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Hemoglobin S and C affect biomechanical membrane properties of P. falciparum-infected erythrocytes.

Fröhlich B, Jäger J, Lansche C, Sanchez CP, Cyrklaff M, Buchholz B, Soubeiga ST, Simpore J, Ito H, Schwarz US, Lanzer M, Tanaka M.

Commun Biol. 2019 Aug 13;2:311. doi: 10.1038/s42003-019-0556-6. eCollection 2019.


Phosphomimetic substitution at Ser-33 of the chloroquine resistance transporter PfCRT reconstitutes drug responses in Plasmodium falciparum.

Sanchez CP, Moliner Cubel S, Nyboer B, Jankowska-Döllken M, Schaeffer-Reiss C, Ayoub D, Planelles G, Lanzer M.

J Biol Chem. 2019 Aug 23;294(34):12766-12778. doi: 10.1074/jbc.RA119.009464. Epub 2019 Jul 8.


Single-molecule imaging and quantification of the immune-variant adhesin VAR2CSA on knobs of Plasmodium falciparum-infected erythrocytes.

Sanchez CP, Karathanasis C, Sanchez R, Cyrklaff M, Jäger J, Buchholz B, Schwarz US, Heilemann M, Lanzer M.

Commun Biol. 2019 May 8;2:172. doi: 10.1038/s42003-019-0429-z. eCollection 2019.


The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes.

Lansche C, Dasanna AK, Quadt K, Fröhlich B, Missirlis D, Tétard M, Gamain B, Buchholz B, Sanchez CP, Tanaka M, Schwarz US, Lanzer M.

Commun Biol. 2018 Nov 30;1:211. doi: 10.1038/s42003-018-0223-3. eCollection 2018.


Experience with eribulin in the treatment of elderly women with metastatic breast cancer: case studies.

Garrido ML, Morago AJ, Rovira PS, Olarte PE, Sánchez CP, Sánchez LM.

Future Oncol. 2018 Mar;14(7s):21-27. doi: 10.2217/fon-2017-0357.


Profiling of the anti-malarial drug candidate SC83288 against artemisinins in Plasmodium falciparum.

Duffey M, Sanchez CP, Lanzer M.

Malar J. 2018 Mar 20;17(1):121. doi: 10.1186/s12936-018-2279-4.


Cortical and trabecular bone are equally affected in rats with renal failure and secondary hyperparathyroidism.

Bajwa NM, Sanchez CP, Lindsey RC, Watt H, Mohan S.

BMC Nephrol. 2018 Feb 2;19(1):24. doi: 10.1186/s12882-018-0822-8.


Iron is a substrate of the Plasmodium falciparum chloroquine resistance transporter PfCRT in Xenopus oocytes.

Bakouh N, Bellanca S, Nyboer B, Moliner Cubel S, Karim Z, Sanchez CP, Stein WD, Planelles G, Lanzer M.

J Biol Chem. 2017 Sep 29;292(39):16109-16121. doi: 10.1074/jbc.M117.805200. Epub 2017 Aug 2.


Knockout of the peroxiredoxin 5 homologue PFAOP does not affect the artemisinin susceptibility of Plasmodium falciparum.

Djuika CF, Staudacher V, Sanchez CP, Lanzer M, Deponte M.

Sci Rep. 2017 Jun 30;7(1):4410. doi: 10.1038/s41598-017-04277-5.


Genetic Knockout and Rescue Studies in Mice Unravel Abnormal Phosphorus Threshold in Hypophosphatemic Rickets.

Sanchez CP, Mohan S.

Endocrinology. 2017 Mar 1;158(3):455-457. doi: 10.1210/en.2017-00030. No abstract available.


Erratum: SC83288 is a clinical development candidate for the treatment of severe malaria.

Pegoraro S, Duffey M, Otto TD, Wang Y, Rösemann R, Baumgartner R, Fehler SK, Lucantoni L, Avery VM, Moreno-Sabater A, Mazier D, Vial HJ, Strobl S, Sanchez CP, Lanzer M.

Nat Commun. 2017 Apr 6;8:15273. doi: 10.1038/ncomms15273. No abstract available.


A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs.

Jida M, Sanchez CP, Urgin K, Ehrhardt K, Mounien S, Geyer A, Elhabiri M, Lanzer M, Davioud-Charvet E.

ACS Infect Dis. 2017 Feb 10;3(2):119-131. doi: 10.1021/acsinfecdis.5b00141. Epub 2016 Dec 7.


SC83288 is a clinical development candidate for the treatment of severe malaria.

Pegoraro S, Duffey M, Otto TD, Wang Y, Rösemann R, Baumgartner R, Fehler SK, Lucantoni L, Avery VM, Moreno-Sabater A, Mazier D, Vial HJ, Strobl S, Sanchez CP, Lanzer M.

Nat Commun. 2017 Jan 31;8:14193. doi: 10.1038/ncomms14193.


Immediate perception of a reward is distinct from the reward's long-term salience.

McGinnis JP, Jiang H, Agha MA, Sanchez CP, Lange J, Yu Z, Marion-Poll F, Si K.

Elife. 2016 Dec 22;5. pii: e22283. doi: 10.7554/eLife.22283.


Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes.

Cyrklaff M, Srismith S, Nyboer B, Burda K, Hoffmann A, Lasitschka F, Adjalley S, Bisseye C, Simpore J, Mueller AK, Sanchez CP, Frischknecht F, Lanzer M.

Nat Commun. 2016 Nov 8;7:13401. doi: 10.1038/ncomms13401.


A Putative Biochemical Engram of Long-Term Memory.

Li L, Sanchez CP, Slaughter BD, Zhao Y, Khan MR, Unruh JR, Rubinstein B, Si K.

Curr Biol. 2016 Dec 5;26(23):3143-3156. doi: 10.1016/j.cub.2016.09.054. Epub 2016 Nov 3.


Differential time-dependent volumetric and surface area changes and delayed induction of new permeation pathways in P. falciparum-infected hemoglobinopathic erythrocytes.

Waldecker M, Dasanna AK, Lansche C, Linke M, Srismith S, Cyrklaff M, Sanchez CP, Schwarz US, Lanzer M.

Cell Microbiol. 2017 Feb;19(2). doi: 10.1111/cmi.12650. Epub 2016 Aug 25.


Inpatient citrate-based hemodialysis in pediatric patients.

Fajardo C, Sanchez CP, Cutler D, Sahney S, Sheth R.

Pediatr Nephrol. 2016 Oct;31(10):1667-72. doi: 10.1007/s00467-016-3403-8. Epub 2016 May 11.


The double-edged sword of neutrophilic inflammation in bronchiectasis.

Martínez-García MÁ, Sánchez CP, Moreno RM.

Eur Respir J. 2015 Oct;46(4):898-900. doi: 10.1183/13993003.00961-2015. No abstract available.


Hemoglobin S and C affect protein export in Plasmodium falciparum-infected erythrocytes.

Kilian N, Srismith S, Dittmer M, Ouermi D, Bisseye C, Simpore J, Cyrklaff M, Sanchez CP, Lanzer M.

Biol Open. 2015 Feb 20;4(3):400-10. doi: 10.1242/bio.201410942.


Prokaryotic ancestry and gene fusion of a dual localized peroxiredoxin in malaria parasites.

Djuika CF, Huerta-Cepas J, Przyborski JM, Deil S, Sanchez CP, Doerks T, Bork P, Lanzer M, Deponte M.

Microb Cell. 2015 Jan 5;2(1):5-13. doi: 10.15698/mic2015.01.182.


Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites.

Bellanca S, Summers RL, Meyrath M, Dave A, Nash MN, Dittmer M, Sanchez CP, Stein WD, Martin RE, Lanzer M.

J Biol Chem. 2014 Dec 26;289(52):36336-51. doi: 10.1074/jbc.M114.614206. Epub 2014 Nov 6.


Cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced.

Rieger H, Yoshikawa HY, Quadt K, Nielsen MA, Sanchez CP, Salanti A, Tanaka M, Lanzer M.

Blood. 2015 Jan 8;125(2):383-91. doi: 10.1182/blood-2014-03-561019. Epub 2014 Oct 28.


Export of virulence proteins by malaria-infected erythrocytes involves remodeling of host actin cytoskeleton.

Rug M, Cyrklaff M, Mikkonen A, Lemgruber L, Kuelzer S, Sanchez CP, Thompson J, Hanssen E, O'Neill M, Langer C, Lanzer M, Frischknecht F, Maier AG, Cowman AF.

Blood. 2014 Nov 27;124(23):3459-68. doi: 10.1182/blood-2014-06-583054. Epub 2014 Aug 19.


A HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparum.

Sanchez CP, Liu CH, Mayer S, Nurhasanah A, Cyrklaff M, Mu J, Ferdig MT, Stein WD, Lanzer M.

PLoS Genet. 2014 May 15;10(5):e1004382. doi: 10.1371/journal.pgen.1004382. eCollection 2014 May.


Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite's chloroquine resistance transporter.

Summers RL, Dave A, Dolstra TJ, Bellanca S, Marchetti RV, Nash MN, Richards SN, Goh V, Schenk RL, Stein WD, Kirk K, Sanchez CP, Lanzer M, Martin RE.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):E1759-67. doi: 10.1073/pnas.1322965111. Epub 2014 Apr 11.


Haemoglobin S and C affect the motion of Maurer's clefts in Plasmodium falciparum-infected erythrocytes.

Kilian N, Dittmer M, Cyrklaff M, Ouermi D, Bisseye C, Simpore J, Frischknecht F, Sanchez CP, Lanzer M.

Cell Microbiol. 2013 Jul;15(7):1111-26. doi: 10.1111/cmi.12102. Epub 2013 Jan 20.


Transient transfection of Plasmodium vivax blood-stage parasites.

Sanchez CP, Pfahler J, Del Portillo HA, Lanzer M.

Methods Mol Biol. 2013;923:151-9.


Host actin remodeling and protection from malaria by hemoglobinopathies.

Cyrklaff M, Sanchez CP, Frischknecht F, Lanzer M.

Trends Parasitol. 2012 Nov;28(11):479-85. doi: 10.1016/ Epub 2012 Sep 11. Review.


Hemoglobins S and C interfere with actin remodeling in Plasmodium falciparum-infected erythrocytes.

Cyrklaff M, Sanchez CP, Kilian N, Bisseye C, Simpore J, Frischknecht F, Lanzer M.

Science. 2011 Dec 2;334(6060):1283-6. doi: 10.1126/science.1213775. Epub 2011 Nov 10.


Genetic linkage analyses redefine the roles of PfCRT and PfMDR1 in drug accumulation and susceptibility in Plasmodium falciparum.

Sanchez CP, Mayer S, Nurhasanah A, Stein WD, Lanzer M.

Mol Microbiol. 2011 Nov;82(4):865-78. doi: 10.1111/j.1365-2958.2011.07855.x. Epub 2011 Oct 18.


Genetic predisposition favors the acquisition of stable artemisinin resistance in malaria parasites.

Beez D, Sanchez CP, Stein WD, Lanzer M.

Antimicrob Agents Chemother. 2011 Jan;55(1):50-5. doi: 10.1128/AAC.00916-10. Epub 2010 Nov 1.


Experimental evolution of resistance to artemisinin combination therapy results in amplification of the mdr1 gene in a rodent malaria parasite.

Rodrigues LA, Henriques G, Borges ST, Hunt P, Sanchez CP, Martinelli A, Cravo P.

PLoS One. 2010 Jul 15;5(7):e11593. doi: 10.1371/journal.pone.0011593.


Transporters as mediators of drug resistance in Plasmodium falciparum.

Sanchez CP, Dave A, Stein WD, Lanzer M.

Int J Parasitol. 2010 Aug 15;40(10):1109-18. doi: 10.1016/j.ijpara.2010.04.001. Epub 2010 Apr 24. Review.


Complementation of Saccharomyces cerevisiaepik1ts by a phosphatidylinositol 4-kinase from Plasmodium falciparum.

Krüger T, Sanchez CP, Lanzer M.

Mol Biochem Parasitol. 2010 Aug;172(2):149-51. doi: 10.1016/j.molbiopara.2010.03.020. Epub 2010 Apr 8.


Apparent bias for P. falciparum parasites carrying the wild-type pfcrt allele in the placenta.

Oster N, Rohrbach P, Sanchez CP, Andrews KT, Kammer J, Coulibaly B, Stieglbauer G, Becher H, Lanzer M.

Parasitol Res. 2010 Apr;106(5):1065-70. doi: 10.1007/s00436-010-1756-7. Epub 2010 Feb 11.


Trafficking of the phosphoprotein PfCRT to the digestive vacuolar membrane in Plasmodium falciparum.

Kuhn Y, Sanchez CP, Ayoub D, Saridaki T, van Dorsselaer A, Lanzer M.

Traffic. 2010 Feb;11(2):236-49. doi: 10.1111/j.1600-0854.2009.01018.x. Epub 2009 Dec 12.


A global view of the nonprotein-coding transcriptome in Plasmodium falciparum.

Raabe CA, Sanchez CP, Randau G, Robeck T, Skryabin BV, Chinni SV, Kube M, Reinhardt R, Ng GH, Manickam R, Kuryshev VY, Lanzer M, Brosius J, Tang TH, Rozhdestvensky TS.

Nucleic Acids Res. 2010 Jan;38(2):608-17. doi: 10.1093/nar/gkp895. Epub 2009 Oct 28.


Growth-plate cartilage in chronic renal failure.

Sanchez CP.

Pediatr Nephrol. 2010 Apr;25(4):643-9. doi: 10.1007/s00467-009-1307-6. Epub 2009 Oct 9. Review.


Virulence and drug resistance in malaria parasites.

Stein WD, Sanchez CP, Lanzer M.

Trends Parasitol. 2009 Oct;25(10):441-3. doi: 10.1016/ Epub 2009 Sep 4.


Bone growth during rapamycin therapy in young rats.

Sanchez CP, He YZ.

BMC Pediatr. 2009 Jan 13;9:3. doi: 10.1186/1471-2431-9-3.


Polymorphisms within PfMDR1 alter the substrate specificity for anti-malarial drugs in Plasmodium falciparum.

Sanchez CP, Rotmann A, Stein WD, Lanzer M.

Mol Microbiol. 2008 Nov;70(4):786-98. doi: 10.1111/j.1365-2958.2008.06413.x. Epub 2008 Aug 18.


A conditional export system provides new insights into protein export in Plasmodium falciparum-infected erythrocytes.

Saridaki T, Sanchez CP, Pfahler J, Lanzer M.

Cell Microbiol. 2008 Dec;10(12):2483-95. doi: 10.1111/j.1462-5822.2008.01223.x. Epub 2008 Aug 5.


Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum.

Friebolin W, Jannack B, Wenzel N, Furrer J, Oeser T, Sanchez CP, Lanzer M, Yardley V, Becker K, Davioud-Charvet E.

J Med Chem. 2008 Mar 13;51(5):1260-77. doi: 10.1021/jm7009292. Epub 2008 Feb 9.


Dissecting the components of quinine accumulation in Plasmodium falciparum.

Sanchez CP, Stein WD, Lanzer M.

Mol Microbiol. 2008 Mar;67(5):1081-93. doi: 10.1111/j.1365-2958.2008.06108.x. Epub 2008 Jan 10.


Mineral metabolism and bone abnormalities in children with chronic renal failure.

Sanchez CP.

Rev Endocr Metab Disord. 2008 Jun;9(2):131-7. doi: 10.1007/s11154-007-9071-z. Epub 2008 Jan 4. Review.


Is PfCRT a channel or a carrier? Two competing models explaining chloroquine resistance in Plasmodium falciparum.

Sanchez CP, Stein WD, Lanzer M.

Trends Parasitol. 2007 Jul;23(7):332-9. Epub 2007 May 10. Review.


Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum.

Sanchez CP, Rohrbach P, McLean JE, Fidock DA, Stein WD, Lanzer M.

Mol Microbiol. 2007 Apr;64(2):407-20.

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