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Items: 1 to 50 of 123

1.

Surgical morbidity of transsylvian versus transcortical approaches to insular gliomas.

Przybylowski CJ, Baranoski JF, So VM, Wilson J, Sanai N.

J Neurosurg. 2019 Apr 5:1-8. doi: 10.3171/2018.12.JNS183075. [Epub ahead of print]

PMID:
30952129
2.

Trends and Challenges for the Clinical Adoption of Fluorescence-Guided Surgery.

Liu JTC, Sanai N.

J Nucl Med. 2019 Jun;60(6):756-757. doi: 10.2967/jnumed.119.226795. Epub 2019 Mar 15. No abstract available.

PMID:
30877178
3.

Accurate Patient-Specific Machine Learning Models of Glioblastoma Invasion Using Transfer Learning.

Hu LS, Yoon H, Eschbacher JM, Baxter LC, Dueck AC, Nespodzany A, Smith KA, Nakaji P, Xu Y, Wang L, Karis JP, Hawkins-Daarud AJ, Singleton KW, Jackson PR, Anderies BJ, Bendok BR, Zimmerman RS, Quarles C, Porter-Umphrey AB, Mrugala MM, Sharma A, Hoxworth JM, Sattur MG, Sanai N, Koulemberis PE, Krishna C, Mitchell JR, Wu T, Tran NL, Swanson KR, Li J.

AJNR Am J Neuroradiol. 2019 Mar;40(3):418-425. doi: 10.3174/ajnr.A5981. Epub 2019 Feb 28.

PMID:
30819771
4.

Handheld line-scanned dual-axis confocal microscope with pistoned MEMS actuation for flat-field fluorescence imaging.

Wei L, Yin C, Fujita Y, Sanai N, Liu JTC.

Opt Lett. 2019 Feb 1;44(3):671-674. doi: 10.1364/OL.44.000671.

PMID:
30702707
5.

Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry.

Bao X, Wu J, Sanai N, Li J.

J Pharm Biomed Anal. 2019 Mar 20;166:197-204. doi: 10.1016/j.jpba.2019.01.017. Epub 2019 Jan 11.

PMID:
30660034
6.

Resection and permanent intracranial brachytherapy using modular, biocompatible cesium-131 implants: results in 20 recurrent, previously irradiated meningiomas.

Brachman DG, Youssef E, Dardis CJ, Sanai N, Zabramski JM, Smith KA, Little AS, Shetter AG, Thomas T, McBride HL, Sorensen S, Spetzler RF, Nakaji P.

J Neurosurg. 2018 Dec 21:1-10. doi: 10.3171/2018.7.JNS18656. [Epub ahead of print]

PMID:
30579269
7.

Visualization technologies for 5-ALA-based fluorescence-guided surgeries.

Wei L, Roberts DW, Sanai N, Liu JTC.

J Neurooncol. 2019 Feb;141(3):495-505. doi: 10.1007/s11060-018-03077-9. Epub 2018 Dec 15. Review.

PMID:
30554344
8.

How to Build a Neurosurgical Oncology Practice Specializing in Gliomas.

Sanai N.

Neurosurg Clin N Am. 2019 Jan;30(1):129-136. doi: 10.1016/j.nec.2018.08.013. Epub 2018 Nov 1. Review.

9.

Fluorescence-guided surgery with aminolevulinic acid for low-grade gliomas.

Hendricks BK, Sanai N, Stummer W.

J Neurooncol. 2019 Jan;141(1):13-18. doi: 10.1007/s11060-018-03026-6. Epub 2018 Oct 26. Review.

PMID:
30367383
10.

Laboratory Evaluation of a Robotic Operative Microscope - Visualization Platform for Neurosurgery.

Belykh EG, Zhao X, Cavallo C, Bohl MA, Yagmurlu K, Aklinski JL, Byvaltsev VA, Sanai N, Spetzler RF, Lawton MT, Nakaji P, Preul MC.

Cureus. 2018 Jul 30;10(7):e3072. doi: 10.7759/cureus.3072.

11.

Contralateral interhemispheric, transfalcine approach with asleep motor mapping for parasagittal lesions near the medial precentral gyrus.

Mooney MA, Sanai N.

Neurosurg Focus. 2018 Oct;45(VideoSuppl2):V6. doi: 10.3171/2018.10.FocusVid.18292.

PMID:
30269552
12.

Introduction: Advances in intraoperative brain mapping.

Byrne RW, Sanai N, Landeiro JA, Duffau H.

Neurosurg Focus. 2018 Oct;45(VideoSuppl2):Intro. doi: 10.3171/2018.10.FocusVid.Intro. No abstract available.

PMID:
30269549
13.

A three-dimensional (3D) organotypic microfluidic model for glioma stem cells - Vascular interactions.

Truong D, Fiorelli R, Barrientos ES, Melendez EL, Sanai N, Mehta S, Nikkhah M.

Biomaterials. 2019 Apr;198:63-77. doi: 10.1016/j.biomaterials.2018.07.048. Epub 2018 Jul 30.

PMID:
30098794
14.

Rethinking medulloblastoma from a targeted therapeutics perspective.

Hashimoto Y, Penas-Prado M, Zhou S, Wei J, Khatua S, Hodges TR, Sanai N, Xiu J, Gatalica Z, Kim L, Kesari S, Rao G, Spetzler D, Heimberger A.

J Neurooncol. 2018 Sep;139(3):713-720. doi: 10.1007/s11060-018-2917-2. Epub 2018 Jun 5.

15.

Multiplatform profiling of meningioma provides molecular insight and prioritization of drug targets for rational clinical trial design.

Everson RG, Hashimoto Y, Freeman JL, Hodges TR, Huse J, Zhou S, Xiu J, Spetzler D, Sanai N, Kim L, Kesari S, Brenner A, De Monte F, Heimberger A, Raza SM.

J Neurooncol. 2018 Sep;139(2):469-478. doi: 10.1007/s11060-018-2891-8. Epub 2018 May 30.

PMID:
29846894
16.

Phase 0 Trial of AZD1775 in First-Recurrence Glioblastoma Patients.

Sanai N, Li J, Boerner J, Stark K, Wu J, Kim S, Derogatis A, Mehta S, Dhruv HD, Heilbrun LK, Berens ME, LoRusso PM.

Clin Cancer Res. 2018 Aug 15;24(16):3820-3828. doi: 10.1158/1078-0432.CCR-17-3348. Epub 2018 May 24.

PMID:
29798906
17.

Preoperative Embolization of Skull Base Meningiomas: Outcomes in the Onyx Era.

Przybylowski CJ, Baranoski JF, See AP, Flores BC, Almefty RO, Ding D, Chapple KM, Sanai N, Ducruet AF, Albuquerque FC.

World Neurosurg. 2018 Aug;116:e371-e379. doi: 10.1016/j.wneu.2018.04.208. Epub 2018 May 9.

PMID:
29751190
18.

Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas.

Ferguson SD, Zhou S, Huse JT, de Groot JF, Xiu J, Subramaniam DS, Mehta S, Gatalica Z, Swensen J, Sanai N, Spetzler D, Heimberger AB.

J Neuropathol Exp Neurol. 2018 Jun 1;77(6):437-442. doi: 10.1093/jnen/nly022.

19.

A liquid chromatography with tandem mass spectrometry method for quantitating total and unbound ceritinib in patient plasma and brain tumor.

Bao X, Wu J, Sanai N, Li J.

J Pharm Anal. 2018 Feb;8(1):20-26. doi: 10.1016/j.jpha.2017.07.007. Epub 2017 Jul 14.

20.

Ependymomas overexpress chemoresistance and DNA repair-related proteins.

Ferguson SD, Zhou S, Xiu J, Hashimoto Y, Sanai N, Kim L, Kesari S, de Groot J, Spetzler D, Heimberger AB.

Oncotarget. 2017 Dec 15;9(8):7822-7831. doi: 10.18632/oncotarget.23288. eCollection 2018 Jan 30.

21.

Surgical oncology for gliomas: the state of the art.

Sanai N, Berger MS.

Nat Rev Clin Oncol. 2018 Feb;15(2):112-125. doi: 10.1038/nrclinonc.2017.171. Epub 2017 Nov 21. Review.

PMID:
29158591
22.

Quantitative and Mechanistic Understanding of AZD1775 Penetration across Human Blood-Brain Barrier in Glioblastoma Patients Using an IVIVE-PBPK Modeling Approach.

Li J, Wu J, Bao X, Honea N, Xie Y, Kim S, Sparreboom A, Sanai N.

Clin Cancer Res. 2017 Dec 15;23(24):7454-7466. doi: 10.1158/1078-0432.CCR-17-0983. Epub 2017 Sep 19.

23.

PNIPAAm-co-Jeffamine® (PNJ) scaffolds as in vitro models for niche enrichment of glioblastoma stem-like cells.

Heffernan JM, McNamara JB, Borwege S, Vernon BL, Sanai N, Mehta S, Sirianni RW.

Biomaterials. 2017 Oct;143:149-158. doi: 10.1016/j.biomaterials.2017.05.007. Epub 2017 May 6.

24.

Impact of removed tumor volume and location on patient outcome in glioblastoma.

Awad AW, Karsy M, Sanai N, Spetzler R, Zhang Y, Xu Y, Mahan MA.

J Neurooncol. 2017 Oct;135(1):161-171. doi: 10.1007/s11060-017-2562-1. Epub 2017 Jul 6.

PMID:
28685405
25.

Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-β Pathway.

Singh SK, Fiorelli R, Kupp R, Rajan S, Szeto E, Lo Cascio C, Maire CL, Sun Y, Alberta JA, Eschbacher JM, Ligon KL, Berens ME, Sanai N, Mehta S.

Cell Rep. 2017 Jun 13;19(11):2410-2412. doi: 10.1016/j.celrep.2017.05.039. No abstract available.

26.

Surgical Management of Incidental Gliomas.

Noorani I, Sanai N.

Neurosurg Clin N Am. 2017 Jul;28(3):397-406. doi: 10.1016/j.nec.2017.02.008. Review.

PMID:
28600014
27.

An extent of resection threshold for seizure freedom in patients with low-grade gliomas.

Xu DS, Awad AW, Mehalechko C, Wilson JR, Ashby LS, Coons SW, Sanai N.

J Neurosurg. 2018 Apr;128(4):1084-1090. doi: 10.3171/2016.12.JNS161682. Epub 2017 May 26.

PMID:
28548599
28.

Optical-sectioning microscopy of protoporphyrin IX fluorescence in human gliomas: standardization and quantitative comparison with histology.

Wei L, Chen Y, Yin C, Borwege S, Sanai N, Liu JTC.

J Biomed Opt. 2017 Apr 1;22(4):46005. doi: 10.1117/1.JBO.22.4.046005.

29.

Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories.

Mirzadeh Z, Kusne Y, Duran-Moreno M, Cabrales E, Gil-Perotin S, Ortiz C, Chen B, Garcia-Verdugo JM, Sanai N, Alvarez-Buylla A.

Nat Commun. 2017 Jan 9;8:13759. doi: 10.1038/ncomms13759.

30.

Future directions of operative neuro-oncology.

Rennert RC, Santiago-Dieppa DR, Figueroa J, Sanai N, Carter BS.

J Neurooncol. 2016 Nov;130(2):377-382. Epub 2016 Jun 22. Review.

PMID:
27334902
31.

Lineage-Restricted OLIG2-RTK Signaling Governs the Molecular Subtype of Glioma Stem-like Cells.

Kupp R, Shtayer L, Tien AC, Szeto E, Sanai N, Rowitch DH, Mehta S.

Cell Rep. 2016 Sep 13;16(11):2838-2845. doi: 10.1016/j.celrep.2016.08.040.

32.

Defining Glioblastoma Resectability Through the Wisdom of the Crowd: A Proof-of-Principle Study.

Sonabend AM, Zacharia BE, Cloney MB, Sonabend A, Showers C, Ebiana V, Nazarian M, Swanson KR, Baldock A, Brem H, Bruce JN, Butler W, Cahill DP, Carter B, Orringer DA, Roberts DW, Sagher O, Sanai N, Schwartz TH, Silbergeld DL, Sisti MB, Thompson RC, Waziri AE, Ghogawala Z, McKhann G 2nd.

Neurosurgery. 2017 Apr 1;80(4):590-601. doi: 10.1227/NEU.0000000000001374.

33.

Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-β Pathway.

Singh SK, Fiorelli R, Kupp R, Rajan S, Szeto E, Lo Cascio C, Maire CL, Sun Y, Alberta JA, Eschbacher JM, Ligon KL, Berens ME, Sanai N, Mehta S.

Cell Rep. 2016 Jul 26;16(4):950-966. doi: 10.1016/j.celrep.2016.06.045. Epub 2016 Jul 7. Erratum in: Cell Rep. 2017 Jun 13;19(11):2410-2412.

34.

Brain Invasion in Meningiomas: Incidence and Correlations with Clinical Variables and Prognosis.

Spille DC, Heß K, Sauerland C, Sanai N, Stummer W, Paulus W, Brokinkel B.

World Neurosurg. 2016 Sep;93:346-54. doi: 10.1016/j.wneu.2016.06.055. Epub 2016 Jun 22.

PMID:
27344043
35.

An aqueous normal-phase chromatography coupled with tandem mass spectrometry method for determining unbound brain-to-plasma concentration ratio of AZD1775, a Wee1 kinase inhibitor, in patients with glioblastoma.

Wu J, Sanai N, Bao X, LoRusso P, Li J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Aug 15;1028:25-32. doi: 10.1016/j.jchromb.2016.05.050. Epub 2016 Jun 3.

PMID:
27318641
36.

Miniature in vivo MEMS-based line-scanned dual-axis confocal microscope for point-of-care pathology.

Yin C, Glaser AK, Leigh SY, Chen Y, Wei L, Pillai PC, Rosenberg MC, Abeytunge S, Peterson G, Glazowski C, Sanai N, Mandella MJ, Rajadhyaksha M, Liu JT.

Biomed Opt Express. 2016 Jan 5;7(2):251-63. doi: 10.1364/BOE.7.000251. eCollection 2016 Feb 1.

37.

Surgical approaches for the gliomas.

Watts C, Sanai N.

Handb Clin Neurol. 2016;134:51-69. doi: 10.1016/B978-0-12-802997-8.00004-9. Review.

PMID:
26948348
38.

Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies.

Xiu J, Piccioni D, Juarez T, Pingle SC, Hu J, Rudnick J, Fink K, Spetzler DB, Maney T, Ghazalpour A, Bender R, Gatalica Z, Reddy S, Sanai N, Idbaih A, Glantz M, Kesari S.

Oncotarget. 2016 Apr 19;7(16):21556-69. doi: 10.18632/oncotarget.7722.

39.

Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation.

Liu Q, Sanai N, Jin WN, La Cava A, Van Kaer L, Shi FD.

Nat Neurosci. 2016 Feb;19(2):243-52. doi: 10.1038/nn.4211. Epub 2016 Jan 11.

40.

Video-rate in vivo fluorescence imaging with a line-scanned dual-axis confocal microscope.

Chen Y, Wang D, Khan A, Wang Y, Borwege S, Sanai N, Liu JT.

J Biomed Opt. 2015 Oct;20(10):106011. doi: 10.1117/1.JBO.20.10.106011.

41.

Detection of human brain tumor infiltration with quantitative stimulated Raman scattering microscopy.

Ji M, Lewis S, Camelo-Piragua S, Ramkissoon SH, Snuderl M, Venneti S, Fisher-Hubbard A, Garrard M, Fu D, Wang AC, Heth JA, Maher CO, Sanai N, Johnson TD, Freudiger CW, Sagher O, Xie XS, Orringer DA.

Sci Transl Med. 2015 Oct 14;7(309):309ra163. doi: 10.1126/scitranslmed.aab0195.

42.

Biopsy vs. extensive resection for first recurrence of glioblastoma: is a prospective clinical trial warranted?

Dardis C, Ashby L, Shapiro W, Sanai N.

BMC Res Notes. 2015 Sep 4;8:414. doi: 10.1186/s13104-015-1386-3.

43.

The SVZ and Its Relationship to Stem Cell Based Neuro-oncogenesis.

Kusne Y, Sanai N.

Adv Exp Med Biol. 2015;853:23-32. doi: 10.1007/978-3-319-16537-0_2. Review.

PMID:
25895705
44.

Comparing high-resolution microscopy techniques for potential intraoperative use in guiding low-grade glioma resections.

Meza D, Wang D, Wang Y, Borwege S, Sanai N, Liu JT.

Lasers Surg Med. 2015 Apr;47(4):289-95. doi: 10.1002/lsm.22347. Epub 2015 Apr 14.

45.

The evolving genomic landscape of recurrent gliomas.

Ampie L, Kusne Y, Sanai N.

World Neurosurg. 2015 May;83(5):722-3. doi: 10.1016/j.wneu.2015.03.004. Epub 2015 Mar 10. No abstract available.

PMID:
25765925
46.

Postnatal growth of the human pons: a morphometric and immunohistochemical analysis.

Tate MC, Lindquist RA, Nguyen T, Sanai N, Barkovich AJ, Huang EJ, Rowitch DH, Alvarez-Buylla A.

J Comp Neurol. 2015 Feb 15;523(3):449-62. doi: 10.1002/cne.23690. Epub 2014 Dec 2.

47.

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Kusne Y, Carrera-Silva EA, Perry AS, Rushing EJ, Mandell EK, Dietrich JD, Errasti AE, Gibbs D, Berens ME, Loftus JC, Hulme C, Yang W, Lu Z, Aldape K, Sanai N, Rothlin CV, Ghosh S.

Sci Signal. 2014 Aug 12;7(338):ra75. doi: 10.1126/scisignal.2005196.

48.

Trends in fluorescence image-guided surgery for gliomas.

Liu JT, Meza D, Sanai N.

Neurosurgery. 2014 Jul;75(1):61-71. doi: 10.1227/NEU.0000000000000344. Review.

49.

Predictors of functional recovery in adults with posterior fossa ependymomas.

Mirzadeh Z, Bina R, Kusne Y, Coons SW, Spetzler RF, Sanai N.

J Neurosurg. 2014 May;120(5):1063-8. doi: 10.3171/2014.1.JNS131590. Epub 2014 Feb 28.

PMID:
24579660
50.

An extent of resection threshold for recurrent glioblastoma and its risk for neurological morbidity.

Oppenlander ME, Wolf AB, Snyder LA, Bina R, Wilson JR, Coons SW, Ashby LS, Brachman D, Nakaji P, Porter RW, Smith KA, Spetzler RF, Sanai N.

J Neurosurg. 2014 Apr;120(4):846-53. doi: 10.3171/2013.12.JNS13184. Epub 2014 Jan 31.

PMID:
24484232

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