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Items: 11


Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib).

Germann UA, Furey BF, Markland W, Hoover RR, Aronov AM, Roix JJ, Hale M, Boucher DM, Sorrell DA, Martinez-Botella G, Fitzgibbon M, Shapiro P, Wick MJ, Samadani R, Meshaw K, Groover A, DeCrescenzo G, Namchuk M, Emery CM, Saha S, Welsch DJ.

Mol Cancer Ther. 2017 Nov;16(11):2351-2363. doi: 10.1158/1535-7163.MCT-17-0456. Epub 2017 Sep 22.


Novel Noncatalytic Substrate-Selective p38α-Specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-Inflammatory Activity.

Shah NG, Tulapurkar ME, Ramarathnam A, Brophy A, Martinez R 3rd, Hom K, Hodges T, Samadani R, Singh IS, MacKerell AD Jr, Shapiro P, Hasday JD.

J Immunol. 2017 Apr 15;198(8):3296-3306. doi: 10.4049/jimmunol.1602059. Epub 2017 Mar 15.


Small-molecule inhibitors of ERK-mediated immediate early gene expression and proliferation of melanoma cells expressing mutated BRaf.

Samadani R, Zhang J, Brophy A, Oashi T, Priyakumar UD, Raman EP, St John FJ, Jung KY, Fletcher S, Pozharski E, MacKerell AD Jr, Shapiro P.

Biochem J. 2015 May 1;467(3):425-38. doi: 10.1042/BJ20131571.


Exosomal Proteome Profiling: A Potential Multi-Marker Cellular Phenotyping Tool to Characterize Hypoxia-Induced Radiation Resistance in Breast Cancer.

Thomas SN, Liao Z, Clark D, Chen Y, Samadani R, Mao L, Ann DK, Baulch JE, Shapiro P, Yang AJ.

Proteomes. 2013 Sep 1;1(2):87-108.


Stereo matching and view interpolation based on image domain triangulation.

Fickel GP, Jung CR, Malzbender T, Samadani R, Culbertson B.

IEEE Trans Image Process. 2013 Sep;22(9):3353-65. doi: 10.1109/TIP.2013.2264819. Epub 2013 May 23.


Structural modifications of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione that improve selectivity for inhibiting the proliferation of melanoma cells containing active ERK signaling.

Jung KY, Samadani R, Chauhan J, Nevels K, Yap JL, Zhang J, Worlikar S, Lanning ME, Chen L, Ensey M, Shukla S, Salmo R, Heinzl G, Gordon C, Dukes T, MacKerell AD Jr, Shapiro P, Fletcher S.

Org Biomol Chem. 2013 Jun 14;11(22):3706-32. doi: 10.1039/c3ob40199e.


Importance of domain closure for the autoactivation of ERK2.

Barr D, Oashi T, Burkhard K, Lucius S, Samadani R, Zhang J, Shapiro P, MacKerell AD, van der Vaart A.

Biochemistry. 2011 Sep 20;50(37):8038-48. doi: 10.1021/bi200503a. Epub 2011 Aug 25.


No-reference blur assessment of digital pictures based on multifeature classifiers.

Ciancio A, da Costa AL, da Silva EA, Said A, Samadani R, Obrador P.

IEEE Trans Image Process. 2011 Jan;20(1):64-75. doi: 10.1109/TIP.2010.2053549.


Image thumbnails that represent blur and noise.

Samadani R, Mauer TA, Berfanger DM, Clark JH.

IEEE Trans Image Process. 2010 Feb;19(2):363-73. doi: 10.1109/TIP.2009.2035847. Epub 2009 Nov 3.


Distributed image coding for digital image recovery from the print-scan channel.

Samadani R, Mukherjee D.

IEEE Trans Image Process. 2010 Mar;19(3):702-11. doi: 10.1109/TIP.2009.2035887. Epub 2009 Nov 3.


A finite mixtures algorithm for finding proportions in SAR images.

Samadani R.

IEEE Trans Image Process. 1995;4(8):1182-6.


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