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Items: 1 to 50 of 117

1.

Tamoxifen-Induced Gastric Injury: Effects of Dose and Method of Administration.

Keeley TM, Horita N, Samuelson LC.

Cell Mol Gastroenterol Hepatol. 2019 Jun 21. pii: S2352-345X(19)30086-4. doi: 10.1016/j.jcmgh.2019.06.007. [Epub ahead of print] No abstract available.

2.

Notch and mTOR Signaling Pathways Promote Human Gastric Cancer Cell Proliferation.

Hibdon ES, Razumilava N, Keeley TM, Wong G, Solanki S, Shah YM, Samuelson LC.

Neoplasia. 2019 Jul;21(7):702-712. doi: 10.1016/j.neo.2019.05.002. Epub 2019 May 24.

3.

Generation of Organoids from Mouse Extrahepatic Bile Ducts.

Shiota J, Zaki NHM, Merchant JL, Samuelson LC, Razumilava N.

J Vis Exp. 2019 Apr 23;(146). doi: 10.3791/59544.

PMID:
31081815
4.

Organoids and Engineered Organ Systems.

Samuelson LC, Lynch JP.

Cell Mol Gastroenterol Hepatol. 2019;7(3):679-681. doi: 10.1016/j.jcmgh.2019.02.005. Epub 2019 Mar 2. No abstract available.

5.

Hedgehog Signaling Modulates Interleukin-33-Dependent Extrahepatic Bile Duct Cell Proliferation in Mice.

Razumilava N, Shiota J, Mohamad Zaki NH, Ocadiz-Ruiz R, Cieslak CM, Zakharia K, Allen BL, Gores GJ, Samuelson LC, Merchant JL.

Hepatol Commun. 2018 Dec 11;3(2):277-292. doi: 10.1002/hep4.1295. eCollection 2019 Feb.

6.

Genome Toxicity and Impaired Stem Cell Function after Conditional Activation of CreERT2 in the Intestine.

Bohin N, Carlson EA, Samuelson LC.

Stem Cell Reports. 2018 Dec 11;11(6):1337-1346. doi: 10.1016/j.stemcr.2018.10.014. Epub 2018 Nov 15.

7.

Past Questions and Current Understanding About Gastric Cancer.

Mills JC, Samuelson LC.

Gastroenterology. 2018 Oct;155(4):939-944. doi: 10.1053/j.gastro.2018.06.044. Epub 2018 Jun 30. No abstract available.

PMID:
29964037
8.

Regulation of Gastric Lgr5+ve Cell Homeostasis by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli.

Ye W, Takabayashi H, Yang Y, Mao M, Hibdon ES, Samuelson LC, Eaton KA, Todisco A.

Cell Mol Gastroenterol Hepatol. 2018 Jan 31;5(4):523-538. doi: 10.1016/j.jcmgh.2018.01.007. eCollection 2018.

9.

Debate over the identity of an intestinal niche-cell population settled.

Samuelson LC.

Nature. 2018 Jun;558(7710):380-381. doi: 10.1038/d41586-018-05281-z. No abstract available.

PMID:
29907820
10.

Identification, isolation and characterization of human LGR5-positive colon adenoma cells.

Dame MK, Attili D, McClintock SD, Dedhia PH, Ouillette P, Hardt O, Chin AM, Xue X, Laliberte J, Katz EL, Newsome GM, Hill DR, Miller AJ, Tsai YH, Agorku D, Altheim CH, Bosio A, Simon B, Samuelson LC, Stoerker JA, Appelman HD, Varani J, Wicha MS, Brenner DE, Shah YM, Spence JR, Colacino JA.

Development. 2018 Mar 14;145(6). pii: dev153049. doi: 10.1242/dev.153049.

11.

Cellular Plasticity in the Stomach: Insights Into the Cellular Origin of Gastric Metaplasia.

Hibdon ES, Samuelson LC.

Gastroenterology. 2018 Mar;154(4):801-803. doi: 10.1053/j.gastro.2018.02.001. Epub 2018 Feb 6. No abstract available.

PMID:
29425924
12.

Indian Hedgehog Suppresses Intestinal Inflammation.

Razumilava N, Gumucio DL, Samuelson LC, Shah YM, Nusrat A, Merchant JL.

Cell Mol Gastroenterol Hepatol. 2017 Oct 31;5(1):63-64. doi: 10.1016/j.jcmgh.2017.10.003. eCollection 2018. No abstract available.

13.

Live imaging analysis of human gastric epithelial spheroids reveals spontaneous rupture, rotation and fusion events.

Sebrell TA, Sidar B, Bruns R, Wilkinson RA, Wiedenheft B, Taylor PJ, Perrino BA, Samuelson LC, Wilking JN, Bimczok D.

Cell Tissue Res. 2018 Feb;371(2):293-307. doi: 10.1007/s00441-017-2726-5. Epub 2017 Nov 25.

14.

Lrig1+ gastric isthmal progenitor cells restore normal gastric lineage cells during damage recovery in adult mouse stomach.

Choi E, Lantz TL, Vlacich G, Keeley TM, Samuelson LC, Coffey RJ, Goldenring JR, Powell AE.

Gut. 2018 Sep;67(9):1595-1605. doi: 10.1136/gutjnl-2017-313874. Epub 2017 Aug 16.

15.

Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca2+ Efflux Channel in the Tubulovesicle.

Sahoo N, Gu M, Zhang X, Raval N, Yang J, Bekier M, Calvo R, Patnaik S, Wang W, King G, Samie M, Gao Q, Sahoo S, Sundaresan S, Keeley TM, Wang Y, Marugan J, Ferrer M, Samuelson LC, Merchant JL, Xu H.

Dev Cell. 2017 May 8;41(3):262-273.e6. doi: 10.1016/j.devcel.2017.04.003.

16.

Notch as a Driver of Gastric Epithelial Cell Proliferation.

Demitrack ES, Samuelson LC.

Cell Mol Gastroenterol Hepatol. 2017 Feb 14;3(3):323-330. doi: 10.1016/j.jcmgh.2017.01.012. eCollection 2017 May. Review.

17.

Gastrin induces parathyroid hormone-like hormone expression in gastric parietal cells.

Al Menhali A, Keeley TM, Demitrack ES, Samuelson LC.

Am J Physiol Gastrointest Liver Physiol. 2017 Jun 1;312(6):G649-G657. doi: 10.1152/ajpgi.00366.2016. Epub 2017 Apr 13.

18.

NOTCH1 and NOTCH2 regulate epithelial cell proliferation in mouse and human gastric corpus.

Demitrack ES, Gifford GB, Keeley TM, Horita N, Todisco A, Turgeon DK, Siebel CW, Samuelson LC.

Am J Physiol Gastrointest Liver Physiol. 2017 Feb 1;312(2):G133-G144. doi: 10.1152/ajpgi.00325.2016. Epub 2016 Dec 8.

19.

Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis.

Gifford GB, Demitrack ES, Keeley TM, Tam A, La Cunza N, Dedhia PH, Spence JR, Simeone DM, Saotome I, Louvi A, Siebel CW, Samuelson LC.

Gut. 2017 Jun;66(6):1001-1011. doi: 10.1136/gutjnl-2015-310811. Epub 2016 Mar 1.

20.

Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways.

Syu LJ, Zhao X, Zhang Y, Grachtchouk M, Demitrack E, Ermilov A, Wilbert DM, Zheng X, Kaatz A, Greenson JK, Gumucio DL, Merchant JL, di Magliano MP, Samuelson LC, Dlugosz AA.

Oncotarget. 2016 Mar 1;7(9):10255-70. doi: 10.18632/oncotarget.7182.

21.

Notch regulation of gastrointestinal stem cells.

Demitrack ES, Samuelson LC.

J Physiol. 2016 Sep 1;594(17):4791-803. doi: 10.1113/JP271667. Epub 2016 Jun 26. Review.

22.

The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia.

Pinnell N, Yan R, Cho HJ, Keeley T, Murai MJ, Liu Y, Alarcon AS, Qin J, Wang Q, Kuick R, Elenitoba-Johnson KS, Maillard I, Samuelson LC, Cierpicki T, Chiang MY.

Immunity. 2015 Nov 17;43(5):870-83. doi: 10.1016/j.immuni.2015.10.007. Epub 2015 Oct 27.

23.

APSselect: Year One a Success!

Metzger JM, Samuelson LC.

Physiologist. 2015 Jul;58(4):188-90. No abstract available.

PMID:
26434156
24.

Regulation of gastric epithelial cell homeostasis by gastrin and bone morphogenetic protein signaling.

Todisco A, Mao M, Keeley TM, Ye W, Samuelson LC, Eaton KA.

Physiol Rep. 2015 Aug;3(8). pii: e12501. doi: 10.14814/phy2.12501.

25.

Notch signaling regulates gastric antral LGR5 stem cell function.

Demitrack ES, Gifford GB, Keeley TM, Carulli AJ, VanDussen KL, Thomas D, Giordano TJ, Liu Z, Kopan R, Samuelson LC.

EMBO J. 2015 Oct 14;34(20):2522-36. doi: 10.15252/embj.201490583. Epub 2015 Aug 12.

26.

Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration.

Carulli AJ, Keeley TM, Demitrack ES, Chung J, Maillard I, Samuelson LC.

Dev Biol. 2015 Jun 1;402(1):98-108. doi: 10.1016/j.ydbio.2015.03.012. Epub 2015 Mar 30.

27.

ADAM10 regulates Notch function in intestinal stem cells of mice.

Tsai YH, VanDussen KL, Sawey ET, Wade AW, Kasper C, Rakshit S, Bhatt RG, Stoeck A, Maillard I, Crawford HC, Samuelson LC, Dempsey PJ.

Gastroenterology. 2014 Oct;147(4):822-834.e13. doi: 10.1053/j.gastro.2014.07.003. Epub 2014 Jul 16.

28.

Unraveling intestinal stem cell behavior with models of crypt dynamics.

Carulli AJ, Samuelson LC, Schnell S.

Integr Biol (Camb). 2014 Mar;6(3):243-57. doi: 10.1039/c3ib40163d. Epub 2014 Jan 30. Review.

29.

Blockade of individual Notch ligands and receptors controls graft-versus-host disease.

Tran IT, Sandy AR, Carulli AJ, Ebens C, Chung J, Shan GT, Radojcic V, Friedman A, Gridley T, Shelton A, Reddy P, Samuelson LC, Yan M, Siebel CW, Maillard I.

J Clin Invest. 2013 Apr;123(4):1590-604.

30.

Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion.

Worthington JJ, Samuelson LC, Grencis RK, McLaughlin JT.

PLoS Pathog. 2013 Jan;9(1):e1003122. doi: 10.1371/journal.ppat.1003122. Epub 2013 Jan 17.

31.

Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.

Syu LJ, El-Zaatari M, Eaton KA, Liu Z, Tetarbe M, Keeley TM, Pero J, Ferris J, Wilbert D, Kaatz A, Zheng X, Qiao X, Grachtchouk M, Gumucio DL, Merchant JL, Samuelson LC, Dlugosz AA.

Am J Pathol. 2012 Dec;181(6):2114-25. doi: 10.1016/j.ajpath.2012.08.017. Epub 2012 Oct 1.

32.

IFNγ contributes to the development of gastric epithelial cell metaplasia in Huntingtin interacting protein 1 related (Hip1r)-deficient mice.

Liu Z, Demitrack ES, Keeley TM, Eaton KA, El-Zaatari M, Merchant JL, Samuelson LC.

Lab Invest. 2012 Jul;92(7):1045-57. doi: 10.1038/labinvest.2012.73. Epub 2012 Apr 23.

33.

Gastric Sonic Hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pylori.

Schumacher MA, Donnelly JM, Engevik AC, Xiao C, Yang L, Kenny S, Varro A, Hollande F, Samuelson LC, Zavros Y.

Gastroenterology. 2012 May;142(5):1150-1159.e6. doi: 10.1053/j.gastro.2012.01.029. Epub 2012 Jan 25.

34.

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.

VanDussen KL, Carulli AJ, Keeley TM, Patel SR, Puthoff BJ, Magness ST, Tran IT, Maillard I, Siebel C, Kolterud Å, Grosse AS, Gumucio DL, Ernst SA, Tsai YH, Dempsey PJ, Samuelson LC.

Development. 2012 Feb;139(3):488-97. doi: 10.1242/dev.070763. Epub 2011 Dec 21.

35.

Gastric tuft cells express DCLK1 and are expanded in hyperplasia.

Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL.

Histochem Cell Biol. 2011 Aug;136(2):191-204. doi: 10.1007/s00418-011-0831-1. Epub 2011 Jun 18.

36.

Overexpression of sICAM-1 in the alveolar epithelial space results in an exaggerated inflammatory response and early death in Gram negative pneumonia.

Mendez MP, Monroy YK, Du M, Preston AM, Tolle L, Lin Y, VanDussen KL, Samuelson LC, Standiford TJ, Curtis JL, Beck JM, Christensen PJ, Paine R 3rd.

Respir Res. 2011 Jan 19;12:12. doi: 10.1186/1465-9921-12-12.

37.

Bone morphogenetic protein signaling regulates gastric epithelial cell development and proliferation in mice.

Shinohara M, Mao M, Keeley TM, El-Zaatari M, Lee HJ, Eaton KA, Samuelson LC, Merchant JL, Goldenring JR, Todisco A.

Gastroenterology. 2010 Dec;139(6):2050-2060.e2. doi: 10.1053/j.gastro.2010.08.052. Epub 2010 Oct 16.

38.

Cytodifferentiation of the postnatal mouse stomach in normal and Huntingtin-interacting protein 1-related-deficient mice.

Keeley TM, Samuelson LC.

Am J Physiol Gastrointest Liver Physiol. 2010 Dec;299(6):G1241-51. doi: 10.1152/ajpgi.00239.2010. Epub 2010 Sep 2.

39.

Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate.

VanDussen KL, Samuelson LC.

Dev Biol. 2010 Oct 15;346(2):215-23. doi: 10.1016/j.ydbio.2010.07.026. Epub 2010 Aug 4.

40.

Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival.

Lavine JA, Raess PW, Stapleton DS, Rabaglia ME, Suhonen JI, Schueler KL, Koltes JE, Dawson JA, Yandell BS, Samuelson LC, Beinfeld MC, Davis DB, Hellerstein MK, Keller MP, Attie AD.

Endocrinology. 2010 Aug;151(8):3577-88. doi: 10.1210/en.2010-0233. Epub 2010 Jun 9.

41.

Cholecystokinin knockout mice are resistant to high-fat diet-induced obesity.

Lo CM, King A, Samuelson LC, Kindel TL, Rider T, Jandacek RJ, Raybould HE, Woods SC, Tso P.

Gastroenterology. 2010 May;138(5):1997-2005. doi: 10.1053/j.gastro.2010.01.044. Epub 2010 Feb 1.

42.

Effect of gallbladder hypomotility on cholesterol crystallization and growth in CCK-deficient mice.

Wang HH, Portincasa P, Liu M, Tso P, Samuelson LC, Wang DQ.

Biochim Biophys Acta. 2010 Feb;1801(2):138-46. doi: 10.1016/j.bbalip.2009.10.003. Epub 2009 Oct 22.

43.

Hip1r is expressed in gastric parietal cells and is required for tubulovesicle formation and cell survival in mice.

Jain RN, Al-Menhali AA, Keeley TM, Ren J, El-Zaatari M, Chen X, Merchant JL, Ross TS, Chew CS, Samuelson LC.

J Clin Invest. 2008 Jul;118(7):2459-70. doi: 10.1172/JCI33569.

44.

Characterization of mice lacking the gene for cholecystokinin.

Lo CM, Samuelson LC, Chambers JB, King A, Heiman J, Jandacek RJ, Sakai RR, Benoit SC, Raybould HE, Woods SC, Tso P.

Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R803-10. Epub 2007 Dec 26.

45.

Prospective identification of a multilineage progenitor in murine stomach epithelium.

Qiao XT, Ziel JW, McKimpson W, Madison BB, Todisco A, Merchant JL, Samuelson LC, Gumucio DL.

Gastroenterology. 2007 Dec;133(6):1989-98.

46.

Reduced pepsin A processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation.

Zavros Y, Waghray M, Tessier A, Bai L, Todisco A, L Gumucio D, Samuelson LC, Dlugosz A, Merchant JL.

J Biol Chem. 2007 Nov 16;282(46):33265-74. Epub 2007 Sep 14.

47.

Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line.

Hughes ED, Qu YY, Genik SJ, Lyons RH, Pacheco CD, Lieberman AP, Samuelson LC, Nasonkin IO, Camper SA, Van Keuren ML, Saunders TL.

Mamm Genome. 2007 Aug;18(8):549-58. Epub 2007 Sep 9.

PMID:
17828574
48.

Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate.

López-Díaz L, Jain RN, Keeley TM, VanDussen KL, Brunkan CS, Gumucio DL, Samuelson LC.

Dev Biol. 2007 Sep 15;309(2):298-305. Epub 2007 Jul 24.

49.

Transcriptional profiling of gastrin-regulated genes in mouse stomach.

Jain RN, Samuelson LC.

Physiol Genomics. 2007 Mar 14;29(1):1-12. Epub 2006 Nov 14.

PMID:
17105752
50.

Differentiation of the gastric mucosa. II. Role of gastrin in gastric epithelial cell proliferation and maturation.

Jain RN, Samuelson LC.

Am J Physiol Gastrointest Liver Physiol. 2006 Nov;291(5):G762-5. Review.

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