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Items: 1 to 50 of 116

1.

Characterization of Arabidopsis thaliana promoter Bidirectionality and Antisense RNAs by Depletion of Nuclear RNA Decay Pathways.

Thieffry A, Vigh ML, Bornholdt J, Ivanov M, Brodersen P, Sandelin A.

Plant Cell. 2020 Mar 25. pii: tpc.00815.2019. doi: 10.1105/tpc.19.00815. [Epub ahead of print]

PMID:
32213639
2.

Field trial to evaluate the effect of an intranasal respiratory vaccine protocol on bovine respiratory disease incidence and growth in a commercial calf rearing unit.

Sandelin A, Härtel H, Seppä-Lassila L, Kaartinen L, Rautala H, Soveri T, Simojoki H.

BMC Vet Res. 2020 Mar 4;16(1):73. doi: 10.1186/s12917-020-02294-7.

3.

Organismal benefits of transcription speed control at gene boundaries.

Leng X, Ivanov M, Kindgren P, Malik I, Thieffry A, Brodersen P, Sandelin A, Kaplan CD, Marquardt S.

EMBO Rep. 2020 Feb 27:e49315. doi: 10.15252/embr.201949315. [Epub ahead of print]

PMID:
32103605
4.

A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome.

Wu G, Schmid M, Rib L, Polak P, Meola N, Sandelin A, Jensen TH.

Cell Rep. 2020 Feb 18;30(7):2387-2401.e5. doi: 10.1016/j.celrep.2020.01.068.

5.

Lactobacillus rhamnosus GG Genomic and Phenotypic Stability in an Industrial Production Process.

Stage M, Wichmann A, Jørgensen M, Vera-Jimenéz NI, Wielje M, Nielsen DS, Sandelin A, Chen Y, Baker A.

Appl Environ Microbiol. 2020 Mar 2;86(6). pii: e02780-19. doi: 10.1128/AEM.02780-19. Print 2020 Mar 2.

PMID:
31924618
6.

A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2.

Garland W, Comet I, Wu M, Radzisheuskaya A, Rib L, Vitting-Seerup K, Lloret-Llinares M, Sandelin A, Helin K, Jensen TH.

Cell Rep. 2019 Nov 12;29(7):1800-1811.e6. doi: 10.1016/j.celrep.2019.10.011.

7.

JASPAR 2020: update of the open-access database of transcription factor binding profiles.

Fornes O, Castro-Mondragon JA, Khan A, van der Lee R, Zhang X, Richmond PA, Modi BP, Correard S, Gheorghe M, Baranašić D, Santana-Garcia W, Tan G, Chèneby J, Ballester B, Parcy F, Sandelin A, Lenhard B, Wasserman WW, Mathelier A.

Nucleic Acids Res. 2020 Jan 8;48(D1):D87-D92. doi: 10.1093/nar/gkz1001.

PMID:
31701148
8.

Determinants of enhancer and promoter activities of regulatory elements.

Andersson R, Sandelin A.

Nat Rev Genet. 2020 Feb;21(2):71-87. doi: 10.1038/s41576-019-0173-8. Epub 2019 Oct 11. Review.

PMID:
31605096
9.

CAGEfightR: analysis of 5'-end data using R/Bioconductor.

Thodberg M, Thieffry A, Vitting-Seerup K, Andersson R, Sandelin A.

BMC Bioinformatics. 2019 Oct 4;20(1):487. doi: 10.1186/s12859-019-3029-5.

10.

A step-by-step guide to analyzing CAGE data using R/Bioconductor.

Thodberg M, Sandelin A.

F1000Res. 2019 Jun 18;8:886. doi: 10.12688/f1000research.18456.1. eCollection 2019.

11.

IsoformSwitchAnalyzeR: analysis of changes in genome-wide patterns of alternative splicing and its functional consequences.

Vitting-Seerup K, Sandelin A.

Bioinformatics. 2019 Nov 1;35(21):4469-4471. doi: 10.1093/bioinformatics/btz247.

PMID:
30989184
12.

Prerequisites for safe intraoperative nursing care and teamwork-Operating theatre nurses' perspectives: A qualitative interview study.

Sandelin A, Kalman S, Gustafsson BÅ.

J Clin Nurs. 2019 Jul;28(13-14):2635-2643. doi: 10.1111/jocn.14850. Epub 2019 Mar 29.

PMID:
30865340
13.

PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells.

Agrawal Singh S, Lerdrup M, Gomes AR, van de Werken HJ, Vilstrup Johansen J, Andersson R, Sandelin A, Helin K, Hansen K.

Elife. 2019 Jan 23;8. pii: e40364. doi: 10.7554/eLife.40364.

14.

Comprehensive profiling of the fission yeast transcription start site activity during stress and media response.

Thodberg M, Thieffry A, Bornholdt J, Boyd M, Holmberg C, Azad A, Workman CT, Chen Y, Ekwall K, Nielsen O, Sandelin A.

Nucleic Acids Res. 2019 Feb 28;47(4):1671-1691. doi: 10.1093/nar/gky1227.

15.

The RNA exosome contributes to gene expression regulation during stem cell differentiation.

Lloret-Llinares M, Karadoulama E, Chen Y, Wojenski LA, Villafano GJ, Bornholdt J, Andersson R, Core L, Sandelin A, Jensen TH.

Nucleic Acids Res. 2018 Nov 30;46(21):11502-11513. doi: 10.1093/nar/gky817.

16.

Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies.

Boyd M, Thodberg M, Vitezic M, Bornholdt J, Vitting-Seerup K, Chen Y, Coskun M, Li Y, Lo BZS, Klausen P, Jan Schweiger P, Pedersen AG, Rapin N, Skovgaard K, Dahlgaard K, Andersson R, Terkelsen TB, Lilje B, Troelsen JT, Petersen AM, Jensen KB, Gögenur I, Thielsen P, Seidelin JB, Nielsen OH, Bjerrum JT, Sandelin A.

Nat Commun. 2018 Apr 25;9(1):1661. doi: 10.1038/s41467-018-03766-z.

17.

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

Baillie JK, Bretherick A, Haley CS, Clohisey S, Gray A, Neyton LPA, Barrett J, Stahl EA, Tenesa A, Andersson R, Brown JB, Faulkner GJ, Lizio M, Schaefer U, Daub C, Itoh M, Kondo N, Lassmann T, Kawai J; IIBDGC Consortium, Mole D, Bajic VB, Heutink P, Rehli M, Kawaji H, Sandelin A, Suzuki H, Satsangi J, Wells CA, Hacohen N, Freeman TC, Hayashizaki Y, Carninci P, Forrest ARR, Hume DA.

PLoS Comput Biol. 2018 Mar 1;14(3):e1005934. doi: 10.1371/journal.pcbi.1005934. eCollection 2018 Mar.

18.

Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels.

Chen Y, Salem M, Boyd M, Bornholdt J, Li Y, Coskun M, Seidelin JB, Sandelin A, Nielsen OH.

NPJ Genom Med. 2017 Feb 8;2:3. doi: 10.1038/s41525-016-0001-4. eCollection 2017.

19.

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework.

Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Chèneby J, Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, Ballester B, Wasserman WW, Parcy F, Mathelier A.

Nucleic Acids Res. 2018 Jan 4;46(D1):D1284. doi: 10.1093/nar/gkx1188. No abstract available.

20.

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework.

Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Chèneby J, Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, Ballester B, Wasserman WW, Parcy F, Mathelier A.

Nucleic Acids Res. 2018 Jan 4;46(D1):D260-D266. doi: 10.1093/nar/gkx1126. Erratum in: Nucleic Acids Res. 2018 Jan 4;46(D1):D1284.

21.

An integrated expression atlas of miRNAs and their promoters in human and mouse.

de Rie D, Abugessaisa I, Alam T, Arner E, Arner P, Ashoor H, Åström G, Babina M, Bertin N, Burroughs AM, Carlisle AJ, Daub CO, Detmar M, Deviatiiarov R, Fort A, Gebhard C, Goldowitz D, Guhl S, Ha TJ, Harshbarger J, Hasegawa A, Hashimoto K, Herlyn M, Heutink P, Hitchens KJ, Hon CC, Huang E, Ishizu Y, Kai C, Kasukawa T, Klinken P, Lassmann T, Lecellier CH, Lee W, Lizio M, Makeev V, Mathelier A, Medvedeva YA, Mejhert N, Mungall CJ, Noma S, Ohshima M, Okada-Hatakeyama M, Persson H, Rizzu P, Roudnicky F, Sætrom P, Sato H, Severin J, Shin JW, Swoboda RK, Tarui H, Toyoda H, Vitting-Seerup K, Winteringham L, Yamaguchi Y, Yasuzawa K, Yoneda M, Yumoto N, Zabierowski S, Zhang PG, Wells CA, Summers KM, Kawaji H, Sandelin A, Rehli M; FANTOM Consortium, Hayashizaki Y, Carninci P, Forrest ARR, de Hoon MJL.

Nat Biotechnol. 2017 Sep;35(9):872-878. doi: 10.1038/nbt.3947. Epub 2017 Aug 21.

22.

Oxygen-induced impairment in arterial function is corrected by slow breathing in patients with type 1 diabetes.

Bernardi L, Gordin D, Bordino M, Rosengård-Bärlund M, Sandelin A, Forsblom C, Groop PH.

Sci Rep. 2017 Jul 20;7(1):6001. doi: 10.1038/s41598-017-04947-4.

23.

The Landscape of Isoform Switches in Human Cancers.

Vitting-Seerup K, Sandelin A.

Mol Cancer Res. 2017 Sep;15(9):1206-1220. doi: 10.1158/1541-7786.MCR-16-0459. Epub 2017 Jun 5.

24.

Identification of Gene Transcription Start Sites and Enhancers Responding to Pulmonary Carbon Nanotube Exposure in Vivo.

Bornholdt J, Saber AT, Lilje B, Boyd M, Jørgensen M, Chen Y, Vitezic M, Jacobsen NR, Poulsen SS, Berthing T, Bressendorff S, Vitting-Seerup K, Andersson R, Hougaard KS, Yauk CL, Halappanavar S, Wallin H, Vogel U, Sandelin A.

ACS Nano. 2017 Apr 25;11(4):3597-3613. doi: 10.1021/acsnano.6b07533. Epub 2017 Mar 31.

PMID:
28345861
25.

On-the-fly selection of cell-specific enhancers, genes, miRNAs and proteins across the human body using SlideBase.

Ienasescu H, Li K, Andersson R, Vitezic M, Rennie S, Chen Y, Vitting-Seerup K, Lagoni E, Boyd M, Bornholdt J, de Hoon MJ, Kawaji H, Lassmann T; FANTOM Consortium, Hayashizaki Y, Forrest AR, Carninci P, Sandelin A.

Database (Oxford). 2016 Dec 26;2016. pii: baw144. doi: 10.1093/database/baw144. Print 2016.

26.

Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.

Meola N, Domanski M, Karadoulama E, Chen Y, Gentil C, Pultz D, Vitting-Seerup K, Lykke-Andersen S, Andersen JS, Sandelin A, Jensen TH.

Mol Cell. 2016 Nov 3;64(3):520-533. doi: 10.1016/j.molcel.2016.09.025. Epub 2016 Oct 27.

27.

Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution.

Ehrlund A, Mejhert N, Björk C, Andersson R, Kulyté A, Åström G, Itoh M, Kawaji H, Lassmann T, Daub CO, Carninci P, Forrest AR, Hayashizaki Y, Sandelin A, Ingelsson E; FANTOM Consortium, Rydén M, Laurencikiene J, Arner P, Arner E.

Diabetes. 2017 Jan;66(1):218-230. doi: 10.2337/db16-0631. Epub 2016 Nov 1.

28.

Update of the FANTOM web resource: high resolution transcriptome of diverse cell types in mammals.

Lizio M, Harshbarger J, Abugessaisa I, Noguchi S, Kondo A, Severin J, Mungall C, Arenillas D, Mathelier A, Medvedeva YA, Lennartsson A, Drabløs F, Ramilowski JA, Rackham O, Gough J, Andersson R, Sandelin A, Ienasescu H, Ono H, Bono H, Hayashizaki Y, Carninci P, Forrest AR, Kasukawa T, Kawaji H.

Nucleic Acids Res. 2017 Jan 4;45(D1):D737-D743. doi: 10.1093/nar/gkw995. Epub 2016 Oct 27.

29.

The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity.

Rydén M, Hrydziuszko O, Mileti E, Raman A, Bornholdt J, Boyd M, Toft E, Qvist V, Näslund E, Thorell A, Andersson DP, Dahlman I, Gao H, Sandelin A, Daub CO, Arner P.

Cell Rep. 2016 Aug 30;16(9):2317-26. doi: 10.1016/j.celrep.2016.07.070. Epub 2016 Aug 18.

30.

Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters.

Chen Y, Pai AA, Herudek J, Lubas M, Meola N, Järvelin AI, Andersson R, Pelechano V, Steinmetz LM, Jensen TH, Sandelin A.

Nat Genet. 2016 Sep;48(9):984-94. doi: 10.1038/ng.3616. Epub 2016 Jul 25.

31.

Regulation of Laminin γ2 Expression by CDX2 in Colonic Epithelial Cells Is Impaired During Active Inflammation.

Coskun M, Soendergaard C, Joergensen S, Dahlgaard K, Riis LB, Nielsen OH, Sandelin A, Troelsen JT.

J Cell Biochem. 2017 Feb;118(2):298-307. doi: 10.1002/jcb.25636. Epub 2016 Jun 29.

PMID:
27333824
32.

Corrigendum: Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes.

Lykke-Andersen S, Chen Y, Ardal BR, Lilje B, Waage J, Sandelin A, Jensen TH.

Genes Dev. 2016 May 1;30(9):1128-34. doi: 10.1101/gad.281881.116. No abstract available.

33.

Regulating retrotransposon activity through the use of alternative transcription start sites.

Persson J, Steglich B, Smialowska A, Boyd M, Bornholdt J, Andersson R, Schurra C, Arcangioli B, Sandelin A, Nielsen O, Ekwall K.

EMBO Rep. 2016 May;17(5):753-68. doi: 10.15252/embr.201541866. Epub 2016 Feb 22.

34.

Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticity by HDAC inhibitors.

Lennartsson A, Arner E, Fagiolini M, Saxena A, Andersson R, Takahashi H, Noro Y, Sng J, Sandelin A, Hensch TK, Carninci P.

Epigenetics Chromatin. 2015 Dec 14;8:55. doi: 10.1186/s13072-015-0043-3. eCollection 2015.

35.

Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers.

Kaczkowski B, Tanaka Y, Kawaji H, Sandelin A, Andersson R, Itoh M, Lassmann T, Hayashizaki Y, Carninci P, Forrest AR; FANTOM5 Consortium.

Cancer Res. 2016 Jan 15;76(2):216-26. doi: 10.1158/0008-5472.CAN-15-0484. Epub 2015 Nov 9.

36.

The Swedish fracture register: 103,000 fractures registered.

Wennergren D, Ekholm C, Sandelin A, Möller M.

BMC Musculoskelet Disord. 2015 Nov 6;16:338. doi: 10.1186/s12891-015-0795-8.

37.

Human Gene Promoters Are Intrinsically Bidirectional.

Andersson R, Chen Y, Core L, Lis JT, Sandelin A, Jensen TH.

Mol Cell. 2015 Nov 5;60(3):346-7. doi: 10.1016/j.molcel.2015.10.015. No abstract available.

38.

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles.

Mathelier A, Fornes O, Arenillas DJ, Chen CY, Denay G, Lee J, Shi W, Shyr C, Tan G, Worsley-Hunt R, Zhang AW, Parcy F, Lenhard B, Sandelin A, Wasserman WW.

Nucleic Acids Res. 2016 Jan 4;44(D1):D110-5. doi: 10.1093/nar/gkv1176. Epub 2015 Nov 3.

39.

The frequent evolutionary birth and death of functional promoters in mouse and human.

Young RS, Hayashizaki Y, Andersson R, Sandelin A, Kawaji H, Itoh M, Lassmann T, Carninci P; FANTOM Consortium, Bickmore WA, Forrest AR, Taylor MS.

Genome Res. 2015 Oct;25(10):1546-57. doi: 10.1101/gr.190546.115. Epub 2015 Jul 30.

40.

Oxygen deteriorates arterial function in type 1 diabetes.

Gordin D, Bernardi L, Rosengård-Bärlund M, Mäkinen VP, Soro-Paavonen A, Forsblom C, Sandelin A, Groop PH.

Acta Diabetol. 2016 Jun;53(3):349-57. doi: 10.1007/s00592-015-0775-3. Epub 2015 Jul 11.

PMID:
26159114
41.

A unified architecture of transcriptional regulatory elements.

Andersson R, Sandelin A, Danko CG.

Trends Genet. 2015 Aug;31(8):426-33. doi: 10.1016/j.tig.2015.05.007. Epub 2015 Jun 11. Review.

PMID:
26073855
42.

Gateways to the FANTOM5 promoter level mammalian expression atlas.

Lizio M, Harshbarger J, Shimoji H, Severin J, Kasukawa T, Sahin S, Abugessaisa I, Fukuda S, Hori F, Ishikawa-Kato S, Mungall CJ, Arner E, Baillie JK, Bertin N, Bono H, de Hoon M, Diehl AD, Dimont E, Freeman TC, Fujieda K, Hide W, Kaliyaperumal R, Katayama T, Lassmann T, Meehan TF, Nishikata K, Ono H, Rehli M, Sandelin A, Schultes EA, 't Hoen PA, Tatum Z, Thompson M, Toyoda T, Wright DW, Daub CO, Itoh M, Carninci P, Hayashizaki Y, Forrest AR, Kawaji H; FANTOM consortium.

Genome Biol. 2015 Jan 5;16:22. doi: 10.1186/s13059-014-0560-6.

43.

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Arner E, Daub CO, Vitting-Seerup K, Andersson R, Lilje B, Drabløs F, Lennartsson A, Rönnerblad M, Hrydziuszko O, Vitezic M, Freeman TC, Alhendi AM, Arner P, Axton R, Baillie JK, Beckhouse A, Bodega B, Briggs J, Brombacher F, Davis M, Detmar M, Ehrlund A, Endoh M, Eslami A, Fagiolini M, Fairbairn L, Faulkner GJ, Ferrai C, Fisher ME, Forrester L, Goldowitz D, Guler R, Ha T, Hara M, Herlyn M, Ikawa T, Kai C, Kawamoto H, Khachigian LM, Klinken SP, Kojima S, Koseki H, Klein S, Mejhert N, Miyaguchi K, Mizuno Y, Morimoto M, Morris KJ, Mummery C, Nakachi Y, Ogishima S, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov D, Passier R, Patrikakis M, Pombo A, Qin XY, Roy S, Sato H, Savvi S, Saxena A, Schwegmann A, Sugiyama D, Swoboda R, Tanaka H, Tomoiu A, Winteringham LN, Wolvetang E, Yanagi-Mizuochi C, Yoneda M, Zabierowski S, Zhang P, Abugessaisa I, Bertin N, Diehl AD, Fukuda S, Furuno M, Harshbarger J, Hasegawa A, Hori F, Ishikawa-Kato S, Ishizu Y, Itoh M, Kawashima T, Kojima M, Kondo N, Lizio M, Meehan TF, Mungall CJ, Murata M, Nishiyori-Sueki H, Sahin S, Nagao-Sato S, Severin J, de Hoon MJ, Kawai J, Kasukawa T, Lassmann T, Suzuki H, Kawaji H, Summers KM, Wells C; FANTOM Consortium, Hume DA, Forrest AR, Sandelin A, Carninci P, Hayashizaki Y.

Science. 2015 Feb 27;347(6225):1010-4. doi: 10.1126/science.1259418. Epub 2015 Feb 12.

44.

CAGE-defined promoter regions of the genes implicated in Rett Syndrome.

Vitezic M, Bertin N, Andersson R, Lipovich L, Kawaji H, Lassmann T, Sandelin A, Heutink P, Goldowitz D, Ha T, Zhang P, Patrizi A, Fagiolini M, Forrest AR, Carninci P, Saxena A; FANTOM Consortium.

BMC Genomics. 2014 Dec 24;15:1177. doi: 10.1186/1471-2164-15-1177.

45.

Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes.

Lykke-Andersen S, Chen Y, Ardal BR, Lilje B, Waage J, Sandelin A, Jensen TH.

Genes Dev. 2014 Nov 15;28(22):2498-517. doi: 10.1101/gad.246538.114. Erratum in: Genes Dev. 2016 May 1;30(9):1128-34.

46.

Nuclear stability and transcriptional directionality separate functionally distinct RNA species.

Andersson R, Refsing Andersen P, Valen E, Core LJ, Bornholdt J, Boyd M, Heick Jensen T, Sandelin A.

Nat Commun. 2014 Nov 12;5:5336. doi: 10.1038/ncomms6336.

PMID:
25387874
47.

Creating an environment for patient safety and teamwork training in the operating theatre: A quasi-experimental study.

Wallin CJ, Kalman S, Sandelin A, Färnert ML, Dahlstrand U, Jylli L.

Med Teach. 2015 Mar;37(3):267-76. doi: 10.3109/0142159X.2014.947927. Epub 2014 Sep 2.

PMID:
25180879
48.

Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2.

Boyd M, Coskun M, Lilje B, Andersson R, Hoof I, Bornholdt J, Dahlgaard K, Olsen J, Vitezic M, Bjerrum JT, Seidelin JB, Nielsen OH, Troelsen JT, Sandelin A.

DNA Res. 2014 Dec;21(6):569-83. doi: 10.1093/dnares/dsu022. Epub 2014 Jul 2.

49.

Molecular architecture of transcription factor hotspots in early adipogenesis.

Siersbæk R, Baek S, Rabiee A, Nielsen R, Traynor S, Clark N, Sandelin A, Jensen ON, Sung MH, Hager GL, Mandrup S.

Cell Rep. 2014 Jun 12;7(5):1434-1442. doi: 10.1016/j.celrep.2014.04.043. Epub 2014 May 22.

50.

Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance.

Fort A, Hashimoto K, Yamada D, Salimullah M, Keya CA, Saxena A, Bonetti A, Voineagu I, Bertin N, Kratz A, Noro Y, Wong CH, de Hoon M, Andersson R, Sandelin A, Suzuki H, Wei CL, Koseki H; FANTOM Consortium, Hasegawa Y, Forrest AR, Carninci P.

Nat Genet. 2014 Jun;46(6):558-66. doi: 10.1038/ng.2965. Epub 2014 Apr 28.

PMID:
24777452

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