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Items: 16


Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl-xL inhibition.

Nguyen TTT, Ishida CT, Shang E, Shu C, Torrini C, Zhang Y, Bianchetti E, Sanchez-Quintero MJ, Kleiner G, Quinzii CM, Westhoff MA, Karpel-Massler G, Canoll P, Siegelin MD.

EMBO Mol Med. 2019 Oct;11(10):e10769. doi: 10.15252/emmm.201910769. Epub 2019 Aug 29.


Bioavailability and cytosolic kinases modulate response to deoxynucleoside therapy in TK2 deficiency.

Lopez-Gomez C, Hewan H, Sierra C, Akman HO, Sanchez-Quintero MJ, Juanola-Falgarona M, Tadesse S, Tanji K, Konofagou EE, Hirano M.

EBioMedicine. 2019 Aug;46:356-367. doi: 10.1016/j.ebiom.2019.07.037. Epub 2019 Aug 2.


Cardiomyopathy and altered integrin-actin signaling in Fhl1 mutant female mice.

Kubota A, Juanola-Falgarona M, Emmanuele V, Sanchez-Quintero MJ, Kariya S, Sera F, Homma S, Tanji K, Quinzii CM, Hirano M.

Hum Mol Genet. 2019 Jan 15;28(2):209-219. doi: 10.1093/hmg/ddy299.


Characterization of the human homozygous R182W POLG2 mutation in mitochondrial DNA depletion syndrome.

Hoff KE, DeBalsi KL, Sanchez-Quintero MJ, Longley MJ, Hirano M, Naini AB, Copeland WC.

PLoS One. 2018 Aug 29;13(8):e0203198. doi: 10.1371/journal.pone.0203198. eCollection 2018.


Metabolic Reprogramming by Dual AKT/ERK Inhibition through Imipridones Elicits Unique Vulnerabilities in Glioblastoma.

Ishida CT, Zhang Y, Bianchetti E, Shu C, Nguyen TTT, Kleiner G, Sanchez-Quintero MJ, Quinzii CM, Westhoff MA, Karpel-Massler G, Prabhu VV, Allen JE, Siegelin MD.

Clin Cancer Res. 2018 Nov 1;24(21):5392-5406. doi: 10.1158/1078-0432.CCR-18-1040. Epub 2018 Jul 23.


Association of Antibodies to VAR2CSA and Merozoite Antigens with Pregnancy Outcomes in Women Living in Yaoundé, Cameroon.

Lloyd YM, Fang R, Bobbili N, Vanda K, Ngati E, Sanchez-Quintero MJ, Salanti A, Chen JJ, Leke RGF, Taylor DW.

Infect Immun. 2018 Aug 22;86(9). pii: e00166-18. doi: 10.1128/IAI.00166-18. Print 2018 Sep.


Combined HDAC and Bromodomain Protein Inhibition Reprograms Tumor Cell Metabolism and Elicits Synthetic Lethality in Glioblastoma.

Zhang Y, Ishida CT, Ishida W, Lo SL, Zhao J, Shu C, Bianchetti E, Kleiner G, Sanchez-Quintero MJ, Quinzii CM, Westhoff MA, Karpel-Massler G, Canoll P, Siegelin MD.

Clin Cancer Res. 2018 Aug 15;24(16):3941-3954. doi: 10.1158/1078-0432.CCR-18-0260. Epub 2018 May 15.


Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma.

Zhang Y, Ishida CT, Shu C, Kleiner G, Sanchez-Quintero MJ, Bianchetti E, Quinzii CM, Westhoff MA, Karpel-Massler G, Siegelin MD.

Sci Rep. 2018 May 9;8(1):7373. doi: 10.1038/s41598-018-25802-0.


PI3Kγ/δ and NOTCH1 Cross-Regulate Pathways That Define the T-cell Acute Lymphoblastic Leukemia Disease Signature.

Efimenko E, Davé UP, Lebedeva IV, Shen Y, Sanchez-Quintero MJ, Diolaiti D, Kung A, Lannutti BJ, Chen J, Realubit R, Niatsetskaya Z, Ten V, Karan C, Chen X, Califano A, Diacovo TG.

Mol Cancer Ther. 2017 Oct;16(10):2069-2082. doi: 10.1158/1535-7163.MCT-17-0141. Epub 2017 Jul 17.


Deoxycytidine and Deoxythymidine Treatment for Thymidine Kinase 2 Deficiency.

Lopez-Gomez C, Levy RJ, Sanchez-Quintero MJ, Juanola-Falgarona M, Barca E, Garcia-Diaz B, Tadesse S, Garone C, Hirano M.

Ann Neurol. 2017 May;81(5):641-652. doi: 10.1002/ana.24922. Epub 2017 May 4.


Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein.

Tang M, Gao G, Rueda CB, Yu H, Thibodeaux DN, Awano T, Engelstad KM, Sanchez-Quintero MJ, Yang H, Li F, Li H, Su Q, Shetler KE, Jones L, Seo R, McConathy J, Hillman EM, Noebels JL, De Vivo DC, Monani UR.

Nat Commun. 2017 Jan 20;8:14152. doi: 10.1038/ncomms14152.


Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway.

Ziosi M, Di Meo I, Kleiner G, Gao XH, Barca E, Sanchez-Quintero MJ, Tadesse S, Jiang H, Qiao C, Rodenburg RJ, Scalais E, Schuelke M, Willard B, Hatzoglou M, Tiranti V, Quinzii CM.

EMBO Mol Med. 2017 Jan;9(1):96-111. doi: 10.15252/emmm.201606356.


Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes.

Yamada M, Emmanuele V, Sanchez-Quintero MJ, Sun B, Lallos G, Paull D, Zimmer M, Pagett S, Prosser RW, Sauer MV, Hirano M, Egli D.

Cell Stem Cell. 2016 Jun 2;18(6):749-54. doi: 10.1016/j.stem.2016.04.001. Epub 2016 May 19.


Synergistic effect between amoxicillin and TLR ligands on dendritic cells from amoxicillin-delayed allergic patients.

Sanchez-Quintero MJ, Torres MJ, Blazquez AB, Gómez E, Fernandez TD, Doña I, Ariza A, Andreu I, Melendez L, Blanca M, Mayorga C.

PLoS One. 2013 Sep 16;8(9):e74198. doi: 10.1371/journal.pone.0074198. eCollection 2013.


Contact dermatitis caused by bromide compounds.

Salas M, Doña I, Fernandez T, Sanchez-Quintero MJ, Mayorga C, Blanca M, Torres Jaén MJ.

Contact Dermatitis. 2013 Sep;69(3):189-91. doi: 10.1111/cod.12087. No abstract available.


Immunological mechanisms underlying delayed-type hypersensitivity reactions to glatiramer acetate.

Mayorga C, Blazquez AB, Doña I, Gomez F, Chaves P, Sanchez-Quintero MJ, Blanca-López N, Melendez L, Blanca M, Torres MJ.

Ann Allergy Asthma Immunol. 2012 Jul;109(1):47-51. doi: 10.1016/j.anai.2012.05.002. Epub 2012 May 23.


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