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Items: 1 to 50 of 186

1.

Microbiome Signatures Associated with Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease.

Schwimmer JB, Johnson JS, Angeles JE, Behling C, Belt PH, Borecki I, Bross C, Durelle J, Goyal NP, Hamilton G, Holtz ML, Lavine JE, Mitreva M, Newton KP, Pan A, Simpson PM, Sirlin CB, Sodergren E, Tyagi R, Yates KP, Weinstock G, Salzman NH.

Gastroenterology. 2019 Jun 27. pii: S0016-5085(19)41037-8. doi: 10.1053/j.gastro.2019.06.028. [Epub ahead of print]

PMID:
31255652
2.

Challenges in IBD Research: Preclinical Human IBD Mechanisms.

Pizarro TT, Stappenbeck TS, Rieder F, Rosen MJ, Colombel JF, Donowitz M, Towne J, Mazmanian SK, Faith JJ, Hodin RA, Garrett WS, Fichera A, Poritz LS, Cortes CJ, Shtraizent N, Honig G, Snapper SB, Hurtado-Lorenzo A, Salzman NH, Chang EB.

Inflamm Bowel Dis. 2019 May 16;25(Supplement_2):S5-S12. doi: 10.1093/ibd/izz075.

PMID:
31095706
3.

Fecal Microbial Transplant Capsules Are Safe in Hepatic Encephalopathy: A Phase 1, Randomized, Placebo-Controlled Trial.

Bajaj JS, Salzman NH, Acharya C, Sterling RK, White MB, Gavis EA, Fagan A, Hayward M, Holtz ML, Matherly S, Lee H, Osman M, Siddiqui MS, Fuchs M, Puri P, Sikaroodi M, Gillevet PM.

Hepatology. 2019 Apr 30. doi: 10.1002/hep.30690. [Epub ahead of print]

PMID:
31038755
4.

Longitudinal changes in the gut microbiome of infants on total parenteral nutrition.

Dahlgren AF, Pan A, Lam V, Gouthro KC, Simpson PM, Salzman NH, Nghiem-Rao TH.

Pediatr Res. 2019 Jul;86(1):107-114. doi: 10.1038/s41390-019-0391-y. Epub 2019 Apr 9.

PMID:
30965357
5.

Quantifying step length using two-dimensional video in individuals with Parkinson's disease.

Stricker M, Hinde D, Rolland A, Salzman N, Watson A, Almonroeder TG.

Physiother Theory Pract. 2019 Mar 21:1-4. doi: 10.1080/09593985.2019.1594472. [Epub ahead of print]

PMID:
30896266
6.

Sortase-Dependent Proteins Promote Gastrointestinal Colonization by Enterococci.

Banla LI, Pickrum AM, Hayward M, Kristich CJ, Salzman NH.

Infect Immun. 2019 Apr 23;87(5). pii: e00853-18. doi: 10.1128/IAI.00853-18. Print 2019 Mar.

PMID:
30804098
7.

Colonization of the mammalian intestinal tract by enterococci.

Banla LI, Salzman NH, Kristich CJ.

Curr Opin Microbiol. 2019 Feb;47:26-31. doi: 10.1016/j.mib.2018.10.005. Epub 2018 Nov 13. Review.

PMID:
30439685
8.

Engineered E. coli Nissle 1917 for the reduction of vancomycin-resistant Enterococcus in the intestinal tract.

Geldart KG, Kommineni S, Forbes M, Hayward M, Dunny GM, Salzman NH, Kaznessis YN.

Bioeng Transl Med. 2018 Sep 8;3(3):197-208. doi: 10.1002/btm2.10107. eCollection 2018 Sep.

9.

Lactobacillus plantarum 299v Supplementation Improves Vascular Endothelial Function and Reduces Inflammatory Biomarkers in Men With Stable Coronary Artery Disease.

Malik M, Suboc TM, Tyagi S, Salzman N, Wang J, Ying R, Tanner MJ, Kakarla M, Baker JE, Widlansky ME.

Circ Res. 2018 Oct 12;123(9):1091-1102. doi: 10.1161/CIRCRESAHA.118.313565.

PMID:
30355158
10.

Ceftriaxone Administration Disrupts Intestinal Homeostasis, Mediating Noninflammatory Proliferation and Dissemination of Commensal Enterococci.

Chakraborty R, Lam V, Kommineni S, Stromich J, Hayward M, Kristich CJ, Salzman NH.

Infect Immun. 2018 Nov 20;86(12). pii: e00674-18. doi: 10.1128/IAI.00674-18. Print 2018 Dec.

11.

Intestinal Microbiota Disruption Reduces Regulatory T Cells and Increases Respiratory Viral Infection Mortality Through Increased IFNγ Production.

Grayson MH, Camarda LE, Hussain SA, Zemple SJ, Hayward M, Lam V, Hunter DA, Santoro JL, Rohlfing M, Cheung DS, Salzman NH.

Front Immunol. 2018 Jul 10;9:1587. doi: 10.3389/fimmu.2018.01587. eCollection 2018.

12.

Exploring bioactive peptides from bacterial secretomes using PepSAVI-MS: identification and characterization of Bac-21 from Enterococcus faecalis pPD1.

Kirkpatrick CL, Parsley NC, Bartges TE, Wing CE, Kommineni S, Kristich CJ, Salzman NH, Patrie SM, Hicks LM.

Microb Biotechnol. 2018 Sep;11(5):943-951. doi: 10.1111/1751-7915.13299. Epub 2018 Jul 16.

13.

A model of TH17-associated ileal hyperplasia that requires both IL-17A and IFNγ to generate self-tolerance and prevent colitis.

Jeschke JC, Mayne CG, Ziegelbauer J, DeCiantis CL, Singh S, Kumar SN, Suchi M, Iwakura Y, Drobyski WR, Salzman NH, Williams CB.

Mucosal Immunol. 2018 Jul;11(4):1127-1137. doi: 10.1038/s41385-018-0023-6. Epub 2018 May 4.

14.

A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells.

Chang YL, Rossetti M, Vlamakis H, Casero D, Sunga G, Harre N, Miller S, Humphries R, Stappenbeck T, Simpson KW, Sartor RB, Wu G, Lewis J, Bushman F, McGovern DPB, Salzman N, Borneman J, Xavier R, Huttenhower C, Braun J.

Mucosal Immunol. 2019 Mar;12(2):457-467. doi: 10.1038/s41385-018-0022-7. Epub 2018 Apr 25.

15.

Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility.

Henschel AM, Cabrera SM, Kaldunski ML, Jia S, Geoffrey R, Roethle MF, Lam V, Chen YG, Wang X, Salzman NH, Hessner MJ.

PLoS One. 2018 Jan 2;13(1):e0190351. doi: 10.1371/journal.pone.0190351. eCollection 2018.

16.

Modulators of Enterococcus faecalis Cell Envelope Integrity and Antimicrobial Resistance Influence Stable Colonization of the Mammalian Gastrointestinal Tract.

Banla IL, Kommineni S, Hayward M, Rodrigues M, Palmer KL, Salzman NH, Kristich CJ.

Infect Immun. 2017 Dec 19;86(1). pii: e00381-17. doi: 10.1128/IAI.00381-17. Print 2018 Jan.

17.

Intestinal alkaline phosphatase deficiency leads to dysbiosis and bacterial translocation in the newborn intestine.

Fawley J, Koehler S, Cabrera S, Lam V, Fredrich K, Hessner M, Salzman N, Gourlay D.

J Surg Res. 2017 Oct;218:35-42. doi: 10.1016/j.jss.2017.03.049. Epub 2017 Apr 13.

PMID:
28985873
18.

Continued Alcohol Misuse in Human Cirrhosis is Associated with an Impaired Gut-Liver Axis.

Bajaj JS, Kakiyama G, Zhao D, Takei H, Fagan A, Hylemon P, Zhou H, Pandak WM, Nittono H, Fiehn O, Salzman N, Holtz M, Simpson P, Gavis EA, Heuman DM, Liu R, Kang DJ, Sikaroodi M, Gillevet PM.

Alcohol Clin Exp Res. 2017 Nov;41(11):1857-1865. doi: 10.1111/acer.13498. Epub 2017 Oct 11.

PMID:
28925102
19.

Black Raspberries and Their Anthocyanin and Fiber Fractions Alter the Composition and Diversity of Gut Microbiota in F-344 Rats.

Pan P, Lam V, Salzman N, Huang YW, Yu J, Zhang J, Wang LS.

Nutr Cancer. 2017 Aug-Sep;69(6):943-951. doi: 10.1080/01635581.2017.1340491. Epub 2017 Jul 18.

20.

Harnessing bacteriocin biology as targeted therapy in the GI tract.

Kommineni S, Kristich CJ, Salzman NH.

Gut Microbes. 2016 Nov;7(6):512-517. Epub 2016 Sep 13.

21.

Paneth cell defects in Crohn's disease patients promote dysbiosis.

Liu TC, Gurram B, Baldridge MT, Head R, Lam V, Luo C, Cao Y, Simpson P, Hayward M, Holtz ML, Bousounis P, Noe J, Lerner D, Cabrera J, Biank V, Stephens M, Huttenhower C, McGovern DP, Xavier RJ, Stappenbeck TS, Salzman NH.

JCI Insight. 2016 Jun 2;1(8):e86907. doi: 10.1172/jci.insight.86907.

22.

Intestinal Microbial Metabolites Are Linked to Severity of Myocardial Infarction in Rats.

Lam V, Su J, Hsu A, Gross GJ, Salzman NH, Baker JE.

PLoS One. 2016 Aug 9;11(8):e0160840. doi: 10.1371/journal.pone.0160840. eCollection 2016.

23.

Alternatively Activated Macrophages Boost Induced Regulatory T and Th17 Cell Responses during Immunotherapy for Colitis.

Haribhai D, Ziegelbauer J, Jia S, Upchurch K, Yan K, Schmitt EG, Salzman NH, Simpson P, Hessner MJ, Chatila TA, Williams CB.

J Immunol. 2016 Apr 15;196(8):3305-17. doi: 10.4049/jimmunol.1501956. Epub 2016 Feb 29.

24.

Intact Regulatory T-Cell Function but Defective Generation of IL-17A-Producing CD4+ T Cells in XIAP Deficiency.

Gurram B, Hammelev E, Syverson G, Haribhai D, Yan K, Simpson P, Salzman N, Verbsky JW.

J Pediatr Gastroenterol Nutr. 2016 Aug;63(2):218-25. doi: 10.1097/MPG.0000000000001122.

PMID:
26825770
25.

Plasma-induced signatures reveal an extracellular milieu possessing an immunoregulatory bias in treatment-naive paediatric inflammatory bowel disease.

Gurram B, Salzman NH, Kaldunski ML, Jia S, Li BU, Stephens M, Sood MR, Hessner MJ.

Clin Exp Immunol. 2016 Apr;184(1):36-49. doi: 10.1111/cei.12753. Epub 2016 Jan 29.

26.

Bacteriocin production augments niche competition by enterococci in the mammalian gastrointestinal tract.

Kommineni S, Bretl DJ, Lam V, Chakraborty R, Hayward M, Simpson P, Cao Y, Bousounis P, Kristich CJ, Salzman NH.

Nature. 2015 Oct 29;526(7575):719-22. doi: 10.1038/nature15524. Epub 2015 Oct 19.

27.

Gut Microbial Dysbiosis Due to Helicobacter Drives an Increase in Marginal Zone B Cells in the Absence of IL-10 Signaling in Macrophages.

Ray A, Basu S, Gharaibeh RZ, Cook LC, Kumar R, Lefkowitz EJ, Walker CR, Morrow CD, Franklin CL, Geiger TL, Salzman NH, Fodor A, Dittel BN.

J Immunol. 2015 Oct 1;195(7):3071-85. doi: 10.4049/jimmunol.1500153. Epub 2015 Aug 31.

28.

Increased susceptibility to otitis media in a Splunc1-deficient mouse model.

Bartlett JA, Meyerholz DK, Wohlford-Lenane CL, Naumann PW, Salzman NH, McCray PB Jr.

Dis Model Mech. 2015 May;8(5):501-8. doi: 10.1242/dmm.019646. Epub 2015 Mar 12.

29.

Selection of models for the analysis of risk-factor trees: leveraging biological knowledge to mine large sets of risk factors with application to microbiome data.

Zhang Q, Abel H, Wells A, Lenzini P, Gomez F, Province MA, Templeton AA, Weinstock GM, Salzman NH, Borecki IB.

Bioinformatics. 2015 May 15;31(10):1607-13. doi: 10.1093/bioinformatics/btu855. Epub 2015 Jan 6.

30.

The role of the microbiome in immune cell development.

Salzman NH.

Ann Allergy Asthma Immunol. 2014 Dec;113(6):593-8. doi: 10.1016/j.anai.2014.08.020. Review. No abstract available.

PMID:
25466801
31.

Detection of antimicrobial (poly)peptides with acid urea polyacrylamide gel electrophoresis followed by Western immunoblot.

Porter E, Valore EV, Anouseyan R, Salzman NH.

Methods Mol Biol. 2015;1225:105-15. doi: 10.1007/978-1-4939-1625-2_7.

PMID:
25253251
32.

Calprotectin in cystic fibrosis.

Rumman N, Sultan M, El-Chammas K, Goh V, Salzman N, Quintero D, Werlin S.

BMC Pediatr. 2014 May 29;14:133. doi: 10.1186/1471-2431-14-133.

33.

Conventional CD4+ T cells regulate IL-22-producing intestinal innate lymphoid cells.

Korn LL, Thomas HL, Hubbeling HG, Spencer SP, Sinha R, Simkins HM, Salzman NH, Bushman FD, Laufer TM.

Mucosal Immunol. 2014 Sep;7(5):1045-57. doi: 10.1038/mi.2013.121. Epub 2014 Jan 22.

34.

Dysbiosis--a consequence of Paneth cell dysfunction.

Salzman NH, Bevins CL.

Semin Immunol. 2013 Nov 30;25(5):334-41. doi: 10.1016/j.smim.2013.09.006. Epub 2013 Nov 14. Review.

PMID:
24239045
35.

Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression.

Schmitt EG, Haribhai D, Jeschke JC, Co DO, Ziegelbauer J, Yan K, Iwakura Y, Mishra MK, Simpson P, Salzman NH, Williams CB.

J Immunol. 2013 Dec 1;191(11):5460-76. doi: 10.4049/jimmunol.1301576. Epub 2013 Oct 25.

36.

Loss of TLR2 worsens spontaneous colitis in MDR1A deficiency through commensally induced pyroptosis.

Ey B, Eyking A, Klepak M, Salzman NH, Göthert JR, Rünzi M, Schmid KW, Gerken G, Podolsky DK, Cario E.

J Immunol. 2013 Jun 1;190(11):5676-88. doi: 10.4049/jimmunol.1201592. Epub 2013 May 1.

37.

IL-10 produced by induced regulatory T cells (iTregs) controls colitis and pathogenic ex-iTregs during immunotherapy.

Schmitt EG, Haribhai D, Williams JB, Aggarwal P, Jia S, Charbonnier LM, Yan K, Lorier R, Turner A, Ziegelbauer J, Georgiev P, Simpson P, Salzman NH, Hessner MJ, Broeckel U, Chatila TA, Williams CB.

J Immunol. 2012 Dec 15;189(12):5638-48. doi: 10.4049/jimmunol.1200936. Epub 2012 Nov 2.

38.

The β₃-integrin ligand of Borrelia burgdorferi is critical for infection of mice but not ticks.

Ristow LC, Miller HE, Padmore LJ, Chettri R, Salzman N, Caimano MJ, Rosa PA, Coburn J.

Mol Microbiol. 2012 Sep;85(6):1105-18. doi: 10.1111/j.1365-2958.2012.08160.x. Epub 2012 Jul 18.

39.

Human α-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets.

Chu H, Pazgier M, Jung G, Nuccio SP, Castillo PA, de Jong MF, Winter MG, Winter SE, Wehkamp J, Shen B, Salzman NH, Underwood MA, Tsolis RM, Young GM, Lu W, Lehrer RI, Bäumler AJ, Bevins CL.

Science. 2012 Jul 27;337(6093):477-81. doi: 10.1126/science.1218831. Epub 2012 Jun 21.

40.

MprA and DosR coregulate a Mycobacterium tuberculosis virulence operon encoding Rv1813c and Rv1812c.

Bretl DJ, He H, Demetriadou C, White MJ, Penoske RM, Salzman NH, Zahrt TC.

Infect Immun. 2012 Sep;80(9):3018-33. doi: 10.1128/IAI.00520-12. Epub 2012 Jun 11.

41.

Intestinal microbiota as novel biomarkers of prior radiation exposure.

Lam V, Moulder JE, Salzman NH, Dubinsky EA, Andersen GL, Baker JE.

Radiat Res. 2012 May;177(5):573-83. Epub 2012 Mar 23.

PMID:
22439602
42.

A novel IL-10-independent regulatory role for B cells in suppressing autoimmunity by maintenance of regulatory T cells via GITR ligand.

Ray A, Basu S, Williams CB, Salzman NH, Dittel BN.

J Immunol. 2012 Apr 1;188(7):3188-98. doi: 10.4049/jimmunol.1103354. Epub 2012 Feb 24.

43.

Alternative luminal activation mechanisms for paneth cell α-defensins.

Mastroianni JR, Costales JK, Zaksheske J, Selsted ME, Salzman NH, Ouellette AJ.

J Biol Chem. 2012 Mar 30;287(14):11205-12. doi: 10.1074/jbc.M111.333559. Epub 2012 Feb 13.

44.

Intestinal microbiota determine severity of myocardial infarction in rats.

Lam V, Su J, Koprowski S, Hsu A, Tweddell JS, Rafiee P, Gross GJ, Salzman NH, Baker JE.

FASEB J. 2012 Apr;26(4):1727-35. doi: 10.1096/fj.11-197921. Epub 2012 Jan 12.

45.

Expansion of Paneth cell population in response to enteric Salmonella enterica serovar Typhimurium infection.

Martinez Rodriguez NR, Eloi MD, Huynh A, Dominguez T, Lam AH, Carcamo-Molina D, Naser Z, Desharnais R, Salzman NH, Porter E.

Infect Immun. 2012 Jan;80(1):266-75. doi: 10.1128/IAI.05638-11. Epub 2011 Oct 17.

46.

The potter's wheel: the host's role in sculpting its microbiota.

Bevins CL, Salzman NH.

Cell Mol Life Sci. 2011 Nov;68(22):3675-85. doi: 10.1007/s00018-011-0830-3. Epub 2011 Oct 4. Review.

47.

A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity.

Haribhai D, Williams JB, Jia S, Nickerson D, Schmitt EG, Edwards B, Ziegelbauer J, Yassai M, Li SH, Relland LM, Wise PM, Chen A, Zheng YQ, Simpson PM, Gorski J, Salzman NH, Hessner MJ, Chatila TA, Williams CB.

Immunity. 2011 Jul 22;35(1):109-22. doi: 10.1016/j.immuni.2011.03.029. Epub 2011 Jun 30.

48.

Targeted intestinal epithelial deletion of the chemokine receptor CXCR4 reveals important roles for extracellular-regulated kinase-1/2 in restitution.

Zimmerman NP, Vongsa RA, Faherty SL, Salzman NH, Dwinell MB.

Lab Invest. 2011 Jul;91(7):1040-55. doi: 10.1038/labinvest.2011.77. Epub 2011 May 2.

49.

Paneth cell defensins and the regulation of the microbiome: détente at mucosal surfaces.

Salzman NH.

Gut Microbes. 2010 Nov-Dec;1(6):401-6. doi: 10.4161/gmic.1.6.14076. Review.

50.

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis.

Bevins CL, Salzman NH.

Nat Rev Microbiol. 2011 May;9(5):356-68. doi: 10.1038/nrmicro2546. Epub 2011 Mar 22. Review.

PMID:
21423246

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