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LUBAC determines chemotherapy resistance in squamous cell lung cancer.

Ruiz EJ, Diefenbacher ME, Nelson JK, Sancho R, Pucci F, Chakraborty A, Moreno P, Annibaldi A, Liccardi G, Encheva V, Mitter R, Rosenfeldt M, Snijders AP, Meier P, Calzado MA, Behrens A.

J Exp Med. 2019 Feb 4;216(2):450-465. doi: 10.1084/jem.20180742. Epub 2019 Jan 14.


Stress-inducible-stem cells: a new view on endocrine, metabolic and mental disease?

Bornstein SR, Steenblock C, Chrousos GP, Schally AV, Beuschlein F, Kline G, Krone NP, Licinio J, Wong ML, Ullmann E, Ruiz-Babot G, Boehm BO, Behrens A, Brennand A, Santambrogio A, Berger I, Werdermann M, Sancho R, Linkermann A, Lenders JW, Eisenhofer G, Andoniadou CL.

Mol Psychiatry. 2019 Jan;24(1):2-9. doi: 10.1038/s41380-018-0244-9. Epub 2018 Sep 21. No abstract available.


Reconstructing the origins and the biogeography of species' genomes in the highly reticulate allopolyploid-rich model grass genus Brachypodium using minimum evolution, coalescence and maximum likelihood approaches.

Díaz-Pérez A, López-Álvarez D, Sancho R, Catalán P.

Mol Phylogenet Evol. 2018 Oct;127:256-271. doi: 10.1016/j.ympev.2018.06.003. Epub 2018 Jun 4.


Phenotypic plasticity in the pancreas: new triggers, new players.

Demcollari TI, Cujba AM, Sancho R.

Curr Opin Cell Biol. 2017 Dec;49:38-46. doi: 10.1016/ Epub 2017 Dec 8. Review.


Comparative plastome genomics and phylogenomics of Brachypodium: flowering time signatures, introgression and recombination in recently diverged ecotypes.

Sancho R, Cantalapiedra CP, López-Alvarez D, Gordon SP, Vogel JP, Catalán P, Contreras-Moreira B.

New Phytol. 2018 Jun;218(4):1631-1644. doi: 10.1111/nph.14926. Epub 2017 Dec 5.


Acetabular overcoverage in the horizontal plane: an underdiagnosed trigger of early hip arthritis. A CT scan study in young adults.

Valera M, Ibáñez N, Sancho R, Llauger J, Gich I.

Arch Orthop Trauma Surg. 2018 Jan;138(1):73-82. doi: 10.1007/s00402-017-2811-y. Epub 2017 Oct 30.


Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.

Ferreira RMM, Sancho R, Messal HA, Nye E, Spencer-Dene B, Stone RK, Stamp G, Rosewell I, Quaglia A, Behrens A.

Cell Rep. 2017 Oct 24;21(4):966-978. doi: 10.1016/j.celrep.2017.09.093.


Learning outcomes evaluation of a simulation-based introductory course to anaesthesia.

Rábago JL, López-Doueil M, Sancho R, Hernández-Pinto P, Neira N, Capa E, Larraz E, Redondo-Figuero CG, Maestre JM.

Rev Esp Anestesiol Reanim. 2017 Oct;64(8):431-440. doi: 10.1016/j.redar.2016.12.008. Epub 2017 Mar 25. English, Spanish.


Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways.

Olmedo DA, López-Pérez JL, Del Olmo E, Bedoya LM, Sancho R, Alcamí J, Muñoz E, Feliciano AS, Gupta MP.

Molecules. 2017 Feb 19;22(2). pii: E321. doi: 10.3390/molecules22020321.


Survival of hydroxyapatite-coated cups: acetabular screws involve a lower rate of revision surgery due to aseptic loosening.

Natera L, Valera M, Gómez EM, Ibañez N, Crusi X, Sancho R.

Hip Int. 2017 Mar 31;27(2):153-161. doi: 10.5301/hipint.5000435. Epub 2017 Jan 28.


Towards the implementation of OSCE in undergraduate nursing curriculum: A qualitative study.

Solà M, Pulpón AM, Morin V, Sancho R, Clèries X, Fabrellas N.

Nurse Educ Today. 2017 Feb;49:163-167. doi: 10.1016/j.nedt.2016.11.028. Epub 2016 Dec 7.


Guidelines to improve animal study design and reproducibility for Alzheimer's disease and related dementias: For funders and researchers.

Snyder HM, Shineman DW, Friedman LG, Hendrix JA, Khachaturian A, Le Guillou I, Pickett J, Refolo L, Sancho RM, Ridley SH.

Alzheimers Dement. 2016 Nov;12(11):1177-1185. doi: 10.1016/j.jalz.2016.07.001.


The future of dementia risk reduction research: barriers and solutions.

Mitchell S, Ridley SH, Sancho RM, Norton M.

J Public Health (Oxf). 2017 Dec 1;39(4):e275-e281. doi: 10.1093/pubmed/fdw103.


Alzheimer's Research UK 2016 Conference report.

Sancho RM, Cox CJ, Phipps LE, Ridley SH.

Alzheimers Res Ther. 2016 Sep 15;8(1):35. doi: 10.1186/s13195-016-0203-0. Review.


ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.

Stoica R, Paillusson S, Gomez-Suaga P, Mitchell JC, Lau DH, Gray EH, Sancho RM, Vizcay-Barrena G, De Vos KJ, Shaw CE, Hanger DP, Noble W, Miller CC.

EMBO Rep. 2016 Sep;17(9):1326-42. doi: 10.15252/embr.201541726. Epub 2016 Jul 14.


Reliability of Tönnis classification in early hip arthritis: a useless reference for hip-preserving surgery.

Valera M, Ibañez N, Sancho R, Tey M.

Arch Orthop Trauma Surg. 2016 Jan;136(1):27-33. doi: 10.1007/s00402-015-2356-x. Epub 2015 Nov 14.


Fbw7 and its counteracting forces in stem cells and cancer: Oncoproteins in the balance.

Cremona CA, Sancho R, Diefenbacher ME, Behrens A.

Semin Cancer Biol. 2016 Feb;36:52-61. doi: 10.1016/j.semcancer.2015.09.006. Epub 2015 Sep 26. Review.


Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease.

Sancho R, Cremona CA, Behrens A.

EMBO Rep. 2015 May;16(5):571-81. doi: 10.15252/embr.201540188. Epub 2015 Apr 8. Review.


Report from the Alzheimer's Research UK Conference 2015.

Sancho RM, Cox CJ, Ridley SH, Phipps LE, Karran E.

Alzheimers Res Ther. 2015 Jul 28;7(1):52. doi: 10.1186/s13195-015-0138-x.


Highly expressed captured genes and cross-kingdom domains present in Helitrons create novel diversity in Pleurotus ostreatus and other fungi.

Castanera R, Pérez G, López L, Sancho R, Santoyo F, Alfaro M, Gabaldón T, Pisabarro AG, Oguiza JA, Ramírez L.

BMC Genomics. 2014 Dec 5;15:1071. doi: 10.1186/1471-2164-15-1071.


Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations.

Godena VK, Brookes-Hocking N, Moller A, Shaw G, Oswald M, Sancho RM, Miller CC, Whitworth AJ, De Vos KJ.

Nat Commun. 2014 Oct 15;5:5245. doi: 10.1038/ncomms6245.


Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells.

Sancho R, Gruber R, Gu G, Behrens A.

Cell Stem Cell. 2014 Aug 7;15(2):139-53. doi: 10.1016/j.stem.2014.06.019.


Monolithic silica columns functionalized with substituted polyproline-derived chiral selectors as chiral stationary phases for high-performance liquid chromatography.

Sancho R, Novell A, Svec F, Minguillón C.

J Sep Sci. 2014 Oct;37(20):2805-13. doi: 10.1002/jssc.201400640. Epub 2014 Sep 10.


ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.

Stoica R, De Vos KJ, Paillusson S, Mueller S, Sancho RM, Lau KF, Vizcay-Barrena G, Lin WL, Xu YF, Lewis J, Dickson DW, Petrucelli L, Mitchell JC, Shaw CE, Miller CC.

Nat Commun. 2014 Jun 3;5:3996. doi: 10.1038/ncomms4996.


Influenza vaccine effectiveness in Spain 2013/14: subtype-specific early estimates using the cycEVA study.

Jimenez-Jorge S, Pozo F, de Mateo S, Delgado-Sanz C, Casas I, Garcia-Cenoz M, Castilla J, Sancho R, Etxebarriarteun-Aranzabal L, Quinones C, Martinez E, Vega T, Garcia A, Gimenez J, Vanrell JM, Castrillejo D, Larrauri A; Spanish Influenza Sentinel Surveillance System (SISS).

Euro Surveill. 2014 Mar 6;19(9). pii: 20727.


A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation.

Law BM, Spain VA, Leinster VH, Chia R, Beilina A, Cho HJ, Taymans JM, Urban MK, Sancho RM, Blanca Ramírez M, Biskup S, Baekelandt V, Cai H, Cookson MR, Berwick DC, Harvey K.

J Biol Chem. 2014 Jan 10;289(2):895-908. doi: 10.1074/jbc.M113.507913. Epub 2013 Nov 25.


[Curricular design in anesthesiology using clinical simulation as a teaching tool].

Maestre JM, Sancho R, Rábago JL, Del Moral I.

Rev Esp Anestesiol Reanim. 2014 Jan;61(1):55-6. doi: 10.1016/j.redar.2013.07.010. Epub 2013 Oct 19. Spanish. No abstract available.


Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions.

Sancho R, Blake SM, Tendeng C, Clurman BE, Lewis J, Behrens A.

PLoS Biol. 2013;11(6):e1001586. doi: 10.1371/journal.pbio.1001586. Epub 2013 Jun 11.


Facile two-electron reduction of a closo-rhodathiadecaborane.

Luaces S, Bould J, Macías R, Sancho R, Lahoz FJ, Oro LA.

Dalton Trans. 2012 Oct 14;41(38):11627-34. doi: 10.1039/c2dt31465g. Epub 2012 Aug 23.


3-Phenylcoumarins as inhibitors of HIV-1 replication.

Olmedo D, Sancho R, Bedoya LM, López-Pérez JL, Del Olmo E, Muñoz E, Alcamí J, Gupta MP, San Feliciano A.

Molecules. 2012 Aug 2;17(8):9245-57. doi: 10.3390/molecules17089245.


Ligand-controlled regioselectivity in the hydrothiolation of alkynes by rhodium N-heterocyclic carbene catalysts.

Di Giuseppe A, Castarlenas R, Pérez-Torrente JJ, Crucianelli M, Polo V, Sancho R, Lahoz FJ, Oro LA.

J Am Chem Soc. 2012 May 16;134(19):8171-83. doi: 10.1021/ja300396h. Epub 2012 May 3.


Effect of annatto seed and coriander leaves as natural antioxidants in fish meatballs during frozen storage.

Sancho RA, de Lima FA, Costa GG, Mariutti LR, Bragagnolo N.

J Food Sci. 2011 Aug;76(6):C838-45. doi: 10.1111/j.1750-3841.2011.02224.x. Epub 2011 Jun 8.


Vanilloid receptor-1 regulates neurogenic inflammation in colon and protects mice from colon cancer.

Vinuesa AG, Sancho R, García-Limones C, Behrens A, ten Dijke P, Calzado MA, Muñoz E.

Cancer Res. 2012 Apr 1;72(7):1705-16. doi: 10.1158/0008-5472.CAN-11-3693. Epub 2012 Mar 6.


[Bringing clinical simulation into anesthesiology and postoperative recovery care residency training].

Sancho R, Rábago JL, Maestre JM, Del Moral I, Carceller JM.

Rev Esp Anestesiol Reanim. 2010 Dec;57(10):656-63. Spanish.


The F-box protein Fbw7 is required for cerebellar development.

Jandke A, Da Costa C, Sancho R, Nye E, Spencer-Dene B, Behrens A.

Dev Biol. 2011 Oct 1;358(1):201-12. doi: 10.1016/j.ydbio.2011.07.030. Epub 2011 Jul 29.


ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma.

Loizou JI, Sancho R, Kanu N, Bolland DJ, Yang F, Rada C, Corcoran AE, Behrens A.

Cancer Cell. 2011 May 17;19(5):587-600. doi: 10.1016/j.ccr.2011.03.022.


[Effectiveness assessment of public clinical laboratories: the case of Belo Horizonte, Minas Gerais State].

Sancho LG, Vargens JM, Sancho RG.

Cien Saude Colet. 2011;16 Suppl 1:1135-44. Portuguese.


c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex.

Aguilera C, Nakagawa K, Sancho R, Chakraborty A, Hendrich B, Behrens A.

Nature. 2011 Jan 13;469(7329):231-5. doi: 10.1038/nature09607. Epub 2011 Jan 2.


F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.

Sancho R, Jandke A, Davis H, Diefenbacher ME, Tomlinson I, Behrens A.

Gastroenterology. 2010 Sep;139(3):929-41. doi: 10.1053/j.gastro.2010.05.078. Epub 2010 Jun 2.


Bag1-L is a phosphorylation-dependent coactivator of c-Jun during neuronal apoptosis.

Da Costa CR, Villadiego J, Sancho R, Fontana X, Packham G, Nateri AS, Behrens A.

Mol Cell Biol. 2010 Aug;30(15):3842-52. doi: 10.1128/MCB.01610-09. Epub 2010 Jun 1.


[Characterization of tuberculosis cases in the foreign- and native-born population in Guipúzcoa (Spain) from 2003-2007].

Basterrechea M, Sancho R, Idígoras P, Temprano YM; por el Grupo de seguimiento del programa de prevención y control de la tuberculosis en Guipúzcoa.

Gac Sanit. 2009 Dec;23 Suppl 1:74-9. doi: 10.1016/j.gaceta.2009.09.009. Epub 2009 Nov 25. Spanish.


Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways.

Sancho RM, Law BM, Harvey K.

Hum Mol Genet. 2009 Oct 15;18(20):3955-68. doi: 10.1093/hmg/ddp337. Epub 2009 Jul 22.


JNK signalling modulates intestinal homeostasis and tumourigenesis in mice.

Sancho R, Nateri AS, de Vinuesa AG, Aguilera C, Nye E, Spencer-Dene B, Behrens A.

EMBO J. 2009 Jul 8;28(13):1843-54. doi: 10.1038/emboj.2009.153. Epub 2009 Jun 11.


The chromatographic separation of enantiomers through nanoscale design.

Sancho R, Minguillón C.

Chem Soc Rev. 2009 Mar;38(3):797-805. doi: 10.1039/b718359n. Epub 2009 Jan 13. Review.


Adducts of the supraicosahedral stannacarborane 1,6-Me2-4,1,6-closo-SnC2B10H10; synthetic, structural and computational studies.

Abram PD, McKay D, Ellis D, Macgregor SA, Rosair GM, Sancho R, Welch AJ.

Dalton Trans. 2009 Apr 7;(13):2345-51. doi: 10.1039/b821417d. Epub 2009 Feb 18.


Selective monosulfoxidation of tetrathiafulvalenes into chiral TTF-sulfoxides.

Chas M, Riobé F, Sancho R, Minguíllon C, Avarvari N.

Chirality. 2009 Oct;21(9):818-25. doi: 10.1002/chir.20692.


In vitro anti-HIV-1 properties of ethnobotanically selected South African plants used in the treatment of sexually transmitted diseases.

Tshikalange TE, Meyer JJ, Lall N, Muñoz E, Sancho R, Van de Venter M, Oosthuizen V.

J Ethnopharmacol. 2008 Oct 28;119(3):478-81. doi: 10.1016/j.jep.2008.08.027. Epub 2008 Sep 2.


Polyproline derivatives as chiral selectors in high performance liquid chromatography: chromatographic and conformational studies.

Sancho R, Minguillón C.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Nov 1;875(1):93-101. doi: 10.1016/j.jchromb.2008.05.041.


The acetaminophen-derived bioactive N-acylphenolamine AM404 inhibits NFAT by targeting nuclear regulatory events.

Caballero FJ, Navarrete CM, Hess S, Fiebich BL, Appendino G, Macho A, Muñoz E, Sancho R.

Biochem Pharmacol. 2007 Apr 1;73(7):1013-23. Epub 2006 Dec 15.


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