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Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis.

Atluri K, Brouillette MJ, Seol D, Khorsand B, Sander E, Salem AK, Fredericks D, Petersen E, Smith S, Fowler TP, Martin JA.

J Orthop Res. 2019 Nov 6. doi: 10.1002/jor.24499. [Epub ahead of print]


Effects of calcium concentration on nonviral gene delivery to bone marrow-derived stem cells.

Acri TM, Laird NZ, Geary SM, Salem AK, Shin K.

J Tissue Eng Regen Med. 2019 Nov 1. doi: 10.1002/term.2971. [Epub ahead of print]


Recent Advances in Polymeric Implants.

Ahmed KK, Tamer MA, Ghareeb MM, Salem AK.

AAPS PharmSciTech. 2019 Sep 3;20(7):300. doi: 10.1208/s12249-019-1510-0. Review.


MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy.

Bi J, Areecheewakul S, Li Y, Yang S, Zhang Y, Ebeid K, Li L, Thiel KW, Zhang J, Dai D, Salem AK, Leslie KK, Meng X.

Gynecol Oncol. 2019 Nov;155(2):349-358. doi: 10.1016/j.ygyno.2019.08.014. Epub 2019 Aug 30.


Pentaerythritol-based lipid A bolsters the antitumor efficacy of a polyanhydride particle-based cancer vaccine.

Wafa EI, Geary SM, Ross KA, Goodman JT, Narasimhan B, Salem AK.

Nanomedicine. 2019 Oct;21:102055. doi: 10.1016/j.nano.2019.102055. Epub 2019 Jul 15.


3D printing in drug delivery systems.

Chakka JL, Salem AK.

J 3D Print Med. 2019 Jun;3(2):59-62. doi: 10.2217/3dp-2019-0005. Epub 2019 May 31. No abstract available.


Bullfrog oil (Rana catesbeiana Shaw) induces apoptosis, in A2058 human melanoma cells by mitochondrial dysfunction triggered by oxidative stress.

Amaral-Machado L, Oliveira WN, Alencar ÉN, Cruz AKM, Rocha HAO, Ebeid K, Salem AK, Egito EST.

Biomed Pharmacother. 2019 Sep;117:109103. doi: 10.1016/j.biopha.2019.109103. Epub 2019 Jun 14.


Sustained Release of Hydrogen Sulfide (H2S) from Poly(Lactic Acid) Functionalized 4-Hydroxythiobenzamide Microparticles to Protect Against Oxidative Damage.

Do AV, Smith R, Tobias P, Carlsen D, Pham E, Bowden NB, Salem AK.

Ann Biomed Eng. 2019 Aug;47(8):1691-1700. doi: 10.1007/s10439-019-02270-9. Epub 2019 May 28.


MicroRNA-200c Attenuates Periodontitis by Modulating Proinflammatory and Osteoclastogenic Mediators.

Akkouch A, Zhu M, Romero-Bustillos M, Eliason S, Qian F, Salem AK, Amendt BA, Hong L.

Stem Cells Dev. 2019 Aug 1;28(15):1026-1036. doi: 10.1089/scd.2019.0027. Epub 2019 May 20.


Tunable Properties of Poly-DL-Lactide-Monomethoxypolyethylene Glycol Porous Microparticles for Sustained Release of Polyethylenimine-DNA Polyplexes.

Terry TL, Givens BE, Rodgers VGJ, Salem AK.

AAPS PharmSciTech. 2019 Jan 2;20(1):23. doi: 10.1208/s12249-018-1215-9.


Improved growth of pea, lettuce, and radish plants using the slow release of hydrogen sulfide from GYY-4137.

Carter JM, Brown EM, Grace JP, Salem AK, Irish EE, Bowden NB.

PLoS One. 2018 Dec 17;13(12):e0208732. doi: 10.1371/journal.pone.0208732. eCollection 2018.


Tissue Engineering for the Temporomandibular Joint.

Acri TM, Shin K, Seol D, Laird NZ, Song I, Geary SM, Chakka JL, Martin JA, Salem AK.

Adv Healthc Mater. 2019 Jan;8(2):e1801236. doi: 10.1002/adhm.201801236. Epub 2018 Dec 17. Review.


A bioactive collagen membrane that enhances bone regeneration.

Khorsand B, Elangovan S, Hong L, Kormann MSD, Salem AK.

J Biomed Mater Res B Appl Biomater. 2019 Aug;107(6):1824-1832. doi: 10.1002/jbm.b.34275. Epub 2018 Nov 22.


Two-Photon Polymerization as a Tool for Studying 3D Printed Topography-Induced Stem Cell Fate.

Worthington KS, Do AV, Smith R, Tucker BA, Salem AK.

Macromol Biosci. 2019 Feb;19(2):e1800370. doi: 10.1002/mabi.201800370. Epub 2018 Nov 14.


Single Dose of a Polyanhydride Particle-Based Vaccine Generates Potent Antigen-Specific Antitumor Immune Responses.

Wafa EI, Geary SM, Ross KA, Goodman JT, Narasimhan B, Salem AK.

J Pharmacol Exp Ther. 2019 Sep;370(3):855-863. doi: 10.1124/jpet.118.252809. Epub 2018 Oct 25.


Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Therapeutics.

Givens BE, Naguib YW, Geary SM, Devor EJ, Salem AK.

AAPS J. 2018 Oct 10;20(6):108. doi: 10.1208/s12248-018-0267-9. Review.


Controlled drug delivery from 3D printed two-photon polymerized poly(ethylene glycol) dimethacrylate devices.

Do AV, Worthington KS, Tucker BA, Salem AK.

Int J Pharm. 2018 Dec 1;552(1-2):217-224. doi: 10.1016/j.ijpharm.2018.09.065. Epub 2018 Sep 27.


Nanoparticle-based CpG-oligonucleotide therapy for treating allergic asthma.

Givens BE, Geary SM, Salem AK.

Immunotherapy. 2018 Jun;10(7):595-604. doi: 10.2217/imt-2017-0142. Epub 2018 Mar 23. Review.


Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis.

Coleman MC, Goetz JE, Brouillette MJ, Seol D, Willey MC, Petersen EB, Anderson HD, Hendrickson NR, Compton J, Khorsand B, Morris AS, Salem AK, Fredericks DC, McKinley TO, Martin JA.

Sci Transl Med. 2018 Feb 7;10(427). pii: eaan5372. doi: 10.1126/scitranslmed.aan5372.


Combining ultrasound and intratumoral administration of doxorubicin-loaded microspheres to enhance tumor cell killing.

Do AV, Geary SM, Seol D, Tobias P, Carlsen D, Leelakanok N, Martin JA, Salem AK.

Int J Pharm. 2018 Mar 25;539(1-2):139-146. doi: 10.1016/j.ijpharm.2018.01.028. Epub 2018 Jan 17.


Synthetically lethal nanoparticles for treatment of endometrial cancer.

Ebeid K, Meng X, Thiel KW, Do AV, Geary SM, Morris AS, Pham EL, Wongrakpanich A, Chhonker YS, Murry DJ, Leslie KK, Salem AK.

Nat Nanotechnol. 2018 Jan;13(1):72-81. doi: 10.1038/s41565-017-0009-7. Epub 2017 Dec 4.


Antitumor Efficacy and Toxicity of 5-Fluorouracil-Loaded Poly(Lactide Co-glycolide) Pellets.

Leelakanok N, Geary SM, Salem AK.

J Pharm Sci. 2018 Feb;107(2):690-697. doi: 10.1016/j.xphs.2017.10.005. Epub 2017 Oct 12.


Recent Advances in Musculoskeletal Tissue Regeneration.

Salem AK.

AAPS J. 2017 Sep;19(5):1253-1254. doi: 10.1208/s12248-017-0103-7. Epub 2017 Jun 2. No abstract available.


Biomimetic Mineralization of Biomaterials Using Simulated Body Fluids for Bone Tissue Engineering and Regenerative Medicine<sup/>.

Shin K, Acri T, Geary S, Salem AK.

Tissue Eng Part A. 2017 Oct;23(19-20):1169-1180. doi: 10.1089/ten.TEA.2016.0556. Epub 2017 May 22. Review.


Cationic CaMKII Inhibiting Nanoparticles Prevent Allergic Asthma.

Morris AS, Sebag SC, Paschke JD, Wongrakpanich A, Ebeid K, Anderson ME, Grumbach IM, Salem AK.

Mol Pharm. 2017 Jun 5;14(6):2166-2175. doi: 10.1021/acs.molpharmaceut.7b00114. Epub 2017 May 9.


A novel role of astrocyte elevated gene-1 (AEG-1) in regulating nonalcoholic steatohepatitis (NASH).

Srivastava J, Robertson CL, Ebeid K, Dozmorov M, Rajasekaran D, Mendoza R, Siddiq A, Akiel MA, Jariwala N, Shen XN, Windle JJ, Subler MA, Mukhopadhyay ND, Giashuddin S, Ghosh S, Lai Z, Chen Y, Fisher PB, Salem AK, Sanyal AJ, Sarkar D.

Hepatology. 2017 Aug;66(2):466-480. doi: 10.1002/hep.29230. Epub 2017 Jun 30.


Surface-modified particles loaded with CaMKII inhibitor protect cardiac cells against mitochondrial injury.

Wongrakpanich A, Morris AS, Geary SM, Joiner MA, Salem AK.

Int J Pharm. 2017 Mar 30;520(1-2):275-283. doi: 10.1016/j.ijpharm.2017.01.061. Epub 2017 Feb 3.


HPLC-UV method for simultaneous determination of MK-1775 and AZD-7762 in both acetonitrile-aqueous solution and mouse plasma.

Ebeid K, Ho GN, Salem AK.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Feb 15;1044-1045:70-76. doi: 10.1016/j.jchromb.2016.12.031. Epub 2016 Dec 30.


A Comparative Study of the Bone Regenerative Effect of Chemically Modified RNA Encoding BMP-2 or BMP-9.

Khorsand B, Elangovan S, Hong L, Dewerth A, Kormann MS, Salem AK.

AAPS J. 2017 Mar;19(2):438-446. doi: 10.1208/s12248-016-0034-8. Epub 2017 Jan 10.


Regeneration of bone using nanoplex delivery of FGF-2 and BMP-2 genes in diaphyseal long bone radial defects in a diabetic rabbit model.

Khorsand B, Nicholson N, Do AV, Femino JE, Martin JA, Petersen E, Guetschow B, Fredericks DC, Salem AK.

J Control Release. 2017 Feb 28;248:53-59. doi: 10.1016/j.jconrel.2017.01.008. Epub 2017 Jan 7.


The effect of polyanhydride chemistry in particle-based cancer vaccines on the magnitude of the anti-tumor immune response.

Wafa EI, Geary SM, Goodman JT, Narasimhan B, Salem AK.

Acta Biomater. 2017 Mar 1;50:417-427. doi: 10.1016/j.actbio.2017.01.005. Epub 2017 Jan 4.


Surface engineering tumor cells with adjuvant-loaded particles for use as cancer vaccines.

Ahmed KK, Geary SM, Salem AK.

J Control Release. 2017 Feb 28;248:1-9. doi: 10.1016/j.jconrel.2016.12.036. Epub 2017 Jan 3.


Correction: MicroRNA-200c Represses IL-6, IL-8, and CCL-5 Expression and Enhances Osteogenic Differentiation.

Hong L, Sharp T, Khorsand B, Fischer C, Eliason S, Salem AK, Akkouch A, Brogden K, Amendt BA.

PLoS One. 2016 Dec 29;11(12):e0169381. doi: 10.1371/journal.pone.0169381. eCollection 2016.


Effect of sustained PDGF nonviral gene delivery on repair of tooth-supporting bone defects.

Plonka AB, Khorsand B, Yu N, Sugai JV, Salem AK, Giannobile WV, Elangovan S.

Gene Ther. 2017 Jan;24(1):31-39. doi: 10.1038/gt.2016.73. Epub 2016 Nov 8.


Production of Adjuvant-Loaded Biodegradable Particles for Use in Cancer Vaccines.

de Barros CM, Wafa EI, Chitphet K, Ahmed K, Geary SM, Salem AK.

Methods Mol Biol. 2017;1494:201-213.


Gene-Activated Titanium Surfaces Promote In Vitro Osteogenesis.

Atluri K, Lee J, Seabold D, Elangovan S, Salem AK.

Int J Oral Maxillofac Implants. 2017 Mar/Apr;32(2):e83–e96. doi: 10.11607/jomi.5026. Epub 2016 Oct 5.


Bone Regeneration Using Gene-Activated Matrices.

D'Mello S, Atluri K, Geary SM, Hong L, Elangovan S, Salem AK.

AAPS J. 2017 Jan;19(1):43-53. doi: 10.1208/s12248-016-9982-2. Epub 2016 Sep 21. Review.


Assessing the effect of engineered nanomaterials on the environment and human health.

Geary SM, Morris AS, Salem AK.

J Allergy Clin Immunol. 2016 Aug;138(2):405-8. doi: 10.1016/j.jaci.2016.06.009. Epub 2016 Jun 27. No abstract available.


Size-dependent cytotoxicity of copper oxide nanoparticles in lung epithelial cells.

Wongrakpanich A, Mudunkotuwa IA, Geary SM, Morris AS, Mapuskar KA, Spitz DR, Grassian VH, Salem AK.

Environ Sci Nano. 2016 Apr 1;3(2):365-374. Epub 2016 Feb 24.


Corrigendum Morphological and sequence-related amplified polymorphism-based molecular diversity of local and exotic wheat genotypes - Genet. Mol. Res. 15 (2): gmr.15027484.

Abdelkhalik SM, Salem AK, Abdelaziz AR, Ammar MH.

Genet Mol Res. 2016 May 20;15(2). doi: 10.4238/gmr.15027484_corrigendum.


Controlled and Sequential Delivery of Fluorophores from 3D Printed Alginate-PLGA Tubes.

Do AV, Akkouch A, Green B, Ozbolat I, Debabneh A, Geary S, Salem AK.

Ann Biomed Eng. 2017 Jan;45(1):297-305. doi: 10.1007/s10439-016-1648-9. Epub 2016 May 27.


Morphological and sequence-related amplified polymorphism-based molecular diversity of local and exotic wheat genotypes.

Abdelkhalik SM, Salem AK, Abdelaziz AR, Ammar MH.

Genet Mol Res. 2016 Apr 28;15(2). doi: 10.4238/gmr.15027484.


Neuronal Differentiation of Induced Pluripotent Stem Cells on Surfactant Templated Chitosan Hydrogels.

Worthington KS, Green BJ, Rethwisch M, Wiley LA, Tucker BA, Guymon CA, Salem AK.

Biomacromolecules. 2016 May 9;17(5):1684-95. doi: 10.1021/acs.biomac.6b00098. Epub 2016 Apr 4.


Role of antioxidants in gestational diabetes mellitus and relation to fetal outcome: a randomized controlled trial.

Maged AM, Torky H, Fouad MA, GadAllah SH, Waked NM, Gayed AS, Salem AK.

J Matern Fetal Neonatal Med. 2016 Dec;29(24):4049-54. doi: 10.3109/14767058.2016.1154526. Epub 2016 Mar 21.


Silica Nanoparticle-Generated ROS as a Predictor of Cellular Toxicity: Mechanistic Insights and Safety by Design.

Lehman SE, Morris AS, Mueller PS, Salem AK, Grassian VH, Larsen SC.

Environ Sci Nano. 2016 Feb 1;3(1):56-66. Epub 2015 Nov 10.


The oral and craniofacial relevance of chemically modified RNA therapeutics.

Elangovan S, Kormann MS, Khorsand B, Salem AK.

Discov Med. 2016 Jan;21(113):35-9. Review.


Development and Evaluation of Biodegradable Particles Coloaded With Antigen and the Toll-Like Receptor Agonist, Pentaerythritol Lipid A, as a Cancer Vaccine.

Ahmed KK, Geary SM, Salem AK.

J Pharm Sci. 2016 Mar;105(3):1173-9. doi: 10.1016/j.xphs.2015.11.042. Epub 2016 Jan 30.


Long-term release of a thiobenzamide from a backbone functionalized poly(lactic acid).

Long TR, Wongrakpanich A, Do AV, Salem AK, Bowden NB.

Polym Chem. 2015 Oct;6(40):7188-7195. Epub 2015 Sep 4.


Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds.

Worthington KS, Wiley LA, Guymon CA, Salem AK, Tucker BA.

J Ocul Pharmacol Ther. 2016 Jun;32(5):310-6. doi: 10.1089/jop.2015.0126. Epub 2015 Dec 21.


Amine modification of nonporous silica nanoparticles reduces inflammatory response following intratracheal instillation in murine lungs.

Morris AS, Adamcakova-Dodd A, Lehman SE, Wongrakpanich A, Thorne PS, Larsen SC, Salem AK.

Toxicol Lett. 2016 Jan 22;241:207-15. doi: 10.1016/j.toxlet.2015.11.006. Epub 2015 Nov 10.

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