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Items: 36

1.

Machine-learning based reconstructions of primary and secondary climate variables from North American and European fossil pollen data.

Salonen JS, Korpela M, Williams JW, Luoto M.

Sci Rep. 2019 Nov 1;9(1):15805. doi: 10.1038/s41598-019-52293-4.

2.

Abrupt high-latitude climate events and decoupled seasonal trends during the Eemian.

Salonen JS, Helmens KF, Brendryen J, Kuosmanen N, Väliranta M, Goring S, Korpela M, Kylander M, Philip A, Plikk A, Renssen H, Luoto M.

Nat Commun. 2018 Jul 20;9(1):2851. doi: 10.1038/s41467-018-05314-1.

3.

Plant macrofossil evidence for an early onset of the Holocene summer thermal maximum in northernmost Europe.

Väliranta M, Salonen JS, Heikkilä M, Amon L, Helmens K, Klimaschewski A, Kuhry P, Kultti S, Poska A, Shala S, Veski S, Birks HH.

Nat Commun. 2015 Apr 10;6:6809. doi: 10.1038/ncomms7809.

4.

Proxy comparison in ancient peat sediments: pollen, macrofossil and plant DNA.

Parducci L, Väliranta M, Salonen JS, Ronkainen T, Matetovici I, Fontana SL, Eskola T, Sarala P, Suyama Y.

Philos Trans R Soc Lond B Biol Sci. 2015 Jan 19;370(1660):20130382. doi: 10.1098/rstb.2013.0382.

5.

Bioavailability of detomidine administered sublingually to horses as an oromucosal gel.

Kaukinen H, Aspegrén J, Hyyppä S, Tamm L, Salonen JS.

J Vet Pharmacol Ther. 2011 Feb;34(1):76-81. doi: 10.1111/j.1365-2885.2010.01193.x.

PMID:
21219348
6.

Regio- and stereospecific N-glucuronidation of medetomidine: the differences between UDP glucuronosyltransferase (UGT) 1A4 and UGT2B10 account for the complex kinetics of human liver microsomes.

Kaivosaari S, Toivonen P, Aitio O, Sipilä J, Koskinen M, Salonen JS, Finel M.

Drug Metab Dispos. 2008 Aug;36(8):1529-37. doi: 10.1124/dmd.108.021709. Epub 2008 May 12.

PMID:
18474681
7.

Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems.

Salonen JS, Nyman L, Boobis AR, Edwards RJ, Watts P, Lake BG, Price RJ, Renwick AB, Gómez-Lechón MJ, Castell JV, Ingelman-Sundberg M, Hidestrand M, Guillouzo A, Corcos L, Goldfarb PS, Lewis DF, Taavitsainen P, Pelkonen O.

Drug Metab Dispos. 2003 Sep;31(9):1093-102.

PMID:
12920164
8.

N-Glucuronidation of some 4-arylalkyl-1H-imidazoles by rat, dog, and human liver microsomes.

Kaivosaari S, Salonen JS, Taskinen J.

Drug Metab Dispos. 2002 Mar;30(3):295-300.

PMID:
11854148
9.

CYP2B6 and CYP2C19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of Parkinson's disease, as revealed from experiments with recombinant enzymes.

Hidestrand M, Oscarson M, Salonen JS, Nyman L, Pelkonen O, Turpeinen M, Ingelman-Sundberg M.

Drug Metab Dispos. 2001 Nov;29(11):1480-4.

PMID:
11602525
12.

Selegiline metabolism and cytochrome P450 enzymes: in vitro study in human liver microsomes.

Taavitsainen P, Anttila M, Nyman L, Karnani H, Salonen JS, Pelkonen O.

Pharmacol Toxicol. 2000 May;86(5):215-21.

PMID:
10862503
13.

Comparison of the effects of acute and subchronic administration of atipamezole on reaction to novelty and active avoidance learning in rats.

Haapalinna A, MacDonald E, Viitamaa T, Salonen JS, Sirviö J, Virtanen R.

Naunyn Schmiedebergs Arch Pharmacol. 1999 Mar;359(3):194-203.

PMID:
10208306
14.

Systemic absorption and systemic effects of ocularly administered dexmedetomidine in rabbits.

MacDonald E, Vartiainen J, Jäsberg K, Vuorilehto L, Salonen JS, Urtti A.

Curr Eye Res. 1993 May;12(5):451-60.

PMID:
8102091
15.

Identification of detomidine carboxylic acid as the major urinary metabolite of detomidine in the horse.

Salonen JS, Vuorilehto L, Gilbert M, Maylin GA.

Eur J Drug Metab Pharmacokinet. 1992 Jan-Mar;17(1):13-20.

PMID:
1499593
16.

Tissue-specificity of hydroxylation and N-methylation of arylalkylimidazoles.

Salonen JS.

Pharmacol Toxicol. 1991 Jul;69(1):1-4.

PMID:
1946187
17.

Determination of detomidine residues in horse meat by negative-ion chemical ionization mass spectrometry.

Vuorilehto L, Salonen JS, Anttila M.

J Chromatogr. 1990 Aug 24;530(1):137-40. No abstract available.

PMID:
2277103
18.
19.

Biotransformation of medetomidine in the rat.

Salonen JS, Eloranta M.

Xenobiotica. 1990 May;20(5):471-80.

PMID:
2349806
20.

Determination of the amine metabolites of selegiline in biological fluids by capillary gas chromatography.

Salonen JS.

J Chromatogr. 1990 Apr 27;527(1):163-8. No abstract available.

PMID:
2114418
21.

Picogram level determination of medetomidine in dog serum by capillary gas chromatography with negative ion chemical ionization mass spectrometry.

Vuorilehto L, Salonen JS, Anttila M.

J Chromatogr. 1989 Dec 29;497:282-7. No abstract available.

PMID:
2625465
22.

Single-dose pharmacokinetics of detomidine in the horse and cow.

Salonen JS, Vähä-Vahe T, Vainio O, Vakkuri O.

J Vet Pharmacol Ther. 1989 Mar;12(1):65-72.

PMID:
2704064
23.

Pharmacokinetics of medetomidine.

Salonen JS.

Acta Vet Scand Suppl. 1989;85:49-54.

PMID:
2571277
24.

Pharmacokinetics and metabolism of selegiline.

Heinonen EH, Myllylä V, Sotaniemi K, Lamintausta R, Salonen JS, Anttila M, Savijärvi M, Kotila M, Rinne UK.

Acta Neurol Scand Suppl. 1989;126:93-9.

PMID:
2515726
25.

Metabolism of detomidine in the rat. II. Characterisation of metabolites in urine.

Salonen JS, Vuorilehto L, Eloranta M, Karjalainen A.

Eur J Drug Metab Pharmacokinet. 1988 Jan-Mar;13(1):59-65.

PMID:
3396615
26.

Metabolism of detomidine in the rat. I. Comparison of 3H-labelled metabolites formed in vitro and in vivo.

Salonen JS, Suolinna EM.

Eur J Drug Metab Pharmacokinet. 1988 Jan-Mar;13(1):53-8.

PMID:
3396614
27.

Cardiovascular and sedative alpha-adrenoceptor effects of detomidine-like arylalkyl imidazoles and associated derivatives.

Savola JM, Ruskoaho H, Salonen JS, Puurunen J, Karjalainen A, Kurkela K, Kärki NT.

Arzneimittelforschung. 1988 Jan;38(1):29-35.

PMID:
2835056
28.

Radioimmunoassay of detomidine, a new benzylimidazole drug with analgesic sedation properties.

Vakkuri O, Salonen JS, Leppäluoto J, Anttila M, Karjalainen A, Järvensivu P.

Life Sci. 1987 Apr 6;40(14):1357-64.

PMID:
3561154
29.

Evidence for medetomidine as a selective and potent agonist at alpha 2-adrenoreceptors.

Savola JM, Ruskoaho H, Puurunen J, Salonen JS, Kärki NT.

J Auton Pharmacol. 1986 Dec;6(4):275-84.

PMID:
2880852
30.

Pharmacokinetics of detomidine.

Salonen JS.

Acta Vet Scand Suppl. 1986;82:59-66. No abstract available.

PMID:
3464183
31.

Determination of nomifensine in human serum. A comparison of high-performance liquid and gas--liquid chromatography.

Lindberg RL, Salonen JS, Iisalo EI.

J Chromatogr. 1983 Aug 12;276(1):85-92.

PMID:
6672027
32.

Improved liquid-chromatographic determination of lidocaine and its desethylated metabolites in serum.

Lindberg R, Salonen JS, Laurikainen E.

Clin Chem. 1983 Aug;29(8):1572-3. No abstract available.

33.

Determination of maprotiline and N-desmethylmaprotiline from biological fluids by HPLC.

Salonen JS, Scheinin M.

J Anal Toxicol. 1983 Jul-Aug;7(4):175-7.

PMID:
6632799
34.

Pharmacokinetics of fenclofenac in children with juvenile rheumatoid arthritis.

Mäkelä AL, Scheinin M, Iisalo E, Salonen JS.

Eur J Clin Pharmacol. 1983;25(3):381-8.

PMID:
6628527
35.

[Acute maprotiline poisoning].

Scheinin M, Engblom E, Salonen JS.

Duodecim. 1981;97(6):326-34. Finnish. No abstract available.

PMID:
7274104
36.

Radioimmunoassay for doxepin and desmethyldoxepin.

Virtanen R, Salonen JS, Scheinin M, Iisalo E, Mattila V.

Acta Pharmacol Toxicol (Copenh). 1980 Oct;47(4):274-8.

PMID:
7468227

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