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Items: 43

1.

Early induction of senescence and immortalization in PGC-1α-deficient mouse embryonic fibroblasts.

Prieto I, Zambrano A, Laso J, Aranda A, Samper E, Monsalve M.

Free Radic Biol Med. 2019 Jul;138:23-32. doi: 10.1016/j.freeradbiomed.2019.04.015. Epub 2019 Apr 25.

PMID:
31029787
2.

Zeb1 in Stromal Myofibroblasts Promotes Kras-Driven Development of Pancreatic Cancer.

Sangrador I, Molero X, Campbell F, Franch-Expósito S, Rovira-Rigau M, Samper E, Domínguez-Fraile M, Fillat C, Castells A, Vaquero EC.

Cancer Res. 2018 May 15;78(10):2624-2637. doi: 10.1158/0008-5472.CAN-17-1882. Epub 2018 Feb 28.

3.

Human adipose tissue-derived stromal cells in combination with exogenous stimuli facilitate three-dimensional network formation of human endothelial cells derived from various sources.

Manikowski D, Andrée B, Samper E, Saint-Marc C, Olmer R, Vogt P, Strauß S, Haverich A, Hilfiker A.

Vascul Pharmacol. 2018 Jul;106:28-36. doi: 10.1016/j.vph.2018.02.003. Epub 2018 Feb 13.

PMID:
29452238
4.

Rare germline copy number variants in colorectal cancer predisposition characterized by exome sequencing analysis.

Franch-Expósito S, Esteban-Jurado C, Garre P, Quintanilla I, Duran-Sanchon S, Díaz-Gay M, Bonjoch L, Cuatrecasas M, Samper E, Muñoz J, Ocaña T, Carballal S, López-Cerón M, Castells A; EPICOLON consortium, Vila-Casadesús M, Derdak S, Laurie S, Beltran S, Carvajal J, Bujanda L, Ruiz-Ponte C, Camps J, Gironella M, Lozano JJ, Balaguer F, Cubiella J, Caldés T, Castellví-Bel S.

J Genet Genomics. 2018 Jan 20;45(1):41-45. doi: 10.1016/j.jgg.2017.12.001. Epub 2017 Dec 20. No abstract available.

PMID:
29396139
5.

Polμ deficiency induces moderate shortening of P53-/- mouse lifespan and modifies tumor spectrum.

Escudero B, Herrero D, Torres Y, Cañón S, Molina A, Carmona RM, Suela J, Blanco L, Samper E, Bernad A.

DNA Repair (Amst). 2017 Jun;54:40-45. doi: 10.1016/j.dnarep.2017.04.001. Epub 2017 Apr 10.

PMID:
28460268
6.

Targeted gene therapy and cell reprogramming in Fanconi anemia.

Rio P, Baños R, Lombardo A, Quintana-Bustamante O, Alvarez L, Garate Z, Genovese P, Almarza E, Valeri A, Díez B, Navarro S, Torres Y, Trujillo JP, Murillas R, Segovia JC, Samper E, Surralles J, Gregory PD, Holmes MC, Naldini L, Bueren JA.

EMBO Mol Med. 2014 Jun;6(6):835-48. doi: 10.15252/emmm.201303374. Epub 2014 Apr 6.

7.

Polμ deficiency increases resistance to oxidative damage and delays liver aging.

Escudero B, Lucas D, Albo C, Dhup S, Bacher JW, Sánchez-Muñoz A, Fernández M, Rivera-Torres J, Carmona RM, Fuster E, Carreiro C, Bernad R, González MA, Andrés V, Blanco L, Roche E, Fabregat I, Samper E, Bernad A.

PLoS One. 2014 Apr 1;9(4):e93074. doi: 10.1371/journal.pone.0093074. eCollection 2014.

8.

Generation of iPSCs from genetically corrected Brca2 hypomorphic cells: implications in cell reprogramming and stem cell therapy.

Navarro S, Moleiro V, Molina-Estevez FJ, Lozano ML, Chinchon R, Almarza E, Quintana-Bustamante O, Mostoslavsky G, Maetzig T, Galla M, Heinz N, Schiedlmeier B, Torres Y, Modlich U, Samper E, Río P, Segovia JC, Raya A, Güenechea G, Izpisua-Belmonte JC, Bueren JA.

Stem Cells. 2014 Feb;32(2):436-46. doi: 10.1002/stem.1586.

9.

Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy.

Estrada JC, Torres Y, Benguría A, Dopazo A, Roche E, Carrera-Quintanar L, Pérez RA, Enríquez JA, Torres R, Ramírez JC, Samper E, Bernad A.

Cell Death Dis. 2013 Jun 27;4:e691. doi: 10.1038/cddis.2013.211.

10.

Brief report: impaired cell reprogramming in nonhomologous end joining deficient cells.

Molina-Estevez FJ, Lozano ML, Navarro S, Torres Y, Grabundzija I, Ivics Z, Samper E, Bueren JA, Guenechea G.

Stem Cells. 2013 Aug;31(8):1726-30. doi: 10.1002/stem.1406.

11.

Complement anaphylatoxins C3a and C5a induce a failing regenerative program in cardiac resident cells. Evidence of a role for cardiac resident stem cells other than cardiomyocyte renewal.

Lara-Astiaso D, Izarra A, Estrada JC, Albo C, Moscoso I, Samper E, Moncayo J, Solano A, Bernad A, Díez-Juan A.

Springerplus. 2012 Dec;1(1):63. doi: 10.1186/2193-1801-1-63. Epub 2012 Dec 12.

12.

Increased learning and brain long-term potentiation in aged mice lacking DNA polymerase μ.

Lucas D, Delgado-García JM, Escudero B, Albo C, Aza A, Acín-Pérez R, Torres Y, Moreno P, Enríquez JA, Samper E, Blanco L, Fairén A, Bernad A, Gruart A.

PLoS One. 2013;8(1):e53243. doi: 10.1371/journal.pone.0053243. Epub 2013 Jan 3.

13.

Cardiac cell therapy: boosting mesenchymal stem cells effects.

Samper E, Diez-Juan A, Montero JA, Sepúlveda P.

Stem Cell Rev. 2013 Jun;9(3):266-80. doi: 10.1007/s12015-012-9353-z. Review.

PMID:
22350458
14.

Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis.

Estrada JC, Albo C, Benguría A, Dopazo A, López-Romero P, Carrera-Quintanar L, Roche E, Clemente EP, Enríquez JA, Bernad A, Samper E.

Cell Death Differ. 2012 May;19(5):743-55. doi: 10.1038/cdd.2011.172. Epub 2011 Dec 2.

15.

Assessment of the protective effects of oral tocotrienols in arginine chronic-like pancreatitis.

González AM, Garcia T, Samper E, Rickmann M, Vaquero EC, Molero X.

Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G846-55. doi: 10.1152/ajpgi.00485.2010. Epub 2011 Aug 18.

16.

Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair.

Lucas D, Escudero B, Ligos JM, Segovia JC, Estrada JC, Terrados G, Blanco L, Samper E, Bernad A.

PLoS Genet. 2009 Feb;5(2):e1000389. doi: 10.1371/journal.pgen.1000389. Epub 2009 Feb 20.

17.

Increase in mitochondrial biogenesis, oxidative stress, and glycolysis in murine lymphomas.

Samper E, Morgado L, Estrada JC, Bernad A, Hubbard A, Cadenas S, Melov S.

Free Radic Biol Med. 2009 Feb 1;46(3):387-96. doi: 10.1016/j.freeradbiomed.2008.10.036. Epub 2008 Oct 30.

18.

Dramatic age-related changes in nuclear and genome copy number in the nematode Caenorhabditis elegans.

Golden TR, Beckman KB, Lee AH, Dudek N, Hubbard A, Samper E, Melov S.

Aging Cell. 2007 Apr;6(2):179-88. Epub 2007 Feb 5.

19.

SOCS up-regulation mobilizes autologous stem cells through CXCR4 blockade.

Pello OM, Moreno-Ortiz Mdel C, Rodríguez-Frade JM, Martínez-Muñoz L, Lucas D, Gómez L, Lucas P, Samper E, Aracil M, Martínez C, Bernad A, Mellado M.

Blood. 2006 Dec 1;108(12):3928-37. Epub 2006 Aug 15.

20.

Pol II-expressed shRNA knocks down Sod2 gene expression and causes phenotypes of the gene knockout in mice.

Xia XG, Zhou H, Samper E, Melov S, Xu Z.

PLoS Genet. 2006 Jan;2(1):e10. Epub 2006 Jan 27.

21.

Hyperplasia, reduced E-cadherin expression, and developmental arrest in mammary glands oxidatively stressed by loss of mitochondrial superoxide dismutase.

Parmar H, Melov S, Samper E, Ljung BM, Cunha GR, Benz CC.

Breast. 2005 Aug;14(4):256-63. Epub 2005 Apr 19.

PMID:
16085231
22.

The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine.

Nieto M, Samper E, Fraga MF, González de Buitrago G, Esteller M, Serrano M.

Oncogene. 2004 Jan 22;23(3):735-43.

PMID:
14737108
23.

Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts.

Samper E, Nicholls DG, Melov S.

Aging Cell. 2003 Oct;2(5):277-85. Erratum in: Aging Cell. 2003 Dec;2(6):343.

24.

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts.

Parrinello S, Samper E, Krtolica A, Goldstein J, Melov S, Campisi J.

Nat Cell Biol. 2003 Aug;5(8):741-7. Erratum in: Nat Cell Biol. 2003 Sep;5(9):839.

25.

Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells.

Samper E, Fernández P, Eguía R, Martín-Rivera L, Bernad A, Blasco MA, Aracil M.

Blood. 2002 Apr 15;99(8):2767-75.

26.

Breaks at telomeres and TRF2-independent end fusions in Fanconi anemia.

Callén E, Samper E, Ramírez MJ, Creus A, Marcos R, Ortega JJ, Olivé T, Badell I, Blasco MA, Surrallés J.

Hum Mol Genet. 2002 Feb 15;11(4):439-44.

PMID:
11854176
27.
29.

Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability.

Samper E, Goytisolo FA, Ménissier-de Murcia J, González-Suárez E, Cigudosa JC, de Murcia G, Blasco MA.

J Cell Biol. 2001 Jul 9;154(1):49-60.

30.

Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.

González-Suárez E, Samper E, Ramírez A, Flores JM, Martín-Caballero J, Jorcano JL, Blasco MA.

EMBO J. 2001 Jun 1;20(11):2619-30.

32.

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang.

Samper E, Goytisolo FA, Slijepcevic P, van Buul PP, Blasco MA.

EMBO Rep. 2000 Sep;1(3):244-52.

33.

Telomere length abnormalities in mammalian radiosensitive cells.

McIlrath J, Bouffler SD, Samper E, Cuthbert A, Wojcik A, Szumiel I, Bryant PE, Riches AC, Thompson A, Blasco MA, Newbold RF, Slijepcevic P.

Cancer Res. 2001 Feb 1;61(3):912-5.

34.

Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals.

Goytisolo FA, Samper E, Martín-Caballero J, Finnon P, Herrera E, Flores JM, Bouffler SD, Blasco MA.

J Exp Med. 2000 Dec 4;192(11):1625-36.

35.

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

González-Suárez E, Samper E, Flores JM, Blasco MA.

Nat Genet. 2000 Sep;26(1):114-7.

36.

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres.

Herrera E, Samper E, Martín-Caballero J, Flores JM, Lee HW, Blasco MA.

EMBO J. 1999 Jun 1;18(11):2950-60.

37.
38.

Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice.

Hande MP, Samper E, Lansdorp P, Blasco MA.

J Cell Biol. 1999 Feb 22;144(4):589-601.

39.

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum.

de la Pompa JL, Timmerman LA, Takimoto H, Yoshida H, Elia AJ, Samper E, Potter J, Wakeham A, Marengere L, Langille BL, Crabtree GR, Mak TW.

Nature. 1998 Mar 12;392(6672):182-6.

PMID:
9515963
40.

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.

Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, DePinho RA, Greider CW.

Cell. 1997 Oct 3;91(1):25-34.

41.

Conservation of the Notch signalling pathway in mammalian neurogenesis.

de la Pompa JL, Wakeham A, Correia KM, Samper E, Brown S, Aguilera RJ, Nakano T, Honjo T, Mak TW, Rossant J, Conlon RA.

Development. 1997 Mar;124(6):1139-48.

42.

Evolution of civil aeromedical helicopter aviation.

Meier DR, Samper ER.

South Med J. 1989 Jul;82(7):885-91.

PMID:
2665130
43.

Colonic endometriosis: its clinical spectrum.

Samper ER, Slagle GW, Hand AM.

South Med J. 1984 Jul;77(7):912-4.

PMID:
6610941

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