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Items: 24


Implication of calcium activated RasGRF2 in Annexin A6-mediated breast tumor cell growth and motility.

Whalen DS, Widatalla SE, Korolkova OY, Nangami GS, Beasley HK, Williams SD, Virgous C, Lehmann BD, Ochieng J, Sakwe AM.

Oncotarget. 2019 Jan 4;10(2):133-151. doi: 10.18632/oncotarget.26512. eCollection 2019 Jan 4.


Lapatinib-induced annexin A6 upregulation as an adaptive response of triple-negative breast cancer cells to EGFR tyrosine kinase inhibitors.

Widatalla SE, Korolkova OY, Whalen DS, Goodwin JS, Williams KP, Ochieng J, Sakwe AM.

Carcinogenesis. 2019 Aug 22;40(8):998-1009. doi: 10.1093/carcin/bgy192.


PML-Nuclear Bodies Regulate the Stability of the Fusion Protein Dendra2-Nrf2 in the Nucleus.

Burroughs AF, Eluhu S, Whalen D, Goodwin JS, Sakwe AM, Arinze IJ.

Cell Physiol Biochem. 2018;47(2):800-816. doi: 10.1159/000490033. Epub 2018 May 22.


Correction: Human alpha defensin 5 is a candidate biomarker to delineate inflammatory bowel disease.

Williams AD, Korolkova OY, Sakwe AM, Geiger TM, James SD, Muldoon RL, Herline AJ, Goodwin JS, Izban MG, Washington MK, Smoot DT, Ballard BR, Gazouli M, M'Koma AE.

PLoS One. 2017 Dec 6;12(12):e0189551. doi: 10.1371/journal.pone.0189551. eCollection 2017.


Human alpha defensin 5 is a candidate biomarker to delineate inflammatory bowel disease.

Williams AD, Korolkova OY, Sakwe AM, Geiger TM, James SD, Muldoon RL, Herline AJ, Goodwin JS, Izban MG, Washington MK, Smoot DT, Ballard BR, Gazouli M, M'Koma AE.

PLoS One. 2017 Aug 17;12(8):e0179710. doi: 10.1371/journal.pone.0179710. eCollection 2017. Erratum in: PLoS One. 2017 Dec 6;12 (12 ):e0189551.


Association of calcium sensing receptor polymorphisms at rs1801725 with circulating calcium in breast cancer patients.

Wang L, Widatalla SE, Whalen DS, Ochieng J, Sakwe AM.

BMC Cancer. 2017 Aug 2;17(1):511. doi: 10.1186/s12885-017-3502-3.


Fetuin-A (alpha 2HS glycoprotein) modulates growth, motility, invasion, and senescence in high-grade astrocytomas.

Nangami GN, Sakwe AM, Izban MG, Rana T, Lammers PE, Thomas P, Chen Z, Ochieng J.

Cancer Med. 2016 Dec;5(12):3532-3543. doi: 10.1002/cam4.940. Epub 2016 Nov 23.


Fetuin-A associates with histones intracellularly and shuttles them to exosomes to promote focal adhesion assembly resulting in rapid adhesion and spreading in breast carcinoma cells.

Nangami G, Koumangoye R, Shawn Goodwin J, Sakwe AM, Marshall D, Higginbotham J, Ochieng J.

Exp Cell Res. 2014 Nov 1;328(2):388-400. doi: 10.1016/j.yexcr.2014.08.037. Epub 2014 Sep 4.


Reduced annexin A6 expression promotes the degradation of activated epidermal growth factor receptor and sensitizes invasive breast cancer cells to EGFR-targeted tyrosine kinase inhibitors.

Koumangoye RB, Nangami GN, Thompson PD, Agboto VK, Ochieng J, Sakwe AM.

Mol Cancer. 2013 Dec 19;12(1):167. doi: 10.1186/1476-4598-12-167.


Fetuin-A triggers the secretion of a novel set of exosomes in detached tumor cells that mediate their adhesion and spreading.

Watson K, Koumangoye R, Thompson P, Sakwe AM, Patel T, Pratap S, Ochieng J.

FEBS Lett. 2012 Sep 21;586(19):3458-63. doi: 10.1016/j.febslet.2012.07.071. Epub 2012 Aug 8.


The MCM-associated protein MCM-BP is important for human nuclear morphology.

Jagannathan M, Sakwe AM, Nguyen T, Frappier L.

J Cell Sci. 2012 Jan 1;125(Pt 1):133-43. doi: 10.1242/jcs.089938. Epub 2012 Jan 16.


Detachment of breast tumor cells induces rapid secretion of exosomes which subsequently mediate cellular adhesion and spreading.

Koumangoye RB, Sakwe AM, Goodwin JS, Patel T, Ochieng J.

PLoS One. 2011;6(9):e24234. doi: 10.1371/journal.pone.0024234. Epub 2011 Sep 6.


Annexin A6 contributes to the invasiveness of breast carcinoma cells by influencing the organization and localization of functional focal adhesions.

Sakwe AM, Koumangoye R, Guillory B, Ochieng J.

Exp Cell Res. 2011 Apr 1;317(6):823-37. doi: 10.1016/j.yexcr.2010.12.008. Epub 2010 Dec 24.


Fetuin-A ({alpha}2HS-glycoprotein) is a major serum adhesive protein that mediates growth signaling in breast tumor cells.

Sakwe AM, Koumangoye R, Goodwin SJ, Ochieng J.

J Biol Chem. 2010 Dec 31;285(53):41827-35. doi: 10.1074/jbc.M110.128926. Epub 2010 Oct 18.


Lack of fetuin-A (alpha2-HS-glycoprotein) reduces mammary tumor incidence and prolongs tumor latency via the transforming growth factor-beta signaling pathway in a mouse model of breast cancer.

Guillory B, Sakwe AM, Saria M, Thompson P, Adhiambo C, Koumangoye R, Ballard B, Binhazim A, Cone C, Jahanen-Dechent W, Ochieng J.

Am J Pathol. 2010 Nov;177(5):2635-44. doi: 10.2353/ajpath.2010.100177. Epub 2010 Sep 16.


Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.

Ochieng J, Pratap S, Khatua AK, Sakwe AM.

Exp Cell Res. 2009 Jul 1;315(11):1875-88. doi: 10.1016/j.yexcr.2009.03.010. Epub 2009 Mar 24.


Expression, crystallization and preliminary crystallographic data analysis of filamin A repeats 14-16.

Aguda AH, Sakwe AM, Rask L, Robinson RC.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt 4):291-3. Epub 2007 Mar 12.


Identification and characterization of a novel component of the human minichromosome maintenance complex.

Sakwe AM, Nguyen T, Athanasopoulos V, Shire K, Frappier L.

Mol Cell Biol. 2007 Apr;27(8):3044-55. Epub 2007 Feb 12.


Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins.

Larsson M, Hjälm G, Sakwe AM, Engström A, Höglund AS, Larsson E, Robinson RC, Sundberg C, Rask L.

Biochem J. 2003 Jul 15;373(Pt 2):381-91.


Biosynthesis and secretion of parathyroid hormone are sensitive to proteasome inhibitors in dispersed bovine parathyroid cells.

Sakwe AM, Engström A, Larsson M, Rask L.

J Biol Chem. 2002 May 17;277(20):17687-95. Epub 2002 Mar 7.


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