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Items: 1 to 50 of 104

1.

Variables affecting penetrance of gastric and duodenal phenotype in familial adenomatous polyposis patients.

Sample DC, Samadder NJ, Pappas LM, Boucher KM, Samowitz WS, Berry T, Westover M, Nathan D, Kanth P, Byrne KR, Burt RW, Neklason DW.

BMC Gastroenterol. 2018 Jul 16;18(1):115. doi: 10.1186/s12876-018-0841-8.

2.

The TGFβ-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs.

Pellatt AJ, Mullany LE, Herrick JS, Sakoda LC, Wolff RK, Samowitz WS, Slattery ML.

J Transl Med. 2018 Jul 9;16(1):191. doi: 10.1186/s12967-018-1566-8.

3.

The p53-signaling pathway and colorectal cancer: Interactions between downstream p53 target genes and miRNAs.

Slattery ML, Mullany LE, Wolff RK, Sakoda LC, Samowitz WS, Herrick JS.

Genomics. 2018 Jun 1. pii: S0888-7543(18)30036-3. doi: 10.1016/j.ygeno.2018.05.006. [Epub ahead of print]

4.

The MAPK-Signaling Pathway in Colorectal Cancer: Dysregulated Genes and Their Association With MicroRNAs.

Slattery ML, Mullany LE, Sakoda LC, Wolff RK, Samowitz WS, Herrick JS.

Cancer Inform. 2018 Mar 26;17:1176935118766522. doi: 10.1177/1176935118766522. eCollection 2018.

5.

Active BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile.

Dehghanizadeh S, Khoddami V, Mosbruger TL, Hammoud SS, Edes K, Berry TS, Done M, Samowitz WS, DiSario JA, Luba DG, Burt RW, Jones DA.

PLoS One. 2018 Mar 28;13(3):e0192499. doi: 10.1371/journal.pone.0192499. eCollection 2018.

6.

Mutation analysis of adenomas and carcinomas of the colon: Early and late drivers.

Wolff RK, Hoffman MD, Wolff EC, Herrick JS, Sakoda LC, Samowitz WS, Slattery ML.

Genes Chromosomes Cancer. 2018 Jul;57(7):366-376. doi: 10.1002/gcc.22539. Epub 2018 Apr 30.

7.

Dysregulated genes and miRNAs in the apoptosis pathway in colorectal cancer patients.

Slattery ML, Mullany LE, Sakoda LC, Wolff RK, Samowitz WS, Herrick JS.

Apoptosis. 2018 Apr;23(3-4):237-250. doi: 10.1007/s10495-018-1451-1.

8.

Expression of Wnt-signaling pathway genes and their associations with miRNAs in colorectal cancer.

Slattery ML, Mullany LE, Sakoda LC, Samowitz WS, Wolff RK, Stevens JR, Herrick JS.

Oncotarget. 2017 Dec 23;9(5):6075-6085. doi: 10.18632/oncotarget.23636. eCollection 2018 Jan 19.

9.

Infrequently expressed miRNAs in colorectal cancer tissue and tumor molecular phenotype.

Slattery ML, Lee FY, Pellatt AJ, Mullany LE, Stevens JR, Samowitz WS, Wolff RK, Herrick JS.

Mod Pathol. 2018 Jan;31(1):209. doi: 10.1038/modpathol.2017.118.

10.

The NF-κB signalling pathway in colorectal cancer: associations between dysregulated gene and miRNA expression.

Slattery ML, Mullany LE, Sakoda L, Samowitz WS, Wolff RK, Stevens JR, Herrick JS.

J Cancer Res Clin Oncol. 2018 Feb;144(2):269-283. doi: 10.1007/s00432-017-2548-6. Epub 2017 Nov 29.

11.

Infrequently expressed miRNAs influence survival after diagnosis with colorectal cancer.

Slattery ML, Pellatt AJ, Lee FY, Herrick JS, Samowitz WS, Stevens JR, Wolff RK, Mullany LE.

Oncotarget. 2017 Aug 3;8(48):83845-83859. doi: 10.18632/oncotarget.19863. eCollection 2017 Oct 13.

12.

Chemoprevention with Cyclooxygenase and Epidermal Growth Factor Receptor Inhibitors in Familial Adenomatous Polyposis Patients: mRNA Signatures of Duodenal Neoplasia.

Delker DA, Wood AC, Snow AK, Samadder NJ, Samowitz WS, Affolter KE, Boucher KM, Pappas LM, Stijleman IJ, Kanth P, Byrne KR, Burt RW, Bernard PS, Neklason DW.

Cancer Prev Res (Phila). 2018 Jan;11(1):4-15. doi: 10.1158/1940-6207.CAPR-17-0130. Epub 2017 Nov 6.

13.

The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer.

Slattery ML, Mullany LE, Sakoda LC, Wolff RK, Stevens JR, Samowitz WS, Herrick JS.

Mol Carcinog. 2018 Feb;57(2):243-261. doi: 10.1002/mc.22752. Epub 2017 Nov 19.

14.

The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer.

Slattery ML, Herrick JS, Mullany LE, Samowitz WS, Sevens JR, Sakoda L, Wolff RK.

Genes Chromosomes Cancer. 2017 Nov;56(11):769-787. doi: 10.1002/gcc.22481. Epub 2017 Jul 30.

15.

Colorectal cancer molecular profiling: from IHC to NGS in search of optimal algorithm.

Furtado LV, Samowitz WS.

Virchows Arch. 2017 Aug;471(2):235-242. doi: 10.1007/s00428-017-2153-8. Epub 2017 May 27. Review.

PMID:
28551725
16.

Infrequently expressed miRNAs in colorectal cancer tissue and tumor molecular phenotype.

Slattery ML, Lee FY, Pellatt AJ, Mullany LE, Stevens JR, Samowitz WS, Wolff RK, Herrick JS.

Mod Pathol. 2017 Aug;30(8):1152-1169. doi: 10.1038/modpathol.2017.38. Epub 2017 May 26. Erratum in: Mod Pathol. 2018 Jan;31(1):209.

17.

A Clinicopathologic Evaluation of Incidental Fundic Gland Polyps With Dysplasia: Implications for Clinical Management.

Lloyd IE, Kohlmann WK, Gligorich K, Hall A, Lyon E, Downs-Kelly E, Samowitz WS, Bronner MP.

Am J Gastroenterol. 2017 Jul;112(7):1094-1102. doi: 10.1038/ajg.2017.125. Epub 2017 May 2.

PMID:
28462913
18.

Feasibility of Large-Scale Identification of Sessile Serrated Polyp Patients Using Electronic Records: A Utah Study.

Affolter K, Gligorich K, Samadder NJ, Samowitz WS, Curtin K.

Dig Dis Sci. 2017 Jun;62(6):1455-1463. doi: 10.1007/s10620-017-4543-9. Epub 2017 Mar 17.

PMID:
28315031
19.

Diagnostic Challenges Caused by Endoscopic Biopsy of Colonic Polyps: A Systematic Evaluation of Epithelial Misplacement With Review of Problematic Polyps From the Bowel Cancer Screening Program, United Kingdom.

Panarelli NC, Somarathna T, Samowitz WS, Kornacki S, Sanders SA, Novelli MR, Shepherd NA, Yantiss RK.

Am J Surg Pathol. 2016 Aug;40(8):1075-83. doi: 10.1097/PAS.0000000000000641.

PMID:
26975041
20.

MicroRNA profiles in colorectal carcinomas, adenomas and normal colonic mucosa: variations in miRNA expression and disease progression.

Slattery ML, Herrick JS, Pellatt DF, Stevens JR, Mullany LE, Wolff E, Hoffman MD, Samowitz WS, Wolff RK.

Carcinogenesis. 2016 Mar;37(3):245-261. doi: 10.1093/carcin/bgv249. Epub 2016 Jan 6.

21.

Sporadic microsatellite instability-high colon cancers rarely display immunohistochemical evidence of Wnt signaling activation.

Panarelli NC, Vaughn CP, Samowitz WS, Yantiss RK.

Am J Surg Pathol. 2015 Mar;39(3):313-7. doi: 10.1097/PAS.0000000000000380.

PMID:
25602793
22.

Evaluation of colorectal cancers for Lynch syndrome: practical molecular diagnostics for surgical pathologists.

Samowitz WS.

Mod Pathol. 2015 Jan;28 Suppl 1:S109-13. doi: 10.1038/modpathol.2014.127. Review.

23.

Template for reporting results of biomarker testing of specimens from patients with carcinoma of the colon and rectum.

Bartley AN, Hamilton SR, Alsabeh R, Ambinder EP, Berman M, Collins E, Fitzgibbons PL, Gress DM, Nowak JA, Samowitz WS, Zafar SY; Members of the Cancer Biomarker Reporting Workgroup, College of American Pathologists.

Arch Pathol Lab Med. 2014 Feb;138(2):166-70. doi: 10.5858/arpa.2013-0231-CP. Epub 2013 Jun 28. No abstract available.

PMID:
23808403
24.

Molecular Pathology of Gastrointestinal Cancer.

Yantiss RK, Samowitz WS.

Surg Pathol Clin. 2012 Dec;5(4):821-42. doi: 10.1016/j.path.2012.08.002. Epub 2012 Sep 30.

PMID:
26838505
25.

The frequency of previously undetectable deletions involving 3' Exons of the PMS2 gene.

Vaughn CP, Baker CL, Samowitz WS, Swensen JJ.

Genes Chromosomes Cancer. 2013 Jan;52(1):107-12. doi: 10.1002/gcc.22011. Epub 2012 Sep 25.

PMID:
23012243
26.

Septin 9 methylated DNA is a sensitive and specific blood test for colorectal cancer.

Warren JD, Xiong W, Bunker AM, Vaughn CP, Furtado LV, Roberts WL, Fang JC, Samowitz WS, Heichman KA.

BMC Med. 2011 Dec 14;9:133. doi: 10.1186/1741-7015-9-133.

27.

A PIK3CA pyrosequencing-based assay that excludes pseudogene interference.

Baker CL, Vaughn CP, Samowitz WS.

J Mol Diagn. 2012 Jan;14(1):56-60. doi: 10.1016/j.jmoldx.2011.08.004. Epub 2011 Oct 24.

PMID:
22026957
28.

Epidermal growth factor receptor pathway mutations and colorectal cancer therapy.

Grossmann AH, Samowitz WS.

Arch Pathol Lab Med. 2011 Oct;135(10):1278-82. doi: 10.5858/arpa.2011-0047-RA. Review.

PMID:
21970483
29.

Microsatellite instability and colorectal cancer.

Geiersbach KB, Samowitz WS.

Arch Pathol Lab Med. 2011 Oct;135(10):1269-77. doi: 10.5858/arpa.2011-0035-RA. Review.

PMID:
21970482
30.

Lynch syndrome screening implementation: business analysis by a healthcare system.

Gudgeon JM, Williams JL, Burt RW, Samowitz WS, Snow GL, Williams MS.

Am J Manag Care. 2011 Aug 1;17(8):e288-300.

31.

Avoidance of pseudogene interference in the detection of 3' deletions in PMS2.

Vaughn CP, Hart KJ, Samowitz WS, Swensen JJ.

Hum Mutat. 2011 Sep;32(9):1063-71. doi: 10.1002/humu.21540.

PMID:
21618646
32.

CpG island methylation in colorectal cancer: past, present and future.

Curtin K, Slattery ML, Samowitz WS.

Patholog Res Int. 2011 Apr 12;2011:902674. doi: 10.4061/2011/902674.

33.

Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations.

Curtin K, Ulrich CM, Samowitz WS, Wolff RK, Duggan DJ, Makar KW, Caan BJ, Slattery ML.

Int J Mol Epidemiol Genet. 2011 Jan 1;2(1):1-8. Epub 2010 Nov 5.

34.

Nutrients in folate-mediated, one-carbon metabolism and the risk of rectal tumors in men and women.

Curtin K, Samowitz WS, Ulrich CM, Wolff RK, Herrick JS, Caan BJ, Slattery ML.

Nutr Cancer. 2011;63(3):357-66. doi: 10.1080/01635581.2011.535965.

35.

Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.

Vaughn CP, Zobell SD, Furtado LV, Baker CL, Samowitz WS.

Genes Chromosomes Cancer. 2011 May;50(5):307-12. doi: 10.1002/gcc.20854. Epub 2011 Feb 8.

PMID:
21305640
36.

Constitutional mismatch repair-deficiency syndrome presenting as colonic adenomatous polyposis: clues from the skin.

Jasperson KW, Samowitz WS, Burt RW.

Clin Genet. 2011 Oct;80(4):394-7. doi: 10.1111/j.1399-0004.2010.01543.x. Epub 2010 Oct 6.

PMID:
21039432
37.

Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival.

Slattery ML, Curtin K, Poole EM, Duggan DJ, Samowitz WS, Peters U, Caan BJ, Potter JD, Ulrich CM.

Int J Cancer. 2011 Jun 1;128(11):2726-34. doi: 10.1002/ijc.25721. Epub 2010 Nov 28.

38.

Colorectal adenomas and cancer link to chromosome 13q22.1-13q31.3 in a large family with excess colorectal cancer.

Neklason DW, Tuohy TM, Stevens J, Otterud B, Baird L, Kerber RA, Samowitz WS, Kuwada SK, Leppert MF, Burt RW.

J Med Genet. 2010 Oct;47(10):692-9. doi: 10.1136/jmg.2009.076091. Epub 2010 Jun 3.

39.

Clinical analysis of PMS2: mutation detection and avoidance of pseudogenes.

Vaughn CP, Robles J, Swensen JJ, Miller CE, Lyon E, Mao R, Bayrak-Toydemir P, Samowitz WS.

Hum Mutat. 2010 May;31(5):588-93. doi: 10.1002/humu.21230.

PMID:
20205264
40.

Assessing tumor mutations to gain insight into base excision repair sequence polymorphisms and smoking in colon cancer.

Curtin K, Samowitz WS, Wolff RK, Ulrich CM, Caan BJ, Potter JD, Slattery ML.

Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3384-8. doi: 10.1158/1055-9965.EPI-09-0955.

41.

Quantitative evaluation of CpG island methylation in hyperplastic polyps.

Vaughn CP, Wilson AR, Samowitz WS.

Mod Pathol. 2010 Jan;23(1):151-6. doi: 10.1038/modpathol.2009.150. Epub 2009 Oct 23.

42.

Microsatellite instability and survival in rectal cancer.

Samowitz WS, Curtin K, Wolff RK, Tripp SR, Caan BJ, Slattery ML.

Cancer Causes Control. 2009 Nov;20(9):1763-8. doi: 10.1007/s10552-009-9410-3. Epub 2009 Aug 11.

43.

MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer.

Curtin K, Samowitz WS, Wolff RK, Caan BJ, Ulrich CM, Potter JD, Slattery ML.

Mol Carcinog. 2009 Nov;48(11):989-94. doi: 10.1002/mc.20566.

44.

Somatic alterations, metabolizing genes and smoking in rectal cancer.

Curtin K, Samowitz WS, Wolff RK, Herrick J, Caan BJ, Slattery ML.

Int J Cancer. 2009 Jul 1;125(1):158-64. doi: 10.1002/ijc.24338.

45.

Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.

Slattery ML, Wolff RK, Curtin K, Fitzpatrick F, Herrick J, Potter JD, Caan BJ, Samowitz WS.

Mutat Res. 2009 Jan 15;660(1-2):12-21. doi: 10.1016/j.mrfmmm.2008.10.001. Epub 2008 Oct 15.

46.

Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors.

Sweeney C, Boucher KM, Samowitz WS, Wolff RK, Albertsen H, Curtin K, Caan BJ, Slattery ML.

Genes Chromosomes Cancer. 2009 Jan;48(1):1-9. doi: 10.1002/gcc.20614.

47.

Colonic adenoma risk in familial colorectal cancer--a study of six extended kindreds.

Neklason DW, Thorpe BL, Ferrandez A, Tumbapura A, Boucher K, Garibotti G, Kerber RA, Solomon CH, Samowitz WS, Fang JC, Mineau GP, Leppert MF, Burt RW, Kuwada SK.

Am J Gastroenterol. 2008 Oct;103(10):2577-84. doi: 10.1111/j.1572-0241.2008.02019.x. Epub 2008 Jul 30.

48.

DNA methylation in breast and colorectal cancers.

Samowitz WS, Ogino S.

Mod Pathol. 2008 Aug;21(8):1054; author reply 1054-5. doi: 10.1038/modpathol.2008.18. No abstract available.

49.

The MLH1 -93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancer.

Samowitz WS, Curtin K, Wolff RK, Albertsen H, Sweeney C, Caan BJ, Ulrich CM, Potter JD, Slattery ML.

Genes Chromosomes Cancer. 2008 Oct;47(10):835-44. doi: 10.1002/gcc.20584.

50.

Confirmation of single exon deletions in MLH1 and MSH2 using quantitative polymerase chain reaction.

Vaughn CP, Lyon E, Samowitz WS.

J Mol Diagn. 2008 Jul;10(4):355-60. doi: 10.2353/jmoldx.2008.080021. Epub 2008 Jun 13.

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