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Immunosuppression by monocytic myeloid-derived suppressor cells in patients with pancreatic ductal carcinoma is orchestrated by STAT3.

Trovato R, Fiore A, Sartori S, Canè S, Giugno R, Cascione L, Paiella S, Salvia R, De Sanctis F, Poffe O, Anselmi C, Hofer F, Sartoris S, Piro G, Carbone C, Corbo V, Lawlor R, Solito S, Pinton L, Mandruzzato S, Bassi C, Scarpa A, Bronte V, Ugel S.

J Immunother Cancer. 2019 Sep 18;7(1):255. doi: 10.1186/s40425-019-0734-6.


Unmet needs in preoperative biliary stenting for patient candidates for pancreaticoduodenectomy: a viewpoint.

Paiella S, De Pastena M, Salvia R.

Hepatobiliary Surg Nutr. 2019 Aug;8(4):426-427. doi: 10.21037/hbsn.2019.02.07. No abstract available.


"Trivial" Cysts Redefine the Risk of Cancer in Presumed Branch-Duct Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Potential Target for Follow-Up Discontinuation?

Marchegiani G, Andrianello S, Pollini T, Caravati A, Biancotto M, Secchettin E, Bonamini D, Malleo G, Bassi C, Salvia R.

Am J Gastroenterol. 2019 Aug 22. doi: 10.14309/ajg.0000000000000378. [Epub ahead of print]


Preoperative fecal elastase-1 (FE-1) adds value in predicting post-operative pancreatic fistula: not all soft pancreas share the same risk - A prospective analysis on 105 patients.

Giuliani T, Andrianello S, Bortolato C, Marchegiani G, De Marchi G, Malleo G, Frulloni L, Bassi C, Salvia R.

HPB (Oxford). 2019 Aug 13. pii: S1365-182X(19)30628-8. doi: 10.1016/j.hpb.2019.07.012. [Epub ahead of print]


Liquid Biopsy as Surrogate for Tissue for Molecular Profiling in Pancreatic Cancer: A Meta-Analysis Towards Precision Medicine.

Luchini C, Veronese N, Nottegar A, Cappelletti V, Daidone MG, Smith L, Parris C, Brosens LAA, Caruso MG, Cheng L, Wolfgang CL, Wood LD, Milella M, Salvia R, Scarpa A.

Cancers (Basel). 2019 Aug 10;11(8). pii: E1152. doi: 10.3390/cancers11081152. Review.


Outcomes of Primary Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma.

Maggino L, Malleo G, Marchegiani G, Viviani E, Nessi C, Ciprani D, Esposito A, Landoni L, Casetti L, Tuveri M, Paiella S, Casciani F, Sereni E, Binco A, Bonamini D, Secchettin E, Auriemma A, Merz V, Simionato F, Zecchetto C, D'Onofrio M, Melisi D, Bassi C, Salvia R.

JAMA Surg. 2019 Jul 24. doi: 10.1001/jamasurg.2019.2277. [Epub ahead of print]


A multimodality test to guide the management of patients with a pancreatic cyst.

Springer S, Masica DL, Dal Molin M, Douville C, Thoburn CJ, Afsari B, Li L, Cohen JD, Thompson E, Allen PJ, Klimstra DS, Schattner MA, Schmidt CM, Yip-Schneider M, Simpson RE, Fernandez-Del Castillo C, Mino-Kenudson M, Brugge W, Brand RE, Singhi AD, Scarpa A, Lawlor R, Salvia R, Zamboni G, Hong SM, Hwang DW, Jang JY, Kwon W, Swan N, Geoghegan J, Falconi M, Crippa S, Doglioni C, Paulino J, Schulick RD, Edil BH, Park W, Yachida S, Hijioka S, van Hooft J, He J, Weiss MJ, Burkhart R, Makary M, Canto MI, Goggins MG, Ptak J, Dobbyn L, Schaefer J, Sillman N, Popoli M, Klein AP, Tomasetti C, Karchin R, Papadopoulos N, Kinzler KW, Vogelstein B, Wolfgang CL, Hruban RH, Lennon AM.

Sci Transl Med. 2019 Jul 17;11(501). pii: eaav4772. doi: 10.1126/scitranslmed.aav4772.


Solid Pseudopapillary Neoplasms of the Pancreas: Clinicopathologic and Radiologic Features According to Size.

De Robertis R, Marchegiani G, Catania M, Ambrosetti MC, Capelli P, Salvia R, D'Onofrio M.

AJR Am J Roentgenol. 2019 Jul 16:1-8. doi: 10.2214/AJR.18.20715. [Epub ahead of print]


Perioperative outcomes and long-term quality of life after total pancreatectomy.

Pulvirenti A, Pea A, Rezaee N, Gasparini C, Malleo G, Weiss MJ, Cameron JL, Wolfgang CL, He J, Salvia R.

Br J Surg. 2019 Jul 8. doi: 10.1002/bjs.11185. [Epub ahead of print]


Aphidius ervi Teratocytes Release Enolase and Fatty Acid Binding Protein Through Exosomal Vesicles.

Salvia R, Grimaldi A, Girardello R, Scieuzo C, Scala A, Bufo SA, Vogel H, Falabella P.

Front Physiol. 2019 Jun 19;10:715. doi: 10.3389/fphys.2019.00715. eCollection 2019.


Comment on "Main Duct Dilatation Is the Best Predictor of High-grade Dysplasia or Invasion in Intraductal Papillary Mucinous Neoplasms of the Pancreas".

Bassi C, Marchegiani G, Malleo G, Andrianello S, Salvia R.

Ann Surg. 2019 Jun 19. doi: 10.1097/SLA.0000000000003260. [Epub ahead of print] No abstract available.


Ecdysteroidogenesis in Heliothis virescens (Lepidoptera: Noctuidae): Recombinant Prothoracicotropic Hormone and Brain Extract Show Comparable Effects.

Nardiello M, Salvia R, Scala A, Scieuzo C, Bufo SA, Franco A, Vogel H, di Somma A, Duilio A, Falabella P.

J Insect Sci. 2019 May 1;19(3). pii: 23. doi: 10.1093/jisesa/iez057.


Chemical Ecology of Capnodis tenebrionis (L.) (Coleoptera: Buprestidae): Behavioral and Biochemical Strategies for Intraspecific and Host Interactions.

Bari G, Scala A, Garzone V, Salvia R, Yalcin C, Vernile P, Aresta AM, Facini O, Baraldi R, Bufo SA, Vogel H, de Lillo E, Rapparini F, Falabella P.

Front Physiol. 2019 May 27;10:604. doi: 10.3389/fphys.2019.00604. eCollection 2019.


Role of Adjuvant Multimodality Therapy After Curative-Intent Resection of Ampullary Carcinoma.

Ecker BL, Vollmer CM Jr, Behrman SW, Allegrini V, Aversa J, Ball CG, Barrows CE, Berger AC, Cagigas MN, Christein JD, Dixon E, Fisher WE, Freedman-Weiss M, Guzman-Pruneda F, Hollis RH, House MG, Kent TS, Kowalsky SJ, Malleo G, Salem RR, Salvia R, Schmidt CR, Seykora TF, Zheng R, Zureikat AH, Dickson PV.

JAMA Surg. 2019 May 29. doi: 10.1001/jamasurg.2019.1170. [Epub ahead of print]


Association between macroscopically visible tissue samples and diagnostic accuracy of EUS-guided through-the-needle microforceps biopsy sampling of pancreatic cystic lesions.

Crinò SF, Bernardoni L, Brozzi L, Barresi L, Malleo G, Salvia R, Frulloni L, Sina S, Parisi A, Remo A, Larghi A, Gabbrielli A, Manfrin E.

Gastrointest Endosc. 2019 May 14. pii: S0016-5107(19)31690-6. doi: 10.1016/j.gie.2019.05.009. [Epub ahead of print]


Decoding Grade B Pancreatic Fistula: A Clinical and Economical Analysis and Subclassification Proposal.

Maggino L, Malleo G, Bassi C, Allegrini V, McMillan MT, Borin A, Chen B, Drebin JA, Ecker BL, Fraker DL, Lee MK, Paiella S, Roses RE, Salvia R, Vollmer CM Jr.

Ann Surg. 2019 Jun;269(6):1146-1153. doi: 10.1097/SLA.0000000000002673.


Long term outcome after minimally invasive and open Warshaw and Kimura techniques for spleen-preserving distal pancreatectomy: International multicenter retrospective study.

Paiella S, De Pastena M, Korrel M, Pan TL, Butturini G, Nessi C, De Robertis R, Landoni L, Casetti L, Giardino A, Busch O, Pea A, Esposito A, Besselink M, Bassi C, Salvia R.

Eur J Surg Oncol. 2019 Sep;45(9):1668-1673. doi: 10.1016/j.ejso.2019.04.004. Epub 2019 Apr 8.


Residual pancreatic function after pancreaticoduodenectomy is better preserved with pancreaticojejunostomy than pancreaticogastrostomy: A long-term analysis.

Benini L, Gabbrielli A, Cristofori C, Amodio A, Butturini G, Cardobi N, Sozzi C, Frulloni L, Mucelli RP, Crinò S, Bassi C, Marchegiani G, Andrianello S, Malleo G, Salvia R.

Pancreatology. 2019 Jun;19(4):595-601. doi: 10.1016/j.pan.2019.04.004. Epub 2019 Apr 16.


Beetles as Model Organisms in Physiological, Biomedical and Environmental Studies - A Review.

Adamski Z, Bufo SA, Chowański S, Falabella P, Lubawy J, Marciniak P, Pacholska-Bogalska J, Salvia R, Scrano L, Słocińska M, Spochacz M, Szymczak M, Urbański A, Walkowiak-Nowicka K, Rosiński G.

Front Physiol. 2019 Mar 28;10:319. doi: 10.3389/fphys.2019.00319. eCollection 2019. Review.


Reinforced stapler versus ultrasonic dissector for pancreatic transection and stump closure for distal pancreatectomy: A propensity matched analysis.

Pulvirenti A, Landoni L, Borin A, De Pastena M, Fontana M, Pea A, Esposito A, Casetti L, Tuveri M, Paiella S, Marchegiani G, Malleo G, Salvia R, Bassi C.

Surgery. 2019 Sep;166(3):271-276. doi: 10.1016/j.surg.2019.02.016. Epub 2019 Apr 9.


Defining the practice of distal pancreatectomy around the world.

Maggino L, Malleo G, Salvia R, Bassi C, Vollmer CM Jr.

HPB (Oxford). 2019 Mar 22. pii: S1365-182X(19)30101-7. doi: 10.1016/j.hpb.2019.02.016. [Epub ahead of print]


Pancreatic cancer – What's next?

Salvia R, Casciani F, Sereni E, Bassi C.

Presse Med. 2019 Mar;48(3 Pt 2):e187-e197. doi: 10.1016/j.lpm.2019.02.031. Epub 2019 Mar 14. Review. French.


Preoperative Imaging Evaluation after Downstaging of Pancreatic Ductal Adenocarcinoma: A Multi-Center Study.

Beleù A, Calabrese A, Rizzo G, Capelli P, Bellini N, Caloggero S, Calbi R, Tinazzi Martini P, De Robertis R, Carbognin G, Marchegiani G, Scarpa A, Salvia R, Bassi C, D'Onofrio M.

Cancers (Basel). 2019 Feb 25;11(2). pii: E267. doi: 10.3390/cancers11020267.


Cyst Fluid Biosignature to Predict Intraductal Papillary Mucinous Neoplasms of the Pancreas with High Malignant Potential.

Maker AV, Hu V, Kadkol SS, Hong L, Brugge W, Winter J, Yeo CJ, Hackert T, Büchler M, Lawlor RT, Salvia R, Scarpa A, Bassi C, Green S.

J Am Coll Surg. 2019 May;228(5):721-729. doi: 10.1016/j.jamcollsurg.2019.02.040. Epub 2019 Feb 19.


Reply to: Central pancreatectomy for benign or low-grade malignant pancreatic lesions - A single-center retrospective analysis of 116 cases.

Paiella S, De Pastena M, Salvia R.

Eur J Surg Oncol. 2019 Jun;45(6):1125. doi: 10.1016/j.ejso.2019.02.004. Epub 2019 Feb 8. No abstract available.


Dislocation of intra-abdominal drains after pancreatic surgery: results of a prospective observational study.

Marchegiani G, Ramera M, Viviani E, Lombardo F, Cybulski A, Chincarini M, Malleo G, Bassi C, Zamboni GA, Salvia R.

Langenbecks Arch Surg. 2019 Mar;404(2):213-222. doi: 10.1007/s00423-019-01760-7. Epub 2019 Feb 15.


Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma.

Obazee O, Archibugi L, Andriulli A, Soucek P, Małecka-Panas E, Ivanauskas A, Johnson T, Gazouli M, Pausch T, Lawlor RT, Cavestro GM, Milanetto AC, Di Leo M, Pasquali C, Hegyi P, Szentesi A, Radu CE, Gheorghe C, Theodoropoulos GE, Bergmann F, Brenner H, Vodickova L, Katzke V, Campa D, Strobel O, Kaiser J, Pezzilli R, Federici F, Mohelnikova-Duchonova B, Boggi U, Lemstrova R, Johansen JS, Bojesen SE, Chen I, Jensen BV, Capurso G, Pazienza V, Dervenis C, Sperti C, Mambrini A, Hackert T, Kaaks R, Basso D, Talar-Wojnarowska R, Maiello E, Izbicki JR, Cuk K, Saum KU, Cantore M, Kupcinskas J, Palmieri O, Delle Fave G, Landi S, Salvia R, Fogar P, Vashist YK, Scarpa A, Vodicka P, Tjaden C, Iskierka-Jazdzewska E, Canzian F.

Int J Cancer. 2019 Aug 1;145(3):686-693. doi: 10.1002/ijc.32127. Epub 2019 Feb 7.


Prognostic Role of High-Grade Tumor Budding in Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis with a Focus on Epithelial to Mesenchymal Transition.

Lawlor RT, Veronese N, Nottegar A, Malleo G, Smith L, Demurtas J, Cheng L, Wood LD, Silvestris N, Salvia R, Scarpa A, Luchini C.

Cancers (Basel). 2019 Jan 19;11(1). pii: E113. doi: 10.3390/cancers11010113. Review.


Management of Pancreatic Cystic Lesions.

Perri G, Marchegiani G, Frigerio I, Dervenis CG, Conlon KC, Bassi C, Salvia R.

Dig Surg. 2019 Jan 11:1-9. doi: 10.1159/000496509. [Epub ahead of print] Review.


Histopathologic Predictors of Survival and Recurrence in Resected Ampullary Adenocarcinoma: International Multicenter Cohort Study.

Moekotte AL, Lof S, Van Roessel S, Fontana M, Dreyer S, Shablak A, Casciani F, Mavroeidis VK, Robinson S, Khalil K, Gradinariu G, Mowbray N, Al-Sarireh B, Fusai GK, Roberts K, White S, Soonawalla Z, Jamieson NB, Salvia R, Besselink MG, Abu Hilal M.

Ann Surg. 2019 Jan 7. doi: 10.1097/SLA.0000000000003177. [Epub ahead of print]


Outcomes and Risk Score for Distal Pancreatectomy with Celiac Axis Resection (DP-CAR): An International Multicenter Analysis.

Klompmaker S, Peters NA, van Hilst J, Bassi C, Boggi U, Busch OR, Niesen W, Van Gulik TM, Javed AA, Kleeff J, Kawai M, Lesurtel M, Lombardo C, Moser AJ, Okada KI, Popescu I, Prasad R, Salvia R, Sauvanet A, Sturesson C, Weiss MJ, Zeh HJ, Zureikat AH, Yamaue H, Wolfgang CL, Hogg ME, Besselink MG; E-AHPBA DP-CAR study group.

Ann Surg Oncol. 2019 Mar;26(3):772-781. doi: 10.1245/s10434-018-07101-0. Epub 2019 Jan 4.


Ablation treatments in unresectable pancreatic cancer.

Paiella S, De Pastena M, Romeo F, D'onofrio M, Fontana M, Pea A, De Marchi G, Crinò SF, Bassi C, Salvia R.

Minerva Chir. 2019 Jun;74(3):263-269. doi: 10.23736/S0026-4733.18.07881-1. Epub 2019 Jan 2.


Evaluation of the MDACC clinical classification system for pancreatic cancer patients in an European multicenter cohort.

Uzunoglu FG, Welte MN, Gavazzi F, Maggino L, Perinel J, Salvia R, Janot M, Reeh M, Perez D, Montorsi M, Zerbi A, Adham M, Uhl W, Bassi C, Izbicki JR, Malleo G, Bockhorn M.

Eur J Surg Oncol. 2019 May;45(5):793-799. doi: 10.1016/j.ejso.2018.12.012. Epub 2018 Dec 19.


The Actual Prevalence of Symptoms in Pancreatic Cystic Neoplasms: A Prospective Propensity Matched Cohort Analysis.

Marchegiani G, Andrianello S, Miatello C, Pollini T, Secchettin E, Tedesco G, D'Onofrio M, Malleo G, Bassi C, Salvia R.

Dig Surg. 2018 Dec 12:1-8. doi: 10.1159/000495039. [Epub ahead of print]


Results of First-Round of Surveillance in Individuals at High-Risk of Pancreatic Cancer from the AISP (Italian Association for the Study of the Pancreas) Registry.

Paiella S, Capurso G, Cavestro GM, Butturini G, Pezzilli R, Salvia R, Signoretti M, Crippa S, Carrara S, Frigerio I, Bassi C, Falconi M, Iannicelli E, Giardino A, Mannucci A, Laghi A, Laghi L, Frulloni L, Zerbi A.

Am J Gastroenterol. 2019 Apr;114(4):665-670. doi: 10.1038/s41395-018-0414-z.


Novel Factors of Viral Origin Inhibit TOR Pathway Gene Expression.

Salvia R, Nardiello M, Scieuzo C, Scala A, Bufo SA, Rao A, Vogel H, Falabella P.

Front Physiol. 2018 Nov 26;9:1678. doi: 10.3389/fphys.2018.01678. eCollection 2018.


Central pancreatectomy for benign or low-grade malignant pancreatic lesions - A single-center retrospective analysis of 116 cases.

Paiella S, De Pastena M, Faustini F, Landoni L, Pollini T, Bonamini D, Giuliani T, Bassi C, Esposito A, Tuveri M, Salvia R.

Eur J Surg Oncol. 2019 May;45(5):788-792. doi: 10.1016/j.ejso.2018.11.021. Epub 2018 Nov 29.


Palliative therapy in pancreatic cancer-interventional treatment with radiofrequency ablation/irreversible electroporation.

Paiella S, De Pastena M, D'Onofrio M, Crinò SF, Pan TL, De Robertis R, Elio G, Martone E, Bassi C, Salvia R.

Transl Gastroenterol Hepatol. 2018 Oct 26;3:80. doi: 10.21037/tgh.2018.10.05. eCollection 2018. Review.


Patterns of Recurrence after Resection for Pancreatic Neuroendocrine Tumors: Who, When, and Where?

Marchegiani G, Landoni L, Andrianello S, Masini G, Cingarlini S, D'Onofrio M, De Robertis R, Davì M, Capelli P, Manfrin E, Amodio A, Paiella S, Malleo G, Damoli I, Miotto M, Bianchi B, Nessi C, Vivani E, Scarpa A, Salvia R, Bassi C.

Neuroendocrinology. 2019;108(3):161-171. doi: 10.1159/000495774. Epub 2018 Nov 27.


Pancreatic cancer arising in the remnant pancreas is not always a relapse of the preceding primary.

Luchini C, Pea A, Yu J, He J, Salvia R, Riva G, Weiss MJ, Bassi C, Cameron JL, Hruban RH, Goggins M, Wolfgang CL, Scarpa A, Wood LD, Lawlor RT.

Mod Pathol. 2019 May;32(5):659-665. doi: 10.1038/s41379-018-0183-7. Epub 2018 Nov 22.


Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis.

Luchini C, Veronese N, Nottegar A, Riva G, Pilati C, Mafficini A, Stubbs B, Simbolo M, Mombello A, Corbo V, Cheng L, Yachida S, Wood LD, Lawlor RT, Salvia R, Scarpa A.

Pancreas. 2019 Jan;48(1):70-76. doi: 10.1097/MPA.0000000000001194.


Current Definition of and Controversial Issues Regarding Postoperative Pancreatic Fistulas.

Marchegiani G, Andrianello S, Salvia R, Bassi C.

Gut Liver. 2019 Mar 15;13(2):149-153. doi: 10.5009/gnl18229. Review.


Evolving the Paradigm of Early Drain Removal Following Pancreatoduodenectomy.

Seykora TF, Maggino L, Malleo G, Lee MK 4th, Roses R, Salvia R, Bassi C, Vollmer CM Jr.

J Gastrointest Surg. 2019 Jan;23(1):135-144. doi: 10.1007/s11605-018-3959-7. Epub 2018 Nov 7.


ASO Author Reflections: Neoadjuvant Therapy Versus Upfront Resection for Pancreatic Cancer.

Andrianello S, Marchegiani G, Salvia R.

Ann Surg Oncol. 2018 Dec;25(Suppl 3):810-811. doi: 10.1245/s10434-018-6874-y. Epub 2018 Oct 29. No abstract available.


Adjuvant chemotherapy is associated with improved postoperative survival in specific subtypes of invasive intraductal papillary mucinous neoplasms (IPMN) of the pancreas: it is time for randomized controlled data.

Marchegiani G, Andrianello S, Dal Borgo C, Secchettin E, Melisi D, Malleo G, Bassi C, Salvia R.

HPB (Oxford). 2019 May;21(5):596-603. doi: 10.1016/j.hpb.2018.09.013. Epub 2018 Oct 23.


Genetic Analysis of Small Well-differentiated Pancreatic Neuroendocrine Tumors Identifies Subgroups With Differing Risks of Liver Metastases.

Pea A, Yu J, Marchionni L, Noe M, Luchini C, Pulvirenti A, de Wilde RF, Brosens LA, Rezaee N, Javed A, Gobbo S, Regi P, Salvia R, Bassi C, He J, Weiss MJ, Cameron JL, Offerhaus GJA, Hruban RH, Lawlor RT, Scarpa A, Heaphy CM, Wood LD, Wolfgang CL.

Ann Surg. 2018 Oct 17. doi: 10.1097/SLA.0000000000003022. [Epub ahead of print]


Reappraising the Concept of Conditional Survival After Pancreatectomy for Ductal Adenocarcinoma: A Bi-institutional Analysis.

Malleo G, Maggino L, Ferrone CR, Marchegiani G, Warshaw AL, Lillemoe KD, Bassi C, Castillo CF, Salvia R.

Ann Surg. 2018 Oct 17. doi: 10.1097/SLA.0000000000003083. [Epub ahead of print]


Pancreatic cystic neoplasm diagnosis: Role of imaging.

Sarno A, Tedesco G, De Robertis R, Marchegiani G, Salvia R, D'Onofrio M.

Endosc Ultrasound. 2018 Sep-Oct;7(5):297-300. doi: 10.4103/eus.eus_38_18. No abstract available.


Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas.

Amato E, Mafficini A, Hirabayashi K, Lawlor RT, Fassan M, Vicentini C, Barbi S, Delfino P, Sikora K, Rusev B, Simbolo M, Esposito I, Antonello D, Pea A, Sereni E, Ballotta M, Maggino L, Marchegiani G, Ohike N, Wood LD, Salvia R, Klöppel G, Zamboni G, Scarpa A, Corbo V.

J Pathol. 2019 Jan;247(1):123-134. doi: 10.1002/path.5180. Epub 2018 Nov 27.

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