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Items: 11

1.

The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.

Sala Frigerio C, Wolfs L, Fattorelli N, Thrupp N, Voytyuk I, Schmidt I, Mancuso R, Chen WT, Woodbury ME, Srivastava G, Möller T, Hudry E, Das S, Saido T, Karran E, Hyman B, Perry VH, Fiers M, De Strooper B.

Cell Rep. 2019 Apr 23;27(4):1293-1306.e6. doi: 10.1016/j.celrep.2019.03.099.

2.

Alzheimer's Disease Mechanisms and Emerging Roads to Novel Therapeutics.

Sala Frigerio C, De Strooper B.

Annu Rev Neurosci. 2016 Jul 8;39:57-79. doi: 10.1146/annurev-neuro-070815-014015. Epub 2016 Apr 4. Review.

PMID:
27050320
3.

N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42.

Szczepankiewicz O, Linse B, Meisl G, Thulin E, Frohm B, Sala Frigerio C, Colvin MT, Jacavone AC, Griffin RG, Knowles T, Walsh DM, Linse S.

J Am Chem Soc. 2015 Nov 25;137(46):14673-85. doi: 10.1021/jacs.5b07849. Epub 2015 Nov 17.

4.

On the identification of low allele frequency mosaic mutations in the brains of Alzheimer's disease patients.

Sala Frigerio C, Lau P, Troakes C, Deramecourt V, Gele P, Van Loo P, Voet T, De Strooper B.

Alzheimers Dement. 2015 Nov;11(11):1265-76. doi: 10.1016/j.jalz.2015.02.007. Epub 2015 Apr 29.

PMID:
25937274
5.

A self-organizing miR-132/Ctbp2 circuit regulates bimodal notch signals and glial progenitor fate choice during spinal cord maturation.

Salta E, Lau P, Sala Frigerio C, Coolen M, Bally-Cuif L, De Strooper B.

Dev Cell. 2014 Aug 25;30(4):423-36. doi: 10.1016/j.devcel.2014.07.006. Epub 2014 Aug 14.

6.

Reduced expression of hsa-miR-27a-3p in CSF of patients with Alzheimer disease.

Sala Frigerio C, Lau P, Salta E, Tournoy J, Bossers K, Vandenberghe R, Wallin A, Bjerke M, Zetterberg H, Blennow K, De Strooper B.

Neurology. 2013 Dec 10;81(24):2103-6. doi: 10.1212/01.wnl.0000437306.37850.22. Epub 2013 Nov 8.

PMID:
24212398
7.

Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation.

Borlikova GG, Trejo M, Mably AJ, Mc Donald JM, Sala Frigerio C, Regan CM, Murphy KJ, Masliah E, Walsh DM.

Neurobiol Aging. 2013 May;34(5):1315-27. doi: 10.1016/j.neurobiolaging.2012.10.028. Epub 2012 Nov 22.

8.

beta-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins.

Sala Frigerio C, Fadeeva JV, Minogue AM, Citron M, Van Leuven F, Staufenbiel M, Paganetti P, Selkoe DJ, Walsh DM.

FEBS J. 2010 Mar;277(6):1503-18. doi: 10.1111/j.1742-4658.2010.07579.x. Epub 2010 Feb 15.

9.

An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1.

Sala Frigerio C, Kukar TL, Fauq A, Engel PC, Golde TE, Walsh DM.

Biochemistry. 2009 Nov 24;48(46):10894-904. doi: 10.1021/bi901237k.

10.

The APP family of proteins: similarities and differences.

Walsh DM, Minogue AM, Sala Frigerio C, Fadeeva JV, Wasco W, Selkoe DJ.

Biochem Soc Trans. 2007 Apr;35(Pt 2):416-20.

PMID:
17371289
11.

PEN-2 gene mutation in a familial Alzheimer's disease case.

Sala Frigerio C, Piscopo P, Calabrese E, Crestini A, Malvezzi Campeggi L, Civita di Fava R, Fogliarino S, Albani D, Marcon G, Cherchi R, Piras R, Forloni G, Confaloni A.

J Neurol. 2005 Sep;252(9):1033-6. Epub 2005 Mar 16.

PMID:
16170650

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