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Items: 1 to 50 of 57

1.

Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue.

Torres P, Ramírez-Núñez O, Romero-Guevara R, Barés G, Granado-Serrano AB, Ayala V, Boada J, Fontdevila L, Povedano M, Sanchís D, Pamplona R, Ferrer I, Portero-Otín M.

Autophagy. 2018;14(8):1398-1403. doi: 10.1080/15548627.2018.1474311. Epub 2018 Jul 28.

PMID:
29912613
2.

Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin.

Blasco N, Cámara Y, Núñez E, Beà A, Barés G, Forné C, Ruíz-Meana M, Girón C, Barba I, García-Arumí E, García-Dorado D, Vázquez J, Martí R, Llovera M, Sanchis D.

Redox Biol. 2018 Jun;16:146-156. doi: 10.1016/j.redox.2018.02.021. Epub 2018 Mar 1.

3.

Deletion of protein kinase B2 preserves cardiac function by blocking interleukin-6-mediated injury and restores blood pressure during angiotensin II/high-salt-diet-induced hypertension.

Yang S, Chen D, Chen F, Zhao X, Zhang Y, Li Z, Jin L, Xu Y, Sanchis D, Ye J.

J Hypertens. 2018 Apr;36(4):834-846. doi: 10.1097/HJH.0000000000001613.

PMID:
29120957
4.

Interleukin-6 deficiency facilitates myocardial dysfunction during high fat diet-induced obesity by promoting lipotoxicity and inflammation.

Chen F, Chen D, Zhao X, Yang S, Li Z, Sanchis D, Jin L, Qiang X, Wang K, Xu Y, Zhang Y, Ye J.

Biochim Biophys Acta Mol Basis Dis. 2017 Dec;1863(12):3128-3141. doi: 10.1016/j.bbadis.2017.08.022. Epub 2017 Aug 24.

PMID:
28844956
5.

AKT2 Blocks Nucleus Translocation of Apoptosis-Inducing Factor (AIF) and Endonuclease G (EndoG) While Promoting Caspase Activation during Cardiac Ischemia.

Yang S, Zhao X, Xu H, Chen F, Xu Y, Li Z, Sanchis D, Jin L, Zhang Y, Ye J.

Int J Mol Sci. 2017 Mar 6;18(3). pii: E565. doi: 10.3390/ijms18030565.

6.

EndoG Knockout Mice Show Increased Brown Adipocyte Recruitment in White Adipose Tissue and Improved Glucose Homeostasis.

Pardo R, Blasco N, Vilà M, Beiroa D, Nogueiras R, Cañas X, Simó R, Sanchis D, Villena JA.

Endocrinology. 2016 Oct;157(10):3873-3887. Epub 2016 Aug 22.

PMID:
27547848
7.

Studies on the role of apoptosis after transient myocardial ischemia: genetic deletion of the executioner caspases-3 and -7 does not limit infarct size and ventricular remodeling.

Inserte J, Cardona M, Poncelas-Nozal M, Hernando V, Vilardosa Ú, Aluja D, Parra VM, Sanchis D, Garcia-Dorado D.

Basic Res Cardiol. 2016 Mar;111(2):18. doi: 10.1007/s00395-016-0537-6. Epub 2016 Feb 16.

PMID:
26924441
8.

Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart.

Cardona M, López JA, Serafín A, Rongvaux A, Inserte J, García-Dorado D, Flavell R, Llovera M, Cañas X, Vázquez J, Sanchis D.

PLoS One. 2015 Jun 29;10(6):e0131411. doi: 10.1371/journal.pone.0131411. eCollection 2015.

9.

Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe.

Cornago M, Garcia-Alberich C, Blasco-Angulo N, Vall-Llaura N, Nager M, Herreros J, Comella JX, Sanchis D, Llovera M.

Cell Death Dis. 2014 Oct 2;5:e1435. doi: 10.1038/cddis.2014.412.

10.

Frataxin deficiency in neonatal rat ventricular myocytes targets mitochondria and lipid metabolism.

Obis È, Irazusta V, Sanchís D, Ros J, Tamarit J.

Free Radic Biol Med. 2014 Aug;73:21-33. doi: 10.1016/j.freeradbiomed.2014.04.016. Epub 2014 Apr 18.

PMID:
24751525
11.

FAIM-L is an IAP-binding protein that inhibits XIAP ubiquitinylation and protects from Fas-induced apoptosis.

Moubarak RS, Planells-Ferrer L, Urresti J, Reix S, Segura MF, Carriba P, Marqués-Fernàndez F, Sole C, Llecha-Cano N, Lopez-Soriano J, Sanchis D, Yuste VJ, Comella JX.

J Neurosci. 2013 Dec 4;33(49):19262-75. doi: 10.1523/JNEUROSCI.2479-13.2013.

12.

Neurobehavioral characterization of Endonuclease G knockout mice reveals a new putative molecular player in the regulation of anxiety.

Giralt A, Sanchis D, Cherubini M, Ginés S, Cañas X, Comella JX, Alberch J.

Exp Neurol. 2013 Sep;247:122-9. doi: 10.1016/j.expneurol.2013.03.028. Epub 2013 Apr 18.

PMID:
23603365
13.

A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart.

Ye J, Llorian M, Cardona M, Rongvaux A, Moubarak RS, Comella JX, Bassel-Duby R, Flavell RA, Olson EN, Smith CW, Sanchis D.

J Cell Sci. 2013 Apr 1;126(Pt 7):1682-91. doi: 10.1242/jcs.121384. Epub 2013 Feb 19.

14.

Towards germline gene therapy of inherited mitochondrial diseases.

Tachibana M, Amato P, Sparman M, Woodward J, Sanchis DM, Ma H, Gutierrez NM, Tippner-Hedges R, Kang E, Lee HS, Ramsey C, Masterson K, Battaglia D, Lee D, Wu D, Jensen J, Patton P, Gokhale S, Stouffer R, Mitalipov S.

Nature. 2013 Jan 31;493(7434):627-31. doi: 10.1038/nature11647. Epub 2012 Oct 24.

15.

Translation of Myocyte Enhancer Factor-2 is induced by hypertrophic stimuli in cardiomyocytes through a Calcineurin-dependent pathway.

Ye J, Cardona M, Llovera M, Comella JX, Sanchis D.

J Mol Cell Cardiol. 2012 Oct;53(4):578-87. doi: 10.1016/j.yjmcc.2012.07.013. Epub 2012 Jul 28.

PMID:
22850285
16.

Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.

McDermott-Roe C, Ye J, Ahmed R, Sun XM, Serafín A, Ware J, Bottolo L, Muckett P, Cañas X, Zhang J, Rowe GC, Buchan R, Lu H, Braithwaite A, Mancini M, Hauton D, Martí R, García-Arumí E, Hubner N, Jacob H, Serikawa T, Zidek V, Papousek F, Kolar F, Cardona M, Ruiz-Meana M, García-Dorado D, Comella JX, Felkin LE, Barton PJ, Arany Z, Pravenec M, Petretto E, Sanchis D, Cook SA.

Nature. 2011 Oct 5;478(7367):114-8. doi: 10.1038/nature10490.

17.

EndoG links Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes.

Zhang J, Ye J, Altafaj A, Cardona M, Bahi N, Llovera M, Cañas X, Cook SA, Comella JX, Sanchis D.

PLoS One. 2011 Mar 17;6(3):e17998. doi: 10.1371/journal.pone.0017998.

18.

Ubiquitination of TrkA by Nedd4-2 regulates receptor lysosomal targeting and mediates receptor signaling.

Georgieva MV, de Pablo Y, Sanchis D, Comella JX, Llovera M.

J Neurochem. 2011 May;117(3):479-93. doi: 10.1111/j.1471-4159.2011.07218.x. Epub 2011 Mar 15.

19.

Polypyrimidine tract binding proteins (PTB) regulate the expression of apoptotic genes and susceptibility to caspase-dependent apoptosis in differentiating cardiomyocytes.

Zhang J, Bahi N, Llovera M, Comella JX, Sanchis D.

Cell Death Differ. 2009 Nov;16(11):1460-8. doi: 10.1038/cdd.2009.87. Epub 2009 Jul 10.

20.

BCL-XL regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs.

Gozzelino R, Sole C, Llecha N, Segura MF, Moubarak RS, Iglesias-Guimarais V, Perez-Garcia MJ, Reix S, Zhang J, Badiola N, Sanchis D, Rodriguez-Alvarez J, Trullas R, Yuste VJ, Comella JX.

Cell Res. 2008 Oct;18(10):1020-36. doi: 10.1038/cr.2008.76.

PMID:
18591962
22.

Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function.

de Pablo Y, Pérez-García MJ, Georgieva MV, Sanchis D, Lindqvist N, Soler RM, Comella JX, Llovera M.

J Neurochem. 2008 Jan;104(1):124-39. doi: 10.1111/j.1471-4159.2007.05027.x.

23.

Developmental silencing and independency from E2F of apoptotic gene expression in postmitotic tissues.

Zhang J, Bahi N, Zubiaga AM, Comella JX, Llovera M, Sanchis D.

FEBS Lett. 2007 Dec 22;581(30):5781-6. Epub 2007 Nov 26.

24.

An alternative view of apoptosis in heart development and disease.

Sanchis D, Llovera M, Ballester M, Comella JX.

Cardiovasc Res. 2008 Feb 1;77(3):448-51. Epub 2007 Nov 20. No abstract available.

PMID:
18032394
25.

Induction of Ucp2 expression in brain phagocytes and neurons following murine toxoplasmosis: an essential role of IFN-gamma and an association with negative energy balance.

Arsenijevic D, Clavel S, Sanchis D, Plamondon J, Huang Q, Ricquier D, Rouger L, Richard D.

J Neuroimmunol. 2007 May;186(1-2):121-32. Epub 2007 Apr 30.

PMID:
17467814
26.
27.

Pacemaker lead infection caused by Aspergillus fumigatus.

Marchena Yglesias PJ, Rodríguez JA, García GA, Sanchís DV, Muños NS, Nuñez JF.

Eur J Intern Med. 2006 May;17(3):209-10.

PMID:
16618457
28.

Antiproliferative effect of STI571 on cultured human cutaneous melanoma-derived cell lines.

Mayorga ME, Sanchis D, Perez de Santos AM, Velasco A, Dolcet X, Casanova JM, Baradad M, Egido R, Pallares J, Espurz N, Benitez D, Mila J, Malvehy J, Castel T, Comella JX, Matias-Guiu X, Vilella R, Marti RM.

Melanoma Res. 2006 Apr;16(2):127-35.

PMID:
16567968
29.

Pancreatic carcinoma and basal cell carcinoma secondary to Hodgkin's disease treatment.

Sanchis DV, Garcia GA, Moya OB.

Eur J Intern Med. 2005 Feb;16(1):64. No abstract available.

PMID:
15733828
30.

The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signaling.

Sole C, Dolcet X, Segura MF, Gutierrez H, Diaz-Meco MT, Gozzelino R, Sanchis D, Bayascas JR, Gallego C, Moscat J, Davies AM, Comella JX.

J Cell Biol. 2004 Nov 8;167(3):479-92. Epub 2004 Nov 1.

31.

Bcl-2 is a key factor for cardiac fibroblast resistance to programmed cell death.

Mayorga M, Bahi N, Ballester M, Comella JX, Sanchis D.

J Biol Chem. 2004 Aug 13;279(33):34882-9. Epub 2004 Jun 7.

32.

Lack of Apaf-1 expression confers resistance to cytochrome c-driven apoptosis in cardiomyocytes.

Sanchis D, Mayorga M, Ballester M, Comella JX.

Cell Death Differ. 2003 Sep;10(9):977-86.

33.

Uncoupling protein 2 in the brain: distribution and function.

Richard D, Clavel S, Huang Q, Sanchis D, Ricquier D.

Biochem Soc Trans. 2001 Nov;29(Pt 6):812-7. Review.

PMID:
11709080
34.

Transcriptional activation of the human ucp1 gene in a rodent cell line. Synergism of retinoids, isoproterenol, and thiazolidinedione is mediated by a multipartite response element.

del Mar Gonzalez-Barroso M, Pecqueur C, Gelly C, Sanchis D, Alves-Guerra MC, Bouillaud F, Ricquier D, Cassard-Doulcier AM.

J Biol Chem. 2000 Oct 13;275(41):31722-32.

35.

The mitochondrial uncoupling protein-2: current status.

Fleury C, Sanchis D.

Int J Biochem Cell Biol. 1999 Nov;31(11):1261-78. Review.

PMID:
10605819
36.

Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2.

Rial E, González-Barroso M, Fleury C, Iturrizaga S, Sanchis D, Jiménez-Jiménez J, Ricquier D, Goubern M, Bouillaud F.

EMBO J. 1999 Nov 1;18(21):5827-33.

37.

Brain distribution of UCP2 mRNA: in situ hybridization histochemistry studies.

Richard D, Huang Q, Sanchis D, Ricquier D.

Int J Obes Relat Metab Disord. 1999 Jun;23 Suppl 6:S53-5. Review.

PMID:
10454125
38.

Plasma oestrone-fatty acid ester levels are correlated with body fat mass in humans.

Fernández-Real JM, Sanchis D, Ricart W, Casamitjana R, Balada F, Remesar X, Alemany M.

Clin Endocrinol (Oxf). 1999 Feb;50(2):253-60.

PMID:
10396370
39.

Contributions of studies on uncoupling proteins to research on metabolic diseases.

Ricquier D, Fleury C, Larose M, Sanchis D, Pecqueur C, Raimbault S, Gelly C, Vacher D, Cassard-Doulcier AM, Lévi-Meyrueis C, Champigny O, Miroux B, Bouillaud F.

J Intern Med. 1999 Jun;245(6):637-42. Review.

40.

Corticosterone binding to tissues of adrenalectomized lean and obese Zucker rats.

Grasa MM, Cabot C, Balada F, Virgili J, Sanchis D, Monserrat C, Fernández-López JA, Remesar X, Alemany M.

Horm Metab Res. 1998 Dec;30(12):699-704.

PMID:
9930625
41.
42.

BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast.

Sanchis D, Fleury C, Chomiki N, Goubern M, Huang Q, Neverova M, Grégoire F, Easlick J, Raimbault S, Lévi-Meyrueis C, Miroux B, Collins S, Seldin M, Richard D, Warden C, Bouillaud F, Ricquier D.

J Biol Chem. 1998 Dec 18;273(51):34611-5.

43.

Skeletal muscle UCP2 and UCP3 gene expression in a rat cancer cachexia model.

Sanchís D, Busquets S, Alvarez B, Ricquier D, López-Soriano FJ, Argilés JM.

FEBS Lett. 1998 Oct 9;436(3):415-8.

44.

Effect of oleoyl-estrone administration on corticosterone binding to tissues of lean and obese Zucker rats.

Grasa MM, Cabot C, Adán C, Sanchis D, Balada F, Estruch J, Fernández-López JA, Remesar X, Alemany M.

J Steroid Biochem Mol Biol. 1998 Aug;66(3):165-9.

PMID:
9719451
45.

Distribution of the uncoupling protein 2 mRNA in the mouse brain.

Richard D, Rivest R, Huang Q, Bouillaud F, Sanchis D, Champigny O, Ricquier D.

J Comp Neurol. 1998 Aug 10;397(4):549-60.

PMID:
9699915
46.

Rats receiving the slimming agent oleoyl-estrone in liposomes (Merlin-2) decrease food intake but maintain thermogenesis.

Sanchis D, Balada F, Picó C, Grasa MM, Virgili J, Farrerons C, Palou A, Fernández-López JA, Remesar X, Alemany M.

Arch Physiol Biochem. 1997 Dec;105(7):663-72.

PMID:
9693713
47.

Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice.

Surwit RS, Wang S, Petro AE, Sanchis D, Raimbault S, Ricquier D, Collins S.

Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):4061-5.

48.

Structural determinants of oleoyl-estrone slimming effects.

Sanchis D, Balada F, Farrerons C, Virgili J, del Mar Grasa M, Adán C, Esteve M, Cabot C, Ardévol A, Vilà R, Fernández-López JA, Remesar X, Alemany M.

Life Sci. 1998;62(15):1349-59.

PMID:
9566777
49.

Differential short-term distribution of estrone and oleoyl-estrone administered in liposomes to lean and obese Zucker rats.

Balada F, Sanchis D, Grasa MM, Virgili J, Estruch J, Fernández-López JA, Remesar X, Alemany M.

Obes Res. 1998 Jan;6(1):34-9.

50.

Short-term handling of the slimming agent oleoyl-estrone in liposomes (Merlin-2) by the rat.

Sanchis D, Balada F, Grasa MM, Virgili J, Monserrat C, Fernández-López JA, Remesar X, Alemany M.

Mol Cell Biochem. 1997 Dec;177(1-2):153-7.

PMID:
9450657

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