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Items: 1 to 50 of 127

1.

Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection.

Saz-Leal P, Del Fresno C, Brandi P, Martínez-Cano S, Dungan OM, Chisholm JD, Kerr WG, Sancho D.

Cell Rep. 2018 Oct 30;25(5):1118-1126. doi: 10.1016/j.celrep.2018.09.092.

2.

DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment.

Del Fresno C, Saz-Leal P, Enamorado M, Wculek SK, Martínez-Cano S, Blanco-Menéndez N, Schulz O, Gallizioli M, Miró-Mur F, Cano E, Planas A, Sancho D.

Science. 2018 Oct 19;362(6412):351-356. doi: 10.1126/science.aan8423.

PMID:
30337411
3.

Intratumoral immunotherapy with XCL1 and sFlt3L encoded in recombinant Semliki Forest Virus-derived vectors fosters dendritic cell-mediated T cell cross-priming.

Sanchez-Paulete AR, Teijeira A, Quetglas JI, Rodriguez-Ruiz ME, Sanchez-Arraez A, Labiano S, Etxeberria I, Azpilikueta A, Bolaños E, Ballesteros-Briones MC, Casares N, Quezada SA, Berraondo P, Sancho D, Smerdou C, Melero I.

Cancer Res. 2018 Oct 8. pii: canres.0933.2018. doi: 10.1158/0008-5472.CAN-18-0933. [Epub ahead of print]

PMID:
30297531
4.

Instrumental Effects in the Dynamics of an Ultrafast Folding Protein under Mechanical Force.

De Sancho D, Schönfelder J, Best RB, Perez-Jimenez R, Muñoz V.

J Phys Chem B. 2018 Aug 21. doi: 10.1021/acs.jpcb.8b05975. [Epub ahead of print]

PMID:
30129367
5.

Von Hippel-Lindau Protein Is Required for Optimal Alveolar Macrophage Terminal Differentiation, Self-Renewal, and Function.

Izquierdo HM, Brandi P, Gómez MJ, Conde-Garrosa R, Priego E, Enamorado M, Martínez-Cano S, Sánchez I, Conejero L, Jimenez-Carretero D, Martín-Puig S, Guilliams M, Sancho D.

Cell Rep. 2018 Aug 14;24(7):1738-1746. doi: 10.1016/j.celrep.2018.07.034.

6.

Genealogy, Dendritic Cell Priming, and Differentiation of Tissue-Resident Memory CD8+ T Cells.

Enamorado M, Khouili SC, Iborra S, Sancho D.

Front Immunol. 2018 Jul 31;9:1751. doi: 10.3389/fimmu.2018.01751. eCollection 2018. Review.

7.

Mechanical architecture and folding of E. coli type 1 pilus domains.

Alonso-Caballero A, Schönfelder J, Poly S, Corsetti F, De Sancho D, Artacho E, Perez-Jimenez R.

Nat Commun. 2018 Jul 16;9(1):2758. doi: 10.1038/s41467-018-05107-6.

8.

MSM/RD: Coupling Markov state models of molecular kinetics with reaction-diffusion simulations.

Dibak M, Del Razo MJ, De Sancho D, Schütte C, Noé F.

J Chem Phys. 2018 Jun 7;148(21):214107. doi: 10.1063/1.5020294.

PMID:
29884049
9.

Leishmania Hijacks Myeloid Cells for Immune Escape.

Martínez-López M, Soto M, Iborra S, Sancho D.

Front Microbiol. 2018 May 7;9:883. doi: 10.3389/fmicb.2018.00883. eCollection 2018. Review.

10.

Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation.

Del Fresno C, Iborra S, Saz-Leal P, Martínez-López M, Sancho D.

Front Immunol. 2018 Apr 26;9:804. doi: 10.3389/fimmu.2018.00804. eCollection 2018. Review.

11.

IVIg Promote Cross-Tolerance against Inflammatory Stimuli In Vitro and In Vivo.

Domínguez-Soto Á, Simón-Fuentes M, de Las Casas-Engel M, Cuevas VD, López-Bravo M, Domínguez-Andrés J, Saz-Leal P, Sancho D, Ardavín C, Ochoa-Grullón J, Sánchez-Ramón S, Vega MA, Corbí AL.

J Immunol. 2018 Jul 1;201(1):41-52. doi: 10.4049/jimmunol.1701093. Epub 2018 May 9.

PMID:
29743313
12.

Flow Cytometry Data Preparation Guidelines for Improved Automated Phenotypic Analysis.

Jimenez-Carretero D, Ligos JM, Martínez-López M, Sancho D, Montoya MC.

J Immunol. 2018 May 15;200(10):3319-3331. doi: 10.4049/jimmunol.1800446.

PMID:
29735643
13.

Correction to Identification of Mutational Hot Spots for Substrate Diffusion: Application to Myoglobin.

De Sancho D, Kubas A, Wang PH, Blumberger J, Best RB.

J Chem Theory Comput. 2018 May 8;14(5):2822. doi: 10.1021/acs.jctc.8b00325. Epub 2018 Apr 30. No abstract available.

14.

Mitochondrial Morphological and Functional Reprogramming Following CD137 (4-1BB) Costimulation.

Teijeira A, Labiano S, Garasa S, Etxeberria I, Santamaría E, Rouzaut A, Enamorado M, Azpilikueta A, Inoges S, Bolaños E, Aznar MA, Sánchez-Paulete AR, Sancho D, Melero I.

Cancer Immunol Res. 2018 Jul;6(7):798-811. doi: 10.1158/2326-6066.CIR-17-0767. Epub 2018 Apr 20.

PMID:
29678874
15.

Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.

Kaisar MMM, Ritter M, Del Fresno C, Jónasdóttir HS, van der Ham AJ, Pelgrom LR, Schramm G, Layland LE, Sancho D, Prazeres da Costa C, Giera M, Yazdanbakhsh M, Everts B.

PLoS Biol. 2018 Apr 18;16(4):e2005504. doi: 10.1371/journal.pbio.2005504. eCollection 2018 Apr.

16.

The life of proteins under mechanical force.

Schönfelder J, Alonso-Caballero A, De Sancho D, Perez-Jimenez R.

Chem Soc Rev. 2018 May 21;47(10):3558-3573. doi: 10.1039/c7cs00820a. Review.

PMID:
29473060
17.

Correction: Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity.

Alloatti A, Rookhuizen DC, Joannas L, Carpier JM, Iborra S, Magalhaes JG, Yatim N, Kozik P, Sancho D, Albert ML, Amigorena S.

J Exp Med. 2018 Mar 5;215(3):1001. doi: 10.1084/jem.2017022902092018c. Epub 2018 Feb 15. No abstract available.

18.

Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming.

van Dinther D, Veninga H, Iborra S, Borg EGF, Hoogterp L, Olesek K, Beijer MR, Schetters STT, Kalay H, Garcia-Vallejo JJ, Franken KL, Cham LB, Lang KS, van Kooyk Y, Sancho D, Crocker PR, den Haan JMM.

Cell Rep. 2018 Feb 6;22(6):1484-1495. doi: 10.1016/j.celrep.2018.01.021.

19.

Lamin A/C augments Th1 differentiation and response against vaccinia virus and Leishmania major.

Toribio-Fernández R, Zorita V, Rocha-Perugini V, Iborra S, Martínez Del Hoyo G, Chevre R, Dorado B, Sancho D, Sanchez-Madrid F, Andrés V, Gonzalez-Granado JM.

Cell Death Dis. 2018 Jan 8;9(1):9. doi: 10.1038/s41419-017-0007-6.

20.

Antigen cross-presentation and T-cell cross-priming in cancer immunology and immunotherapy.

Sánchez-Paulete AR, Teijeira A, Cueto FJ, Garasa S, Pérez-Gracia JL, Sánchez-Arráez A, Sancho D, Melero I.

Ann Oncol. 2017 Dec 1;28(suppl_12):xii74. doi: 10.1093/annonc/mdx727. No abstract available.

PMID:
29253116
21.

Interplay between the folding mechanism and binding modes in folding coupled to binding processes.

Sharma R, De Sancho D, Muñoz V.

Phys Chem Chem Phys. 2017 Nov 1;19(42):28512-28516. doi: 10.1039/c7cp04748g.

PMID:
29044256
22.

Antigen cross-presentation and T-cell cross-priming in cancer immunology and immunotherapy.

Sánchez-Paulete AR, Teijeira A, Cueto FJ, Garasa S, Pérez-Gracia JL, Sánchez-Arráez A, Sancho D, Melero I.

Ann Oncol. 2017 Dec 1;28(suppl_12):xii44-xii55. doi: 10.1093/annonc/mdx237. Erratum in: Ann Oncol. 2017 Dec 1;28(suppl_12):xii74.

PMID:
28945841
23.

Human dendritic cells activated with MV130 induce Th1, Th17 and IL-10 responses via RIPK2 and MyD88 signalling pathways.

Cirauqui C, Benito-Villalvilla C, Sánchez-Ramón S, Sirvent S, Diez-Rivero CM, Conejero L, Brandi P, Hernández-Cillero L, Ochoa JL, Pérez-Villamil B, Sancho D, Subiza JL, Palomares O.

Eur J Immunol. 2018 Jan;48(1):180-193. doi: 10.1002/eji.201747024. Epub 2017 Sep 14.

24.

Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells.

Enamorado M, Iborra S, Priego E, Cueto FJ, Quintana JA, Martínez-Cano S, Mejías-Pérez E, Esteban M, Melero I, Hidalgo A, Sancho D.

Nat Commun. 2017 Jul 17;8:16073. doi: 10.1038/ncomms16073.

25.

Mechanochemical evolution of the giant muscle protein titin as inferred from resurrected proteins.

Manteca A, Schönfelder J, Alonso-Caballero A, Fertin MJ, Barruetabeña N, Faria BF, Herrero-Galán E, Alegre-Cebollada J, De Sancho D, Perez-Jimenez R.

Nat Struct Mol Biol. 2017 Aug;24(8):652-657. doi: 10.1038/nsmb.3426. Epub 2017 Jul 3.

PMID:
28671667
26.

Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity.

Alloatti A, Rookhuizen DC, Joannas L, Carpier JM, Iborra S, Magalhaes JG, Yatim N, Kozik P, Sancho D, Albert ML, Amigorena S.

J Exp Med. 2017 Aug 7;214(8):2231-2241. doi: 10.1084/jem.20170229. Epub 2017 Jun 29. Erratum in: J Exp Med. 2018 Feb 15;:.

27.

The influence of disulfide bonds on the mechanical stability of proteins is context dependent.

Manteca A, Alonso-Caballero Á, Fertin M, Poly S, De Sancho D, Perez-Jimenez R.

J Biol Chem. 2017 Aug 11;292(32):13374-13380. doi: 10.1074/jbc.M117.784934. Epub 2017 Jun 22.

28.

Innate Immune Function of Mitochondrial Metabolism.

Sancho D, Enamorado M, Garaude J.

Front Immunol. 2017 May 8;8:527. doi: 10.3389/fimmu.2017.00527. eCollection 2017. Review.

29.

Lung CD103+ dendritic cells restrain allergic airway inflammation through IL-12 production.

Conejero L, Khouili SC, Martínez-Cano S, Izquierdo HM, Brandi P, Sancho D.

JCI Insight. 2017 May 18;2(10). pii: 90420. doi: 10.1172/jci.insight.90420. [Epub ahead of print]

30.

Rational design of adjuvants targeting the C-type lectin Mincle.

Decout A, Silva-Gomes S, Drocourt D, Barbe S, André I, Cueto FJ, Lioux T, Sancho D, Pérouzel E, Vercellone A, Prandi J, Gilleron M, Tiraby G, Nigou J.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2675-2680. doi: 10.1073/pnas.1612421114. Epub 2017 Feb 21.

31.

Mechanism of O2 diffusion and reduction in FeFe hydrogenases.

Kubas A, Orain C, De Sancho D, Saujet L, Sensi M, Gauquelin C, Meynial-Salles I, Soucaille P, Bottin H, Baffert C, Fourmond V, Best RB, Blumberger J, Léger C.

Nat Chem. 2017 Jan;9(1):88-95. doi: 10.1038/nchem.2592. Epub 2016 Aug 22.

32.

Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection.

Iborra S, Martínez-López M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Izquierdo HM, Abram CL, Mori D, Campos-Martín Y, Reguera RM, Kemp B, Yamasaki S, Robinson MJ, Soto M, Lowell CA, Sancho D.

Immunity. 2016 Oct 18;45(4):788-801. doi: 10.1016/j.immuni.2016.09.012. Epub 2016 Oct 11.

33.

Optimal Generation of Tissue-Resident but Not Circulating Memory T Cells during Viral Infection Requires Crosspriming by DNGR-1+ Dendritic Cells.

Iborra S, Martínez-López M, Khouili SC, Enamorado M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Sancho D.

Immunity. 2016 Oct 18;45(4):847-860. doi: 10.1016/j.immuni.2016.08.019. Epub 2016 Sep 27.

34.

Design and realization of transparent solar modules based on luminescent solar concentrators integrating nanostructured photonic crystals.

Jiménez-Solano A, Delgado-Sánchez JM, Calvo ME, Miranda-Muñoz JM, Lozano G, Sancho D, Sánchez-Cortezón E, Míguez H.

Prog Photovolt. 2015 Dec;23(12):1785-1792. Epub 2015 Apr 23.

35.

The Power of Force: Insights into the Protein Folding Process Using Single-Molecule Force Spectroscopy.

Schönfelder J, De Sancho D, Perez-Jimenez R.

J Mol Biol. 2016 Oct 23;428(21):4245-4257. doi: 10.1016/j.jmb.2016.09.006. Epub 2016 Sep 14. Review.

PMID:
27639437
36.

Reconciling Intermediates in Mechanical Unfolding Experiments with Two-State Protein Folding in Bulk.

de Sancho D, Best RB.

J Phys Chem Lett. 2016 Oct 6;7(19):3798-3803. Epub 2016 Sep 14.

37.

Computation of Rate Constants for Diffusion of Small Ligands to and from Buried Protein Active Sites.

Wang PH, De Sancho D, Best RB, Blumberger J.

Methods Enzymol. 2016;578:299-326. doi: 10.1016/bs.mie.2016.05.039. Epub 2016 Jun 27. Review.

PMID:
27497172
38.

Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense.

Garaude J, Acín-Pérez R, Martínez-Cano S, Enamorado M, Ugolini M, Nistal-Villán E, Hervás-Stubbs S, Pelegrín P, Sander LE, Enríquez JA, Sancho D.

Nat Immunol. 2016 Sep;17(9):1037-1045. doi: 10.1038/ni.3509. Epub 2016 Jun 27.

39.

Modulation of Folding Internal Friction by Local and Global Barrier Heights.

Zheng W, de Sancho D, Best RB.

J Phys Chem Lett. 2016 Mar 17;7(6):1028-34. doi: 10.1021/acs.jpclett.6b00329. Epub 2016 Mar 7.

40.

Multifrequency Force Microscopy of Helical Protein Assembly on a Virus.

Calò A, Eleta-Lopez A, Stoliar P, De Sancho D, Santos S, Verdaguer A, Bittner AM.

Sci Rep. 2016 Feb 26;6:21899. doi: 10.1038/srep21899.

41.

Markov state models of protein misfolding.

Sirur A, De Sancho D, Best RB.

J Chem Phys. 2016 Feb 21;144(7):075101. doi: 10.1063/1.4941579.

42.

HDAC6 regulates the dynamics of lytic granules in cytotoxic T lymphocytes.

Núñez-Andrade N, Iborra S, Trullo A, Moreno-Gonzalo O, Calvo E, Catalán E, Menasche G, Sancho D, Vázquez J, Yao TP, Martín-Cófreces NB, Sánchez-Madrid F.

J Cell Sci. 2016 Apr 1;129(7):1305-1311. doi: 10.1242/jcs.180885. Epub 2016 Feb 11.

43.

Identification of Mutational Hot Spots for Substrate Diffusion: Application to Myoglobin.

De Sancho D, Kubas A, Wang PH, Blumberger J, Best RB.

J Chem Theory Comput. 2015 Apr 14;11(4):1919-27. doi: 10.1021/ct5011455. Erratum in: J Chem Theory Comput. 2018 May 8;14 (5):2822.

44.

Bridging Experiments and Native-Centric Simulations of a Downhill Folding Protein.

Naganathan AN, De Sancho D.

J Phys Chem B. 2015 Nov 25;119(47):14925-33. doi: 10.1021/acs.jpcb.5b09568. Epub 2015 Nov 16.

PMID:
26524123
45.

Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells.

Sánchez-Paulete AR, Cueto FJ, Martínez-López M, Labiano S, Morales-Kastresana A, Rodríguez-Ruiz ME, Jure-Kunkel M, Azpilikueta A, Aznar MA, Quetglas JI, Sancho D, Melero I.

Cancer Discov. 2016 Jan;6(1):71-9. doi: 10.1158/2159-8290.CD-15-0510. Epub 2015 Oct 22.

46.

SHIP-1 Couples to the Dectin-1 hemITAM and Selectively Modulates Reactive Oxygen Species Production in Dendritic Cells in Response to Candida albicans.

Blanco-Menéndez N, Del Fresno C, Fernandes S, Calvo E, Conde-Garrosa R, Kerr WG, Sancho D.

J Immunol. 2015 Nov 1;195(9):4466-4478. doi: 10.4049/jimmunol.1402874. Epub 2015 Sep 28.

47.

Dementia and Caregiver Stress: An Application of the Reconceptualized Uncertainty in Illness Theory.

Unson C, Flynn D, Glendon MA, Haymes E, Sancho D.

Issues Ment Health Nurs. 2015 Jun;36(6):439-46.

PMID:
26241570
48.

DNGR-1(+) dendritic cells are located in meningeal membrane and choroid plexus of the noninjured brain.

Quintana E, Fernández A, Velasco P, de Andrés B, Liste I, Sancho D, Gaspar ML, Cano E.

Glia. 2015 Dec;63(12):2231-48. doi: 10.1002/glia.22889. Epub 2015 Jul 17.

PMID:
26184558
49.

Spanish Immunology on the move.

Sancho D, Villar LM, Regueiro JR, de Andrés B.

Eur J Immunol. 2015 Jun;45(6):1580-3. doi: 10.1002/eji.201570064. No abstract available.

50.

Efficient T-cell priming and activation requires signaling through prostaglandin E2 (EP) receptors.

Sreeramkumar V, Hons M, Punzón C, Stein JV, Sancho D, Fresno M, Cuesta N.

Immunol Cell Biol. 2016 Jan;94(1):39-51. doi: 10.1038/icb.2015.62. Epub 2015 Jun 8.

PMID:
26051593

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