Collaborative Group.

Neurology. 2018 Nov 27;91(22):e2067-e2077. doi: 10.1212/WNL.0000000000006575. Epub 2018 Oct 26.

4.

Visual Rating Scales of White Matter Hyperintensities and Atrophy: Comparison of Computed Tomography and Magnetic Resonance Imaging.

Ferguson KJ, Cvoro V, MacLullich AMJ, Shenkin SD, Sandercock PAG, Sakka E, Wardlaw JM.

J Stroke Cerebrovasc Dis. 2018 Jul;27(7):1815-1821. doi: 10.1016/j.jstrokecerebrovasdis.2018.02.028. Epub 2018 Mar 23.

5.

The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: study protocol for a randomised controlled trial.

Al-Shahi Salman R, Dennis MS, Murray GD, Innes K, Drever J, Dinsmore L, Williams C, White PM, Whiteley WN, Sandercock PAG, Sudlow CLM, Newby DE, Sprigg N, Werring DJ; RESTART collaborators.

Trials. 2018 Mar 5;19(1):162. doi: 10.1186/s13063-018-2542-6.

6.

Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: Individual-patient-data meta-analysis of randomized trials.

Hacke W, Lyden P, Emberson J, Baigent C, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis SM, Donnan GA, Grotta JC, Howard G, Kaste M, Koga M, von Kummer R, Lansberg MG, Lindley RI, Olivot JM, Parsons M, Sandercock PA, Toni D, Toyoda K, Wahlgren N, Wardlaw JM, Whiteley WN, Del Zoppo G, Lees KR; Stroke Thrombolysis Trialists’ Collaborators Group.

Int J Stroke. 2018 Feb;13(2):175-189. doi: 10.1177/1747493017744464. Epub 2017 Nov 24. Erratum in: Int J Stroke. 2018 Feb;13(2):NP3.

PMID:
29171359
7.

Controversies in Thrombolysis.

Sandercock PAG, Ricci S.

Curr Neurol Neurosci Rep. 2017 Aug;17(8):60. doi: 10.1007/s11910-017-0767-5. Review.

8.

Low-molecular-weight heparins or heparinoids versus standard unfractionated heparin for acute ischaemic stroke.

Sandercock PA, Leong TS.

Cochrane Database Syst Rev. 2017 Apr 4;4:CD000119. doi: 10.1002/14651858.CD000119.pub4. Review.

9.

Cerebral White Matter Hypoperfusion Increases with Small-Vessel Disease Burden. Data From the Third International Stroke Trial.

Arba F, Mair G, Carpenter T, Sakka E, Sandercock PAG, Lindley RI, Inzitari D, Wardlaw JM; IST-3 Trial Collaborators.

J Stroke Cerebrovasc Dis. 2017 Jul;26(7):1506-1513. doi: 10.1016/j.jstrokecerebrovasdis.2017.03.002. Epub 2017 Mar 15.

PMID:
28314624
10.

Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke.

Mair G, von Kummer R, Adami A, White PM, Adams ME, Yan B, Demchuk AM, Farrall AJ, Sellar RJ, Sakka E, Palmer J, Perry D, Lindley RI, Sandercock PA, Wardlaw JM; IST-3 Collaborative Group.

Stroke. 2017 Feb;48(2):353-360. doi: 10.1161/STROKEAHA.116.015164. Epub 2016 Dec 22.

11.

Mortality after thrombolysis - Authors' reply.

Berge E, Cohen G, Wardlaw JM, Sandercock PAG, Whiteley WN.

Lancet Neurol. 2016 Dec;15(13):1305. doi: 10.1016/S1474-4422(16)30280-0. No abstract available.

PMID:
27839642
12.

Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes: A Pooled Analysis of 9 Trials.

Lees KR, Emberson J, Blackwell L, Bluhmki E, Davis SM, Donnan GA, Grotta JC, Kaste M, von Kummer R, Lansberg MG, Lindley RI, Lyden P, Murray GD, Sandercock PA, Toni D, Toyoda K, Wardlaw JM, Whiteley WN, Baigent C, Hacke W, Howard G; Stroke Thrombolysis Trialists’ Collaborators Group.

Stroke. 2016 Sep;47(9):2373-9. doi: 10.1161/STROKEAHA.116.013644. Epub 2016 Aug 9.

13.

Effects of alteplase on survival after ischaemic stroke (IST-3): 3 year follow-up of a randomised, controlled, open-label trial.

Berge E, Cohen G, Roaldsen MB, Lundström E, Isaksson E, Rudberg AS, Slot KB, Forbes J, Smith J, Drever J, Wardlaw JM, Lindley RI, Sandercock PA, Whiteley WN; IST-3 Collaborative Group.

Lancet Neurol. 2016 Sep;15(10):1028-34. doi: 10.1016/S1474-4422(16)30139-9. Epub 2016 Jul 20.

PMID:
27450474
14.

The forecast for future clinical trials and clinical trialists-Storms or sunshine?

Klijn CJ, Sandercock PA.

Int J Stroke. 2016 Oct;11(7):738-40. doi: 10.1177/1747493016655362. Epub 2016 Jun 17.

PMID:
27316456
15.

Author Response.

Wardlaw JM, Brazzelli M, Chappell F, Dennis MS, Sandercock PA.

Neurology. 2016 Feb 16;86(7):697. No abstract available.

PMID:
27303783
16.

Effect of X-Ray Attenuation of Arterial Obstructions on Intravenous Thrombolysis and Outcome after Ischemic Stroke.

Mair G, von Kummer R, Lindley RI, Sandercock PA, Wardlaw JM; IST-3 Collaborative Group.

PLoS One. 2015 Dec 23;10(12):e0145683. doi: 10.1371/journal.pone.0145683. eCollection 2015.

17.

Effect of alteplase on the CT hyperdense artery sign and outcome after ischemic stroke.

Mair G, von Kummer R, Morris Z, von Heijne A, Bradey N, Cala L, Peeters A, Farrall AJ, Adami A, Potter G, Cohen G, Sandercock PA, Lindley RI, Wardlaw JM; IST-3 Collaborative Group.

Neurology. 2016 Jan 12;86(2):118-25. doi: 10.1212/WNL.0000000000002236. Epub 2015 Dec 9.

18.

Does personalized medicine exist and can you test it in a clinical trial?

Sandercock PA.

Int J Stroke. 2015 Oct;10(7):994-9. doi: 10.1111/ijs.12597. Epub 2015 Aug 18. Review.

PMID:
26282857
19.

ABCD2 score and secondary stroke prevention: meta-analysis and effect per 1,000 patients triaged.

Wardlaw JM, Brazzelli M, Chappell FM, Miranda H, Shuler K, Sandercock PA, Dennis MS.

Neurology. 2015 Jul 28;85(4):373-80. doi: 10.1212/WNL.0000000000001780. Epub 2015 Jul 1. Review.

20.

Short History of Confidence Intervals: Or, Don't Ask "Does the Treatment Work?" but "How Sure Are You That It Works?".

Sandercock PA.

Stroke. 2015 Aug;46(8):e184-7. doi: 10.1161/STROKEAHA.115.007750. Epub 2015 Jun 23. Review. No abstract available.

PMID:
26106115
21.

A call to revolutionise acute stroke care and research.

Sandercock PA.

Lancet Neurol. 2015 Jul;14(7):674-5. doi: 10.1016/S1474-4422(15)00088-5. No abstract available.

PMID:
26067109
22.

Targeting aspirin in acute disabling ischemic stroke: an individual patient data meta-analysis of three large randomized trials.

Thompson DD, Murray GD, Candelise L, Chen Z, Sandercock PA, Whiteley WN.

Int J Stroke. 2015 Oct;10(7):1024-30. doi: 10.1111/ijs.12487. Epub 2015 Apr 12. Review.

23.

Anticoagulants for acute ischaemic stroke.

Sandercock PA, Counsell C, Kane EJ.

Cochrane Database Syst Rev. 2015 Mar 12;(3):CD000024. doi: 10.1002/14651858.CD000024.pub4. Review.

PMID:
25764172
25.

Alteplase for acute ischemic stroke: outcomes by clinically important subgroups in the Third International Stroke Trial.

Lindley RI, Wardlaw JM, Whiteley WN, Cohen G, Blackwell L, Murray GD, Sandercock PA; IST-3 Collaborative Group.

Stroke. 2015 Mar;46(3):746-56. doi: 10.1161/STROKEAHA.114.006573. Epub 2015 Jan 22. Erratum in: Stroke. 2015 Mar;46(3):e73.

PMID:
25613308
26.

Observer reliability of CT angiography in the assessment of acute ischaemic stroke: data from the Third International Stroke Trial.

Mair G, von Kummer R, Adami A, White PM, Adams ME, Yan B, Demchuk AM, Farrall AJ, Sellar RJ, Ramaswamy R, Mollison D, Boyd EV, Rodrigues MA, Samji K, Baird AJ, Cohen G, Sakka E, Palmer J, Perry D, Lindley R, Sandercock PA, Wardlaw JM; IST-3 Collaborative Group.

Neuroradiology. 2015 Jan;57(1):1-9. doi: 10.1007/s00234-014-1441-0. Epub 2014 Oct 7.

27.

Oral antiplatelet therapy for acute ischaemic stroke.

Sandercock PA, Counsell C, Tseng MC, Cecconi E.

Cochrane Database Syst Rev. 2014 Mar 26;(3):CD000029. doi: 10.1002/14651858.CD000029.pub3. Review.

28.

Diffusion-weighted imaging and diagnosis of transient ischemic attack.

Brazzelli M, Chappell FM, Miranda H, Shuler K, Dennis M, Sandercock PA, Muir K, Wardlaw JM.

Ann Neurol. 2014 Jan;75(1):67-76. doi: 10.1002/ana.24026. Epub 2014 Jan 2.

29.

Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials.

Whiteley WN, Adams HP Jr, Bath PM, Berge E, Sandset PM, Dennis M, Murray GD, Wong KS, Sandercock PA.

Lancet Neurol. 2013 Jun;12(6):539-45. doi: 10.1016/S1474-4422(13)70079-6. Epub 2013 May 2.

30.

Protocol for the perfusion and angiography imaging sub-study of the Third International Stroke Trial (IST-3) of alteplase treatment within six-hours of acute ischemic stroke.

Wardlaw JM, von Kummer R, Carpenter T, Parsons M, Lindley RI, Cohen G, Murray V, Kobayashi A, Peeters A, Chappell F, Sandercock PA.

Int J Stroke. 2015 Aug;10(6):956-68. doi: 10.1111/j.1747-4949.2012.00946.x. Epub 2013 Jan 22.

31.

An old drug for a common disease.

Cantisani TA, Celani MG, Hankey GJ, Sandercock PA.

J Neurol Neurosurg Psychiatry. 2013 May;84(5):473-4. doi: 10.1136/jnnp-2012-304183. Epub 2012 Dec 12. No abstract available.

PMID:
23236015
32.

Secondary progressive multiple sclerosis: a shared therapeutic decision.

Cantisani TA, Celani MG, Hankey GJ, Sandercock PA.

J Neurol Neurosurg Psychiatry. 2013 Apr;84(4):365. doi: 10.1136/jnnp-2012-303884. Epub 2012 Dec 6. No abstract available.

PMID:
23223334
33.

Improving the process of translational research.

van der Worp HB, Sandercock PA.

BMJ. 2012 Nov 23;345:e7837. doi: 10.1136/bmj.e7837. No abstract available.

PMID:
23179868
34.

Corticosteroids for acute ischaemic stroke.

Sandercock PA, Soane T.

Cochrane Database Syst Rev. 2011 Sep 7;(9):CD000064. doi: 10.1002/14651858.CD000064.pub2. Review.

PMID:
21901674
35.

The International Stroke Trial database.

Sandercock PA, Niewada M, Członkowska A; International Stroke Trial Collaborative Group.

Trials. 2011 Apr 21;12:101. doi: 10.1186/1745-6215-12-101. Erratum in: Trials. 2012;13:24.

36.

Planning trials in older patients with stroke: data from the International Stroke Trial.

Niewada M, Sandercock PA, Lindley RI, Członkowska A.

Age Ageing. 2011 May;40(3):395-8. doi: 10.1093/ageing/afr030. Epub 2011 Mar 28. No abstract available.

PMID:
21447486
37.

Fatigue after stroke: baseline predictors and influence on survival. Analysis of data from UK patients recruited in the International Stroke Trial.

Mead GE, Graham C, Dorman P, Bruins SK, Lewis SC, Dennis MS, Sandercock PA; UK Collaborators of IST.

PLoS One. 2011 Mar 18;6(3):e16988. doi: 10.1371/journal.pone.0016988.

38.

Clinical scores for the identification of stroke and transient ischaemic attack in the emergency department: a cross-sectional study.

Whiteley WN, Wardlaw JM, Dennis MS, Sandercock PA.

J Neurol Neurosurg Psychiatry. 2011 Sep;82(9):1006-10. doi: 10.1136/jnnp.2010.235010. Epub 2011 Mar 14.

PMID:
21402744
39.

Thrombolysis in elderly people. Observational data insufficient to change treatment.

Lindley RI, Wardlaw JM, Sandercock PA.

BMJ. 2011 Jan 19;342:d306; author reply d312. doi: 10.1136/bmj.d306. No abstract available.

PMID:
21248009
40.

Physical methods for preventing deep vein thrombosis in stroke.

Naccarato M, Chiodo Grandi F, Dennis M, Sandercock PA.

Cochrane Database Syst Rev. 2010 Aug 4;(8):CD001922. doi: 10.1002/14651858.CD001922.pub3. Review.

PMID:
20687069
41.

Factors affecting the apparent efficacy and safety of tissue plasminogen activator in thrombotic occlusion models of stroke: systematic review and meta-analysis.

Sena ES, Briscoe CL, Howells DW, Donnan GA, Sandercock PA, Macleod MR.

J Cereb Blood Flow Metab. 2010 Dec;30(12):1905-13. doi: 10.1038/jcbfm.2010.116. Epub 2010 Jul 21. Review.

42.

How beneficial is surgery for cervical radiculopathy and myelopathy?

Fouyas IP, Sandercock PA, Statham PF, Nikolaidis I.

BMJ. 2010 Jul 13;341:c3108. doi: 10.1136/bmj.c3108. No abstract available.

PMID:
20627982
43.

A systematic review of clinical trials of pharmacological interventions for acute ischaemic stroke (1955-2008) that were completed, but not published in full.

Gibson LM, Brazzelli M, Thomas BM, Sandercock PA.

Trials. 2010 Apr 22;11:43. doi: 10.1186/1745-6215-11-43. Review.

44.

Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trial.

Fowkes FG, Price JF, Stewart MC, Butcher I, Leng GC, Pell AC, Sandercock PA, Fox KA, Lowe GD, Murray GD; Aspirin for Asymptomatic Atherosclerosis Trialists.

JAMA. 2010 Mar 3;303(9):841-8. doi: 10.1001/jama.2010.221.

PMID:
20197530
45.

The molecular basis of thrombolysis and its clinical application in stroke.

Murray V, Norrving B, Sandercock PA, Terént A, Wardlaw JM, Wester P.

J Intern Med. 2010 Feb;267(2):191-208. doi: 10.1111/j.1365-2796.2009.02205.x. Review.

46.

Surgery for cervical radiculopathy or myelopathy.

Nikolaidis I, Fouyas IP, Sandercock PA, Statham PF.

Cochrane Database Syst Rev. 2010 Jan 20;(1):CD001466. doi: 10.1002/14651858.CD001466.pub3. Review.

PMID:
20091520
47.

Should more patients with acute ischaemic stroke receive thrombolytic treatment?

Wardlaw JM, Sandercock PA, Murray V.

BMJ. 2009 Nov 11;339:b4584. doi: 10.1136/bmj.b4584. No abstract available.

PMID:
19906748
48.

Magnetic resonance imaging versus computed tomography for detection of acute vascular lesions in patients presenting with stroke symptoms.

Brazzelli M, Sandercock PA, Chappell FM, Celani MG, Righetti E, Arestis N, Wardlaw JM, Deeks JJ.

Cochrane Database Syst Rev. 2009 Oct 7;(4):CD007424. doi: 10.1002/14651858.CD007424.pub2. Review.

PMID:
19821415
49.

Effectiveness of thigh-length graduated compression stockings to reduce the risk of deep vein thrombosis after stroke (CLOTS trial 1): a multicentre, randomised controlled trial.

CLOTS Trials Collaboration, Dennis M, Sandercock PA, Reid J, Graham C, Murray G, Venables G, Rudd A, Bowler G.

Lancet. 2009 Jun 6;373(9679):1958-65. doi: 10.1016/S0140-6736(09)60941-7. Epub 2009 May 26.

50.

Anticoagulants for preventing recurrence following presumed non-cardioembolic ischaemic stroke or transient ischaemic attack.

Sandercock PA, Gibson LM, Liu M.

Cochrane Database Syst Rev. 2009 Apr 15;(2):CD000248. doi: 10.1002/14651858.CD000248.pub2. Review.

PMID:
19370555

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