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Items: 15


Nav1.5 in astrocytes plays a sex-specific role in clinical outcomes in a mouse model of multiple sclerosis.

Pappalardo LW, Samad OA, Liu S, Zwinger PJ, Black JA, Waxman SG.

Glia. 2018 Oct;66(10):2174-2187. doi: 10.1002/glia.23470. Epub 2018 Sep 8.


Virus-Mediated Knockdown of Nav1.3 in Dorsal Root Ganglia of STZ-Induced Diabetic Rats Alleviates Tactile Allodynia.

Tan AM, Samad OA, Dib-Hajj SD, Waxman SG.

Mol Med. 2015 Jun 18;21:544-52. doi: 10.2119/molmed.2015.00063.


Voltage-gated sodium channel Nav 1.5 contributes to astrogliosis in an in vitro model of glial injury via reverse Na+ /Ca2+ exchange.

Pappalardo LW, Samad OA, Black JA, Waxman SG.

Glia. 2014 Jul;62(7):1162-75. doi: 10.1002/glia.22671. Epub 2014 Apr 17.


Genetic control of the segregation of pain-related sensory neurons innervating the cutaneous versus deep tissues.

Yang FC, Tan T, Huang T, Christianson J, Samad OA, Liu Y, Roberson D, Davis BM, Ma Q.

Cell Rep. 2013 Dec 12;5(5):1353-64. doi: 10.1016/j.celrep.2013.11.005. Epub 2013 Dec 5.


Burn injury-induced mechanical allodynia is maintained by Rac1-regulated dendritic spine dysgenesis.

Tan AM, Samad OA, Liu S, Bandaru S, Zhao P, Waxman SG.

Exp Neurol. 2013 Oct;248:509-19. doi: 10.1016/j.expneurol.2013.07.017. Epub 2013 Aug 8.


Virus-mediated shRNA knockdown of Na(v)1.3 in rat dorsal root ganglion attenuates nerve injury-induced neuropathic pain.

Samad OA, Tan AM, Cheng X, Foster E, Dib-Hajj SD, Waxman SG.

Mol Ther. 2013 Jan;21(1):49-56. doi: 10.1038/mt.2012.169. Epub 2012 Aug 21.


Maladaptive dendritic spine remodeling contributes to diabetic neuropathic pain.

Tan AM, Samad OA, Fischer TZ, Zhao P, Persson AK, Waxman SG.

J Neurosci. 2012 May 16;32(20):6795-807. doi: 10.1523/JNEUROSCI.1017-12.2012.


Phenotypic switching of nonpeptidergic cutaneous sensory neurons following peripheral nerve injury.

Wang T, Molliver DC, Jing X, Schwartz ES, Yang FC, Samad OA, Ma Q, Davis BM.

PLoS One. 2011;6(12):e28908. doi: 10.1371/journal.pone.0028908. Epub 2011 Dec 21.


The BMP coreceptor RGMb promotes while the endogenous BMP antagonist noggin reduces neurite outgrowth and peripheral nerve regeneration by modulating BMP signaling.

Ma CH, Brenner GJ, Omura T, Samad OA, Costigan M, Inquimbert P, Niederkofler V, Salie R, Sun CC, Lin HY, Arber S, Coppola G, Woolf CJ, Samad TA.

J Neurosci. 2011 Dec 14;31(50):18391-400. doi: 10.1523/JNEUROSCI.4550-11.2011.


JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain.

Gao YJ, Zhang L, Samad OA, Suter MR, Yasuhiko K, Xu ZZ, Park JY, Lind AL, Ma Q, Ji RR.

J Neurosci. 2009 Apr 1;29(13):4096-108. doi: 10.1523/JNEUROSCI.3623-08.2009.


An ultraconserved Hox-Pbx responsive element resides in the coding sequence of Hoxa2 and is active in rhombomere 4.

Lampe X, Samad OA, Guiguen A, Matis C, Remacle S, Picard JJ, Rijli FM, Rezsohazy R.

Nucleic Acids Res. 2008 Jun;36(10):3214-25. doi: 10.1093/nar/gkn148. Epub 2008 Apr 16.


Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.

Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q.

Neuron. 2006 Feb 2;49(3):365-77.


Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes.

Cheng L, Samad OA, Xu Y, Mizuguchi R, Luo P, Shirasawa S, Goulding M, Ma Q.

Nat Neurosci. 2005 Nov;8(11):1510-5. Epub 2005 Oct 23. Erratum in: Nat Neurosci. 2005 Dec;8(12):1791.


Integration of anteroposterior and dorsoventral regulation of Phox2b transcription in cranial motoneuron progenitors by homeodomain proteins.

Samad OA, Geisen MJ, Caronia G, Varlet I, Zappavigna V, Ericson J, Goridis C, Rijli FM.

Development. 2004 Aug;131(16):4071-83.


Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of CNS progenitors.

Pattyn A, Vallstedt A, Dias JM, Samad OA, Krumlauf R, Rijli FM, Brunet JF, Ericson J.

Genes Dev. 2003 Mar 15;17(6):729-37.

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