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Items: 42


MicroRNA-31 Targets Thymic Stromal Lymphopoietin in Mucosal Infiltrated CD4+ T Cells: A Role in Achieving Mucosal Healing in Ulcerative Colitis?

Whiteoak SR, Claridge A, Balendran CA, Harris RJ, Gwiggner M, Bondanese VP, Erlandsson F, Hansen MB, Fraser Cummings JR, Sanchez-Elsner T.

Inflamm Bowel Dis. 2018 Jun 8. doi: 10.1093/ibd/izy213. [Epub ahead of print]


Genome-Wide Posttranscriptional Dysregulation by MicroRNAs in Human Asthma as Revealed by Frac-seq.

Martinez-Nunez RT, Rupani H, Platé M, Niranjan M, Chambers RC, Howarth PH, Sanchez-Elsner T.

J Immunol. 2018 Jul 1;201(1):251-263. doi: 10.4049/jimmunol.1701798. Epub 2018 May 16.


MicroRNA-31 and MicroRNA-155 Are Overexpressed in Ulcerative Colitis and Regulate IL-13 Signaling by Targeting Interleukin 13 Receptor α-1.

Gwiggner M, Martinez-Nunez RT, Whiteoak SR, Bondanese VP, Claridge A, Collins JE, Cummings JRF, Sanchez-Elsner T.

Genes (Basel). 2018 Feb 13;9(2). pii: E85. doi: 10.3390/genes9020085.


Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer.

Ganesan AP, Clarke J, Wood O, Garrido-Martin EM, Chee SJ, Mellows T, Samaniego-Castruita D, Singh D, Seumois G, Alzetani A, Woo E, Friedmann PS, King EV, Thomas GJ, Sanchez-Elsner T, Vijayanand P, Ottensmeier CH.

Nat Immunol. 2017 Aug;18(8):940-950. doi: 10.1038/ni.3775. Epub 2017 Jun 19.


Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology.

Brace PT, Tezera LB, Bielecka MK, Mellows T, Garay D, Tian S, Rand L, Green J, Jogai S, Steele AJ, Millar TM, Sanchez-Elsner T, Friedland JS, Proud CG, Elkington PT.

PLoS Pathog. 2017 Jun 1;13(6):e1006367. doi: 10.1371/journal.ppat.1006367. eCollection 2017 Jun.


IFN-γ Influences Epithelial Antiviral Responses via Histone Methylation of the RIG-I Promoter.

Spalluto CM, Singhania A, Cellura D, Woelk CH, Sanchez-Elsner T, Staples KJ, Wilkinson TMA.

Am J Respir Cell Mol Biol. 2017 Oct;57(4):428-438. doi: 10.1165/rcmb.2016-0392OC.


Modulation of nonsense mediated decay by rapamycin.

Martinez-Nunez RT, Wallace A, Coyne D, Jansson L, Rush M, Ennajdaoui H, Katzman S, Bailey J, Deinhardt K, Sanchez-Elsner T, Sanford JR.

Nucleic Acids Res. 2017 Apr 7;45(6):3448-3459. doi: 10.1093/nar/gkw1109.


Gene expression analysis of TIL rich HPV-driven head and neck tumors reveals a distinct B-cell signature when compared to HPV independent tumors.

Wood O, Woo J, Seumois G, Savelyeva N, McCann KJ, Singh D, Jones T, Peel L, Breen MS, Ward M, Garrido Martin E, Sanchez-Elsner T, Thomas G, Vijayanand P, Woelk CH, King E, Ottensmeier C; SPARC Consortium.

Oncotarget. 2016 Aug 30;7(35):56781-56797. doi: 10.18632/oncotarget.10788.


Toll-like Receptor 7 Is Reduced in Severe Asthma and Linked to an Altered MicroRNA Profile.

Rupani H, Martinez-Nunez RT, Dennison P, Lau LC, Jayasekera N, Havelock T, Francisco-Garcia AS, Grainge C, Howarth PH, Sanchez-Elsner T.

Am J Respir Crit Care Med. 2016 Jul 1;194(1):26-37. doi: 10.1164/rccm.201502-0280OC.


MicroRNAs in inflammatory bowel diseases: paradoxes and possibilities.

Whiteoak SR, Felwick R, Sanchez-Elsner T, Fraser Cummings JR.

Inflamm Bowel Dis. 2015 May;21(5):1160-5. doi: 10.1097/MIB.0000000000000288. Review.


Genetic factors in susceptibility to contact sensitivity.

Friedmann PS, Sanchez-Elsner T, Schnuch A.

Contact Dermatitis. 2015 May;72(5):263-74. doi: 10.1111/cod.12362. Epub 2015 Feb 25. Review.


Identification of host miRNAs that may limit human rhinovirus replication.

Bondanese VP, Francisco-Garcia A, Bedke N, Davies DE, Sanchez-Elsner T.

World J Biol Chem. 2014 Nov 26;5(4):437-56. doi: 10.4331/wjbc.v5.i4.437.


A microRNA network dysregulated in asthma controls IL-6 production in bronchial epithelial cells.

Martinez-Nunez RT, Bondanese VP, Louafi F, Francisco-Garcia AS, Rupani H, Bedke N, Holgate S, Howarth PH, Davies DE, Sanchez-Elsner T.

PLoS One. 2014 Oct 31;9(10):e111659. doi: 10.1371/journal.pone.0111659. eCollection 2014.


HIF-2α regulates NANOG expression in human embryonic stem cells following hypoxia and reoxygenation through the interaction with an Oct-Sox cis regulatory element.

Petruzzelli R, Christensen DR, Parry KL, Sanchez-Elsner T, Houghton FD.

PLoS One. 2014 Oct 1;9(10):e108309. doi: 10.1371/journal.pone.0108309. eCollection 2014.


MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD3.

Cheung KS, Sposito N, Stumpf PS, Wilson DI, Sanchez-Elsner T, Oreffo RO.

PLoS One. 2014 Jun 3;9(6):e98063. doi: 10.1371/journal.pone.0098063. eCollection 2014.


Estradiol downregulates NF-κb translocation by Ikbkg transcriptional repression in dendritic cells.

Lasarte S, Elsner D, Sanchez-Elsner T, Fernandez-Pineda A, López-Fernández LA, Corbí AL, Muñoz-Fernandez MA, Relloso M.

Genes Immun. 2013 Oct;14(7):462-9. doi: 10.1038/gene.2013.35. Epub 2013 Jul 25.


Manipulation of in vitro angiogenesis using peptide-coated gold nanoparticles.

Bartczak D, Muskens OL, Sanchez-Elsner T, Kanaras AG, Millar TM.

ACS Nano. 2013 Jun 25;7(6):5628-36. doi: 10.1021/nn402111z. Epub 2013 May 28.


Environmental oxygen tension regulates the energy metabolism and self-renewal of human embryonic stem cells.

Forristal CE, Christensen DR, Chinnery FE, Petruzzelli R, Parry KL, Sanchez-Elsner T, Houghton FD.

PLoS One. 2013 May 6;8(5):e62507. doi: 10.1371/journal.pone.0062507. Print 2013.


MicroRNAs and respiratory diseases.

Rupani H, Sanchez-Elsner T, Howarth P.

Eur Respir J. 2013 Mar;41(3):695-705. doi: 10.1183/09031936.00212011. Epub 2012 Jul 12. Review.


Interactions of human endothelial cells with gold nanoparticles of different morphologies.

Bartczak D, Muskens OL, Nitti S, Sanchez-Elsner T, Millar TM, Kanaras AG.

Small. 2012 Jan 9;8(1):122-30. doi: 10.1002/smll.201101422. Epub 2011 Nov 18.


Laser-induced damage and recovery of plasmonically targeted human endothelial cells.

Bartczak D, Muskens OL, Millar TM, Sanchez-Elsner T, Kanaras AG.

Nano Lett. 2011 Mar 9;11(3):1358-63. doi: 10.1021/nl104528s. Epub 2011 Feb 15.


Receptor-mediated interactions between colloidal gold nanoparticles and human umbilical vein endothelial cells.

Bartczak D, Sanchez-Elsner T, Louafi F, Millar TM, Kanaras AG.

Small. 2011 Feb 7;7(3):388-94. doi: 10.1002/smll.201001816. Epub 2010 Dec 27.


The interleukin 13 (IL-13) pathway in human macrophages is modulated by microRNA-155 via direct targeting of interleukin 13 receptor alpha1 (IL13Ralpha1).

Martinez-Nunez RT, Louafi F, Sanchez-Elsner T.

J Biol Chem. 2011 Jan 21;286(3):1786-94. doi: 10.1074/jbc.M110.169367. Epub 2010 Nov 19.


MicroRNA-155 targets SMAD2 and modulates the response of macrophages to transforming growth factor-{beta}.

Louafi F, Martinez-Nunez RT, Sanchez-Elsner T.

J Biol Chem. 2010 Dec 31;285(53):41328-36. doi: 10.1074/jbc.M110.146852. Epub 2010 Oct 29.


HeLa cell transfection using a novel sonoporation system.

Rodamporn S, Harris NR, Beeby SP, Boltryk RJ, Sanchez-Elsner T.

IEEE Trans Biomed Eng. 2011 Apr;58(4):927-34. doi: 10.1109/TBME.2010.2089521. Epub 2010 Oct 25.


Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1.

Purvis TL, Hearn T, Spalluto C, Knorz VJ, Hanley KP, Sanchez-Elsner T, Hanley NA, Wilson DI.

Gene. 2010 Jul 15;460(1-2):20-9. doi: 10.1016/j.gene.2010.03.015. Epub 2010 Apr 8.


Regulating the genome surveillance system: miRNAs and the p53 super family.

Bailey SG, Sanchez-Elsner T, Stephanou A, Cragg MS, Townsend PA.

Apoptosis. 2010 May;15(5):541-52. doi: 10.1007/s10495-010-0456-1. Review.


MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN).

Martinez-Nunez RT, Louafi F, Friedmann PS, Sanchez-Elsner T.

J Biol Chem. 2009 Jun 12;284(24):16334-42. doi: 10.1074/jbc.M109.011601. Epub 2009 Apr 22.


Noncoding RNAs of trithorax response elements recruit Drosophila Ash1 to Ultrabithorax.

Sanchez-Elsner T, Gou D, Kremmer E, Sauer F.

Science. 2006 Feb 24;311(5764):1118-23. Retraction in: McNutt M. Science. 2014 May 30;344(6187):981.


Lumican is down-regulated in cells expressing endoglin. Evidence for an inverse correlationship between Endoglin and Lumican expression.

Botella LM, Sanz-Rodriguez F, Sanchez-Elsner T, Langa C, Ramirez JR, Vary C, Roughley PJ, Bernabeu C.

Matrix Biol. 2004 Jan;22(7):561-72.


The heat is on with TAC1.

Sanchez-Elsner T, Sauer F.

Nat Cell Biol. 2004 Feb;6(2):92-3. No abstract available.


A cross-talk between hypoxia and TGF-beta orchestrates erythropoietin gene regulation through SP1 and Smads.

Sánchez-Elsner T, Ramírez JR, Sanz-Rodriguez F, Varela E, Bernabéu C, Botella LM.

J Mol Biol. 2004 Feb 6;336(1):9-24. Erratum in: J Mol Biol. 2004 Mar 19;337(2):499. Rodriguez-Sanz, Francisco [corrected to Sanz-Rodriguez, Francisco].


RUNX/AML and C/EBP factors regulate CD11a integrin expression in myeloid cells through overlapping regulatory elements.

Puig-Kröger A, Sanchez-Elsner T, Ruiz N, Andreu EJ, Prosper F, Jensen UB, Gil J, Erickson P, Drabkin H, Groner Y, Corbi AL.

Blood. 2003 Nov 1;102(9):3252-61. Epub 2003 Jul 10.


Transcriptional activation of endoglin and transforming growth factor-beta signaling components by cooperative interaction between Sp1 and KLF6: their potential role in the response to vascular injury.

Botella LM, Sánchez-Elsner T, Sanz-Rodriguez F, Kojima S, Shimada J, Guerrero-Esteo M, Cooreman MP, Ratziu V, Langa C, Vary CP, Ramirez JR, Friedman S, Bernabéu C.

Blood. 2002 Dec 1;100(12):4001-10.


Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways.

Sánchez-Elsner T, Botella LM, Velasco B, Langa C, Bernabéu C.

J Biol Chem. 2002 Nov 15;277(46):43799-808. Epub 2002 Sep 11.


Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II.

Guerrero-Esteo M, Sanchez-Elsner T, Letamendia A, Bernabeu C.

J Biol Chem. 2002 Aug 9;277(32):29197-209. Epub 2002 May 15.


Heat shock regulatory elements are present in telomeric repeats of Chironomus thummi.

Martinez JL, Sanchez-Elsner T, Morcillo G, Diez JL.

Nucleic Acids Res. 2001 Nov 15;29(22):4760-6.


Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression.

Sánchez-Elsner T, Botella LM, Velasco B, Corbí A, Attisano L, Bernabéu C.

J Biol Chem. 2001 Oct 19;276(42):38527-35. Epub 2001 Aug 2.


Identification of a critical Sp1 site within the endoglin promoter and its involvement in the transforming growth factor-beta stimulation.

Botella LM, Sánchez-Elsner T, Rius C, Corbí A, Bernabéu C.

J Biol Chem. 2001 Sep 14;276(37):34486-94. Epub 2001 Jun 29.


Polyomavirus enhancer-binding protein 2/core binding factor/acute myeloid leukemia factors contribute to the cell type-specific activity of the CD11a integrin gene promoter.

Puig-Kröger A, López-Rodriguez C, Relloso M, Sánchez-Elsner T, Nueda A, Muñoz E, Bernabéu C, Corbi AL.

J Biol Chem. 2000 Sep 15;275(37):28507-12.


Identification of a functional NF-kappa B site in the platelet endothelial cell adhesion molecule-1 promoter.

Botella LM, Puig-Kröger A, Almendro N, Sánchez-Elsner T, Muñoz E, Corbí A, Bernabéu C.

J Immunol. 2000 Feb 1;164(3):1372-8.

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