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Items: 1 to 50 of 61

1.

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.

Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD.

Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021. Review.

2.

Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice.

Kasprzak KS, Diwan BA, Kaczmarek MZ, Logsdon DL, Fivash MJ, Salnikow K.

Toxicol Appl Pharmacol. 2011 Nov 15;257(1):32-7. doi: 10.1016/j.taap.2011.08.015. Epub 2011 Aug 22.

3.

Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response.

Aprelikova O, Pandolfi S, Tackett S, Ferreira M, Salnikow K, Ward Y, Risinger JI, Barrett JC, Niederhuber J.

Cancer Res. 2009 Jan 15;69(2):616-24. doi: 10.1158/0008-5472.CAN-08-0811.

4.

Metal ions-stimulated iron oxidation in hydroxylases facilitates stabilization of HIF-1 alpha protein.

Kaczmarek M, Cachau RE, Topol IA, Kasprzak KS, Ghio A, Salnikow K.

Toxicol Sci. 2009 Feb;107(2):394-403. doi: 10.1093/toxsci/kfn251. Epub 2008 Dec 13.

5.

Regulation of hypoxia-inducible genes by ETS1 transcription factor.

Salnikow K, Aprelikova O, Ivanov S, Tackett S, Kaczmarek M, Karaczyn A, Yee H, Kasprzak KS, Niederhuber J.

Carcinogenesis. 2008 Aug;29(8):1493-9. doi: 10.1093/carcin/bgn088. Epub 2008 Apr 1.

6.

Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors.

Ivanov SV, Ivanova AV, Salnikow K, Timofeeva O, Subramaniam M, Lerman MI.

Biochem Biophys Res Commun. 2008 Jun 13;370(4):536-40. doi: 10.1016/j.bbrc.2008.03.066. Epub 2008 Mar 24.

7.

Extracellular matrix and HIF-1 signaling: the role of prolidase.

Surazynski A, Donald SP, Cooper SK, Whiteside MA, Salnikow K, Liu Y, Phang JM.

Int J Cancer. 2008 Mar 15;122(6):1435-40.

8.

Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium.

Salnikow K, Zhitkovich A.

Chem Res Toxicol. 2008 Jan;21(1):28-44. Epub 2007 Oct 30. Review.

9.

Detection of changes in alveolar macrophage iron status induced by select PM2.5-associated components using iron-response protein binding activity.

Doherty SP, Prophete C, Maciejczyk P, Salnikow K, Gould T, Larson T, Koenig J, Jaques P, Sioutas C, Zelikoff JT, Lippmann M, Cohen MD.

Inhal Toxicol. 2007 May;19(6-7):553-62.

PMID:
17497533
10.

The role of ascorbate in the modulation of HIF-1alpha protein and HIF-dependent transcription by chromium(VI) and nickel(II).

Kaczmarek M, Timofeeva OA, Karaczyn A, Malyguine A, Kasprzak KS, Salnikow K.

Free Radic Biol Med. 2007 Apr 15;42(8):1246-57. Epub 2007 Jan 19.

11.

Hypoxic repression of STAT1 and its downstream genes by a pVHL/HIF-1 target DEC1/STRA13.

Ivanov SV, Salnikow K, Ivanova AV, Bai L, Lerman MI.

Oncogene. 2007 Feb 8;26(6):802-12. Epub 2006 Jul 31.

PMID:
16878149
12.

Effects of select PM-associated metals on alveolar macrophage phosphorylated ERK1 and -2 and iNOS expression during ongoing alteration in iron homeostasis.

Prophete C, Maciejczyk P, Salnikow K, Gould T, Larson T, Koenig J, Jaques P, Sioutas C, Lippmann M, Cohen M.

J Toxicol Environ Health A. 2006 May;69(10):935-51.

PMID:
16728372
13.

Quantum chemical modeling of reaction mechanism for 2-oxoglutarate dependent enzymes: effect of substitution of iron by nickel and cobalt.

Topol IA, Nemukhin AV, Salnikow K, Cachau RE, Abashkin YG, Kasprzak KS, Burt SK.

J Phys Chem A. 2006 Mar 30;110(12):4223-8.

PMID:
16553373
14.

Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel.

Karaczyn A, Ivanov S, Reynolds M, Zhitkovich A, Kasprzak KS, Salnikow K.

J Cell Biochem. 2006 Apr 1;97(5):1025-35.

PMID:
16288478
15.

Microarray analysis of altered gene expression in murine fibroblasts transformed by nickel(II) to nickel(II)-resistant malignant phenotype.

Kowara R, Karaczyn A, Cheng RY, Salnikow K, Kasprzak KS.

Toxicol Appl Pharmacol. 2005 May 15;205(1):1-10.

PMID:
15885260
16.

Ascorbate depletion: a critical step in nickel carcinogenesis?

Salnikow K, Kasprzak KS.

Environ Health Perspect. 2005 May;113(5):577-84. Review.

17.

Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain.

Zagzag D, Salnikow K, Chiriboga L, Yee H, Lan L, Ali MA, Garcia R, Demaria S, Newcomb EW.

Lab Invest. 2005 Mar;85(3):328-41.

18.

Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.

Salnikow K, Donald SP, Bruick RK, Zhitkovich A, Phang JM, Kasprzak KS.

J Biol Chem. 2004 Sep 24;279(39):40337-44. Epub 2004 Jul 22.

19.

A new intrinsic hypoxia marker in esophageal cancer.

Ding I, Okunieff P, Salnikow K, Liu W, Fenton B.

Adv Exp Med Biol. 2003;540:227-33. No abstract available.

PMID:
15174625
20.

Effect of nickel and iron co-exposure on human lung cells.

Salnikow K, Li X, Lippmann M.

Toxicol Appl Pharmacol. 2004 Apr 15;196(2):258-65.

PMID:
15081272
21.

Reduced Fhit protein expression in nickel-transformed mouse cells and in nickel-induced murine sarcomas.

Kowara R, Salnikow K, Diwan BA, Bare RM, Waalkes MP, Kasprzak KS.

Mol Cell Biochem. 2004 Jan;255(1-2):195-202.

PMID:
14971660
22.

Altered N-myc downstream-regulated gene 1 protein expression in African-American compared with caucasian prostate cancer patients.

Caruso RP, Levinson B, Melamed J, Wieczorek R, Taneja S, Polsky D, Chang C, Zeleniuch-Jacquotte A, Salnikow K, Yee H, Costa M, Osman I.

Clin Cancer Res. 2004 Jan 1;10(1 Pt 1):222-7.

23.

Nickel-induced down-regulation of serpin by hypoxic signaling.

Zhao J, Yan Y, Salnikow K, Kluz T, Costa M.

Toxicol Appl Pharmacol. 2004 Jan 1;194(1):60-8.

PMID:
14728980
24.

HIF-1: an oxygen and metal responsive transcription factor.

Maxwell P, Salnikow K.

Cancer Biol Ther. 2004 Jan;3(1):29-35. Epub 2004 Jan 10. Review.

PMID:
14726713
25.

Nickel carcinogenesis.

Kasprzak KS, Sunderman FW Jr, Salnikow K.

Mutat Res. 2003 Dec 10;533(1-2):67-97. Review.

PMID:
14643413
26.

Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel.

Davidson T, Salnikow K, Costa M.

Mol Pharmacol. 2003 Dec;64(6):1485-93.

PMID:
14645679
27.

Inhibition and reversal of nickel-induced transformation by the histone deacetylase inhibitor trichostatin A.

Zhang Q, Salnikow K, Kluz T, Chen LC, Su WC, Costa M.

Toxicol Appl Pharmacol. 2003 Nov 1;192(3):201-11.

PMID:
14575637
28.

The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis.

Salnikow K, Davidson T, Zhang Q, Chen LC, Su W, Costa M.

Cancer Res. 2003 Jul 1;63(13):3524-30.

29.
30.

GeneChip analysis of signaling pathways effected by nickel.

Salnikow K, Davidson T, Kluz T, Chen H, Zhou D, Costa M.

J Environ Monit. 2003 Apr;5(2):206-9.

PMID:
12729255
31.

Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells.

Cangul H, Salnikow K, Yee H, Zagzag D, Commes T, Costa M.

Environ Health Perspect. 2002 Oct;110 Suppl 5:783-8.

32.

The role of hypoxia-inducible signaling pathway in nickel carcinogenesis.

Salnikow K, Davidson T, Costa M.

Environ Health Perspect. 2002 Oct;110 Suppl 5:831-4.

33.

Molecular mechanisms in nickel carcinogenesis: modeling Ni(II) binding site in histone H4.

Zoroddu MA, Schinocca L, Kowalik-Jankowska T, Kozlowski H, Salnikow K, Costa M.

Environ Health Perspect. 2002 Oct;110 Suppl 5:719-23. Review.

34.

The role of oxidative stress in nickel and chromate genotoxicity.

Costa M, Salnikow K, Sutherland JE, Broday L, Peng W, Zhang Q, Kluz T.

Mol Cell Biochem. 2002 May-Jun;234-235(1-2):265-75. Review.

PMID:
12162442
35.

Molecular mechanisms of nickel carcinogenesis.

Cangul H, Broday L, Salnikow K, Sutherland J, Peng W, Zhang Q, Poltaratsky V, Yee H, Zoroddu MA, Costa M.

Toxicol Lett. 2002 Feb 28;127(1-3):69-75. Review.

PMID:
12052643
36.

Enhanced expression of a novel protein in human cancer cells: a potential aid to cancer diagnosis.

Cangul H, Salnikow K, Yee H, Zagzag D, Commes T, Costa M.

Cell Biol Toxicol. 2002;18(2):87-96.

PMID:
12046693
38.

Nickel essentiality, toxicity, and carcinogenicity.

Denkhaus E, Salnikow K.

Crit Rev Oncol Hematol. 2002 Apr;42(1):35-56. Review.

PMID:
11923067
39.

The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia.

Salnikow K, Kluz T, Costa M, Piquemal D, Demidenko ZN, Xie K, Blagosklonny MV.

Mol Cell Biol. 2002 Mar;22(6):1734-41.

40.

Backing into cancer: effects of arsenic on cell differentiation.

Salnikow K, Cohen MD.

Toxicol Sci. 2002 Feb;65(2):161-3. Review. No abstract available.

PMID:
11812918
41.

Molecular biology of nickel carcinogenesis.

Costa M, Sutherland JE, Peng W, Salnikow K, Broday L, Kluz T.

Mol Cell Biochem. 2001 Jun;222(1-2):205-11. Review.

PMID:
11678603
42.

Selective susceptibility of transformed T lymphocytes to induction of apoptosis by PSC 833, an inhibitor of P-glycoprotein.

Azare J, Pankova-Kholmyansky I, Salnikow K, Cohen D, Flescher E.

Oncol Res. 2001;12(8):315-23.

PMID:
11589302
43.

Ni(II) and Cu(II) binding with a 14-aminoacid sequence of Cap43 protein, TRSRSHTSEGTRSR.

Zoroddu MA, Kowalik-Jankowska T, Kozlowski H, Salnikow K, Costa M.

J Inorg Biochem. 2001 Mar;84(1-2):47-54. Erratum in: J Inorg Biochem 2002 Aug 15;91(2):421-2.

PMID:
11330481
44.

Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer.

Salnikow K, Costa M, Figg WD, Blagosklonny MV.

Cancer Res. 2000 Oct 15;60(20):5630-4.

45.

Epigenetic mechanisms of nickel carcinogenesis.

Salnikow K, Costa M.

J Environ Pathol Toxicol Oncol. 2000;19(3):307-18. Review.

PMID:
10983897
46.
47.

Interaction of Ni(II) and Cu(II) with a metal binding sequence of histone H4: AKRHRK, a model of the H4 tail.

Zoroddu MA, Kowalik-Jankowska T, Kozlowski H, Molinari H, Salnikow K, Broday L, Costa M.

Biochim Biophys Acta. 2000 Jul 3;1475(2):163-8.

PMID:
10832031
48.

Nickel compounds are novel inhibitors of histone H4 acetylation.

Broday L, Peng W, Kuo MH, Salnikow K, Zoroddu M, Costa M.

Cancer Res. 2000 Jan 15;60(2):238-41.

49.

Carcinogenic nickel induces genes involved with hypoxic stress.

Salnikow K, Blagosklonny MV, Ryan H, Johnson R, Costa M.

Cancer Res. 2000 Jan 1;60(1):38-41.

50.

Role of Ca(2+) in the regulation of nickel-inducible Cap43 gene expression.

Salnikow K, Kluz T, Costa M.

Toxicol Appl Pharmacol. 1999 Oct 15;160(2):127-32.

PMID:
10527911

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