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Items: 1 to 50 of 73

1.

Prospectively Isolated Tetraspanin+ Neoblasts Are Adult Pluripotent Stem Cells Underlying Planaria Regeneration.

Zeng A, Li H, Guo L, Gao X, McKinney S, Wang Y, Yu Z, Park J, Semerad C, Ross E, Cheng LC, Davies E, Lei K, Wang W, Perera A, Hall K, Peak A, Box A, Sánchez Alvarado A.

Cell. 2018 Jun 14;173(7):1593-1608.e20. doi: 10.1016/j.cell.2018.05.006.

PMID:
29906446
2.

An adaptable chromosome preparation methodology for use in invertebrate research organisms.

Guo L, Accorsi A, He S, Guerrero-Hernández C, Sivagnanam S, McKinney S, Gibson M, Sánchez Alvarado A.

BMC Biol. 2018 Feb 26;16(1):25. doi: 10.1186/s12915-018-0497-4.

3.

To solve old problems, study new research organisms.

Sánchez Alvarado A.

Dev Biol. 2018 Jan 15;433(2):111-114. doi: 10.1016/j.ydbio.2017.09.018. Epub 2017 Nov 24. No abstract available.

PMID:
29179945
4.

Cellular, ultrastructural and molecular analyses of epidermal cell development in the planarian Schmidtea mediterranea.

Cheng LC, Tu KC, Seidel CW, Robb SMC, Guo F, Sánchez Alvarado A.

Dev Biol. 2018 Jan 15;433(2):357-373. doi: 10.1016/j.ydbio.2017.08.030. Epub 2017 Oct 31.

PMID:
29100657
5.

The miR-124 family of microRNAs is crucial for regeneration of the brain and visual system in the planarian Schmidtea mediterranea.

Sasidharan V, Marepally S, Elliott SA, Baid S, Lakshmanan V, Nayyar N, Bansal D, Sánchez Alvarado A, Vemula PK, Palakodeti D.

Development. 2017 Sep 15;144(18):3211-3223. doi: 10.1242/dev.144758. Epub 2017 Aug 14.

6.

PHRED-1 is a divergent neurexin-1 homolog that organizes muscle fibers and patterns organs during regeneration.

Adler CE, Sánchez Alvarado A.

Dev Biol. 2017 Jul 1;427(1):165-175. doi: 10.1016/j.ydbio.2017.04.012. Epub 2017 Apr 29.

7.

Egf Signaling Directs Neoblast Repopulation by Regulating Asymmetric Cell Division in Planarians.

Lei K, Thi-Kim Vu H, Mohan RD, McKinney SA, Seidel CW, Alexander R, Gotting K, Workman JL, Sánchez Alvarado A.

Dev Cell. 2016 Aug 22;38(4):413-29. doi: 10.1016/j.devcel.2016.07.012. Epub 2016 Aug 11.

8.

Pathogenic shifts in endogenous microbiota impede tissue regeneration via distinct activation of TAK1/MKK/p38.

Arnold CP, Merryman MS, Harris-Arnold A, McKinney SA, Seidel CW, Loethen S, Proctor KN, Guo L, Sánchez Alvarado A.

Elife. 2016 Jul 21;5. pii: e16793. doi: 10.7554/eLife.16793.

9.

Comparative and Transcriptome Analyses Uncover Key Aspects of Coding- and Long Noncoding RNAs in Flatworm Mitochondrial Genomes.

Ross E, Blair D, Guerrero-Hernández C, Sánchez Alvarado A.

G3 (Bethesda). 2016 May 3;6(5):1191-200. doi: 10.1534/g3.116.028175.

10.

Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo.

Duncan EM, Chitsazan AD, Seidel CW, Sánchez Alvarado A.

Cell Rep. 2015 Dec 29;13(12):2741-55. doi: 10.1016/j.celrep.2015.11.059. Epub 2015 Dec 17. Erratum in: Cell Rep. 2016 Oct 11;17 (3):930.

11.

Egr-5 is a post-mitotic regulator of planarian epidermal differentiation.

Tu KC, Cheng LC, T K Vu H, Lange JJ, McKinney SA, Seidel CW, Sánchez Alvarado A.

Elife. 2015 Oct 12;4:e10501. doi: 10.7554/eLife.10501.

12.

Types or States? Cellular Dynamics and Regenerative Potential.

Adler CE, Sánchez Alvarado A.

Trends Cell Biol. 2015 Nov;25(11):687-96. doi: 10.1016/j.tcb.2015.07.008. Epub 2015 Oct 1. Review.

13.

SmedGD 2.0: The Schmidtea mediterranea genome database.

Robb SM, Gotting K, Ross E, Sánchez Alvarado A.

Genesis. 2015 Aug;53(8):535-46. doi: 10.1002/dvg.22872. Epub 2015 Jul 17.

14.

Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ.

Thi-Kim Vu H, Rink JC, McKinney SA, McClain M, Lakshmanaperumal N, Alexander R, Sánchez Alvarado A.

Elife. 2015 Jun 9;4. doi: 10.7554/eLife.07405.

15.

Synaptonemal complex extension from clustered telomeres mediates full-length chromosome pairing in Schmidtea mediterranea.

Xiang Y, Miller DE, Ross EJ, Sánchez Alvarado A, Hawley RS.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):E5159-68. doi: 10.1073/pnas.1420287111. Epub 2014 Nov 17.

16.

Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria.

Adler CE, Seidel CW, McKinney SA, Sánchez Alvarado A.

Elife. 2014 Apr 15;3:e02238. doi: 10.7554/eLife.02238.

17.

Rethinking differentiation: stem cells, regeneration, and plasticity.

Sánchez Alvarado A, Yamanaka S.

Cell. 2014 Mar 27;157(1):110-9. doi: 10.1016/j.cell.2014.02.041. Review.

18.

Histone modifications and regeneration in the planarian Schmidtea mediterranea.

Robb SM, Sánchez Alvarado A.

Curr Top Dev Biol. 2014;108:71-93. doi: 10.1016/B978-0-12-391498-9.00004-8. Review.

PMID:
24512706
19.

Molecular cloning and characterization of SL3: a stem cell-specific SL RNA from the planarian Schmidtea mediterranea.

Rossi A, Ross EJ, Jack A, Sánchez Alvarado A.

Gene. 2014 Jan 1;533(1):156-67. doi: 10.1016/j.gene.2013.09.101. Epub 2013 Oct 8.

20.

Learning about loss.

Sánchez Alvarado A.

Elife. 2013 Sep 10;2:e00533. doi: 10.7554/eLife.00533. Erratum in: Elife. 2013;2:e1597.

21.

On the trail of a tropical disease.

Sánchez Alvarado A.

Elife. 2013 Jul 30;2:e01115. doi: 10.7554/eLife.01115.

22.

The history and enduring contributions of planarians to the study of animal regeneration.

Elliott SA, Sánchez Alvarado A.

Wiley Interdiscip Rev Dev Biol. 2013 May-Jun;2(3):301-26. doi: 10.1002/wdev.82. Epub 2012 Jul 23. Review.

23.

Q&A: what is regeneration, and why look to planarians for answers?

Sánchez Alvarado A.

BMC Biol. 2012 Nov 8;10:88. doi: 10.1186/1741-7007-10-88. No abstract available.

24.

Planarian immobilization, partial irradiation, and tissue transplantation.

Guedelhoefer OC 4th, Sánchez Alvarado A.

J Vis Exp. 2012 Aug 6;(66). pii: 4015. doi: 10.3791/4015.

25.

Cellular hyperproliferation and cancer as evolutionary variables.

Sánchez Alvarado A.

Curr Biol. 2012 Sep 11;22(17):R772-8. doi: 10.1016/j.cub.2012.08.008. Review.

26.

Amputation induces stem cell mobilization to sites of injury during planarian regeneration.

Guedelhoefer OC 4th, Sánchez Alvarado A.

Development. 2012 Oct;139(19):3510-20. doi: 10.1242/dev.082099. Epub 2012 Aug 16.

27.

TORC1 is required to balance cell proliferation and cell death in planarians.

Tu KC, Pearson BJ, Sánchez Alvarado A.

Dev Biol. 2012 May 15;365(2):458-69. doi: 10.1016/j.ydbio.2012.03.010. Epub 2012 Mar 16.

28.

Mitochondrial pathway of apoptosis is ancestral in metazoans.

Bender CE, Fitzgerald P, Tait SW, Llambi F, McStay GP, Tupper DO, Pellettieri J, Sánchez Alvarado A, Salvesen GS, Green DR.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4904-9. doi: 10.1073/pnas.1120680109. Epub 2012 Mar 13.

29.

Centrosome loss in the evolution of planarians.

Azimzadeh J, Wong ML, Downhour DM, Sánchez Alvarado A, Marshall WF.

Science. 2012 Jan 27;335(6067):461-3. doi: 10.1126/science.1214457. Epub 2012 Jan 5.

30.

Alejandro Sánchez Alvarado: bootstrapping flatworms into the molecular age.

Sánchez Alvarado A.

J Cell Biol. 2011 Aug 22;194(4):510-1. doi: 10.1083/jcb.1944pi. No abstract available.

31.

The maintenance and regeneration of the planarian excretory system are regulated by EGFR signaling.

Rink JC, Vu HT, Sánchez Alvarado A.

Development. 2011 Sep;138(17):3769-80. doi: 10.1242/dev.066852.

32.

De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics.

Adamidi C, Wang Y, Gruen D, Mastrobuoni G, You X, Tolle D, Dodt M, Mackowiak SD, Gogol-Doering A, Oenal P, Rybak A, Ross E, Sánchez Alvarado A, Kempa S, Dieterich C, Rajewsky N, Chen W.

Genome Res. 2011 Jul;21(7):1193-200. doi: 10.1101/gr.113779.110. Epub 2011 May 2.

33.

Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation response.

Gurley KA, Elliott SA, Simakov O, Schmidt HA, Holstein TW, Sánchez Alvarado A.

Dev Biol. 2010 Nov 1;347(1):24-39. doi: 10.1016/j.ydbio.2010.08.007. Epub 2010 Aug 10.

34.

Stem cells in animal models of regeneration.

Gurley KA, Sánchez Alvarado A.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.
2008 Dec 31.

35.

A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages.

Pearson BJ, Sánchez Alvarado A.

Development. 2010 Jan;137(2):213-21. doi: 10.1242/dev.044297.

36.

Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia.

Rink JC, Gurley KA, Elliott SA, Sánchez Alvarado A.

Science. 2009 Dec 4;326(5958):1406-10. doi: 10.1126/science.1178712. Epub 2009 Oct 22.

37.

Cell death and tissue remodeling in planarian regeneration.

Pellettieri J, Fitzgerald P, Watanabe S, Mancuso J, Green DR, Sánchez Alvarado A.

Dev Biol. 2010 Feb 1;338(1):76-85. doi: 10.1016/j.ydbio.2009.09.015. Epub 2009 Sep 18.

38.

Developmental biology: A cellular view of regeneration.

Sánchez Alvarado A.

Nature. 2009 Jul 2;460(7251):39-40. doi: 10.1038/460039a. No abstract available.

PMID:
19571870
39.

High-resolution profiling and discovery of planarian small RNAs.

Friedländer MR, Adamidi C, Han T, Lebedeva S, Isenbarger TA, Hirst M, Marra M, Nusbaum C, Lee WL, Jenkin JC, Sánchez Alvarado A, Kim JK, Rajewsky N.

Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11546-51. doi: 10.1073/pnas.0905222106. Epub 2009 Jun 29.

40.

Flow cytometry methods for the study of cell-cycle parameters of planarian stem cells.

Kang H, Sánchez Alvarado A.

Dev Dyn. 2009 May;238(5):1111-7. doi: 10.1002/dvdy.21928.

41.

Formaldehyde-based whole-mount in situ hybridization method for planarians.

Pearson BJ, Eisenhoffer GT, Gurley KA, Rink JC, Miller DE, Sánchez Alvarado A.

Dev Dyn. 2009 Feb;238(2):443-50. doi: 10.1002/dvdy.21849.

42.

Regeneration, stem cells, and the evolution of tumor suppression.

Pearson BJ, Sánchez Alvarado A.

Cold Spring Harb Symp Quant Biol. 2008;73:565-72. doi: 10.1101/sqb.2008.73.045. Epub 2009 Jan 15. Review.

PMID:
19150962
43.

Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling.

Oviedo NJ, Pearson BJ, Levin M, Sánchez Alvarado A.

Dis Model Mech. 2008 Sep-Oct;1(2-3):131-43; discussion 141. doi: 10.1242/dmm.000117. Epub 2008 Sep 18.

44.

Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterranea.

Eisenhoffer GT, Kang H, Sánchez Alvarado A.

Cell Stem Cell. 2008 Sep 11;3(3):327-39. doi: 10.1016/j.stem.2008.07.002.

45.

Gene nomenclature guidelines for the planarian Schmidtea mediterranea.

Reddien PW, Newmark PA, Sánchez Alvarado A.

Dev Dyn. 2008 Nov;237(11):3099-101. doi: 10.1002/dvdy.21623.

46.

Stem cells: time to check our premises.

Sánchez Alvarado A.

Cell Stem Cell. 2008 Jul 3;3(1):25-9. doi: 10.1016/j.stem.2008.06.013.

47.

Slicing across kingdoms: regeneration in plants and animals.

Birnbaum KD, Sánchez Alvarado A.

Cell. 2008 Feb 22;132(4):697-710. doi: 10.1016/j.cell.2008.01.040. Review.

48.

Cell turnover and adult tissue homeostasis: from humans to planarians.

Pellettieri J, Sánchez Alvarado A.

Annu Rev Genet. 2007;41:83-105. Review.

PMID:
18076325
49.

Beta-catenin defines head versus tail identity during planarian regeneration and homeostasis.

Gurley KA, Rink JC, Sánchez Alvarado A.

Science. 2008 Jan 18;319(5861):323-7. Epub 2007 Dec 6.

50.

MAKER: an easy-to-use annotation pipeline designed for emerging model organism genomes.

Cantarel BL, Korf I, Robb SM, Parra G, Ross E, Moore B, Holt C, Sánchez Alvarado A, Yandell M.

Genome Res. 2008 Jan;18(1):188-96. Epub 2007 Nov 19.

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