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Items: 16


A Canonical Biophysical Model of the CsrA Global Regulator Suggests Flexible Regulator-Target Interactions.

Leistra AN, Gelderman G, Sowa SW, Moon-Walker A, Salis HM, Contreras LM.

Sci Rep. 2018 Jul 2;8(1):9892. doi: 10.1038/s41598-018-27474-2.


Precise quantification of translation inhibition by mRNA structures that overlap with the ribosomal footprint in N-terminal coding sequences.

Espah Borujeni A, Cetnar D, Farasat I, Smith A, Lundgren N, Salis HM.

Nucleic Acids Res. 2017 May 19;45(9):5437-5448. doi: 10.1093/nar/gkx061.


Translation Initiation is Controlled by RNA Folding Kinetics via a Ribosome Drafting Mechanism.

Espah Borujeni A, Salis HM.

J Am Chem Soc. 2016 Jun 8;138(22):7016-23. doi: 10.1021/jacs.6b01453. Epub 2016 May 26.


A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation.

Farasat I, Salis HM.

PLoS Comput Biol. 2016 Jan 29;12(1):e1004724. doi: 10.1371/journal.pcbi.1004724. eCollection 2016 Jan.


Reversing methanogenesis to capture methane for liquid biofuel precursors.

Soo VW, McAnulty MJ, Tripathi A, Zhu F, Zhang L, Hatzakis E, Smith PB, Agrawal S, Nazem-Bokaee H, Gopalakrishnan S, Salis HM, Ferry JG, Maranas CD, Patterson AD, Wood TK.

Microb Cell Fact. 2016 Jan 14;15:11. doi: 10.1186/s12934-015-0397-z.


Automated physics-based design of synthetic riboswitches from diverse RNA aptamers.

Espah Borujeni A, Mishler DM, Wang J, Huso W, Salis HM.

Nucleic Acids Res. 2016 Jan 8;44(1):1-13. doi: 10.1093/nar/gkv1289. Epub 2015 Nov 30.


A portable expression resource for engineering cross-species genetic circuits and pathways.

Kushwaha M, Salis HM.

Nat Commun. 2015 Jul 17;6:7832. doi: 10.1038/ncomms8832.


A predictive biophysical model of translational coupling to coordinate and control protein expression in bacterial operons.

Tian T, Salis HM.

Nucleic Acids Res. 2015 Aug 18;43(14):7137-51. doi: 10.1093/nar/gkv635. Epub 2015 Jun 27.


Rational design of a synthetic Entner-Doudoroff pathway for improved and controllable NADPH regeneration.

Ng CY, Farasat I, Maranas CD, Salis HM.

Metab Eng. 2015 May;29:86-96. doi: 10.1016/j.ymben.2015.03.001. Epub 2015 Mar 10.


Efficient search, mapping, and optimization of multi-protein genetic systems in diverse bacteria.

Farasat I, Kushwaha M, Collens J, Easterbrook M, Guido M, Salis HM.

Mol Syst Biol. 2014 Jun 21;10:731. doi: 10.15252/msb.20134955.


Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites.

Espah Borujeni A, Channarasappa AS, Salis HM.

Nucleic Acids Res. 2014 Feb;42(4):2646-59. doi: 10.1093/nar/gkt1139. Epub 2013 Nov 14.


The ribosome binding site calculator.

Salis HM.

Methods Enzymol. 2011;498:19-42. doi: 10.1016/B978-0-12-385120-8.00002-4.


Automated design of synthetic ribosome binding sites to control protein expression.

Salis HM, Mirsky EA, Voigt CA.

Nat Biotechnol. 2009 Oct;27(10):946-50. doi: 10.1038/nbt.1568. Epub 2009 Oct 4.


A synthetic genetic edge detection program.

Tabor JJ, Salis HM, Simpson ZB, Chevalier AA, Levskaya A, Marcotte EM, Voigt CA, Ellington AD.

Cell. 2009 Jun 26;137(7):1272-81. doi: 10.1016/j.cell.2009.04.048.


Kinetic buffering of cross talk between bacterial two-component sensors.

Groban ES, Clarke EJ, Salis HM, Miller SM, Voigt CA.

J Mol Biol. 2009 Jul 17;390(3):380-93. doi: 10.1016/j.jmb.2009.05.007. Epub 2009 May 13.

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