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Items: 1 to 50 of 390

1.

Drosophila, which lacks canonical transcription-coupled repair proteins, performs transcription-coupled repair.

Deger N, Yang Y, Lindsey-Boltz LA, Sancar A, Selby CP.

J Biol Chem. 2019 Nov 29;294(48):18092-18098. doi: 10.1074/jbc.AC119.011448. Epub 2019 Oct 17.

PMID:
31624146
2.

DCAF7 is required for maintaining the cellular levels of ERCC1-XPF and nucleotide excision repair.

Kawara H, Akahori R, Wakasugi M, Sancar A, Matsunaga T.

Biochem Biophys Res Commun. 2019 Oct 29;519(1):204-210. doi: 10.1016/j.bbrc.2019.08.147. Epub 2019 Sep 4.

PMID:
31493872
3.

Long-term, genome-wide kinetic analysis of the effect of the circadian clock and transcription on the repair of cisplatin-DNA adducts in the mouse liver.

Yang Y, Liu Z, Selby CP, Sancar A.

J Biol Chem. 2019 Aug 9;294(32):11960-11968. doi: 10.1074/jbc.RA119.009579. Epub 2019 Jun 19.

PMID:
31217280
4.

Mechanistic Study of TTF-1 Modulation of Cellular Sensitivity to Cisplatin.

Phelps CA, Lindsey-Boltz L, Sancar A, Mu D.

Sci Rep. 2019 May 29;9(1):7990. doi: 10.1038/s41598-019-44549-w.

5.

Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells.

Li W, Liu W, Kakoki A, Wang R, Adebali O, Jiang Y, Sancar A.

J Biol Chem. 2019 Apr 12;294(15):5914-5922. doi: 10.1074/jbc.RA119.007861. Epub 2019 Feb 26.

PMID:
30808711
6.

Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs.

Yimit A, Adebali O, Sancar A, Jiang Y.

Nat Commun. 2019 Jan 18;10(1):309. doi: 10.1038/s41467-019-08290-2.

7.

Genome-wide mapping of nucleotide excision repair with XR-seq.

Hu J, Li W, Adebali O, Yang Y, Oztas O, Selby CP, Sancar A.

Nat Protoc. 2019 Jan;14(1):248-282. doi: 10.1038/s41596-018-0093-7.

PMID:
30552409
8.

Single-nucleotide resolution analysis of nucleotide excision repair of ribosomal DNA in humans and mice.

Yang Y, Hu J, Selby CP, Li W, Yimit A, Jiang Y, Sancar A.

J Biol Chem. 2019 Jan 4;294(1):210-217. doi: 10.1074/jbc.RA118.006121. Epub 2018 Nov 9.

PMID:
30413533
9.

Comparative properties and functions of type 2 and type 4 pigeon cryptochromes.

Wang X, Jing C, Selby CP, Chiou YY, Yang Y, Wu W, Sancar A, Wang J.

Cell Mol Life Sci. 2018 Dec;75(24):4629-4641. doi: 10.1007/s00018-018-2920-y. Epub 2018 Sep 27.

10.

Cisplatin-DNA adduct repair of transcribed genes is controlled by two circadian programs in mouse tissues.

Yang Y, Adebali O, Wu G, Selby CP, Chiou YY, Rashid N, Hu J, Hogenesch JB, Sancar A.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4777-E4785. doi: 10.1073/pnas.1804493115. Epub 2018 May 7.

11.

Genome-wide excision repair in Arabidopsis is coupled to transcription and reflects circadian gene expression patterns.

Oztas O, Selby CP, Sancar A, Adebali O.

Nat Commun. 2018 Apr 17;9(1):1503. doi: 10.1038/s41467-018-03922-5.

12.

Single-nucleotide resolution dynamic repair maps of UV damage in Saccharomyces cerevisiae genome.

Li W, Adebali O, Yang Y, Selby CP, Sancar A.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3408-E3415. doi: 10.1073/pnas.1801687115. Epub 2018 Mar 26.

13.

RNA polymerase II is released from the DNA template during transcription-coupled repair in mammalian cells.

Chiou YY, Hu J, Sancar A, Selby CP.

J Biol Chem. 2018 Feb 16;293(7):2476-2486. doi: 10.1074/jbc.RA117.000971. Epub 2017 Dec 27.

14.

Guidelines for Genome-Scale Analysis of Biological Rhythms.

Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, Crowell AM, DeBruyne JP, Dijk DJ, DiTacchio L, Doyle FJ, Duffield GE, Dunlap JC, Eckel-Mahan K, Esser KA, FitzGerald GA, Forger DB, Francey LJ, Fu YH, Gachon F, Gatfield D, de Goede P, Golden SS, Green C, Harer J, Harmer S, Haspel J, Hastings MH, Herzel H, Herzog ED, Hoffmann C, Hong C, Hughey JJ, Hurley JM, de la Iglesia HO, Johnson C, Kay SA, Koike N, Kornacker K, Kramer A, Lamia K, Leise T, Lewis SA, Li J, Li X, Liu AC, Loros JJ, Martino TA, Menet JS, Merrow M, Millar AJ, Mockler T, Naef F, Nagoshi E, Nitabach MN, Olmedo M, Nusinow DA, Ptáček LJ, Rand D, Reddy AB, Robles MS, Roenneberg T, Rosbash M, Ruben MD, Rund SSC, Sancar A, Sassone-Corsi P, Sehgal A, Sherrill-Mix S, Skene DJ, Storch KF, Takahashi JS, Ueda HR, Wang H, Weitz C, Westermark PO, Wijnen H, Xu Y, Wu G, Yoo SH, Young M, Zhang EE, Zielinski T, Hogenesch JB.

J Biol Rhythms. 2017 Oct;32(5):380-393. doi: 10.1177/0748730417728663. Epub 2017 Nov 3.

15.

Mfd translocase is necessary and sufficient for transcription-coupled repair in Escherichia coli.

Adebali O, Sancar A, Selby CP.

J Biol Chem. 2017 Nov 10;292(45):18386-18391. doi: 10.1074/jbc.C117.818807. Epub 2017 Oct 6.

16.

Molecular mechanisms and genomic maps of DNA excision repair in Escherichia coli and humans.

Hu J, Selby CP, Adar S, Adebali O, Sancar A.

J Biol Chem. 2017 Sep 22;292(38):15588-15597. doi: 10.1074/jbc.R117.807453. Epub 2017 Aug 10. Review.

17.

Dynamic maps of UV damage formation and repair for the human genome.

Hu J, Adebali O, Adar S, Sancar A.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6758-6763. doi: 10.1073/pnas.1706522114. Epub 2017 Jun 12.

18.

Human genome-wide repair map of DNA damage caused by the cigarette smoke carcinogen benzo[a]pyrene.

Li W, Hu J, Adebali O, Adar S, Yang Y, Chiou YY, Sancar A.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6752-6757. doi: 10.1073/pnas.1706021114. Epub 2017 Jun 12.

19.

Claud S. Rupert (1919-2017): The Father of DNA Repair.

Sancar A.

Photochem Photobiol. 2017 Jul;93(4):1133-1134. doi: 10.1111/php.12792. Epub 2017 Jun 22. No abstract available.

PMID:
28513845
20.

Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.

Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM.

Cell Metab. 2017 May 2;25(5):1206. doi: 10.1016/j.cmet.2017.04.023. No abstract available.

21.

Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.

Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM.

Cell Metab. 2017 Apr 4;25(4):961-974.e4. doi: 10.1016/j.cmet.2017.03.019. Erratum in: Cell Metab. 2017 May 2;25(5):1206.

22.

Preface.

Sancar A.

Photochem Photobiol. 2017 Jan;93(1):4. doi: 10.1111/php.12700. No abstract available.

PMID:
28211125
23.

Biography.

Sancar A.

Photochem Photobiol. 2017 Jan;93(1):7-14. doi: 10.1111/php.12731. No abstract available.

PMID:
28211123
24.

Oliver Smithies (1925-2017).

Sancar A.

Science. 2017 Feb 17;355(6326):695. doi: 10.1126/science.aam8635. No abstract available.

PMID:
28209861
25.

Genome-wide transcription-coupled repair in Escherichia coli is mediated by the Mfd translocase.

Adebali O, Chiou YY, Hu J, Sancar A, Selby CP.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2116-E2125. doi: 10.1073/pnas.1700230114. Epub 2017 Feb 6.

26.

It Is Chemistry but Not Your Grandfather's Chemistry.

Sancar A, Zhong D.

Biochemistry. 2017 Jan 10;56(1):1-2. doi: 10.1021/acs.biochem.6b01262. No abstract available.

PMID:
28068777
27.

Bifurcating electron-transfer pathways in DNA photolyases determine the repair quantum yield.

Zhang M, Wang L, Shu S, Sancar A, Zhong D.

Science. 2016 Oct 14;354(6309):209-213.

PMID:
27738168
28.

Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution.

Hu J, Lieb JD, Sancar A, Adar S.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11507-11512. Epub 2016 Sep 29.

29.

Mammalian Period represses and de-represses transcription by displacing CLOCK-BMAL1 from promoters in a Cryptochrome-dependent manner.

Chiou YY, Yang Y, Rashid N, Ye R, Selby CP, Sancar A.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6072-E6079. Epub 2016 Sep 29.

30.

SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding.

Jang H, Lee GY, Selby CP, Lee G, Jeon YG, Lee JH, Cheng KK, Titchenell P, Birnbaum MJ, Xu A, Sancar A, Kim JB.

Nat Commun. 2016 Jul 14;7:12180. doi: 10.1038/ncomms12180.

31.

Mechanisms of DNA Repair by Photolyase and Excision Nuclease (Nobel Lecture).

Sancar A.

Angew Chem Int Ed Engl. 2016 Jul 18;55(30):8502-27. doi: 10.1002/anie.201601524. Epub 2016 Jun 23. Review.

PMID:
27337655
32.

The 2015 Nobel Prize in Chemistry The Discovery of Essential Mechanisms that Repair DNA Damage.

Lindahl T, Modrich P, Sancar A.

J Assoc Genet Technol. 2016;42(1):37-41.

PMID:
27183258
33.

Nucleotide excision repair by dual incisions in plants.

Canturk F, Karaman M, Selby CP, Kemp MG, Kulaksiz-Erkmen G, Hu J, Li W, Lindsey-Boltz LA, Sancar A.

Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4706-10. doi: 10.1073/pnas.1604097113. Epub 2016 Apr 11.

34.

Genome-wide kinetics of DNA excision repair in relation to chromatin state and mutagenesis.

Adar S, Hu J, Lieb JD, Sancar A.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):E2124-33. doi: 10.1073/pnas.1603388113. Epub 2016 Mar 28.

35.

ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress.

Kemp MG, Sancar A.

J Biol Chem. 2016 Apr 22;291(17):9330-42. doi: 10.1074/jbc.M116.719740. Epub 2016 Mar 3.

36.

Analysis of Ribonucleotide Removal from DNA by Human Nucleotide Excision Repair.

Lindsey-Boltz LA, Kemp MG, Hu J, Sancar A.

J Biol Chem. 2015 Dec 11;290(50):29801-7. doi: 10.1074/jbc.M115.695254. Epub 2015 Oct 21.

37.

An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells: NUCLEOTIDE EXCISION REPAIR, DNA DAMAGE CHECKPOINT, AND APOPTOSIS.

Choi JH, Kim SY, Kim SK, Kemp MG, Sancar A.

J Biol Chem. 2015 Nov 27;290(48):28812-21. doi: 10.1074/jbc.M115.690354. Epub 2015 Oct 5.

38.

Endoscopic Mucosal Resection of Jejunal Polyps using Double-Balloon Enteroscopy.

Kröner PT, Sancar A, Fry LC, Neumann H, Mönkemüller K.

GE Port J Gastroenterol. 2015 Jul 2;22(4):137-142. doi: 10.1016/j.jpge.2015.04.005. eCollection 2015 Jul-Aug.

39.

The molecular origin of high DNA-repair efficiency by photolyase.

Tan C, Liu Z, Li J, Guo X, Wang L, Sancar A, Zhong D.

Nat Commun. 2015 Jun 11;6:7302. doi: 10.1038/ncomms8302.

PMID:
26065359
40.

Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution.

Hu J, Adar S, Selby CP, Lieb JD, Sancar A.

Genes Dev. 2015 May 1;29(9):948-60. doi: 10.1101/gad.261271.115.

41.

UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1).

Kemp MG, Lindsey-Boltz LA, Sancar A.

J Biol Chem. 2015 May 8;290(19):12184-94. doi: 10.1074/jbc.M115.649301. Epub 2015 Mar 19.

42.

RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling.

Lindsey-Boltz LA, Kemp MG, Capp C, Sancar A.

Cell Cycle. 2015;14(1):99-108. doi: 10.4161/15384101.2014.967076.

43.

The circadian clock controls sunburn apoptosis and erythema in mouse skin.

Gaddameedhi S, Selby CP, Kemp MG, Ye R, Sancar A.

J Invest Dermatol. 2015 Apr;135(4):1119-1127. doi: 10.1038/jid.2014.508. Epub 2014 Nov 28.

44.

Circadian clock, cancer, and chemotherapy.

Sancar A, Lindsey-Boltz LA, Gaddameedhi S, Selby CP, Ye R, Chiou YY, Kemp MG, Hu J, Lee JH, Ozturk N.

Biochemistry. 2015 Jan 20;54(2):110-23. doi: 10.1021/bi5007354. Epub 2014 Oct 29.

45.

Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock.

Ye R, Selby CP, Chiou YY, Ozkan-Dagliyan I, Gaddameedhi S, Sancar A.

Genes Dev. 2014 Sep 15;28(18):1989-98. doi: 10.1101/gad.249417.114.

46.

DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair.

Kemp MG, Gaddameedhi S, Choi JH, Hu J, Sancar A.

J Biol Chem. 2014 Sep 19;289(38):26574-83. doi: 10.1074/jbc.M114.597088. Epub 2014 Aug 8.

47.

Direct determination of resonance energy transfer in photolyase: structural alignment for the functional state.

Tan C, Guo L, Ai Y, Li J, Wang L, Sancar A, Luo Y, Zhong D.

J Phys Chem A. 2014 Nov 13;118(45):10522-30. doi: 10.1021/jp504349b. Epub 2014 Jul 29.

48.

Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system.

Lindsey-Boltz LA, Kemp MG, Reardon JT, DeRocco V, Iyer RR, Modrich P, Sancar A.

J Biol Chem. 2014 Feb 21;289(8):5074-82. doi: 10.1074/jbc.M113.542787. Epub 2014 Jan 8.

49.

Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression.

Annayev Y, Adar S, Chiou YY, Lieb JD, Sancar A, Ye R.

J Biol Chem. 2014 Feb 21;289(8):5013-24. doi: 10.1074/jbc.M113.534651. Epub 2014 Jan 2.

50.

Mechanism of photosignaling by Drosophila cryptochrome: role of the redox status of the flavin chromophore.

Ozturk N, Selby CP, Zhong D, Sancar A.

J Biol Chem. 2014 Feb 21;289(8):4634-42. doi: 10.1074/jbc.M113.542498. Epub 2013 Dec 30.

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