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Items: 10


Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche.

Salazar VS, Capelo LP, Cant├╣ C, Zimmerli D, Gosalia N, Pregizer S, Cox K, Ohte S, Feigenson M, Gamer L, Nyman JS, Carey DJ, Economides A, Basler K, Rosen V.

Elife. 2019 Feb 8;8. pii: e42386. doi: 10.7554/eLife.42386.


N-cadherin Regulation of Bone Growth and Homeostasis Is Osteolineage Stage-Specific.

Fontana F, Hickman-Brecks CL, Salazar VS, Revollo L, Abou-Ezzi G, Grimston SK, Jeong SY, Watkins M, Fortunato M, Alippe Y, Link DC, Mbalaviele G, Civitelli R.

J Bone Miner Res. 2017 Jun;32(6):1332-1342. doi: 10.1002/jbmr.3112. Epub 2017 Mar 29.


Specification of osteoblast cell fate by canonical Wnt signaling requires Bmp2.

Salazar VS, Ohte S, Capelo LP, Gamer L, Rosen V.

Development. 2016 Dec 1;143(23):4352-4367. Epub 2016 Oct 17.


BMP signalling in skeletal development, disease and repair.

Salazar VS, Gamer LW, Rosen V.

Nat Rev Endocrinol. 2016 Apr;12(4):203-21. doi: 10.1038/nrendo.2016.12. Epub 2016 Feb 19. Review.


Loss of BMPR2 leads to high bone mass due to increased osteoblast activity.

Lowery JW, Intini G, Gamer L, Lotinun S, Salazar VS, Ote S, Cox K, Baron R, Rosen V.

J Cell Sci. 2015 Apr 1;128(7):1308-15. doi: 10.1242/jcs.156737. Epub 2015 Feb 6.


Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with ╬▓-catenin.

Salazar VS, Zarkadis N, Huang L, Watkins M, Kading J, Bonar S, Norris J, Mbalaviele G, Civitelli R.

J Cell Sci. 2013 Dec 15;126(Pt 24):5598-609. doi: 10.1242/jcs.132233. Epub 2013 Oct 7.


Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype.

Salazar VS, Zarkadis N, Huang L, Norris J, Grimston SK, Mbalaviele G, Civitelli R.

J Cell Sci. 2013 Nov 1;126(Pt 21):4974-84. doi: 10.1242/jcs.131953. Epub 2013 Sep 4.


The pro-osteogenic action of beta-catenin requires interaction with BMP signaling, but not Tcf/Lef transcriptional activity.

Salazar VS, Mbalaviele G, Civitelli R.

J Cell Biochem. 2008 Jun 1;104(3):942-52. doi: 10.1002/jcb.21679.


Beta-catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation.

Mbalaviele G, Sheikh S, Stains JP, Salazar VS, Cheng SL, Chen D, Civitelli R.

J Cell Biochem. 2005 Feb 1;94(2):403-18.


Cyclooxygenase-2 inhibition with celecoxib enhances antitumor efficacy and reduces diarrhea side effect of CPT-11.

Trifan OC, Durham WF, Salazar VS, Horton J, Levine BD, Zweifel BS, Davis TW, Masferrer JL.

Cancer Res. 2002 Oct 15;62(20):5778-84.

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