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Items: 23


Surgical induction of posttraumatic osteoarthritis in the mouse.

Hamada D, Sampson ER, Maynard RD, Zuscik MJ.

Methods Mol Biol. 2014;1130:61-72. doi: 10.1007/978-1-62703-989-5_5.


MMP13 is a critical target gene during the progression of osteoarthritis.

Wang M, Sampson ER, Jin H, Li J, Ke QH, Im HJ, Chen D.

Arthritis Res Ther. 2013 Jan 8;15(1):R5. doi: 10.1186/ar4133.


Gene signature critical to cancer phenotype as a paradigm for anticancer drug discovery.

Sampson ER, McMurray HR, Hassane DC, Newman L, Salzman P, Jordan CT, Land H.

Oncogene. 2013 Aug 15;32(33):3809-18. doi: 10.1038/onc.2012.389. Epub 2012 Sep 10.


Lead induces an osteoarthritis-like phenotype in articular chondrocytes through disruption of TGF-β signaling.

Holz JD, Beier E, Sheu TJ, Ubayawardena R, Wang M, Sampson ER, Rosier RN, Zuscik M, Puzas JE.

J Orthop Res. 2012 Nov;30(11):1760-6. doi: 10.1002/jor.22117. Epub 2012 Apr 19.


Ski inhibits TGF-β/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes.

Kim KO, Sampson ER, Maynard RD, O'Keefe RJ, Chen D, Drissi H, Rosier RN, Hilton MJ, Zuscik MJ.

J Cell Biochem. 2012 Jun;113(6):2156-66. doi: 10.1002/jcb.24089.


Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue.

Wang M, Tang D, Shu B, Wang B, Jin H, Hao S, Dresser KA, Shen J, Im HJ, Sampson ER, Rubery PT, Zuscik MJ, Schwarz EM, O'Keefe RJ, Wang Y, Chen D.

Arthritis Rheum. 2012 Aug;64(8):2611-23. doi: 10.1002/art.34469.


High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury.

Mooney RA, Sampson ER, Lerea J, Rosier RN, Zuscik MJ.

Arthritis Res Ther. 2011;13(6):R198. doi: 10.1186/ar3529. Epub 2011 Dec 7.


Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis.

Sampson ER, Hilton MJ, Tian Y, Chen D, Schwarz EM, Mooney RA, Bukata SV, O'Keefe RJ, Awad H, Puzas JE, Rosier RN, Zuscik MJ.

Sci Transl Med. 2011 Sep 21;3(101):101ra93. doi: 10.1126/scitranslmed.3002214.


Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression.

Xie C, Schwarz EM, Sampson ER, Dhillon RS, Li D, O'Keefe RJ, Tyler W.

J Orthop Res. 2012 Feb;30(2):325-33. doi: 10.1002/jor.21500. Epub 2011 Aug 1.


Establishment of an index with increased sensitivity for assessing murine arthritis.

Sampson ER, Beck CA, Ketz J, Canary KL, Hilton MJ, Awad H, Schwarz EM, Chen D, O'Keefe RJ, Rosier RN, Zuscik MJ.

J Orthop Res. 2011 Aug;29(8):1145-51. doi: 10.1002/jor.21368. Epub 2011 Mar 3.


The orally bioavailable met inhibitor PF-2341066 inhibits osteosarcoma growth and osteolysis/matrix production in a xenograft model.

Sampson ER, Martin BA, Morris AE, Xie C, Schwarz EM, O'Keefe RJ, Rosier RN.

J Bone Miner Res. 2011 Jun;26(6):1283-94. doi: 10.1002/jbmr.336.


The histone deacetylase inhibitor vorinostat selectively sensitizes fibrosarcoma cells to chemotherapy.

Sampson ER, Amin V, Schwarz EM, O'Keefe RJ, Rosier RN.

J Orthop Res. 2011 Apr;29(4):623-32. doi: 10.1002/jor.21274. Epub 2010 Oct 18.


Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis.

Li TF, Gao L, Sheu TJ, Sampson ER, Flick LM, Konttinen YT, Chen D, Schwarz EM, Zuscik MJ, Jonason JH, O'Keefe RJ.

Arthritis Rheum. 2010 Aug;62(8):2359-69. doi: 10.1002/art.27537.


Smurf2 induces degradation of GSK-3beta and upregulates beta-catenin in chondrocytes: a potential mechanism for Smurf2-induced degeneration of articular cartilage.

Wu Q, Huang JH, Sampson ER, Kim KO, Zuscik MJ, O'Keefe RJ, Chen D, Rosier RN.

Exp Cell Res. 2009 Aug 15;315(14):2386-98. doi: 10.1016/j.yexcr.2009.05.019. Epub 2009 May 27.


Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice.

Wu Q, Kim KO, Sampson ER, Chen D, Awad H, O'Brien T, Puzas JE, Drissi H, Schwarz EM, O'Keefe RJ, Zuscik MJ, Rosier RN.

Arthritis Rheum. 2008 Oct;58(10):3132-44. doi: 10.1002/art.23946.


Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype.

McMurray HR, Sampson ER, Compitello G, Kinsey C, Newman L, Smith B, Chen SR, Klebanov L, Salzman P, Yakovlev A, Land H.

Nature. 2008 Jun 19;453(7198):1112-6. doi: 10.1038/nature06973. Epub 2008 May 25.


Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer.

Hu YC, Yeh S, Yeh SD, Sampson ER, Huang J, Li P, Hsu CL, Ting HJ, Lin HK, Wang L, Kim E, Ni J, Chang C.

J Biol Chem. 2004 Aug 6;279(32):33438-46. Epub 2004 May 27.


Mutations in the helix 3 region of the androgen receptor abrogate ARA70 promotion of 17beta-estradiol-induced androgen receptor transactivation.

Thin TH, Kim E, Yeh S, Sampson ER, Chen YT, Collins LL, Basavappa R, Chang C.

J Biol Chem. 2002 Sep 27;277(39):36499-508. Epub 2002 Jun 14.


Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator.

Wang X, Yang Y, Guo X, Sampson ER, Hsu CL, Tsai MY, Yeh S, Wu G, Guo Y, Chang C.

J Biol Chem. 2002 May 3;277(18):15426-31. Epub 2002 Feb 20.


Identification and characterization of androgen receptor associated coregulators in prostate cancer cells.

Sampson ER, Yeh SY, Chang HC, Tsai MY, Wang X, Ting HJ, Chang C.

J Biol Regul Homeost Agents. 2001 Apr-Jun;15(2):123-9. Review.


Functional analysis of androgen receptor N-terminal and ligand binding domain interacting coregulators in prostate cancer.

Yeh S, Sampson ER, Lee DK, Kim E, Hsu CL, Chen YL, Chang HC, Altuwaijri S, Huang KE, Chang C.

J Formos Med Assoc. 2000 Dec;99(12):885-94. Review.


Localization of the tandem pore domain K+ channel TASK-1 in the rat central nervous system.

Kindler CH, Pietruck C, Yost CS, Sampson ER, Gray AT.

Brain Res Mol Brain Res. 2000 Aug 14;80(1):99-108.


Assignment of KCNK6 encoding the human weak inward rectifier potassium channel TWIK-2 to chromosome band 19q13.1 by radiation hybrid mapping.

Gray AT, Kindler CH, Sampson ER, Yost CS.

Cytogenet Cell Genet. 1999;84(3-4):190-1. No abstract available.


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