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Items: 17

1.

Haematopoietic stem cells in perisinusoidal niches are protected from ageing.

Saçma M, Pospiech J, Bogeska R, de Back W, Mallm JP, Sakk V, Soller K, Marka G, Vollmer A, Karns R, Cabezas-Wallscheid N, Trumpp A, Méndez-Ferrer S, Milsom MD, Mulaw MA, Geiger H, Florian MC.

Nat Cell Biol. 2019 Nov;21(11):1309-1320. doi: 10.1038/s41556-019-0418-y. Epub 2019 Nov 4.

PMID:
31685996
2.

HPRT and Purine Salvaging Are Critical for Hematopoietic Stem Cell Function.

Vogel M, Moehrle B, Brown A, Eiwen K, Sakk V, Geiger H.

Stem Cells. 2019 Dec;37(12):1606-1614. doi: 10.1002/stem.3087. Epub 2019 Oct 12.

PMID:
31574190
3.

The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function.

Brown A, Schuetz D, Han Y, Daria D, Nattamai KJ, Eiwen K, Sakk V, Pospiech J, Saller T, van Zant G, Wagner W, Geiger H.

Haematologica. 2020 Jan 31;105(2):317-324. doi: 10.3324/haematol.2018.213009. Print 2020. No abstract available.

4.

Aging alters the epigenetic asymmetry of HSC division.

Florian MC, Klose M, Sacma M, Jablanovic J, Knudson L, Nattamai KJ, Marka G, Vollmer A, Soller K, Sakk V, Cabezas-Wallscheid N, Zheng Y, Mulaw MA, Glauche I, Geiger H.

PLoS Biol. 2018 Sep 20;16(9):e2003389. doi: 10.1371/journal.pbio.2003389. eCollection 2018 Sep.

5.

Epigenetic age-predictor for mice based on three CpG sites.

Han Y, Eipel M, Franzen J, Sakk V, Dethmers-Ausema B, Yndriago L, Izeta A, de Haan G, Geiger H, Wagner W.

Elife. 2018 Aug 24;7. pii: e37462. doi: 10.7554/eLife.37462.

6.

Aged murine hematopoietic stem cells drive aging-associated immune remodeling.

Leins H, Mulaw M, Eiwen K, Sakk V, Liang Y, Denkinger M, Geiger H, Schirmbeck R.

Blood. 2018 Aug 9;132(6):565-576. doi: 10.1182/blood-2018-02-831065. Epub 2018 Jun 11.

7.

The Spindle Assembly Checkpoint Is Required for Hematopoietic Progenitor Cell Engraftment.

Brown A, Pospiech J, Eiwen K, Baker DJ, Moehrle B, Sakk V, Nattamai K, Vogel M, Grigoryan A, Geiger H.

Stem Cell Reports. 2017 Nov 14;9(5):1359-1368. doi: 10.1016/j.stemcr.2017.09.017. Epub 2017 Oct 19.

8.

Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.

Tao S, Tang D, Morita Y, Sperka T, Omrani O, Lechel A, Sakk V, Kraus J, Kestler HA, Kühl M, Rudolph KL.

EMBO J. 2017 Oct 2;36(19):2920-2921. doi: 10.15252/embj.201797813. No abstract available.

9.

Septin 6 regulates engraftment and lymphoid differentiation potential of murine long-term hematopoietic stem cells.

Senger K, Marka G, Soller K, Sakk V, Florian MC, Geiger H.

Exp Hematol. 2017 Nov;55:45-55. doi: 10.1016/j.exphem.2017.07.005. Epub 2017 Jul 24.

PMID:
28751190
10.

Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.

Tao S, Tang D, Morita Y, Sperka T, Omrani O, Lechel A, Sakk V, Kraus J, Kestler HA, Kühl M, Rudolph KL.

EMBO J. 2015 Mar 4;34(5):624-40. doi: 10.15252/embj.201490700. Epub 2015 Jan 21. Erratum in: EMBO J. 2017 Oct 2;36(19):2920-2921.

11.

Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres.

Wang J, Lu X, Sakk V, Klein CA, Rudolph KL.

Blood. 2014 Nov 20;124(22):3237-40. doi: 10.1182/blood-2014-04-568055. Epub 2014 Sep 16.

12.

The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation.

Sirma H, Kumar M, Meena JK, Witt B, Weise JM, Lechel A, Ande S, Sakk V, Guguen-Guillouzo C, Zender L, Rudolph KL, Günes C.

Gastroenterology. 2011 Jul;141(1):326-37, 337.e1-3. doi: 10.1053/j.gastro.2011.03.047. Epub 2011 Mar 27.

PMID:
21447332
13.

AlphaPIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling.

Missy K, Hu B, Schilling K, Harenberg A, Sakk V, Kuchenbecker K, Kutsche K, Fischer KD.

Mol Cell Biol. 2008 Jun;28(11):3776-89. doi: 10.1128/MCB.00507-07. Epub 2008 Mar 31.

14.
15.

The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization.

Girkontaite I, Sakk V, Wagner M, Borggrefe T, Tedford K, Chun J, Fischer KD.

J Exp Med. 2004 Dec 6;200(11):1491-501.

16.

Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses.

Girkontaite I, Missy K, Sakk V, Harenberg A, Tedford K, Pötzel T, Pfeffer K, Fischer KD.

Nat Immunol. 2001 Sep;2(9):855-62.

PMID:
11526402
17.

Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling.

Tedford K, Nitschke L, Girkontaite I, Charlesworth A, Chan G, Sakk V, Barbacid M, Fischer KD.

Nat Immunol. 2001 Jun;2(6):548-55.

PMID:
11376343

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