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Items: 9


Emerging Alphaviruses Are Sensitive to Cellular States Induced by a Novel Small-Molecule Agonist of the STING Pathway.

Gall B, Pryke K, Abraham J, Mizuno N, Botto S, Sali TM, Broeckel R, Haese N, Nilsen A, Placzek A, Morrison T, Heise M, Streblow D, DeFilippis V.

J Virol. 2018 Feb 26;92(6). pii: e01913-17. doi: 10.1128/JVI.01913-17. Print 2018 Mar 15.


A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses.

Pryke KM, Abraham J, Sali TM, Gall BJ, Archer I, Liu A, Bambina S, Baird J, Gough M, Chakhtoura M, Haddad EK, Kirby IT, Nilsen A, Streblow DN, Hirsch AJ, Smith JL, DeFilippis VR.

mBio. 2017 May 2;8(3). pii: e00452-17. doi: 10.1128/mBio.00452-17.


Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses.

Sali TM, Pryke KM, Abraham J, Liu A, Archer I, Broeckel R, Staverosky JA, Smith JL, Al-Shammari A, Amsler L, Sheridan K, Nilsen A, Streblow DN, DeFilippis VR.

PLoS Pathog. 2015 Dec 8;11(12):e1005324. doi: 10.1371/journal.ppat.1005324. eCollection 2015 Dec.


Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff.

White LK, Sali T, Alvarado D, Gatti E, Pierre P, Streblow D, Defilippis VR.

J Virol. 2011 Jan;85(1):606-20. doi: 10.1128/JVI.00767-10. Epub 2010 Oct 20.


Activation of the interferon response by human cytomegalovirus occurs via cytoplasmic double-stranded DNA but not glycoprotein B.

DeFilippis VR, Sali T, Alvarado D, White L, Bresnahan W, Früh KJ.

J Virol. 2010 Sep;84(17):8913-25. doi: 10.1128/JVI.00169-10. Epub 2010 Jun 23.


Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1.

DeFilippis VR, Alvarado D, Sali T, Rothenburg S, Früh K.

J Virol. 2010 Jan;84(1):585-98. doi: 10.1128/JVI.01748-09.


Drug-induced expression of nonsteroidal anti-inflammatory drug-activated gene/macrophage inhibitory cytokine-1/prostate-derived factor, a putative tumor suppressor, inhibits tumor growth.

Martinez JM, Sali T, Okazaki R, Anna C, Hollingshead M, Hose C, Monks A, Walker NJ, Baek SJ, Eling TE.

J Pharmacol Exp Ther. 2006 Aug;318(2):899-906. Epub 2006 May 19.


Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells.

Kim JS, Baek SJ, Bottone FG Jr, Sali T, Eling TE.

Mol Cancer Res. 2005 Sep;3(9):511-7.

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