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Nature-inspired pyrrolo[2,3-d]pyrimidines targeting the histamine H3 receptor.

Frank A, Meza-Arriagada F, Salas CO, Espinosa-Bustos C, Stark H.

Bioorg Med Chem. 2019 May 29. pii: S0968-0896(19)30431-6. doi: 10.1016/j.bmc.2019.05.042. [Epub ahead of print]


Complementary and Integrative Medicine Use in Individuals Seeking Conventional Medical Oncology Care in Chile: Prevalence and Patient Characteristics.

Lopez G, Salas CA, Cadiz F, Barriga C, Gonzalez P, Acevedo S, Raimilla P, Pincheira P, Naing A, Quiroga M.

J Glob Oncol. 2019 May;5:1-6. doi: 10.1200/JGO.18.00190.


A Biomechanical Comparison of the Arciero and LaPrade Reconstruction for Posterolateral Corner Knee Injuries.

Treme GP, Salas C, Ortiz G, Gill GK, Johnson PJ, Menzer H, Richter DL, Qeadan F, Wascher DC, Schenck RC Jr.

Orthop J Sports Med. 2019 Apr 15;7(4):2325967119838251. doi: 10.1177/2325967119838251. eCollection 2019 Apr.


Acute Colchicine-induced Neuromyopathy in a Patient Treated with Atorvastatin and Clarithromycin.

Olmos-Martínez JM, Molina H, Salas C, Olmos JM, Hernández JL.

Eur J Case Rep Intern Med. 2019 Mar 18;6(3):001066. doi: 10.12890/2019_001066. eCollection 2019.


State of the art of Smo antagonists for cancer therapy: advances in the target receptor and new ligand structures.

Espinosa-Bustos C, Mella J, Soto-Delgado J, Salas CO.

Future Med Chem. 2019 Mar;11(6):617-638. doi: 10.4155/fmc-2018-0497. Epub 2019 Mar 26.


When technology cares for people with dementia: A critical review using neuropsychological rehabilitation as a conceptual framework.

Fabricatore C, Radovic D, Lopez X, Grasso-Cladera A, Salas CE.

Neuropsychol Rehabil. 2019 Mar 21:1-40. doi: 10.1080/09602011.2019.1589532. [Epub ahead of print]


Noncirrhotic portal hypertension: An under-reported late adverse event of SIRT in metastatic colorectal cancer patients.

Gutierrez L, Méndez S, Mitjavila M, Llop E, Salas C, Ruiz-Casado A.

J Cancer Res Ther. 2019 Jan-Mar;15(1):42-47. doi: 10.4103/jcrt.JCRT_1398_16.


Cisplatin resistance involves a metabolic reprogramming through ROS and PGC-1α in NSCLC which can be overcome by OXPHOS inhibition.

Cruz-Bermúdez A, Laza-Briviesca R, Vicente-Blanco RJ, García-Grande A, Coronado MJ, Laine-Menéndez S, Palacios-Zambrano S, Moreno-Villa MR, Ruiz-Valdepeñas AM, Lendinez C, Romero A, Franco F, Calvo V, Alfaro C, Acosta PM, Salas C, Garcia JM, Provencio M.

Free Radic Biol Med. 2019 May 1;135:167-181. doi: 10.1016/j.freeradbiomed.2019.03.009. Epub 2019 Mar 14.


Sociodemographic patterns of urine sodium excretion and its association with hypertension in Chile: a cross-sectional analysis.

Petermann-Rocha F, Sillars A, Brown R, Sweeney L, Troncoso C, García-Hermoso A, Leiva AM, Martínez MA, Diaz-Martínez X, Poblete-Valderrama F, Garrido-Mendez A, Cataldo X, Gonzalez JI, Salas C, Lara J, Gray SR, Celis-Morales C.

Public Health Nutr. 2019 Aug;22(11):2012-2021. doi: 10.1017/S1368980018003889. Epub 2019 Feb 14.


[Parental support for physical activity in schoolchildren and its influence on nutritional status and fitness].

Salas C, Petermann-Rocha F, Celis-Morales C, Martínez-López EJ.

Rev Chil Pediatr. 2018 Dec;89(6):732-740. doi: 10.4067/S0370-41062018005000906. Spanish.


Nonclonal Chromosome Aberrations and Genome Chaos in Somatic and Germ Cells from Patients and Survivors of Hodgkin Lymphoma.

Frias S, Ramos S, Salas C, Molina B, Sánchez S, Rivera-Luna R.

Genes (Basel). 2019 Jan 10;10(1). pii: E37. doi: 10.3390/genes10010037. Review.


Dilated Cardiomyopathy Due to BLC2-Associated Athanogene 3 (BAG3) Mutations.

Domínguez F, Cuenca S, Bilińska Z, Toro R, Villard E, Barriales-Villa R, Ochoa JP, Asselbergs F, Sammani A, Franaszczyk M, Akhtar M, Coronado-Albi MJ, Rangel-Sousa D, Rodriguez-Palomares JF, Jiménez-Jáimez J, Garcia-Pinilla JM, Ripoll-Vera T, Mogollón-Jiménez MV, Fontalba-Romero A, Garcia-Medina D, Palomino-Doza J, de Gonzalo-Calvo D, Cicerchia M, Salazar-Mendiguchia J, Salas C, Pankuweit S, Hey TM, Mogensen J, Barton PJ, Charron P, Elliott P, Garcia-Pavia P; European Genetic Cardiomyopathies Initiative Investigators.

J Am Coll Cardiol. 2018 Nov 13;72(20):2471-2481. doi: 10.1016/j.jacc.2018.08.2181.


Cancer-associated fibroblasts modify lung cancer metabolism involving ROS and TGF-β signaling.

Cruz-Bermúdez A, Laza-Briviesca R, Vicente-Blanco RJ, García-Grande A, Coronado MJ, Laine-Menéndez S, Alfaro C, Sanchez JC, Franco F, Calvo V, Romero A, Martin-Acosta P, Salas C, Garcia JM, Provencio M.

Free Radic Biol Med. 2019 Jan;130:163-173. doi: 10.1016/j.freeradbiomed.2018.10.450. Epub 2018 Nov 1.


Effect of body weight and energy intake on body composition analysis of broiler breeder hens.

Salas C, Ekmay RD, England J, Cerrate S, Coon CN.

Poult Sci. 2019 Feb 1;98(2):796-802. doi: 10.3382/ps/pey377.


Cysteine Proteases from V. cundinamarcensis (C. candamarcensis) Inhibit Melanoma Metastasis and Modulate Expression of Proteins Related to Proliferation, Migration and Differentiation.

Lemos FO, Dittz D, Santos VG, Pires SF, de Andrade HM, Salas CE, Lopes MTP.

Int J Mol Sci. 2018 Sep 20;19(10). pii: E2846. doi: 10.3390/ijms19102846.


Antifungal activity of proteolytic fraction (P1G10) from (Vasconcellea cundinamarcensis) latex inhibit cell growth and cell wall integrity in Botrytis cinerea.

Torres-Ossandón MJ, Vega-Gálvez A, Salas CE, Rubio J, Silva-Moreno E, Castillo L.

Int J Food Microbiol. 2019 Jan 16;289:7-16. doi: 10.1016/j.ijfoodmicro.2018.08.027. Epub 2018 Aug 28.


Sequence analysis of the cDNA encoding for SpCTx: a lethal factor from scorpionfish venom (Scorpaena plumieri).

Costa FLS, De Lima ME, Figueiredo SG, Ferreira RS, Prates NS, Sakamoto T, Salas CE.

J Venom Anim Toxins Incl Trop Dis. 2018 Aug 29;24:24. doi: 10.1186/s40409-018-0158-7. eCollection 2018.


Varicella in the prison setting: A report of three outbreaks in Rhode Island and a review of the literature.

Murphy M, Berns AL, Bandyopadhyay U, Rich J, Quilliam DN, Clarke J, Kane K, Salas C, Yousaf A, Reece R.

Vaccine. 2018 Sep 5;36(37):5651-5656. doi: 10.1016/j.vaccine.2018.07.031. Epub 2018 Aug 10. Review.


Incidental findings on brain MRI in a cohort of diabetic patients.

Vázquez-Justes D, Sanahuja J, Diez J, Rubinat E, Begué R, Salas C, Vicandi C, Gil MI, Purroy F, Mauricio D.

J Neuroradiol. 2018 Aug 9. pii: S0150-9861(18)30138-X. doi: 10.1016/j.neurad.2018.07.005. [Epub ahead of print]


New lead elements for histamine H3 receptor ligands in the pyrrolo[2,3-d]pyrimidine class.

Espinosa-Bustos C, Frank A, Arancibia-Opazo S, Salas CO, Fierro A, Stark H.

Bioorg Med Chem Lett. 2018 Sep 15;28(17):2890-2893. doi: 10.1016/j.bmcl.2018.07.023. Epub 2018 Jul 17.


[Measures of association in a study of risk factors associated with the development of hypertension in Chile].

Senosain-Leon V, Hidalgo A, Petermann F, Durán E, Labraña AM, Martínez MA, Leiva AM, Garrido-Méndez A, Poblete-Valderrama F, Díaz-Martínez X, Salas C, Celis-Morales C.

Rev Med Chil. 2018 Feb;146(2):267-268. doi: 10.4067/s0034-98872018000200267. Spanish. No abstract available.


[The joint effect of sitting time and obesity on the odds of developing type 2 diabetes].

Petermann F, Garrido-Méndez A, Díaz-Martínez X, Leiva AM, Martínez MA, Poblete-Valderrama F, Salas C, Cristi-Montero C, Celis-Morales C.

Rev Med Chil. 2018 Apr;146(4):433-441. doi: 10.4067/s0034-98872018000400433. Spanish. No abstract available.


What are the Most Widely used and Effective Attack Coverage Systems in Men's Volleyball?

Hileno R, García-de-Alcaraz A, Buscà B, Salas C, Camerino O.

J Hum Kinet. 2018 Jun 13;62:111-121. doi: 10.1515/hukin-2017-0163. eCollection 2018 Jun.


(-)-Shikimic Acid as a Chiral Building Block for the Synthesis of New Cytotoxic 6-Aza-Analogues of Angucyclinones.

Quiñones N, Hernández S, Espinoza Catalán L, Villena J, Brito I, Cabrera AR, Salas CO, Cuellar MA.

Molecules. 2018 Jun 12;23(6). pii: E1422. doi: 10.3390/molecules23061422.


Mental disorders and drug use in victims of the armed conflict in three cities in Colombia

Castaño G, Sierra G, Sánchez D, Torres Y, Salas C, Buitrago C.

Biomedica. 2018 May 1;38(0):70-85. doi: 10.7705/biomedica.v38i0.3890.


[Correlates of sedentary behaviors in Chile: evidence from the National Health Survey 2009-2010].

Martínez MA, Leiva AM, Petermann F, Garrido A, Díaz X, Álvarez C, Salas C, Cristi C, Rodríguez F, Aguilar N, Ramírez R, Celis C.

Rev Med Chil. 2018 Jan;146(1):22-31. doi: 10.4067/s0034-98872018000100022. Spanish.


Differences between manual and automatic analysis in determining the severity of obstructive sleep apnea using home sleep apnea testing.

Labarca G, Dreyse J, Salas C, Contreras A, Nazar G, Gaete MI, Jorquera J.

Sleep Med. 2018 Jul;47:66-71. doi: 10.1016/j.sleep.2018.03.015. Epub 2018 Apr 7.


Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence.

Ohashi M, Korsakova E, Allen D, Lee P, Fu K, Vargas BS, Cinkornpumin J, Salas C, Park JC, Germanguz I, Langerman J, Chronis C, Kuoy E, Tran S, Xiao X, Pellegrini M, Plath K, Lowry WE.

Stem Cell Reports. 2018 May 8;10(5):1453-1463. doi: 10.1016/j.stemcr.2018.04.001.


Driver distraction by smartphone use (WhatsApp) in different age groups.

Ortiz C, Ortiz-Peregrina S, Castro JJ, Casares-López M, Salas C.

Accid Anal Prev. 2018 Aug;117:239-249. doi: 10.1016/j.aap.2018.04.018. Epub 2018 May 1.


Adult Autoinmune Enteropathy and Colitis: A Challenge Successfully Treated With Adalimumab.

Relea L, Calvo M, Pons F, Salas C, Abreu L.

Inflamm Bowel Dis. 2018 Apr 23;24(5):e11. doi: 10.1093/ibd/izy105. No abstract available.


The Proteolytic Fraction from Latex of Vasconcellea cundinamarcensis (P1G10) Enhances Wound Healing of Diabetic Foot Ulcers: A Double-Blind Randomized Pilot Study.

Tonaco LAB, Gomes FL, Velasquez-Melendez G, Lopes MTP, Salas CE.

Adv Ther. 2018 Apr;35(4):494-502. doi: 10.1007/s12325-018-0684-2. Epub 2018 Mar 21.


[Increase in body mass index during the last four decades in Chile: from undernutrition to obesity].

Celis-Morales C, Leiva A, Martínez MA, Durán E, Labraña AM, Petermann F, Garrido-Mendez A, Díaz X, Salas C, Poblete-Valderrama F.

Rev Med Chil. 2017 Oct;145(10):1363-1364. doi: 10.4067/S0034-98872017001001363. Spanish. No abstract available.


Damage in a Distal Radius Fracture Model Treated With Locked Volar Plating After Simulated Postoperative Loading.

Salas C, Brantley JA, Clark J, Reda Taha M, Myers OB, Mercer D.

J Hand Surg Am. 2018 Jul;43(7):679.e1-679.e6. doi: 10.1016/j.jhsa.2017.12.019. Epub 2018 Feb 6.


Long-term Outcomes of Partial Trapeziectomy With Capsular Interposition Arthroplasty for Osteoarthritis of the Thumb Basal Joint.

Moneim MS, Salas C, Lese AB, Thompson NB, Mercer DM.

Orthopedics. 2018 Mar 1;41(2):e228-e233. doi: 10.3928/01477447-20180123-03. Epub 2018 Jan 29.


The Psychoexposome: A holistic perspective beyond health and disease.

Colomina MT, Sánchez-Santed F, Conejo NM, Collado P, Salvador A, Gallo M, Pinos H, Salas C, Navarro JF, Adán A, Azpiroz A, Arias JL.

Psicothema. 2018 Feb;30(1):5-7. doi: 10.7334/psicothema2017.244.


Renal Decapsulation Prevents Intrinsic Renal Compartment Syndrome in Ischemia-Reperfusion-Induced Acute Kidney Injury: A Physiologic Approach.

Cruces P, Lillo P, Salas C, Salomon T, Lillo F, González C, Pacheco A, Hurtado DE.

Crit Care Med. 2018 Feb;46(2):216-222. doi: 10.1097/CCM.0000000000002830.


Identification of capillary rarefaction using intracoronary wave intensity analysis with resultant prognostic implications for cardiac allograft patients.

Broyd CJ, Hernández-Pérez F, Segovia J, Echavarría-Pinto M, Quirós-Carretero A, Salas C, Gonzalo N, Jiménez-Quevedo P, Nombela-Franco L, Salinas P, Núñez-Gil I, Del Trigo M, Goicolea J, Alonso-Pulpón L, Fernández-Ortiz A, Parker K, Hughes A, Mayet J, Davies J, Escaned J.

Eur Heart J. 2018 May 21;39(20):1807-1814. doi: 10.1093/eurheartj/ehx732.


[Association between type 2 diabetes and physical activity in individuals with family history of diabetes].

Petermann F, Díaz-Martínez X, Garrido-Méndez Á, Leiva AM, Martínez MA, Salas C, Poblete-Valderrama F, Celis-Morales C.

Gac Sanit. 2018 May - Jun;32(3):230-235. doi: 10.1016/j.gaceta.2017.09.008. Epub 2017 Dec 6. Spanish.


[The economic burden of physical inactivity in Chile].

Celis-Morales C, Salas C, Martínez MA, Leiva AM, Garrido-Méndez A, Díaz-Martínez X.

Rev Med Chil. 2017 Aug;145(8):1091-1092. doi: 10.4067/s0034-98872017000801091. Spanish. No abstract available.


[Risk factors associated with hypertension. Analysis of the 2009-2010 Chilean health survey].

Petermann F, Durán E, Labraña AM, Martínez MA, Leiva AM, Garrido-Méndez A, Poblete-Valderrama F, Díaz-Martínez X, Salas C, Celis-Morales C.

Rev Med Chil. 2017 Aug;145(8):996-1004. doi: 10.4067/s0034-98872017000800996. Spanish.


[Risk factors for obesity: analysis of the 2009-2010 Chilean health survey].

Petermann F, Durán E, Labraña AM, Martínez MA, Leiva AM, Garrido-Méndez A, Poblete-Valderrama F, Díaz-Martínez X, Salas C, Celis-Morales C.

Rev Med Chil. 2017 Jun;145(6):716-722. doi: 10.4067/s0034-98872017000600716. Spanish. No abstract available.


Dynamics of Goldfish Subregional Hippocampal Pallium Activity throughout Spatial Memory Formation.

Ocaña FM, Uceda S, Arias JL, Salas C, Rodríguez F.

Brain Behav Evol. 2017;90(2):154-170. doi: 10.1159/000478843. Epub 2017 Oct 9.


Healing activity of proteolytic fraction (P1G10) from Vasconcellea cundinamarcensis in a cutaneous wound excision model.

Freitas KM, Barcelos LS, Caliari MV, Salas CE, Lopes MTP.

Biomed Pharmacother. 2017 Dec;96:269-278. doi: 10.1016/j.biopha.2017.09.109. Epub 2017 Oct 6.


[Effects of a lower body weight or waist circumference on cardiovascular risk].

Labraña AM, Durán E, Martínez MA, Leiva AM, Garrido-Méndez A, Díaz X, Salas C, Celis-Morales C.

Rev Med Chil. 2017 May;145(5):585-594. doi: 10.4067/S0034-98872017000500005. Spanish.


Observations on Working Psychoanalytically with a Profoundly Amnesic Patient.

Moore PA, Salas CE, Dockree S, Turnbull OH.

Front Psychol. 2017 Aug 25;8:1418. doi: 10.3389/fpsyg.2017.01418. eCollection 2017.


[Sedentary lifestyle is associated with metabolic and cardiovascular risk factors independent of physical activity].

Leiva AM, Martínez MA, Cristi-Montero C, Salas C, Ramírez-Campillo R, Díaz Martínez X, Aguilar-Farías N, Celis-Morales C.

Rev Med Chil. 2017 Apr;145(4):458-467. doi: 10.4067/S0034-98872017000400006. Spanish.


New imidoyl-indazole platinum (II) complexes as potential anticancer agents: Synthesis, evaluation of cytotoxicity, cell death and experimental-theoretical DNA interaction studies.

Cabrera AR, Espinosa-Bustos C, Faúndez M, Meléndez J, Jaque P, Daniliuc CG, Aguirre A, Rojas RS, Salas CO.

J Inorg Biochem. 2017 Sep;174:90-101. doi: 10.1016/j.jinorgbio.2017.06.001. Epub 2017 Jun 15.


Combined molecular modelling and 3D-QSAR study for understanding the inhibition of NQO1 by heterocyclic quinone derivatives.

López-Lira C, Alzate-Morales JH, Paulino M, Mella-Raipán J, Salas CO, Tapia RA, Soto-Delgado J.

Chem Biol Drug Des. 2018 Jan;91(1):29-38. doi: 10.1111/cbdd.13051. Epub 2017 Aug 20.


Fluorescence properties of aurone derivatives: an experimental and theoretical study with some preliminary biological applications.

Espinosa-Bustos C, Cortés-Arriagada D, Soto-Arriaza MA, Robinson-Duggon J, Pizarro N, Cabrera AR, Fuentealba D, Salas CO.

Photochem Photobiol Sci. 2017 Aug 9;16(8):1268-1276. doi: 10.1039/c7pp00078b.


Nutritional composition, antioxidant activity and isolation of scopoletin from Senecio nutans: support of ancestral and new uses.

Parra C, Soto E, León G, Salas CO, Heinrich M, Echiburú-Chau C.

Nat Prod Res. 2018 Mar;32(6):719-722. doi: 10.1080/14786419.2017.1335726. Epub 2017 Jun 6.


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