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Items: 11


Tyrosine sulfation of human trypsin steers S2' subsite selectivity towards basic amino acids.

Szabó A, Salameh MA, Ludwig M, Radisky ES, Sahin-Tóth M.

PLoS One. 2014 Jul 10;9(7):e102063. doi: 10.1371/journal.pone.0102063. eCollection 2014.


Biochemical and structural insights into mesotrypsin: an unusual human trypsin.

Salameh MA, Radisky ES.

Int J Biochem Mol Biol. 2013 Sep 13;4(3):129-39. Review.


PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.

Hockla A, Miller E, Salameh MA, Copland JA, Radisky DC, Radisky ES.

Mol Cancer Res. 2012 Dec;10(12):1555-66. doi: 10.1158/1541-7786.MCR-12-0314.


Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors.

Salameh MA, Soares AS, Alloy A, Radisky ES.

Protein Sci. 2012 Aug;21(8):1103-12. doi: 10.1002/pro.2097. Epub 2012 Jun 25.


The P(2)' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity.

Salameh MA, Soares AS, Hockla A, Radisky DC, Radisky ES.

Biochem J. 2011 Nov 15;440(1):95-105. doi: 10.1042/BJ20110788.


Determinants of affinity and proteolytic stability in interactions of Kunitz family protease inhibitors with mesotrypsin.

Salameh MA, Soares AS, Navaneetham D, Sinha D, Walsh PN, Radisky ES.

J Biol Chem. 2010 Nov 19;285(47):36884-96. doi: 10.1074/jbc.M110.171348. Epub 2010 Sep 22.


The amyloid precursor protein/protease nexin 2 Kunitz inhibitor domain is a highly specific substrate of mesotrypsin.

Salameh MA, Robinson JL, Navaneetham D, Sinha D, Madden BJ, Walsh PN, Radisky ES.

J Biol Chem. 2010 Jan 15;285(3):1939-49. doi: 10.1074/jbc.M109.057216. Epub 2009 Nov 17.


Synthesis of fatty acid esters and diacylglycerols at elevated temperatures by alkalithermophilic lipases from Thermosyntropha lipolytica.

Salameh MA, Wiegel J.

J Ind Microbiol Biotechnol. 2009 Oct;36(10):1281-7. doi: 10.1007/s10295-009-0610-3. Epub 2009 Jul 11.


Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin.

Salameh MA, Soares AS, Hockla A, Radisky ES.

J Biol Chem. 2008 Feb 15;283(7):4115-23. Epub 2007 Dec 12.


Purification and characterization of two highly thermophilic alkaline lipases from Thermosyntropha lipolytica.

Salameh MA, Wiegel J.

Appl Environ Microbiol. 2007 Dec;73(23):7725-31. Epub 2007 Oct 12.

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