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Items: 1 to 50 of 319

1.

Endocannabinoid Signaling from 2-Arachidonoylglycerol to CB1 Cannabinoid Receptor Facilitates Reward-based Learning of Motor Sequence.

Tanigami H, Yoneda M, Tabata Y, Echigo R, Kikuchi Y, Yamazaki M, Kishimoto Y, Sakimura K, Kano M, Ohno-Shosaku T.

Neuroscience. 2019 Nov 1;421:1-16. doi: 10.1016/j.neuroscience.2019.09.040. [Epub ahead of print]

PMID:
31682822
2.

Expression mapping, quantification, and complex formation of GluD1 and GluD2 glutamate receptors in adult mouse brain.

Nakamoto C, Konno K, Miyazaki T, Nakatsukasa E, Natsume R, Abe M, Kawamura M, Fukazawa Y, Shigemto R, Yamasaki M, Sakimura K, Watanabe M.

J Comp Neurol. 2019 Oct 18. doi: 10.1002/cne.24792. [Epub ahead of print]

PMID:
31625608
3.

Modular organization of cerebellar climbing fiber inputs during goal-directed behavior.

Tsutsumi S, Hidaka N, Isomura Y, Matsuzaki M, Sakimura K, Kano M, Kitamura K.

Elife. 2019 Oct 9;8. pii: e47021. doi: 10.7554/eLife.47021.

4.

Differential Roles of Each Orexin Receptor Signaling in Obesity.

Kakizaki M, Tsuneoka Y, Takase K, Kim SJ, Choi J, Ikkyu A, Abe M, Sakimura K, Yanagisawa M, Funato H.

iScience. 2019 Oct 25;20:1-13. doi: 10.1016/j.isci.2019.09.003. Epub 2019 Sep 9.

5.

Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1-Akt signaling pathway.

Nishino K, Watanabe S, Shijie J, Murata Y, Oiwa K, Komine O, Endo F, Tsuiji H, Abe M, Sakimura K, Mishra A, Yamanaka K.

Acta Neuropathol Commun. 2019 Jul 25;7(1):118. doi: 10.1186/s40478-019-0776-5.

6.

Monoacylglycerol lipase blockade impairs fine motor coordination and triggers cerebellar neuroinflammation through cyclooxygenase-2.

Martínez-Torres S, Cutando L, Pastor A, Kato A, Sakimura K, de la Torre R, Valjent E, Maldonado R, Kano M, Ozaita A.

Brain Behav Immun. 2019 Oct;81:399-409. doi: 10.1016/j.bbi.2019.06.036. Epub 2019 Jun 25.

PMID:
31251974
7.

Non-coding cis-element of Period2 is essential for maintaining organismal circadian behaviour and body temperature rhythmicity.

Doi M, Shimatani H, Atobe Y, Murai I, Hayashi H, Takahashi Y, Fustin JM, Yamaguchi Y, Kiyonari H, Koike N, Yagita K, Lee C, Abe M, Sakimura K, Okamura H.

Nat Commun. 2019 Jun 12;10(1):2563. doi: 10.1038/s41467-019-10532-2.

8.

GABA neurons in the ventral tegmental area regulate non-rapid eye movement sleep in mice.

Chowdhury S, Matsubara T, Miyazaki T, Ono D, Fukatsu N, Abe M, Sakimura K, Sudo Y, Yamanaka A.

Elife. 2019 Jun 4;8. pii: e44928. doi: 10.7554/eLife.44928.

9.

Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice.

Chowdhury S, Hung CJ, Izawa S, Inutsuka A, Kawamura M, Kawashima T, Bito H, Imayoshi I, Abe M, Sakimura K, Yamanaka A.

Elife. 2019 Jun 4;8. pii: e44927. doi: 10.7554/eLife.44927.

10.

Cerebellar Neurodegeneration and Neuronal Circuit Remodeling in Golgi pH Regulator-Deficient Mice.

Sou YS, Kakuta S, Kamikubo Y, Niisato K, Sakurai T, Parajuli LK, Tanida I, Saito H, Suzuki N, Sakimura K, Maeda Y, Kinoshita T, Uchiyama Y, Koike M.

eNeuro. 2019 May 29;6(3). pii: ENEURO.0427-18.2019. doi: 10.1523/ENEURO.0427-18.2019. Print 2019 May/Jun.

11.

Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics.

Inoue M, Takeuchi A, Manita S, Horigane SI, Sakamoto M, Kawakami R, Yamaguchi K, Otomo K, Yokoyama H, Kim R, Yokoyama T, Takemoto-Kimura S, Abe M, Okamura M, Kondo Y, Quirin S, Ramakrishnan C, Imamura T, Sakimura K, Nemoto T, Kano M, Fujii H, Deisseroth K, Kitamura K, Bito H.

Cell. 2019 May 16;177(5):1346-1360.e24. doi: 10.1016/j.cell.2019.04.007. Epub 2019 May 9.

PMID:
31080068
12.

Impaired cortico-striatal excitatory transmission triggers epilepsy.

Miyamoto H, Tatsukawa T, Shimohata A, Yamagata T, Suzuki T, Amano K, Mazaki E, Raveau M, Ogiwara I, Oba-Asaka A, Hensch TK, Itohara S, Sakimura K, Kobayashi K, Kobayashi K, Yamakawa K.

Nat Commun. 2019 Apr 23;10(1):1917. doi: 10.1038/s41467-019-09954-9.

13.

Correction to: Female-biased sexual dimorphism of corticotropin-releasing factor neurons in the bed nucleus of the stria terminalis.

Uchida K, Otsuka H, Morishita M, Tsukahara S, Sato T, Sakimura K, Itoi K.

Biol Sex Differ. 2019 Feb 19;10(1):10. doi: 10.1186/s13293-019-0224-z.

14.

Glutamatergic neurons in the medial prefrontal cortex mediate the formation and retrieval of cocaine-associated memories in mice.

Zhang T, Yanagida J, Kamii H, Wada S, Domoto M, Sasase H, Deyama S, Takarada T, Hinoi E, Sakimura K, Yamanaka A, Maejima T, Mieda M, Sakurai T, Nishitani N, Nagayasu K, Kaneko S, Minami M, Kaneda K.

Addict Biol. 2019 Feb 7. doi: 10.1111/adb.12723. [Epub ahead of print]

PMID:
30734456
15.

ELKS/Voltage-Dependent Ca2+ Channel-β Subunit Module Regulates Polarized Ca2+ Influx in Pancreatic β Cells.

Ohara-Imaizumi M, Aoyagi K, Yamauchi H, Yoshida M, Mori MX, Hida Y, Tran HN, Ohkura M, Abe M, Akimoto Y, Nakamichi Y, Nishiwaki C, Kawakami H, Hara K, Sakimura K, Nagamatsu S, Mori Y, Nakai J, Kakei M, Ohtsuka T.

Cell Rep. 2019 Jan 29;26(5):1213-1226.e7. doi: 10.1016/j.celrep.2018.12.106.

16.

Female-biased sexual dimorphism of corticotropin-releasing factor neurons in the bed nucleus of the stria terminalis.

Uchida K, Otsuka H, Morishita M, Tsukahara S, Sato T, Sakimura K, Itoi K.

Biol Sex Differ. 2019 Jan 28;10(1):6. doi: 10.1186/s13293-019-0221-2. Erratum in: Biol Sex Differ. 2019 Feb 19;10(1):10.

17.

Correction: T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice.

Wang S, Yabuki Y, Matsuo K, Xu J, Izumi H, Sakimura K, Saito T, Saido TC, Fukunaga K.

PLoS One. 2019 Jan 25;14(1):e0211590. doi: 10.1371/journal.pone.0211590. eCollection 2019.

18.

Mechanical regulation of oligodendrocyte morphology and maturation by the mechanosensor p130Cas.

Shimizu T, Osanai Y, Tanaka KF, Thai TQ, Abe M, Natsume R, Sakimura K, Ikenaka K.

J Neurochem. 2019 Jul;150(2):158-172. doi: 10.1111/jnc.14657. Epub 2019 Jan 29.

PMID:
30589943
19.

T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice.

Wang S, Yabuki Y, Matsuo K, Xu J, Izumi H, Sakimura K, Saito T, Saido TC, Fukunaga K.

PLoS One. 2018 Dec 20;13(12):e0206986. doi: 10.1371/journal.pone.0206986. eCollection 2018. Erratum in: PLoS One. 2019 Jan 25;14(1):e0211590.

20.

Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture.

Saito YC, Tsujino N, Abe M, Yamazaki M, Sakimura K, Sakurai T.

Front Neurosci. 2018 Nov 30;12:892. doi: 10.3389/fnins.2018.00892. eCollection 2018.

21.

Perturbed expression pattern of the immediate early gene Arc in the dentate gyrus of GluA1 C-terminal palmitoylation-deficient mice.

Itoh M, Okuno H, Yamada D, Yamashita M, Abe M, Natsume R, Kaizuka T, Sakimura K, Hoshino M, Mishina M, Wada K, Sekiguchi M, Hayashi T.

Neuropsychopharmacol Rep. 2019 Mar;39(1):61-66. doi: 10.1002/npr2.12044. Epub 2018 Dec 7.

22.

Autophosphorylation of F-actin binding domain of CaMKIIβ is required for fear learning.

Kim K, Suzuki A, Kojima H, Kawamura M, Miya K, Abe M, Yamada I, Furuse T, Wakana S, Sakimura K, Hayashi Y.

Neurobiol Learn Mem. 2019 Jan;157:86-95. doi: 10.1016/j.nlm.2018.12.003. Epub 2018 Dec 7.

PMID:
30528771
23.

Different Roles of Sphingosine Kinase 1 and 2 in Pancreatic Cancer Progression.

Yuza K, Nakajima M, Nagahashi M, Tsuchida J, Hirose Y, Miura K, Tajima Y, Abe M, Sakimura K, Takabe K, Wakai T.

J Surg Res. 2018 Dec;232:186-194. doi: 10.1016/j.jss.2018.06.019. Epub 2018 Jul 6.

PMID:
30463717
24.

Distribution of Caskin1 protein and phenotypic characterization of its knockout mice using a comprehensive behavioral test battery.

Katano T, Takao K, Abe M, Yamazaki M, Watanabe M, Miyakawa T, Sakimura K, Ito S.

Mol Brain. 2018 Oct 25;11(1):63. doi: 10.1186/s13041-018-0407-2.

25.

Deficiency of AMPAR-Palmitoylation Aggravates Seizure Susceptibility.

Itoh M, Yamashita M, Kaneko M, Okuno H, Abe M, Yamazaki M, Natsume R, Yamada D, Kaizuka T, Suwa R, Sakimura K, Sekiguchi M, Wada K, Hoshino M, Mishina M, Hayashi T.

J Neurosci. 2018 Nov 21;38(47):10220-10235. doi: 10.1523/JNEUROSCI.1590-18.2018. Epub 2018 Oct 24.

26.

NMDA receptors mediate synaptic depression, but not spine loss in the dentate gyrus of adult amyloid Beta (Aβ) overexpressing mice.

Müller MK, Jacobi E, Sakimura K, Malinow R, von Engelhardt J.

Acta Neuropathol Commun. 2018 Oct 23;6(1):110. doi: 10.1186/s40478-018-0611-4.

27.

Drebrin Isoforms Critically Regulate NMDAR- and mGluR-Dependent LTD Induction.

Yasuda H, Kojima N, Hanamura K, Yamazaki H, Sakimura K, Shirao T.

Front Cell Neurosci. 2018 Oct 8;12:330. doi: 10.3389/fncel.2018.00330. eCollection 2018.

28.

Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion.

Sakimura K, Maekawa T, Kume SI, Ohta T.

Int J Endocrinol. 2018 Sep 23;2018:9065690. doi: 10.1155/2018/9065690. eCollection 2018.

29.

Monoacylglycerol lipase deficiency affects diet-induced obesity, fat absorption, and feeding behavior in CB1 cannabinoid receptor-deficient mice.

Yoshida K, Kita Y, Tokuoka SM, Hamano F, Yamazaki M, Sakimura K, Kano M, Shimizu T.

FASEB J. 2019 Feb;33(2):2484-2497. doi: 10.1096/fj.201801203R. Epub 2018 Sep 28.

PMID:
30265576
30.

The role of sphingosine-1-phosphate in inflammation and cancer progression.

Nagahashi M, Abe M, Sakimura K, Takabe K, Wakai T.

Cancer Sci. 2018 Dec;109(12):3671-3678. doi: 10.1111/cas.13802. Epub 2018 Oct 15. Review.

31.

Deletion of exons encoding carboxypeptidase domain of Nna1 results in Purkinje cell degeneration (pcd) phenotype.

Zhou L, Hossain MI, Yamazaki M, Abe M, Natsume R, Konno K, Kageyama S, Komatsu M, Watanabe M, Sakimura K, Takebayashi H.

J Neurochem. 2018 Nov;147(4):557-572. doi: 10.1111/jnc.14591. Epub 2018 Nov 6.

32.

Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance.

Hagiwara A, Kitahara Y, Grabner CP, Vogl C, Abe M, Kitta R, Ohta K, Nakamura K, Sakimura K, Moser T, Nishi A, Ohtsuka T.

J Cell Biol. 2018 Nov 5;217(11):3993-4006. doi: 10.1083/jcb.201704076. Epub 2018 Sep 6.

33.

Cathepsin C modulates myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.

Durose WW, Shimizu T, Li J, Abe M, Sakimura K, Chetsawang B, Tanaka KF, Suzumura A, Tohyama K, Ikenaka K.

J Neurochem. 2019 Feb;148(3):413-425. doi: 10.1111/jnc.14581. Epub 2018 Dec 3.

PMID:
30152001
34.

A glycine transporter 2-Cre knock-in mouse line for glycinergic neuron-specific gene manipulation.

Kakizaki T, Sakagami H, Sakimura K, Yanagawa Y.

IBRO Rep. 2017 Aug 8;3:9-16. doi: 10.1016/j.ibror.2017.07.002. eCollection 2017 Dec.

35.

Ablation of Central Serotonergic Neurons Decreased REM Sleep and Attenuated Arousal Response.

Iwasaki K, Komiya H, Kakizaki M, Miyoshi C, Abe M, Sakimura K, Funato H, Yanagisawa M.

Front Neurosci. 2018 Aug 7;12:535. doi: 10.3389/fnins.2018.00535. eCollection 2018.

36.

Eukaryotic translation initiation factor 3 (eIF3) subunit e is essential for embryonic development and cell proliferation.

Sadato D, Ono T, Gotoh-Saito S, Kajiwara N, Nomura N, Ukaji M, Yang L, Sakimura K, Tajima Y, Oboki K, Shibasaki F.

FEBS Open Bio. 2018 Jul 5;8(8):1188-1201. doi: 10.1002/2211-5463.12482. eCollection 2018 Aug.

37.

Higher visual responses in the temporal cortex of mice.

Nishio N, Tsukano H, Hishida R, Abe M, Nakai J, Kawamura M, Aiba A, Sakimura K, Shibuki K.

Sci Rep. 2018 Jul 24;8(1):11136. doi: 10.1038/s41598-018-29530-3.

38.

Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum.

Nakayama H, Abe M, Morimoto C, Iida T, Okabe S, Sakimura K, Hashimoto K.

Nat Commun. 2018 Jul 19;9(1):2830. doi: 10.1038/s41467-018-05100-z.

39.

CAST/ELKS Proteins Control Voltage-Gated Ca2+ Channel Density and Synaptic Release Probability at a Mammalian Central Synapse.

Dong W, Radulovic T, Goral RO, Thomas C, Suarez Montesinos M, Guerrero-Given D, Hagiwara A, Putzke T, Hida Y, Abe M, Sakimura K, Kamasawa N, Ohtsuka T, Young SM Jr.

Cell Rep. 2018 Jul 10;24(2):284-293.e6. doi: 10.1016/j.celrep.2018.06.024.

40.

MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells.

Kawabata Galbraith K, Fujishima K, Mizuno H, Lee SJ, Uemura T, Sakimura K, Mishina M, Watanabe N, Kengaku M.

Cell Rep. 2018 Jul 3;24(1):95-106.e9. doi: 10.1016/j.celrep.2018.06.013.

41.

Depression-related behavioural and neuroendocrine changes in the Spontaneously Diabetic Torii (SDT) fatty rat, an animal model of type 2 diabetes mellitus.

Sakimura K, Maekawa T, Sasagawa K, Ishii Y, Kume SI, Ohta T.

Clin Exp Pharmacol Physiol. 2018 May 14. doi: 10.1111/1440-1681.12965. [Epub ahead of print]

PMID:
29757463
42.

Keratan Sulfate Phenotype in the β-1,3-N-Acetylglucosaminyltransferase-7-Null Mouse Cornea.

Littlechild SL, Young RD, Caterson B, Yoshida H, Yamazaki M, Sakimura K, Quantock AJ, Akama TO.

Invest Ophthalmol Vis Sci. 2018 Mar 1;59(3):1641-1651. doi: 10.1167/iovs.17-22716.

43.

Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum.

Uesaka N, Abe M, Konno K, Yamazaki M, Sakoori K, Watanabe T, Kao TH, Mikuni T, Watanabe M, Sakimura K, Kano M.

Neuron. 2018 Feb 21;97(4):796-805.e5. doi: 10.1016/j.neuron.2018.01.018. Epub 2018 Feb 1.

44.

Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis.

Nagahashi M, Yamada A, Katsuta E, Aoyagi T, Huang WC, Terracina KP, Hait NC, Allegood JC, Tsuchida J, Yuza K, Nakajima M, Abe M, Sakimura K, Milstien S, Wakai T, Spiegel S, Takabe K.

Cancer Res. 2018 Apr 1;78(7):1713-1725. doi: 10.1158/0008-5472.CAN-17-1423. Epub 2018 Jan 19.

45.

Input-Specific NMDAR-Dependent Potentiation of Dendritic GABAergic Inhibition.

Chiu CQ, Martenson JS, Yamazaki M, Natsume R, Sakimura K, Tomita S, Tavalin SJ, Higley MJ.

Neuron. 2018 Jan 17;97(2):368-377.e3. doi: 10.1016/j.neuron.2017.12.032.

46.

CDC42EP4, a perisynaptic scaffold protein in Bergmann glia, is required for glutamatergic tripartite synapse configuration.

Ageta-Ishihara N, Konno K, Yamazaki M, Abe M, Sakimura K, Watanabe M, Kinoshita M.

Neurochem Int. 2018 Oct;119:190-198. doi: 10.1016/j.neuint.2018.01.003. Epub 2018 Jan 9.

PMID:
29330091
47.

Corrigendum: Conditional Knockout of Cav2.1 Disrupts the Accuracy of Spatial Recognition of CA1 Place Cells and Spatial/Contextual Recognition Behavior.

Jung D, Hwang YJ, Ryu H, Kano M, Sakimura K, Cho J.

Front Behav Neurosci. 2017 Dec 8;11:242. doi: 10.3389/fnbeh.2017.00242. eCollection 2017.

48.

Maturation of Cerebellar Purkinje Cell Population Activity during Postnatal Refinement of Climbing Fiber Network.

Good JM, Mahoney M, Miyazaki T, Tanaka KF, Sakimura K, Watanabe M, Kitamura K, Kano M.

Cell Rep. 2017 Nov 21;21(8):2066-2073. doi: 10.1016/j.celrep.2017.10.101.

49.

Protocadherin-αC2 is required for diffuse projections of serotonergic axons.

Katori S, Noguchi-Katori Y, Okayama A, Kawamura Y, Luo W, Sakimura K, Hirabayashi T, Iwasato T, Yagi T.

Sci Rep. 2017 Nov 21;7(1):15908. doi: 10.1038/s41598-017-16120-y.

50.

RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation.

Nakayama K, Ohashi R, Shinoda Y, Yamazaki M, Abe M, Fujikawa A, Shigenobu S, Futatsugi A, Noda M, Mikoshiba K, Furuichi T, Sakimura K, Shiina N.

Elife. 2017 Nov 21;6. pii: e29677. doi: 10.7554/eLife.29677.

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