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Items: 41

1.

Structural Basis of Smoothened Activation in Hedgehog Signaling.

Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A.

Cell. 2018 May 15. pii: S0092-8674(18)30522-1. doi: 10.1016/j.cell.2018.04.029. [Epub ahead of print]

PMID:
29804838
2.

Lipase catalysed biodiesel synthesis with integrated glycerol separation in continuously operated microchips connected in series.

Šalić A, Tušek AJ, Sander A, Zelić B.

N Biotechnol. 2018 Feb 5. pii: S1871-6784(17)30274-1. doi: 10.1016/j.nbt.2018.01.007. [Epub ahead of print]

PMID:
29421610
3.

Sending and Receiving Hedgehog Signals.

Petrov K, Wierbowski BM, Salic A.

Annu Rev Cell Dev Biol. 2017 Oct 6;33:145-168. doi: 10.1146/annurev-cellbio-100616-060847. Epub 2017 Jul 10. Review.

PMID:
28693388
4.

Catechol Removal from Aqueous Media Using Laccase Immobilized in Different Macro- and Microreactor Systems.

Tušek AJ, Šalić A, Zelić B.

Appl Biochem Biotechnol. 2017 Aug;182(4):1575-1590. doi: 10.1007/s12010-017-2419-2. Epub 2017 Jan 23.

PMID:
28116574
5.

Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog.

Tukachinsky H, Petrov K, Watanabe M, Salic A.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5866-E5875. Epub 2016 Sep 19.

6.

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.

Huang P, Nedelcu D, Watanabe M, Jao C, Kim Y, Liu J, Salic A.

Cell. 2016 Aug 25;166(5):1176-1187.e14. doi: 10.1016/j.cell.2016.08.003. Epub 2016 Aug 18.

7.

Identification of a Paralog-Specific Notch1 Intracellular Domain Degron.

Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E.

Cell Rep. 2016 May 31;15(9):1920-9. doi: 10.1016/j.celrep.2016.04.070. Epub 2016 May 19.

8.

DyNAvectors: dynamic constitutional vectors for adaptive DNA transfection.

Clima L, Peptanariu D, Pinteala M, Salic A, Barboiu M.

Chem Commun (Camb). 2015 Dec 25;51(99):17529-31. doi: 10.1039/c5cc06715d.

PMID:
26469153
9.

Dynamic constitutional frameworks (DCFs) as nanovectors for cellular delivery of DNA.

Turin-Moleavin IA, Doroftei F, Coroaba A, Peptanariu D, Pinteala M, Salic A, Barboiu M.

Org Biomol Chem. 2015 Sep 14;13(34):9005-11. doi: 10.1039/c5ob01315a. Epub 2015 Jul 14.

PMID:
26171592
10.

Bioorthogonal probes for imaging sterols in cells.

Jao CY, Nedelcu D, Lopez LV, Samarakoon TN, Welti R, Salic A.

Chembiochem. 2015 Mar 2;16(4):611-7. doi: 10.1002/cbic.201402715. Epub 2015 Feb 6.

11.

Biosynthetic labeling and two-color imaging of phospholipids in cells.

Jao CY, Roth M, Welti R, Salic A.

Chembiochem. 2015 Feb 9;16(3):472-6. doi: 10.1002/cbic.201402149. Epub 2015 Jan 13.

PMID:
25586136
12.

Asymmetrical distribution of choline phospholipids revealed by click chemistry and freeze-fracture electron microscopy.

Iyoshi S, Cheng J, Tatematsu T, Takatori S, Taki M, Yamamoto Y, Salic A, Fujimoto T.

ACS Chem Biol. 2014 Oct 17;9(10):2217-22. doi: 10.1021/cb500558n. Epub 2014 Aug 19.

PMID:
25122546
13.

Haematopoietic stem cells require a highly regulated protein synthesis rate.

Signer RA, Magee JA, Salic A, Morrison SJ.

Nature. 2014 May 1;509(7498):49-54. doi: 10.1038/nature13035. Epub 2014 Mar 9.

14.

Bioproduction of food additives hexanal and hexanoic acid in a microreactor.

Šalić A, Pindrić K, Zelić B.

Appl Biochem Biotechnol. 2013 Dec;171(8):2273-84. doi: 10.1007/s12010-013-0495-5. Epub 2013 Sep 17.

PMID:
24043452
15.

Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling.

Nedelcu D, Liu J, Xu Y, Jao C, Salic A.

Nat Chem Biol. 2013 Sep;9(9):557-64. doi: 10.1038/nchembio.1290. Epub 2013 Jul 7.

16.

Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand.

Tukachinsky H, Kuzmickas RP, Jao CY, Liu J, Salic A.

Cell Rep. 2012 Aug 30;2(2):308-20. doi: 10.1016/j.celrep.2012.07.010. Epub 2012 Aug 16.

17.

Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin.

Liu J, Xu Y, Stoleru D, Salic A.

Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):413-8. doi: 10.1073/pnas.1111561108. Epub 2011 Dec 12.

18.

A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts.

Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, Lee LA, Robbins DJ, Huppert SS, Lee E.

J Biomol Screen. 2011 Oct;16(9):995-1006. doi: 10.1177/1087057111416657. Epub 2011 Aug 21.

19.

Processing and turnover of the Hedgehog protein in the endoplasmic reticulum.

Chen X, Tukachinsky H, Huang CH, Jao C, Chu YR, Tang HY, Mueller B, Schulman S, Rapoport TA, Salic A.

J Cell Biol. 2011 Mar 7;192(5):825-38. doi: 10.1083/jcb.201008090. Epub 2011 Feb 28.

20.

A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes.

Tukachinsky H, Lopez LV, Salic A.

J Cell Biol. 2010 Oct 18;191(2):415-28. doi: 10.1083/jcb.201004108.

21.

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.

Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, Salic A, Lee LA, Miller DM 3rd, Lee E.

Nat Chem Biol. 2010 Nov;6(11):829-36. doi: 10.1038/nchembio.453. Epub 2010 Oct 3.

22.

Metabolic labeling and direct imaging of choline phospholipids in vivo.

Jao CY, Roth M, Welti R, Salic A.

Proc Natl Acad Sci U S A. 2009 Sep 8;106(36):15332-7. doi: 10.1073/pnas.0907864106. Epub 2009 Aug 20.

23.

Exploring RNA transcription and turnover in vivo by using click chemistry.

Jao CY, Salic A.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15779-84. doi: 10.1073/pnas.0808480105. Epub 2008 Oct 7.

24.

Evidence for an upper limit to mitotic spindle length.

Wühr M, Chen Y, Dumont S, Groen AC, Needleman DJ, Salic A, Mitchison TJ.

Curr Biol. 2008 Aug 26;18(16):1256-61. doi: 10.1016/j.cub.2008.07.092.

25.

Detection of S-phase cell cycle progression using 5-ethynyl-2'-deoxyuridine incorporation with click chemistry, an alternative to using 5-bromo-2'-deoxyuridine antibodies.

Buck SB, Bradford J, Gee KR, Agnew BJ, Clarke ST, Salic A.

Biotechniques. 2008 Jun;44(7):927-9. doi: 10.2144/000112812.

26.

A chemical method for fast and sensitive detection of DNA synthesis in vivo.

Salic A, Mitchison TJ.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2415-20. doi: 10.1073/pnas.0712168105. Epub 2008 Feb 12.

27.

Lrp6 is required for convergent extension during Xenopus gastrulation.

Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E.

Development. 2007 Nov;134(22):4095-106.

28.

Bub1 is essential for assembly of the functional inner centromere.

Boyarchuk Y, Salic A, Dasso M, Arnaoutov A.

J Cell Biol. 2007 Mar 26;176(7):919-28.

29.
30.
31.

The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly.

Sampath SC, Ohi R, Leismann O, Salic A, Pozniakovski A, Funabiki H.

Cell. 2004 Jul 23;118(2):187-202.

32.

The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway.

Lee E, Salic A, Krüger R, Heinrich R, Kirschner MW.

PLoS Biol. 2003 Oct;1(1):E10. Epub 2003 Oct 13. Erratum in: PLoS Biol. 2004 Mar;2(3):E89.

33.

Anteroposterior patterning in hemichordates and the origins of the chordate nervous system.

Lowe CJ, Wu M, Salic A, Evans L, Lander E, Stange-Thomann N, Gruber CE, Gerhart J, Kirschner M.

Cell. 2003 Jun 27;113(7):853-65.

34.

A novel centrosome-associated protein with affinity for microtubules.

Stein PA, Toret CP, Salic AN, Rolls MM, Rapoport TA.

J Cell Sci. 2002 Sep 1;115(Pt 17):3389-402.

35.

A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling.

Holmen SL, Salic A, Zylstra CR, Kirschner MW, Williams BO.

J Biol Chem. 2002 Sep 20;277(38):34727-35. Epub 2002 Jul 16.

36.

Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon.

Lee E, Salic A, Kirschner MW.

J Cell Biol. 2001 Sep 3;154(5):983-93. Epub 2001 Aug 27.

37.

Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1.

Pfleger CM, Salic A, Lee E, Kirschner MW.

Genes Dev. 2001 Jul 15;15(14):1759-64.

38.

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.

Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS, Kaelin WG Jr.

Science. 2001 Apr 20;292(5516):464-8. Epub 2001 Apr 5.

39.
40.

Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation.

Kroll KL, Salic AN, Evans LM, Kirschner MW.

Development. 1998 Aug;125(16):3247-58.

41.

Sizzled: a secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos.

Salic AN, Kroll KL, Evans LM, Kirschner MW.

Development. 1997 Dec;124(23):4739-48.

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