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Items: 35


Transfer dynamics of Tn6648, a composite integrative conjugative element generated by tandem accretion of Tn5801 and Tn6647 in Enterococcus faecalis.

León-Sampedro R, Fernández-de-Bobadilla MD, San Millán Á, Baquero F, Coque TM.

J Antimicrob Chemother. 2019 Jun 21. pii: dkz239. doi: 10.1093/jac/dkz239. [Epub ahead of print]


Two-degrees-of-freedom PI2D controller for precise nanopositioning in the presence of hardware-induced constant time delay.

San-Millan A, Feliu-Batlle V, Aphale SS.

ISA Trans. 2019 Jan 30. pii: S0019-0578(19)30040-0. doi: 10.1016/j.isatra.2019.01.028. [Epub ahead of print]


Integrative analysis of fitness and metabolic effects of plasmids in Pseudomonas aeruginosa PAO1.

San Millan A, Toll-Riera M, Qi Q, Betts A, Hopkinson RJ, McCullagh J, MacLean RC.

ISME J. 2018 Dec;12(12):3014-3024. doi: 10.1038/s41396-018-0224-8. Epub 2018 Aug 10.


Evolution of Plasmid-Mediated Antibiotic Resistance in the Clinical Context.

San Millan A.

Trends Microbiol. 2018 Dec;26(12):978-985. doi: 10.1016/j.tim.2018.06.007. Epub 2018 Jul 23. Review.


Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance.

Escudero JA, MacLean RC, San Millan A.

J Vis Exp. 2018 May 2;(135). doi: 10.3791/57386.


Multicopy plasmids allow bacteria to escape from fitness trade-offs during evolutionary innovation.

Rodriguez-Beltran J, Hernandez-Beltran JCR, DelaFuente J, Escudero JA, Fuentes-Hernandez A, MacLean RC, Peña-Miller R, San Millan A.

Nat Ecol Evol. 2018 May;2(5):873-881. doi: 10.1038/s41559-018-0529-z. Epub 2018 Apr 9.


PCR-Based Analysis of ColE1 Plasmids in Clinical Isolates and Metagenomic Samples Reveals Their Importance as Gene Capture Platforms.

Ares-Arroyo M, Bernabe-Balas C, Santos-Lopez A, Baquero MR, Prasad KN, Cid D, Martin-Espada C, San Millan A, Gonzalez-Zorn B.

Front Microbiol. 2018 Mar 16;9:469. doi: 10.3389/fmicb.2018.00469. eCollection 2018.


Fractional order implementation of Integral Resonant Control - A nanopositioning application.

San-Millan A, Feliu-Batlle V, Aphale SS.

ISA Trans. 2018 Nov;82:223-231. doi: 10.1016/j.isatra.2017.09.022. Epub 2017 Oct 4.


Fitness Costs of Plasmids: a Limit to Plasmid Transmission.

San Millan A, MacLean RC.

Microbiol Spectr. 2017 Sep;5(5). doi: 10.1128/microbiolspec.MTBP-0016-2017. Review.


Multicopy plasmids potentiate the evolution of antibiotic resistance in bacteria.

San Millan A, Escudero JA, Gifford DR, Mazel D, MacLean RC.

Nat Ecol Evol. 2016 Nov 7;1(1):10. doi: 10.1038/s41559-016-0010.


Wiener-Hopf optimal control of a hydraulic canal prototype with fractional order dynamics.

Feliu-Batlle V, Feliu-Talegón D, San-Millan A, Rivas-Pérez R.

ISA Trans. 2018 Nov;82:130-144. doi: 10.1016/j.isatra.2017.06.012. Epub 2017 Jun 27.


A Naturally Occurring Single Nucleotide Polymorphism in a Multicopy Plasmid Produces a Reversible Increase in Antibiotic Resistance.

Santos-Lopez A, Bernabe-Balas C, Ares-Arroyo M, Ortega-Huedo R, Hoefer A, San Millan A, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2017 Jan 24;61(2). pii: e01735-16. doi: 10.1128/AAC.01735-16. Print 2017 Feb.


[Quantitative gait analysis in patients with advanced Parkinson's disease].

Villadoniga M, San Millan A, Cabanes-Martinez L, Aviles-Olmos I, Del Alamo-De Pedro M, Regidor I.

Rev Neurol. 2016 Aug 1;63(3):97-102. Spanish.


The Genomic Basis of Evolutionary Innovation in Pseudomonas aeruginosa.

Toll-Riera M, San Millan A, Wagner A, MacLean RC.

PLoS Genet. 2016 May 5;12(5):e1006005. doi: 10.1371/journal.pgen.1006005. eCollection 2016 May.


Evaluating the effect of horizontal transmission on the stability of plasmids under different selection regimes.

Peña-Miller R, Rodríguez-González R, MacLean RC, San Millan A.

Mob Genet Elements. 2015 May 21;5(3):1-5. eCollection 2015 May-Jun.


Microbial Evolution: Towards Resolving the Plasmid Paradox.

MacLean RC, San Millan A.

Curr Biol. 2015 Aug 31;25(17):R764-7. doi: 10.1016/j.cub.2015.07.006.


Sequencing of plasmids pAMBL1 and pAMBL2 from Pseudomonas aeruginosa reveals a blaVIM-1 amplification causing high-level carbapenem resistance.

San Millan A, Toll-Riera M, Escudero JA, Cantón R, Coque TM, MacLean RC.

J Antimicrob Chemother. 2015 Nov;70(11):3000-3. doi: 10.1093/jac/dkv222. Epub 2015 Jul 24.


Interactions between horizontally acquired genes create a fitness cost in Pseudomonas aeruginosa.

San Millan A, Toll-Riera M, Qi Q, MacLean RC.

Nat Commun. 2015 Apr 21;6:6845. doi: 10.1038/ncomms7845.


Small-plasmid-mediated antibiotic resistance is enhanced by increases in plasmid copy number and bacterial fitness.

San Millan A, Santos-Lopez A, Ortega-Huedo R, Bernabe-Balas C, Kennedy SP, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2015;59(6):3335-41. doi: 10.1128/AAC.00235-15. Epub 2015 Mar 30.


Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids.

San Millan A, Peña-Miller R, Toll-Riera M, Halbert ZV, McLean AR, Cooper BS, MacLean RC.

Nat Commun. 2014 Oct 10;5:5208. doi: 10.1038/ncomms6208.


Culturable aerobic and facultative bacteria from the gut of the polyphagic dung beetle Thorectes lusitanicus.

Hernández N, Escudero JA, San Millán Á, González-Zorn B, Lobo JM, Verdú JR, Suárez M.

Insect Sci. 2015 Apr;22(2):178-90. doi: 10.1111/1744-7917.12094. Epub 2014 Apr 30.


Positive epistasis between co-infecting plasmids promotes plasmid survival in bacterial populations.

San Millan A, Heilbron K, MacLean RC.

ISME J. 2014 Mar;8(3):601-12. doi: 10.1038/ismej.2013.182. Epub 2013 Oct 24.


SatR is a repressor of fluoroquinolone efflux pump SatAB.

Escudero JA, San Millan A, Montero N, Gutierrez B, Ovejero CM, Carrilero L, González-Zorn B.

Antimicrob Agents Chemother. 2013 Jul;57(7):3430-3. doi: 10.1128/AAC.00515-13. Epub 2013 May 6.


Molecular organization of small plasmids bearing blaTEM-1 and conferring resistance to β-lactams in Haemophilus influenzae.

Søndergaard A, San Millan A, Santos-Lopez A, Nielsen SM, Gonzalez-Zorn B, Nørskov-Lauritsen N.

Antimicrob Agents Chemother. 2012 Sep;56(9):4958-60. doi: 10.1128/AAC.00408-12. Epub 2012 Jun 25.


Fitness cost and interference of Arm/Rmt aminoglycoside resistance with the RsmF housekeeping methyltransferases.

Gutierrez B, Escudero JA, San Millan A, Hidalgo L, Carrilero L, Ovejero CM, Santos-Lopez A, Thomas-Lopez D, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2012 May;56(5):2335-41. doi: 10.1128/AAC.06066-11. Epub 2012 Feb 13.


Fluoroquinolone efflux in Streptococcus suis is mediated by SatAB and not by SmrA.

Escudero JA, San Millan A, Gutierrez B, Hidalgo L, La Ragione RM, AbuOun M, Galimand M, Ferrándiz MJ, Domínguez L, de la Campa AG, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2011 Dec;55(12):5850-60. doi: 10.1128/AAC.00498-11. Epub 2011 Sep 19.


ArmA methyltransferase in a monophasic Salmonella enterica isolate from food.

Granier SA, Hidalgo L, San Millan A, Escudero JA, Gutierrez B, Brisabois A, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2011 Nov;55(11):5262-6. doi: 10.1128/AAC.00308-11. Epub 2011 Aug 22.


Plasmid-borne 16S rRNA methylase ArmA in aminoglycoside-resistant Klebsiella pneumoniae in Poland.

Zacharczuk K, Piekarska K, Szych J, Jagielski M, Hidalgo L, San Millán A, Gutiérrez B, Rastawicki W, González-Zorn B, Gierczynski R.

J Med Microbiol. 2011 Sep;60(Pt 9):1306-11. doi: 10.1099/jmm.0.024026-0. Epub 2011 Jan 20.


Contribution of ROB-1 and PBP3 mutations to the resistance phenotype of a β-lactamase-positive amoxicillin/clavulanic acid-resistant Haemophilus influenzae carrying plasmid pB1000 in Italy.

San Millan A, Giufré M, Escudero JA, Hidalgo L, Gutierrez B, Cerquetti M, Gonzalez-Zorn B.

J Antimicrob Chemother. 2011 Jan;66(1):96-9. doi: 10.1093/jac/dkq392. Epub 2010 Oct 26.


Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination.

San Millan A, Garcia-Cobos S, Escudero JA, Hidalgo L, Gutierrez B, Carrilero L, Campos J, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2010 Apr;54(4):1506-11. doi: 10.1128/AAC.01489-09. Epub 2010 Jan 19.


Novel genetic environment of qnrB2 associated with TEM-1 and SHV-12 on pB1004, an IncHI2 plasmid, in Salmonella Bredeney BB1047 from Spain.

Gutierrez B, Herrera-Leon S, Escudero JA, Hidalgo L, Gonzalez-Sanz R, Arroyo M, San Millan A, Echeita MA, Gonzalez-Zorn B.

J Antimicrob Chemother. 2009 Dec;64(6):1334-6. doi: 10.1093/jac/dkp340. Epub 2009 Sep 22. No abstract available.


Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids.

San Millan A, Escudero JA, Gutierrez B, Hidalgo L, Garcia N, Llagostera M, Dominguez L, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2009 Aug;53(8):3399-404. doi: 10.1128/AAC.01522-08. Epub 2009 Jun 15.


VanB-type Enterococcus faecium clinical isolate successively inducibly resistant to, dependent on, and constitutively resistant to vancomycin.

San Millan A, Depardieu F, Godreuil S, Courvalin P.

Antimicrob Agents Chemother. 2009 May;53(5):1974-82. doi: 10.1128/AAC.00034-09. Epub 2009 Mar 9.


Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1.

San Millan A, Escudero JA, Catalan A, Nieto S, Farelo F, Gibert M, Moreno MA, Dominguez L, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2007 Jun;51(6):2260-4. Epub 2007 Apr 16.


First characterization of fluoroquinolone resistance in Streptococcus suis.

Escudero JA, San Millan A, Catalan A, de la Campa AG, Rivero E, Lopez G, Dominguez L, Moreno MA, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2007 Feb;51(2):777-82. Epub 2006 Nov 20.

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