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Items: 1 to 50 of 123


Nanoparticle-based CpG-oligonucleotide therapy for treating allergic asthma.

Givens BE, Geary SM, Salem AK.

Immunotherapy. 2018 Jun;10(7):595-604. doi: 10.2217/imt-2017-0142. Epub 2018 Mar 23.


Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis.

Coleman MC, Goetz JE, Brouillette MJ, Seol D, Willey MC, Petersen EB, Anderson HD, Hendrickson NR, Compton J, Khorsand B, Morris AS, Salem AK, Fredericks DC, McKinley TO, Martin JA.

Sci Transl Med. 2018 Feb 7;10(427). pii: eaan5372. doi: 10.1126/scitranslmed.aan5372.


Combining ultrasound and intratumoral administration of doxorubicin-loaded microspheres to enhance tumor cell killing.

Do AV, Geary SM, Seol D, Tobias P, Carlsen D, Leelakanok N, Martin JA, Salem AK.

Int J Pharm. 2018 Mar 25;539(1-2):139-146. doi: 10.1016/j.ijpharm.2018.01.028. Epub 2018 Jan 17.


Synthetically lethal nanoparticles for treatment of endometrial cancer.

Ebeid K, Meng X, Thiel KW, Do AV, Geary SM, Morris AS, Pham EL, Wongrakpanich A, Chhonker YS, Murry DJ, Leslie KK, Salem AK.

Nat Nanotechnol. 2018 Jan;13(1):72-81. doi: 10.1038/s41565-017-0009-7. Epub 2017 Dec 4.


Antitumor Efficacy and Toxicity of 5-Fluorouracil-Loaded Poly(Lactide Co-glycolide) Pellets.

Leelakanok N, Geary SM, Salem AK.

J Pharm Sci. 2018 Feb;107(2):690-697. doi: 10.1016/j.xphs.2017.10.005. Epub 2017 Oct 12.


Recent Advances in Musculoskeletal Tissue Regeneration.

Salem AK.

AAPS J. 2017 Sep;19(5):1253-1254. doi: 10.1208/s12248-017-0103-7. Epub 2017 Jun 2. No abstract available.


Biomimetic Mineralization of Biomaterials Using Simulated Body Fluids for Bone Tissue Engineering and Regenerative Medicine.

Shin K, Acri T, Geary S, Salem AK.

Tissue Eng Part A. 2017 Oct;23(19-20):1169-1180. doi: 10.1089/ten.TEA.2016.0556. Epub 2017 May 22. Review.


Cationic CaMKII Inhibiting Nanoparticles Prevent Allergic Asthma.

Morris AS, Sebag SC, Paschke JD, Wongrakpanich A, Ebeid K, Anderson ME, Grumbach IM, Salem AK.

Mol Pharm. 2017 Jun 5;14(6):2166-2175. doi: 10.1021/acs.molpharmaceut.7b00114. Epub 2017 May 9.


A novel role of astrocyte elevated gene-1 (AEG-1) in regulating nonalcoholic steatohepatitis (NASH).

Srivastava J, Robertson CL, Ebeid K, Dozmorov M, Rajasekaran D, Mendoza R, Siddiq A, Akiel MA, Jariwala N, Shen XN, Windle JJ, Subler MA, Mukhopadhyay ND, Giashuddin S, Ghosh S, Lai Z, Chen Y, Fisher PB, Salem AK, Sanyal AJ, Sarkar D.

Hepatology. 2017 Aug;66(2):466-480. doi: 10.1002/hep.29230. Epub 2017 Jun 30.


Surface-modified particles loaded with CaMKII inhibitor protect cardiac cells against mitochondrial injury.

Wongrakpanich A, Morris AS, Geary SM, Joiner MA, Salem AK.

Int J Pharm. 2017 Mar 30;520(1-2):275-283. doi: 10.1016/j.ijpharm.2017.01.061. Epub 2017 Feb 3.


HPLC-UV method for simultaneous determination of MK-1775 and AZD-7762 in both acetonitrile-aqueous solution and mouse plasma.

Ebeid K, Ho GN, Salem AK.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Feb 15;1044-1045:70-76. doi: 10.1016/j.jchromb.2016.12.031. Epub 2016 Dec 30.


A Comparative Study of the Bone Regenerative Effect of Chemically Modified RNA Encoding BMP-2 or BMP-9.

Khorsand B, Elangovan S, Hong L, Dewerth A, Kormann MS, Salem AK.

AAPS J. 2017 Mar;19(2):438-446. doi: 10.1208/s12248-016-0034-8. Epub 2017 Jan 10.


Regeneration of bone using nanoplex delivery of FGF-2 and BMP-2 genes in diaphyseal long bone radial defects in a diabetic rabbit model.

Khorsand B, Nicholson N, Do AV, Femino JE, Martin JA, Petersen E, Guetschow B, Fredericks DC, Salem AK.

J Control Release. 2017 Feb 28;248:53-59. doi: 10.1016/j.jconrel.2017.01.008. Epub 2017 Jan 7.


The effect of polyanhydride chemistry in particle-based cancer vaccines on the magnitude of the anti-tumor immune response.

Wafa EI, Geary SM, Goodman JT, Narasimhan B, Salem AK.

Acta Biomater. 2017 Mar 1;50:417-427. doi: 10.1016/j.actbio.2017.01.005. Epub 2017 Jan 4.


Surface engineering tumor cells with adjuvant-loaded particles for use as cancer vaccines.

Ahmed KK, Geary SM, Salem AK.

J Control Release. 2017 Feb 28;248:1-9. doi: 10.1016/j.jconrel.2016.12.036. Epub 2017 Jan 3.


Correction: MicroRNA-200c Represses IL-6, IL-8, and CCL-5 Expression and Enhances Osteogenic Differentiation.

Hong L, Sharp T, Khorsand B, Fischer C, Eliason S, Salem AK, Akkouch A, Brogden K, Amendt BA.

PLoS One. 2016 Dec 29;11(12):e0169381. doi: 10.1371/journal.pone.0169381. eCollection 2016.


Effect of sustained PDGF nonviral gene delivery on repair of tooth-supporting bone defects.

Plonka AB, Khorsand B, Yu N, Sugai JV, Salem AK, Giannobile WV, Elangovan S.

Gene Ther. 2017 Jan;24(1):31-39. doi: 10.1038/gt.2016.73. Epub 2016 Nov 8.


Production of Adjuvant-Loaded Biodegradable Particles for Use in Cancer Vaccines.

de Barros CM, Wafa EI, Chitphet K, Ahmed K, Geary SM, Salem AK.

Methods Mol Biol. 2017;1494:201-213.


Gene-Activated Titanium Surfaces Promote In Vitro Osteogenesis.

Atluri K, Lee J, Seabold D, Elangovan S, Salem AK.

Int J Oral Maxillofac Implants. 2017 Mar/Apr;32(2):e83–e96. doi: 10.11607/jomi.5026. Epub 2016 Oct 5.


Bone Regeneration Using Gene-Activated Matrices.

D'Mello S, Atluri K, Geary SM, Hong L, Elangovan S, Salem AK.

AAPS J. 2017 Jan;19(1):43-53. doi: 10.1208/s12248-016-9982-2. Epub 2016 Sep 21. Review.


Assessing the effect of engineered nanomaterials on the environment and human health.

Geary SM, Morris AS, Salem AK.

J Allergy Clin Immunol. 2016 Aug;138(2):405-8. doi: 10.1016/j.jaci.2016.06.009. Epub 2016 Jun 27. No abstract available.


Size-dependent cytotoxicity of copper oxide nanoparticles in lung epithelial cells.

Wongrakpanich A, Mudunkotuwa IA, Geary SM, Morris AS, Mapuskar KA, Spitz DR, Grassian VH, Salem AK.

Environ Sci Nano. 2016 Apr 1;3(2):365-374. Epub 2016 Feb 24.


Corrigendum Morphological and sequence-related amplified polymorphism-based molecular diversity of local and exotic wheat genotypes - Genet. Mol. Res. 15 (2): gmr.15027484.

Abdelkhalik SM, Salem AK, Abdelaziz AR, Ammar MH.

Genet Mol Res. 2016 May 20;15(2). doi: DOI: 10.4238/gmr.15027484_corrigendum.


Controlled and Sequential Delivery of Fluorophores from 3D Printed Alginate-PLGA Tubes.

Do AV, Akkouch A, Green B, Ozbolat I, Debabneh A, Geary S, Salem AK.

Ann Biomed Eng. 2017 Jan;45(1):297-305. doi: 10.1007/s10439-016-1648-9. Epub 2016 May 27.


Morphological and sequence-related amplified polymorphism-based molecular diversity of local and exotic wheat genotypes.

Abdelkhalik SM, Salem AK, Abdelaziz AR, Ammar MH.

Genet Mol Res. 2016 Apr 28;15(2). doi: 10.4238/gmr.15027484.


Neuronal Differentiation of Induced Pluripotent Stem Cells on Surfactant Templated Chitosan Hydrogels.

Worthington KS, Green BJ, Rethwisch M, Wiley LA, Tucker BA, Guymon CA, Salem AK.

Biomacromolecules. 2016 May 9;17(5):1684-95. doi: 10.1021/acs.biomac.6b00098. Epub 2016 Apr 4.


Role of antioxidants in gestational diabetes mellitus and relation to fetal outcome: a randomized controlled trial.

Maged AM, Torky H, Fouad MA, GadAllah SH, Waked NM, Gayed AS, Salem AK.

J Matern Fetal Neonatal Med. 2016 Dec;29(24):4049-54. doi: 10.3109/14767058.2016.1154526. Epub 2016 Mar 21.


Silica Nanoparticle-Generated ROS as a Predictor of Cellular Toxicity: Mechanistic Insights and Safety by Design.

Lehman SE, Morris AS, Mueller PS, Salem AK, Grassian VH, Larsen SC.

Environ Sci Nano. 2016 Feb 1;3(1):56-66. Epub 2015 Nov 10.


The oral and craniofacial relevance of chemically modified RNA therapeutics.

Elangovan S, Kormann MS, Khorsand B, Salem AK.

Discov Med. 2016 Jan;21(113):35-9. Review.


Development and Evaluation of Biodegradable Particles Coloaded With Antigen and the Toll-Like Receptor Agonist, Pentaerythritol Lipid A, as a Cancer Vaccine.

Ahmed KK, Geary SM, Salem AK.

J Pharm Sci. 2016 Mar;105(3):1173-9. doi: 10.1016/j.xphs.2015.11.042. Epub 2016 Jan 30.


Long-term release of a thiobenzamide from a backbone functionalized poly(lactic acid).

Long TR, Wongrakpanich A, Do AV, Salem AK, Bowden NB.

Polym Chem. 2015 Oct;6(40):7188-7195. Epub 2015 Sep 4.


Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds.

Worthington KS, Wiley LA, Guymon CA, Salem AK, Tucker BA.

J Ocul Pharmacol Ther. 2016 Jun;32(5):310-6. doi: 10.1089/jop.2015.0126. Epub 2015 Dec 21.


Amine modification of nonporous silica nanoparticles reduces inflammatory response following intratracheal instillation in murine lungs.

Morris AS, Adamcakova-Dodd A, Lehman SE, Wongrakpanich A, Thorne PS, Larsen SC, Salem AK.

Toxicol Lett. 2016 Jan 22;241:207-15. doi: 10.1016/j.toxlet.2015.11.006. Epub 2015 Nov 10.


FGF2 gene activated matrices promote proliferation of bone marrow stromal cells.

D'Mello S, Elangovan S, Salem AK.

Arch Oral Biol. 2015 Dec;60(12):1742-9. doi: 10.1016/j.archoralbio.2015.09.005. Epub 2015 Sep 9.


Chemically modified RNA activated matrices enhance bone regeneration.

Elangovan S, Khorsand B, Do AV, Hong L, Dewerth A, Kormann M, Ross RD, Sumner DR, Allamargot C, Salem AK.

J Control Release. 2015 Nov 28;218:22-8. doi: 10.1016/j.jconrel.2015.09.050. Epub 2015 Sep 28.


Cytotoxicity of HBD3 for dendritic cells, normal human epidermal keratinocytes, hTERT keratinocytes, and primary oral gingival epithelial keratinocytes in cell culture conditions.

Leelakanok N, Fischer CL, Bates AM, Guthmiller JM, Johnson GK, Salem AK, Brogden KA, Brogden NK.

Toxicol Lett. 2015 Dec 3;239(2):90-6. doi: 10.1016/j.toxlet.2015.09.006. Epub 2015 Sep 11.


Diaminosulfide based polymer microparticles as cancer vaccine delivery systems.

Geary SM, Hu Q, Joshi VB, Bowden NB, Salem AK.

J Control Release. 2015 Dec 28;220(Pt B):682-90. doi: 10.1016/j.jconrel.2015.09.002. Epub 2015 Sep 8.


Nano-enabled delivery of diverse payloads across complex biological barriers.

Ross KA, Brenza TM, Binnebose AM, Phanse Y, Kanthasamy AG, Gendelman HE, Salem AK, Bartholomay LC, Bellaire BH, Narasimhan B.

J Control Release. 2015 Dec 10;219:548-559. doi: 10.1016/j.jconrel.2015.08.039. Epub 2015 Aug 24. Review.


Correlating intracellular nonviral polyplex localization with transfection efficiency using high-content screening.

Wongrakpanich A, Wu M, Salem AK.

Biotechnol Prog. 2015 Nov-Dec;31(6):1685-92. doi: 10.1002/btpr.2146. Epub 2015 Sep 23.


Nanoplex-Mediated Codelivery of Fibroblast Growth Factor and Bone Morphogenetic Protein Genes Promotes Osteogenesis in Human Adipocyte-Derived Mesenchymal Stem Cells.

Atluri K, Seabold D, Hong L, Elangovan S, Salem AK.

Mol Pharm. 2015 Aug 3;12(8):3032-42. doi: 10.1021/acs.molpharmaceut.5b00297. Epub 2015 Jul 10.


3D Printing of Scaffolds for Tissue Regeneration Applications.

Do AV, Khorsand B, Geary SM, Salem AK.

Adv Healthc Mater. 2015 Aug 26;4(12):1742-62. doi: 10.1002/adhm.201500168. Epub 2015 Jun 10. Review.


Combination of Nanoparticle-Delivered siRNA for Astrocyte Elevated Gene-1 (AEG-1) and All-trans Retinoic Acid (ATRA): An Effective Therapeutic Strategy for Hepatocellular Carcinoma (HCC).

Rajasekaran D, Srivastava J, Ebeid K, Gredler R, Akiel M, Jariwala N, Robertson CL, Shen XN, Siddiq A, Fisher PB, Salem AK, Sarkar D.

Bioconjug Chem. 2015 Aug 19;26(8):1651-61. doi: 10.1021/acs.bioconjchem.5b00254. Epub 2015 Jun 25.


Three steps to breaking immune tolerance to lymphoma: a microparticle approach.

Makkouk A, Joshi VB, Lemke CD, Wongrakpanich A, Olivier AK, Blackwell SE, Salem AK, Weiner GJ.

Cancer Immunol Res. 2015 Apr;3(4):389-98. doi: 10.1158/2326-6066.CIR-14-0173. Epub 2015 Jan 27.


Nanoparticles in vaccine delivery.

Salem AK.

AAPS J. 2015 Mar;17(2):289-91. doi: 10.1208/s12248-015-9720-1. Epub 2015 Jan 23. No abstract available.


A promising CpG adjuvant-loaded nanoparticle-based vaccine for treatment of dust mite allergies.

Salem AK.

Immunotherapy. 2014;6(11):1161-3. doi: 10.2217/imt.14.97. No abstract available.


Mitochondria-targeting particles.

Wongrakpanich A, Geary SM, Joiner ML, Anderson ME, Salem AK.

Nanomedicine (Lond). 2014 Nov;9(16):2531-43. doi: 10.2217/nnm.14.161. Review.


Biodegradable microparticles loaded with doxorubicin and CpG ODN for in situ immunization against cancer.

Makkouk A, Joshi VB, Wongrakpanich A, Lemke CD, Gross BP, Salem AK, Weiner GJ.

AAPS J. 2015 Jan;17(1):184-93. doi: 10.1208/s12248-014-9676-6. Epub 2014 Oct 18.


Incorporation of copper into chitosan scaffolds promotes bone regeneration in rat calvarial defects.

D'Mello S, Elangovan S, Hong L, Ross RD, Sumner DR, Salem AK.

J Biomed Mater Res B Appl Biomater. 2015 Jul;103(5):1044-9. doi: 10.1002/jbm.b.33290. Epub 2014 Sep 17.

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