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Items: 21

1.

The mouse HP1 proteins are essential for preventing liver tumorigenesis.

Saksouk N, Hajdari S, Perez Y, Pratlong M, Barrachina C, Graber C, Grégoire D, Zavoriti A, Sarrazin A, Pirot N, Noël JY, Khellaf L, Fabbrizio E, Julien E, Cammas FM.

Oncogene. 2020 Feb 4. doi: 10.1038/s41388-020-1177-8. [Epub ahead of print]

PMID:
32020053
2.

SETDB1-dependent heterochromatin stimulates alternative lengthening of telomeres.

Gauchier M, Kan S, Barral A, Sauzet S, Agirre E, Bonnell E, Saksouk N, Barth TK, Ide S, Urbach S, Wellinger RJ, Luco RF, Imhof A, Déjardin J.

Sci Adv. 2019 May 8;5(5):eaav3673. doi: 10.1126/sciadv.aav3673. eCollection 2019 May.

3.

Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency.

van Mierlo G, Dirks RAM, De Clerck L, Brinkman AB, Huth M, Kloet SL, Saksouk N, Kroeze LI, Willems S, Farlik M, Bock C, Jansen JH, Deforce D, Vermeulen M, Déjardin J, Dhaenens M, Marks H.

Cell Stem Cell. 2019 Jan 3;24(1):123-137.e8. doi: 10.1016/j.stem.2018.10.017. Epub 2018 Nov 21.

4.

Proteome Characterization of a Chromatin Locus Using the Proteomics of Isolated Chromatin Segments Approach.

Kan SL, Saksouk N, Déjardin J.

Methods Mol Biol. 2017;1550:19-33. doi: 10.1007/978-1-4939-6747-6_3.

PMID:
28188520
5.

Constitutive heterochromatin formation and transcription in mammals.

Saksouk N, Simboeck E, Déjardin J.

Epigenetics Chromatin. 2015 Jan 15;8:3. doi: 10.1186/1756-8935-8-3. eCollection 2015. Review.

6.

Redundant mechanisms to form silent chromatin at pericentromeric regions rely on BEND3 and DNA methylation.

Saksouk N, Barth TK, Ziegler-Birling C, Olova N, Nowak A, Rey E, Mateos-Langerak J, Urbach S, Reik W, Torres-Padilla ME, Imhof A, Déjardin J, Simboeck E.

Mol Cell. 2014 Nov 20;56(4):580-94. doi: 10.1016/j.molcel.2014.10.001. Epub 2014 Nov 6. Erratum in: Mol Cell. 2015 Jan 8;57(1):202. Simboeck, Elisabeth [Added].

7.

Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity.

Lalonde ME, Avvakumov N, Glass KC, Joncas FH, Saksouk N, Holliday M, Paquet E, Yan K, Tong Q, Klein BJ, Tan S, Yang XJ, Kutateladze TG, Côté J.

Genes Dev. 2013 Sep 15;27(18):2009-24. doi: 10.1101/gad.223396.113.

8.

Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferation.

Avvakumov N, Lalonde ME, Saksouk N, Paquet E, Glass KC, Landry AJ, Doyon Y, Cayrou C, Robitaille GA, Richard DE, Yang XJ, Kutateladze TG, Côté J.

Mol Cell Biol. 2012 Feb;32(3):689-703. doi: 10.1128/MCB.06455-11. Epub 2011 Dec 5.

9.

Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension.

Paulin R, Courboulin A, Meloche J, Mainguy V, Dumas de la Roque E, Saksouk N, Côté J, Provencher S, Sussman MA, Bonnet S.

Circulation. 2011 Mar 22;123(11):1205-15. doi: 10.1161/CIRCULATIONAHA.110.963314. Epub 2011 Mar 7.

10.

Role for miR-204 in human pulmonary arterial hypertension.

Courboulin A, Paulin R, Giguère NJ, Saksouk N, Perreault T, Meloche J, Paquet ER, Biardel S, Provencher S, Côté J, Simard MJ, Bonnet S.

J Exp Med. 2011 Mar 14;208(3):535-48. doi: 10.1084/jem.20101812. Epub 2011 Feb 14.

11.

A Toxoplasma type 2C serine-threonine phosphatase is involved in parasite growth in the mammalian host cell.

Jan G, Delorme V, Saksouk N, Abrivard M, Gonzalez V, Cayla X, Hakimi MA, Tardieux I.

Microbes Infect. 2009 Oct;11(12):935-45. doi: 10.1016/j.micinf.2009.06.002. Epub 2009 Jun 27.

PMID:
19563907
12.

HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail.

Saksouk N, Avvakumov N, Champagne KS, Hung T, Doyon Y, Cayrou C, Paquet E, Ullah M, Landry AJ, Côté V, Yang XJ, Gozani O, Kutateladze TG, Côté J.

Mol Cell. 2009 Jan 30;33(2):257-65. doi: 10.1016/j.molcel.2009.01.007.

13.

Histone H3 tail clipping regulates gene expression.

Santos-Rosa H, Kirmizis A, Nelson C, Bartke T, Saksouk N, Cote J, Kouzarides T.

Nat Struct Mol Biol. 2009 Jan;16(1):17-22. doi: 10.1038/nsmb.1534. Epub 2008 Dec 14.

14.

The histone methylase KMTox interacts with the redox-sensor peroxiredoxin-1 and targets genes involved in Toxoplasma gondii antioxidant defences.

Sautel CF, Ortet P, Saksouk N, Kieffer S, Garin J, Bastien O, Hakimi MA.

Mol Microbiol. 2009 Jan;71(1):212-26. doi: 10.1111/j.1365-2958.2008.06519.x. Epub 2008 Nov 5.

15.

Role of Jade-1 in the histone acetyltransferase (HAT) HBO1 complex.

Foy RL, Song IY, Chitalia VC, Cohen HT, Saksouk N, Cayrou C, Vaziri C, Côté J, Panchenko MV.

J Biol Chem. 2008 Oct 24;283(43):28817-26. doi: 10.1074/jbc.M801407200. Epub 2008 Aug 6.

16.

The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide.

Champagne KS, Saksouk N, Peña PV, Johnson K, Ullah M, Yang XJ, Côté J, Kutateladze TG.

Proteins. 2008 Sep;72(4):1371-6. doi: 10.1002/prot.22140. No abstract available.

17.

(de)MYSTification and INGenuity of tumor suppressors.

Saksouk N, Avvakumov N, Côté J.

Cell Mol Life Sci. 2008 Apr;65(7-8):1013-8. doi: 10.1007/s00018-008-7459-x. Review. No abstract available.

PMID:
18239855
18.

Histone modifications in response to DNA damage.

Altaf M, Saksouk N, Côté J.

Mutat Res. 2007 May 1;618(1-2):81-90. Epub 2007 Jan 21. Review.

PMID:
17306843
19.

Histone-modifying complexes regulate gene expression pertinent to the differentiation of the protozoan parasite Toxoplasma gondii.

Saksouk N, Bhatti MM, Kieffer S, Smith AT, Musset K, Garin J, Sullivan WJ Jr, Cesbron-Delauw MF, Hakimi MA.

Mol Cell Biol. 2005 Dec;25(23):10301-14.

20.

The capsular polysaccharide biosynthesis of Streptococcus pneumoniae serotype 8: functional identification of the glycosyltransferase WciS (Cap8H).

Saksouk N, Pelosi L, Colin-Morel P, Boumedienne M, Abdian PL, Geremia RA.

Biochem J. 2005 Jul 1;389(Pt 1):63-72.

21.

The glucosyl-1-phosphate transferase WchA (Cap8E) primes the capsular polysaccharide repeat unit biosynthesis of Streptococcus pneumoniae serotype 8.

Pelosi L, Boumedienne M, Saksouk N, Geiselmann J, Geremia RA.

Biochem Biophys Res Commun. 2005 Feb 18;327(3):857-65.

PMID:
15649424

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