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Pathogenicity of new BEST1 variants identified in Italian patients with best vitelliform macular dystrophy assessed by computational structural biology.

Frecer V, Iarossi G, Salvetti AP, Maltese PE, Delledonne G, Oldani M, Staurenghi G, Falsini B, Minnella AM, Ziccardi L, Magli A, Colombo L, D'Esposito F, Miertus J, Viola F, Attanasio M, Maggio E, Bertelli M.

J Transl Med. 2019 Oct 1;17(1):330. doi: 10.1186/s12967-019-2080-3.


Capsid Engineering Overcomes Barriers Toward Adeno-Associated Virus Vector-Mediated Transduction of Endothelial Cells.

Zhang L, Rossi A, Lange L, Meumann N, Koitzsch U, Christie K, Nesbit MA, Moore CBT, Hacker UT, Morgan M, Hoffmann D, Zengel J, Carette JE, Schambach A, Salvetti A, Odenthal M, Büning H.

Hum Gene Ther. 2019 Oct;30(10):1284-1296. doi: 10.1089/hum.2019.027.


Hepatitis B virus-induced modulation of liver macrophage function promotes hepatocyte infection.

Faure-Dupuy S, Delphin M, Aillot L, Dimier L, Lebossé F, Fresquet J, Parent R, Matter MS, Rivoire M, Bendriss-Vermare N, Salvetti A, Heide D, Flores L, Klumpp K, Lam A, Zoulim F, Heikenwälder M, Durantel D, Lucifora J.

J Hepatol. 2019 Jul 23. pii: S0168-8278(19)30422-2. doi: 10.1016/j.jhep.2019.06.032. [Epub ahead of print]


Incidence of herpes zoster and postherpetic neuralgia in Italian adults aged ≥50 years: A prospective study.

Salvetti A, Ferrari V, Garofalo R, Gazzaniga P, Guerroni A, Metrucci A, Sessa A, Severi ML, Nati G, Ruggeri M, Rossi A, Cappellari L, Gopala K, Tosatto R, Simone B.

Prev Med Rep. 2019 Apr 24;14:100882. doi: 10.1016/j.pmedr.2019.100882. eCollection 2019 Jun.


A Randomized Crossover Study to Assess the Usability of Two New Vision Tests in Patients with Low Vision.

Jolly JK, Gray JM, Salvetti AP, Han RC, MacLaren RE.

Optom Vis Sci. 2019 Jun;96(6):443-452. doi: 10.1097/OPX.0000000000001380.


Recommendations for surveillance and follow-up of men with testicular germ cell tumors: a multidisciplinary consensus conference by the Italian Germ cell cancer Group and the Associazione Italiana di Oncologia Medica.

Banna GL, Nicolai N, Palmieri G, Ottaviano M, Balzarini L, Barone D, Basso U, Bavila A, Bertoni F, Calliada F, Cai T, Carrafiello G, Condello C, Da Pozzo L, Di Nardo D, Fornarini G, Prayer Galetti T, Garolla A, Giannatempo P, Guerra L, La Spina S, Malatino L, Marchiano' A, Monti M, Morbiato FF, Morelli F, Nole' F, Palazzi S, Procopio G, Rosti G, Sacco C, Salvetti A, Salvioni R, Sava T, Secondino S, Serpentini S, Spreafico C, Tavolini IM, Valcamonico F, Verri E, Zucali P, De Giorgi U.

Crit Rev Oncol Hematol. 2019 May;137:154-164. doi: 10.1016/j.critrevonc.2019.03.006. Epub 2019 Mar 20. Review.


Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity.

Rossi A, Dupaty L, Aillot L, Zhang L, Gallien C, Hallek M, Odenthal M, Adriouch S, Salvetti A, Büning H.

Sci Rep. 2019 Mar 6;9(1):3631. doi: 10.1038/s41598-019-40071-1.


Near-Infrared Autofluorescence in Choroideremia: Anatomic and Functional Correlations.

Birtel J, Salvetti AP, Jolly JK, Xue K, Gliem M, Müller PL, Holz FG, MacLaren RE, Charbel Issa P.

Am J Ophthalmol. 2019 Mar;199:19-27. doi: 10.1016/j.ajo.2018.10.021. Epub 2018 Oct 26.


Antitumoral effects of attenuated Listeria monocytogenes in a genetically engineered mouse model of melanoma.

Vitiello M, Evangelista M, Di Lascio N, Kusmic C, Massa A, Orso F, Sarti S, Marranci A, Rodzik K, Germelli L, Chandra D, Salvetti A, Pucci A, Taverna D, Faita F, Gravekamp C, Poliseno L.

Oncogene. 2019 May;38(19):3756-3762. doi: 10.1038/s41388-019-0681-1. Epub 2019 Jan 21.


mTOR Modulates Methamphetamine-Induced Toxicity through Cell Clearing Systems.

Lazzeri G, Biagioni F, Fulceri F, Busceti CL, Scavuzzo MC, Ippolito C, Salvetti A, Lenzi P, Fornai F.

Oxid Med Cell Longev. 2018 Oct 29;2018:6124745. doi: 10.1155/2018/6124745. eCollection 2018.


Exploring the Variable Phenotypes of RPGR Carrier Females in Assessing their Potential for Retinal Gene Therapy.

Nanda A, Salvetti AP, Clouston P, Downes SM, MacLaren RE.

Genes (Basel). 2018 Dec 18;9(12). pii: E643. doi: 10.3390/genes9120643.


Investigating the neuroprotective effect of AAV-mediated β-synuclein overexpression in a transgenic model of synucleinopathy.

Sargent D, Bétemps D, Drouyer M, Verchere J, Gaillard D, Arsac JN, Lakhdar L, Salvetti A, Baron T.

Sci Rep. 2018 Dec 3;8(1):17563. doi: 10.1038/s41598-018-35825-2.


Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia.

Xue K, Jolly JK, Barnard AR, Rudenko A, Salvetti AP, Patrício MI, Edwards TL, Groppe M, Orlans HO, Tolmachova T, Black GC, Webster AR, Lotery AJ, Holder GE, Downes SM, Seabra MC, MacLaren RE.

Nat Med. 2018 Oct;24(10):1507-1512. doi: 10.1038/s41591-018-0185-5. Epub 2018 Oct 8.


Development of a yeast-based system to identify new hBRAFV600E functional interactors.

Lubrano S, Comelli L, Piccirilli C, Marranci A, Dapporto F, Tantillo E, Gemignani F, Gutkind JS, Salvetti A, Chiorino G, Cozza G, Chiariello M, Galli A, Poliseno L, Cervelli T.

Oncogene. 2019 Feb;38(8):1355-1366. doi: 10.1038/s41388-018-0496-5. Epub 2018 Sep 20.


[The multiple functions of the hepatitis B virus core protein: new research directions and therapeutic challenges].

Chabrolles H, Lahlali T, Auclair H, Salvetti A.

Med Sci (Paris). 2018 Aug-Sep;34(8-9):693-700. doi: 10.1051/medsci/20183408016. Epub 2018 Sep 19. Review. French.


Gene therapy for the treatment of X-linked retinitis pigmentosa.

Martinez-Fernandez De La Camara C, Nanda A, Salvetti AP, Fischer MD, MacLaren RE.

Expert Opin Orphan Drugs. 2018 Feb 27;6(3):167-177. doi: 10.1080/21678707.2018.1444476.


Characterization of Pattern Recognition Receptor Expression and Functionality in Liver Primary Cells and Derived Cell Lines.

Faure-Dupuy S, Vegna S, Aillot L, Dimier L, Esser K, Broxtermann M, Bonnin M, Bendriss-Vermare N, Rivoire M, Passot G, Lesurtel M, Mabrut JY, Ducerf C, Salvetti A, Protzer U, Zoulim F, Durantel D, Lucifora J.

J Innate Immun. 2018;10(4):339-348. doi: 10.1159/000489966. Epub 2018 Jul 5.


[The ISG20 protein, a new restriction factor against hepatitis B virus?]

Chardès B, Lucifora J, Salvetti A.

Med Sci (Paris). 2018 May;34(5):388-391. doi: 10.1051/medsci/20183405006. Epub 2018 Jun 13. French. No abstract available.


Characterization of AAV vector particle stability at the single-capsid level.

Bernaud J, Rossi A, Fis A, Gardette L, Aillot L, Büning H, Castelnovo M, Salvetti A, Faivre-Moskalenko C.

J Biol Phys. 2018 Jun;44(2):181-194. doi: 10.1007/s10867-018-9488-5. Epub 2018 Apr 14.


Insight into stem cell regulation from sub-lethally irradiated worms.

Rossi L, Cassella L, Iacopetti P, Ghezzani C, Tana L, Gimenez G, Ghigo E, Salvetti A.

Gene. 2018 Jul 1;662:37-45. doi: 10.1016/j.gene.2018.04.009. Epub 2018 Apr 6.


Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes.

Lucifora J, Bonnin M, Aillot L, Fusil F, Maadadi S, Dimier L, Michelet M, Floriot O, Ollivier A, Rivoire M, Ait-Goughoulte M, Daffis S, Fletcher SP, Salvetti A, Cosset FL, Zoulim F, Durantel D.

Sci Rep. 2018 Mar 29;8(1):5390. doi: 10.1038/s41598-018-23525-w.


Planarian stem cell niche, the challenge for understanding tissue regeneration.

Rossi L, Salvetti A.

Semin Cell Dev Biol. 2019 Mar;87:30-36. doi: 10.1016/j.semcdb.2018.03.005. Epub 2018 Mar 15. Review.


Misdiagnosis of X-linked retinitis pigmentosa in a choroideremia patient with heavily pigmented fundi.

Nanda A, Salvetti AP, Martinez-Fernandez de la Camara C, MacLaren RE.

Ophthalmic Genet. 2018 Jun;39(3):380-383. doi: 10.1080/13816810.2018.1430242. Epub 2018 Jan 29.


New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection.

Bellusci L, Laurino A, Sabatini M, Sestito S, Lenzi P, Raimondi L, Rapposelli S, Biagioni F, Fornai F, Salvetti A, Rossi L, Zucchi R, Chiellini G.

Front Pharmacol. 2017 Dec 12;8:905. doi: 10.3389/fphar.2017.00905. eCollection 2017.


Host and symbiont intraspecific variability: The case of Paramecium calkinsi and "Candidatus Trichorickettsia mobilis".

Sabaneyeva E, Castelli M, Szokoli F, Benken K, Lebedeva N, Salvetti A, Schweikert M, Fokin S, Petroni G.

Eur J Protistol. 2018 Feb;62:79-94. doi: 10.1016/j.ejop.2017.12.002. Epub 2017 Dec 9.


Putrescine independent wound response phenotype is produced by ODC-like RNAi in planarians.

Cassella L, Salvetti A, Iacopetti P, Ippolito C, Ghezzani C, Gimenez G, Ghigo E, Rossi L.

Sci Rep. 2017 Aug 29;7(1):9736. doi: 10.1038/s41598-017-09567-6.


Technique of retinal gene therapy: delivery of viral vector into the subretinal space.

Xue K, Groppe M, Salvetti AP, MacLaren RE.

Eye (Lond). 2017 Sep;31(9):1308-1316. doi: 10.1038/eye.2017.158. Epub 2017 Aug 18.


Detection of the hepatitis B virus (HBV) covalently-closed-circular DNA (cccDNA) in mice transduced with a recombinant AAV-HBV vector.

Lucifora J, Salvetti A, Marniquet X, Mailly L, Testoni B, Fusil F, Inchauspé A, Michelet M, Michel ML, Levrero M, Cortez P, Baumert TF, Cosset FL, Challier C, Zoulim F, Durantel D.

Antiviral Res. 2017 Sep;145:14-19. doi: 10.1016/j.antiviral.2017.07.006. Epub 2017 Jul 11.


Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis.

Salvetti AP, Patrício MI, Barnard AR, Orlans HO, Hickey DG, MacLaren RE.

Transl Vis Sci Technol. 2017 Jul 10;6(4):4. doi: 10.1167/tvst.6.4.4. eCollection 2017 Jul.


Chlorophyll derivatives enhance invertebrate red-light and ultraviolet phototaxis.

Degl'Innocenti A, Rossi L, Salvetti A, Marino A, Meloni G, Mazzolai B, Ciofani G.

Sci Rep. 2017 Jun 13;7(1):3374. doi: 10.1038/s41598-017-03247-1.


A novel mutation in the dominantly inherited TOPORS gene supports haploinsufficiency as the mechanism of retinitis pigmentosa.

Latasiewicz M, Salvetti AP, MacLaren RE.

Ophthalmic Genet. 2017 Dec;38(6):562-566. doi: 10.1080/13816810.2017.1313994. Epub 2017 Apr 28.


Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells.

Vitiello M, Tuccoli A, D'Aurizio R, Sarti S, Giannecchini L, Lubrano S, Marranci A, Evangelista M, Peppicelli S, Ippolito C, Barravecchia I, Guzzolino E, Montagnani V, Gowen M, Mercoledi E, Mercatanti A, Comelli L, Gurrieri S, Wu LW, Ope O, Flaherty K, Boland GM, Hammond MR, Kwong L, Chiariello M, Stecca B, Zhang G, Salvetti A, Angeloni D, Pitto L, Calorini L, Chiorino G, Pellegrini M, Herlyn M, Osman I, Poliseno L.

Oncotarget. 2017 Apr 11;8(15):25395-25417. doi: 10.18632/oncotarget.15915.


The Autophagoproteasome a Novel Cell Clearing Organelle in Baseline and Stimulated Conditions.

Lenzi P, Lazzeri G, Biagioni F, Busceti CL, Gambardella S, Salvetti A, Fornai F.

Front Neuroanat. 2016 Jul 21;10:78. doi: 10.3389/fnana.2016.00078. eCollection 2016.


Herpes simplex virus 1 induces egress channels through marginalized host chromatin.

Myllys M, Ruokolainen V, Aho V, Smith EA, Hakanen S, Peri P, Salvetti A, Timonen J, Hukkanen V, Larabell CA, Vihinen-Ranta M.

Sci Rep. 2016 Jun 28;6:28844. doi: 10.1038/srep28844.


Nuclear Functions of Nucleolin through Global Proteomics and Interactomic Approaches.

Salvetti A, Couté Y, Epstein A, Arata L, Kraut A, Navratil V, Bouvet P, Greco A.

J Proteome Res. 2016 May 6;15(5):1659-69. doi: 10.1021/acs.jproteome.6b00126. Epub 2016 Apr 21.


Endogenous bacterial endophthalmitis masquerading as an intraocular tumor.

Salvetti AP, Pellegrini M, Bottoni F, Staurenghi G.

Saudi J Ophthalmol. 2016 Jan-Mar;30(1):71-4. doi: 10.1016/j.sjopt.2015.11.003. Epub 2015 Nov 23.


[Integration of AAV vectors and insertional mutagenesis].

Rossi A, Salvetti A.

Med Sci (Paris). 2016 Feb;32(2):167-74. doi: 10.1051/medsci/20163202010. Epub 2016 Mar 2. Review. French.


[Viral zoonoses and emergence: research is just starting].

Salvetti A, Baize S.

Med Sci (Paris). 2015 Dec;31(12):1055-6. doi: 10.1051/medsci/20153112001. Epub 2015 Dec 16. French. No abstract available.


Oral-tolerization Prevents Immune Responses and Improves Transgene Persistence Following Gene Transfer Mediated by Adeno-associated Viral Vector.

Hardet R, Chevalier B, Dupaty L, Naïmi Y, Riou G, Drouot L, Jean L, Salvetti A, Boyer O, Adriouch S.

Mol Ther. 2016 Feb;24(1):87-95. doi: 10.1038/mt.2015.146. Epub 2015 Aug 12.


Impact of the MRN Complex on Adeno-Associated Virus Integration and Replication during Coinfection with Herpes Simplex Virus 1.

Millet R, Jolinon N, Nguyen XN, Berger G, Cimarelli A, Greco A, Bertrand P, Odenthal M, Büning H, Salvetti A.

J Virol. 2015 Jul;89(13):6824-34. doi: 10.1128/JVI.00171-15. Epub 2015 Apr 22.


In vivo biocompatibility of boron nitride nanotubes: effects on stem cell biology and tissue regeneration in planarians.

Salvetti A, Rossi L, Iacopetti P, Li X, Nitti S, Pellegrino T, Mattoli V, Golberg D, Ciofani G.

Nanomedicine (Lond). 2015 Jul;10(12):1911-22. doi: 10.2217/nnm.15.46. Epub 2015 Apr 2.


Screening in planarians identifies MORN2 as a key component in LC3-associated phagocytosis and resistance to bacterial infection.

Abnave P, Mottola G, Gimenez G, Boucherit N, Trouplin V, Torre C, Conti F, Ben Amara A, Lepolard C, Djian B, Hamaoui D, Mettouchi A, Kumar A, Pagnotta S, Bonatti S, Lepidi H, Salvetti A, Abi-Rached L, Lemichez E, Mege JL, Ghigo E.

Cell Host Microbe. 2014 Sep 10;16(3):338-50. doi: 10.1016/j.chom.2014.08.002.


Prohibitin 2 regulates cell proliferation and mitochondrial cristae morphogenesis in planarian stem cells.

Rossi L, Bonuccelli L, Iacopetti P, Evangelista M, Ghezzani C, Tana L, Salvetti A.

Stem Cell Rev Rep. 2014 Dec;10(6):871-87. doi: 10.1007/s12015-014-9540-1. Review.


[Tracking the adenovirus intracellular route during the early steps of the infectious cycle].

Rossi A, Salvetti A.

Med Sci (Paris). 2014 May;30(5):503-5. doi: 10.1051/medsci/20143005009. Epub 2014 Jun 13. French. No abstract available.


Characterization of secreted vesicles from vascular smooth muscle cells.

Comelli L, Rocchiccioli S, Smirni S, Salvetti A, Signore G, Citti L, Trivella MG, Cecchettini A.

Mol Biosyst. 2014 May;10(5):1146-52. doi: 10.1039/c3mb70544g.


AAV Vectors Vaccines Against Infectious Diseases.

Nieto K, Salvetti A.

Front Immunol. 2014 Jan 21;5:5. doi: 10.3389/fimmu.2014.00005. eCollection 2014. Review.


Hepatitis B virus infection enhances susceptibility toward adeno-associated viral vector transduction in vitro and in vivo.

Hösel M, Lucifora J, Michler T, Holz G, Gruffaz M, Stahnke S, Zoulim F, Durantel D, Heikenwalder M, Nierhoff D, Millet R, Salvetti A, Protzer U, Büning H.

Hepatology. 2014 Jun;59(6):2110-20. doi: 10.1002/hep.26990. Epub 2014 Apr 30.


Viruses and the nucleolus: the fatal attraction.

Salvetti A, Greco A.

Biochim Biophys Acta. 2014 Jun;1842(6):840-7. doi: 10.1016/j.bbadis.2013.12.010. Epub 2013 Dec 27.


Hospitalizations of cancer patients in the last month of life: quality indicator scores reveal large variation between four European countries in a mortality follow-back study.

De Roo ML, Francke AL, Van den Block L, Donker GA, Alonso JE, Miccinesi G, Moreels S, Onwuteaka-Philipsen BD, Salvetti A, Deliens L; EURO IMPACT.

BMC Palliat Care. 2014 Nov 27;13:54. doi: 10.1186/1472-684X-13-54. eCollection 2014.


Renal vasodilating capacity and endothelial function are impaired in patients with obstructive sleep apnea syndrome and no traditional cardiovascular risk factors.

Bruno RM, Rossi L, Fabbrini M, Duranti E, Di Coscio E, Maestri M, Guidi P, Frenzilli G, Salvetti A, Taddei S, Bonanni E, Ghiadoni L.

J Hypertens. 2013 Jul;31(7):1456-64; discussion 1464. doi: 10.1097/HJH.0b013e328360f773.


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