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Items: 1 to 50 of 198

1.

HSP70iQ435A-Encoding DNA Repigments Vitiligo Lesions in Sinclair Swine.

Henning SW, Fernandez MF, Mahon JP, Duff R, Azarafrooz F, Guevara-Patiño JA, Rademaker AW, Salzman AL, Le Poole IC.

J Invest Dermatol. 2018 Dec;138(12):2531-2539. doi: 10.1016/j.jid.2018.06.186. Epub 2018 Jul 19. Erratum in: J Invest Dermatol. 2019 Apr;139(4):977.

PMID:
30031029
2.

CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis.

Zohar Y, Wildbaum G, Novak R, Salzman AL, Thelen M, Alon R, Barsheshet Y, Karp CL, Karin N.

J Clin Invest. 2018 Mar 1;128(3):1200-1201. doi: 10.1172/JCI120358. Epub 2018 Mar 1. No abstract available.

3.

R-100 improves pulmonary function and systemic fluid balance in sheep with combined smoke-inhalation injury and Pseudomonas aeruginosa sepsis.

Ito H, Malgerud E, Asmussen S, Lopez E, Salzman AL, Enkhbaatar P.

J Transl Med. 2017 Dec 28;15(1):266. doi: 10.1186/s12967-017-1366-6.

4.

CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis.

Zohar Y, Wildbaum G, Novak R, Salzman AL, Thelen M, Alon R, Barsheshet Y, Karp CL, Karin N.

J Clin Invest. 2017 Oct 2;127(10):3913. doi: 10.1172/JCI97015. Epub 2017 Aug 28. No abstract available.

5.

Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.

Berger NA, Besson VC, Boulares AH, Bürkle A, Chiarugi A, Clark RS, Curtin NJ, Cuzzocrea S, Dawson TM, Dawson VL, Haskó G, Liaudet L, Moroni F, Pacher P, Radermacher P, Salzman AL, Snyder SH, Soriano FG, Strosznajder RP, Sümegi B, Swanson RA, Szabo C.

Br J Pharmacol. 2018 Jan;175(2):192-222. doi: 10.1111/bph.13748. Epub 2017 Mar 26. Review.

6.

TSC2 Deficiency Unmasks a Novel Necrosis Pathway That Is Suppressed by the RIP1/RIP3/MLKL Signaling Cascade.

Filipczak PT, Thomas C, Chen W, Salzman A, McDonald JD, Lin Y, Belinsky SA.

Cancer Res. 2016 Dec 15;76(24):7130-7139. Epub 2016 Oct 18.

7.

CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis.

Zohar Y, Wildbaum G, Novak R, Salzman AL, Thelen M, Alon R, Barsheshet Y, Karp CL, Karin N.

J Clin Invest. 2014 May;124(5):2009-22. doi: 10.1172/JCI71951. Epub 2014 Apr 8. Erratum in: J Clin Invest. 2018 Mar 1;128(3):1200-1201.

8.

Locomotor requirements for bipedal locomotion: a Delphi survey.

Hedman LD, Morris DM, Graham CL, Brown CJ, Ford MP, Ingram DA, Hilliard MJ, Salzman AJ.

Phys Ther. 2014 Jan;94(1):52-67. doi: 10.2522/ptj.20120514. Epub 2013 Aug 8.

PMID:
23929828
9.

Psychomotor deficits associated with hyponatremia: a retrospective analysis.

Josiassen RC, Filmyer DM, Geboy AG, Martin DM, Curtis JL, Shaughnessy RA, Salzman A, Orlandi C.

Clin Neuropsychol. 2012;26(1):74-87. doi: 10.1080/13854046.2011.628697. Epub 2011 Nov 17.

PMID:
22087848
10.

Adrenoleukodystrophy patient perspective: turning despair into a gene therapy breakthrough.

Salzman A.

Hum Gene Ther. 2011 Jun;22(6):647-8. doi: 10.1089/hum.2011.2503. No abstract available.

PMID:
21651376
11.

The peroxynitrite catalyst WW-85 improves microcirculation in ovine smoke inhalation injury and septic shock.

Maybauer DM, Maybauer MO, Szabó C, Westphal M, Traber LD, Salzman AL, Herndon DN, Traber DL.

Burns. 2011 Aug;37(5):842-50. doi: 10.1016/j.burns.2010.12.020. Epub 2011 Feb 22.

12.

Metacognition in schizophrenia: correlates and stability of deficits in theory of mind and self-reflectivity.

Lysaker PH, Olesek KL, Warman DM, Martin JM, Salzman AK, Nicolò G, Salvatore G, Dimaggio G.

Psychiatry Res. 2011 Nov 30;190(1):18-22. doi: 10.1016/j.psychres.2010.07.016. Epub 2010 Aug 8.

PMID:
20696482
13.

The peroxynitrite catalyst WW-85 improves pulmonary function in ovine septic shock.

Maybauer DM, Maybauer MO, Szabó C, Cox RA, Westphal M, Kiss L, Horvath EM, Traber LD, Hawkins HK, Salzman AL, Southan GJ, Herndon DN, Traber DL.

Shock. 2011 Feb;35(2):148-55. doi: 10.1097/SHK.0b013e3181eb4556.

14.

The novel inosine analogue INO-2002 exerts an anti-inflammatory effect in a murine model of acute lung injury.

Mabley JG, Pacher P, Murthy KG, Williams W, Southan GJ, Salzman AL, Szabo C.

Shock. 2009 Sep;32(3):258-62. doi: 10.1097/SHK.0b013e31819c3414.

15.

Lung-protective effects of the metalloporphyrinic peroxynitrite decomposition catalyst WW-85 in interleukin-2 induced toxicity.

Maybauer DM, Maybauer MO, Szabó C, Westphal M, Traber LD, Enkhbaatar P, Murthy KG, Nakano Y, Salzman AL, Herndon DN, Traber DL.

Biochem Biophys Res Commun. 2008 Dec 19;377(3):786-91. doi: 10.1016/j.bbrc.2008.10.066. Epub 2008 Oct 23.

16.

The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.

Mabley JG, Pacher P, Murthy KG, Williams W, Southan GJ, Salzman AL, Szabo C.

J Endocrinol. 2008 Sep;198(3):581-9. doi: 10.1677/JOE-07-0511. Epub 2008 Jun 18.

17.

A randomized, placebo-controlled trial to evaluate the tolerability, safety, pharmacokinetics, and pharmacodynamics of a potent inhibitor of poly(ADP-ribose) polymerase (INO-1001) in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: results of the TIMI 37 trial.

Morrow DA, Brickman CM, Murphy SA, Baran K, Krakover R, Dauerman H, Kumar S, Slomowitz N, Grip L, McCabe CH, Salzman AL.

J Thromb Thrombolysis. 2009 May;27(4):359-64. doi: 10.1007/s11239-008-0230-1. Epub 2008 Jun 6.

PMID:
18535785
18.

Short-term effects of glipizide (an adenosine triphosphate-sensitive potassium channel inhibitor) on cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep.

Lange M, Szabo C, Van Aken H, Williams W, Traber DL, Daudel F, Bröking K, Salzman AL, Bone HG, Westphal M.

Shock. 2006 Nov;26(5):516-21.

PMID:
17047524
19.

Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft.

Cheng CL, Johnson SP, Keir ST, Quinn JA, Ali-Osman F, Szabo C, Li H, Salzman AL, Dolan ME, Modrich P, Bigner DD, Friedman HS.

Mol Cancer Ther. 2005 Sep;4(9):1364-8.

20.

Discovery of potent poly(ADP-ribose) polymerase-1 inhibitors from the modification of indeno[1,2-c]isoquinolinone.

Jagtap PG, Baloglu E, Southan GJ, Mabley JG, Li H, Zhou J, van Duzer J, Salzman AL, Szabó C.

J Med Chem. 2005 Aug 11;48(16):5100-3.

PMID:
16078828
21.

Antibodies raised against N'-terminal Pseudomonas aeruginosa flagellin prevent mortality in lethal murine models of infection.

Neville LF, Barnea Y, Hammer-Munz O, Gur E, Kuzmenko B, Kahel-Raifer H, Eren R, Elkeles A, Murthy KG, Szabó C, Salzman AL, Dagan S, Carmeli Y, Navon-Venezia S.

Int J Mol Med. 2005 Jul;16(1):165-71.

PMID:
15942694
22.

Facile and convenient syntheses of 6,11-dihydro-5H-indeno[1,2-c]isoquinolin- 5-ones and 6,11-dihydro-5H-indolo[3,2-c]isoquinolin-5-one.

Jagtap PG, Baloglu E, Southan G, Williams W, Roy A, Nivorozhkin A, Landrau N, Desisto K, Salzman AL, Szabó C.

Org Lett. 2005 Apr 28;7(9):1753-6.

PMID:
15844898
23.

Reduced hypoglycemia risk with insulin glargine: a meta-analysis comparing insulin glargine with human NPH insulin in type 2 diabetes.

Rosenstock J, Dailey G, Massi-Benedetti M, Fritsche A, Lin Z, Salzman A.

Diabetes Care. 2005 Apr;28(4):950-5.

PMID:
15793205
24.

Nebulized nitric oxide/nucleophile adduct reduces pulmonary vascular resistance in mechanically ventilated septicemic sheep.

Bjertnaes LJ, McGuire R, Jodoin J, Salzman AL, Traber LD, Passerini DJ, Smith DJ, Szabo C, Traber DL.

Crit Care Med. 2005 Mar;33(3):616-22.

PMID:
15753755
25.
26.

Role of poly (ADP) ribose synthetase in lung ischemia-reperfusion injury.

Woolley SM, Farivar AS, Naidu BV, Salzman A, Szabo C, Thomas R, Fraga C, Mulligan MS.

J Heart Lung Transplant. 2004 Nov;23(11):1290-6.

PMID:
15539128
27.

The ATP-sensitive potassium-channel inhibitor glibenclamide improves outcome in an ovine model of hemorrhagic shock.

Maybauer DM, Salsbury JR, Westphal M, Maybauer MO, Salzman AL, Szabó C, Westphal-Varghese BB, Traber LD, Traber DL.

Shock. 2004 Oct;22(4):387-91.

PMID:
15377897
28.

Poly (ADP) ribose synthetase inhibition reduces obliterative airway disease in rat tracheal allografts.

Farivar AS, Woolley SM, Naidu BV, Fraga CH, Byrne K, Thomas R, Salzman AL, Szabo CS, Mulligan MS.

J Heart Lung Transplant. 2004 Aug;23(8):993-1002.

PMID:
15312830
29.

Intratracheal poly (ADP) ribose synthetase inhibition ameliorates lung ischemia reperfusion injury.

Farivar AS, Woolley SM, Fraga CH, Thomas R, Salzman AL, Szabo C, Mulligan MS.

Ann Thorac Surg. 2004 Jun;77(6):1938-43.

PMID:
15172241
31.

Poly(ADP-ribose) polymerase inhibition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke.

Komjáti K, Mabley JG, Virág L, Southan GJ, Salzman AL, Szabó C.

Int J Mol Med. 2004 Mar;13(3):373-82.

PMID:
14767566
32.

Inhibition of poly (ADP-ribose) polymerase attenuates acute lung injury in an ovine model of sepsis.

Murakami K, Enkhbaatar P, Shimoda K, Cox RA, Burke AS, Hawkins HK, Traber LD, Schmalstieg FC, Salzman AL, Mabley JG, Komjáti K, Pacher P, Zsengellér Z, Szabó C, Traber DL.

Shock. 2004 Feb;21(2):126-33.

PMID:
14752285
33.

Winter warming.

Salzman A.

Rehab Manag. 2003 Dec;16(10):14-5, 44. No abstract available.

PMID:
14743674
34.

The discovery and synthesis of novel adenosine substituted 2,3-dihydro-1H-isoindol-1-ones: potent inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1).

Jagtap PG, Southan GJ, Baloglu E, Ram S, Mabley JG, Marton A, Salzman A, Szabó C.

Bioorg Med Chem Lett. 2004 Jan 5;14(1):81-5.

PMID:
14684303
35.

Topical administration of a novel nitric oxide donor, linear polyethylenimine-nitric oxide/nucleophile adduct (DS1), selectively increases vaginal blood flow in anesthetized rats.

Pacher P, Mabley JG, Liaudet L, Evgenov OV, Southan GJ, Abdelkarim GE, Szabó C, Salzman AL.

Int J Impot Res. 2003 Dec;15(6):461-4.

PMID:
14671668
36.
37.

Parenteral administration of glipizide sodium salt, an inhibitor of adenosine triphosphate-sensitive potassium channels, prolongs short-term survival after severe controlled hemorrhage in rats.

Evgenov OV, Pacher P, Williams W, Evgenov NV, Mabley JG, Cicila J, Sikó ZB, Salzman AL, Szabó C.

Crit Care Med. 2003 Oct;31(10):2429-36.

PMID:
14530747
38.

An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors.

Pinhal-Enfield G, Ramanathan M, Hasko G, Vogel SN, Salzman AL, Boons GJ, Leibovich SJ.

Am J Pathol. 2003 Aug;163(2):711-21.

39.

Critical role of reactive nitrogen species in lung ischemia-reperfusion injury.

Naidu BV, Fraga C, Salzman AL, Szabo C, Verrier ED, Mulligan MS.

J Heart Lung Transplant. 2003 Jul;22(7):784-93.

PMID:
12873547
40.

Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes.

Mabley JG, Rabinovitch A, Suarez-Pinzon W, Haskó G, Pacher P, Power R, Southan G, Salzman A, Szabó C.

Mol Med. 2003 Mar-Apr;9(3-4):96-104.

41.

Enhanced peroxynitrite decomposition protects against experimental obliterative bronchiolitis.

Naidu BV, Farivar AS, Woolley SM, Fraga C, Salzman AL, Szabo C, Groves JT, Mulligan MS.

Exp Mol Pathol. 2003 Aug;75(1):12-7.

PMID:
12834621
42.

The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5'-N-methyluronamide, is protective in two murine models of colitis.

Mabley J, Soriano F, Pacher P, Haskó G, Marton A, Wallace R, Salzman A, Szabó C.

Eur J Pharmacol. 2003 Apr 18;466(3):323-9.

PMID:
12694816
43.

The Flagellin-TLR5 Axis: Therapeutic Opportunities.

Liaudet L, Deb A, Pacher P, Mabley JG, Murthy KG, Salzman AL, Szabo C.

Drug News Perspect. 2002 Sep;15(7):397-409.

PMID:
12677175
44.

Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep.

Shimoda K, Murakami K, Enkhbaatar P, Traber LD, Cox RA, Hawkins HK, Schmalstieg FC, Komjati K, Mabley JG, Szabo C, Salzman AL, Traber DL.

Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L240-9. Epub 2003 Mar 7.

45.

Flagellin from gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis.

Liaudet L, Szabó C, Evgenov OV, Murthy KG, Pacher P, Virág L, Mabley JG, Marton A, Soriano FG, Kirov MY, Bjertnaes LJ, Salzman AL.

Shock. 2003 Feb;19(2):131-7.

PMID:
12578121
46.

Part II: beneficial effects of the peroxynitrite decomposition catalyst FP15 in murine models of arthritis and colitis.

Mabley JG, Liaudet L, Pacher P, Southan GJ, Groves JT, Salzman AL, Szabó C.

Mol Med. 2002 Oct;8(10):581-90. Erratum in: Mol Med. 2002 Dec;8(12):885.

47.

Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst.

Szabó C, Mabley JG, Moeller SM, Shimanovich R, Pacher P, Virag L, Soriano FG, Van Duzer JH, Williams W, Salzman AL, Groves JT.

Mol Med. 2002 Oct;8(10):571-80.

48.

Aerosolized linear polyethylenimine-nitric oxide/nucleophile adduct attenuates endotoxin-induced lung injury in sheep.

Kirov MY, Evgenov OV, Kuklin VN, Virag L, Pacher P, Southan GJ, Salzman AL, Szabo C, Bjertnaes LJ.

Am J Respir Crit Care Med. 2002 Dec 1;166(11):1436-42.

PMID:
12450933
49.

Inosine reduces inflammation and improves survival in a murine model of colitis.

Mabley JG, Pacher P, Liaudet L, Soriano FG, Haskó G, Marton A, Szabo C, Salzman AL.

Am J Physiol Gastrointest Liver Physiol. 2003 Jan;284(1):G138-44. Epub 2002 Aug 28.

50.

Role of nitric oxide in acute lung inflammation: lessons learned from the inducible nitric oxide synthase knockout mouse.

Shanley TP, Zhao B, Macariola DR, Denenberg A, Salzman AL, Ward PA.

Crit Care Med. 2002 Sep;30(9):1960-8.

PMID:
12352027

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