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H2 FPEF score for predicting future heart failure in stable outpatients with cardiovascular risk factors.

Suzuki S, Kaikita K, Yamamoto E, Sueta D, Yamamoto M, Ishii M, Ito M, Fujisue K, Kanazawa H, Araki S, Arima Y, Takashio S, Usuku H, Nakamura T, Sakamoto K, Izumiya Y, Soejima H, Kawano H, Jinnouchi H, Matsui K, Tsujita K.

ESC Heart Fail. 2020 Jan 22. doi: 10.1002/ehf2.12570. [Epub ahead of print]


A Progressive Huge Accessory Spleen in the Greater Omentum.

Matsuzawa H, Munakata S, Momose H, Tsuchiya Y, Ishiyama S, Kamiyama H, Takahashi M, Sakamoto K.

Case Rep Gastroenterol. 2019 Dec 19;13(3):539-543. doi: 10.1159/000504433. eCollection 2019 Sep-Dec.


A Phase 1, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Subcutaneous Tezepelumab in Healthy Japanese Men.

Sakamoto K, Matsuki S, Irie S, Uchida N, Hayashi N, Horiuchi M, Ren S.

Clin Pharmacol Drug Dev. 2020 Jan 20. doi: 10.1002/cpdd.775. [Epub ahead of print]


Targeted therapy guided by single-cell transcriptomic analysis in drug-induced hypersensitivity syndrome: a case report.

Kim D, Kobayashi T, Voisin B, Jo JH, Sakamoto K, Jin SP, Kelly M, Pasieka HB, Naff JL, Meyerle JH, Ikpeama ID, Fahle GA, Davis FP, Rosenzweig SD, Alejo JC, Pittaluga S, Kong HH, Freeman AF, Nagao K.

Nat Med. 2020 Jan 20. doi: 10.1038/s41591-019-0733-7. [Epub ahead of print]


TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice.

Ono Y, Maejima Y, Saito M, Sakamoto K, Horita S, Shimomura K, Inoue S, Kotani J.

Sci Rep. 2020 Jan 20;10(1):694. doi: 10.1038/s41598-020-57714-3.


Three different CT and FGD PET/CT findings of pulmonary involvement in methotrexate-associated lymphoproliferative disease.

Matsubayashi S, Suzuki M, Sakamoto K, Izumi S, Hojo M, Sugiyama H.

Respirol Case Rep. 2020 Jan 14;8(2):e00520. doi: 10.1002/rcr2.520. eCollection 2020 Mar.


Short-term exposure to desert dust and the risk of acute myocardial infarction in Japan: a time-stratified case-crossover study.

Ishii M, Seki T, Kaikita K, Sakamoto K, Nakai M, Sumita Y, Nishimura K, Miyamoto Y, Noguchi T, Yasuda S, Tsutsui H, Komuro I, Saito Y, Ogawa H, Tsujita K, Kawakami K; JROAD Investigators.

Eur J Epidemiol. 2020 Jan 16. doi: 10.1007/s10654-020-00601-y. [Epub ahead of print]


Efficient tissue-type specific expression of target genes in a tetracycline-controlled manner from the ubiquitously active Eef1a1 locus.

Sakamoto K, Rädler PD, Wehde BL, Triplett AA, Shrestha H, Ferraiuolo RM, Amari F, Coppola V, Klinakis A, Efstratiadis A, Wagner KU.

Sci Rep. 2020 Jan 14;10(1):207. doi: 10.1038/s41598-019-57052-z.


Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer.

Takahashi R, Sakamoto K, Sugimoto K, Motegi S, Tsukamoto R, Ichikawa R, Okazawa Y, Aoki J, Ishiyama S, Takahashi M, Kojima Y, Okuzawa A, Tomiki Y, Matsuoka J.

Dis Markers. 2019 Dec 14;2019:2721876. doi: 10.1155/2019/2721876. eCollection 2019.


Myofascia-dominant involvement on whole-body MRI as a risk factor for rapidly progressive interstitial lung disease in dermatomyositis.

Karino K, Kono M, Kono M, Sakamoto K, Fujieda Y, Kato M, Amengual O, Oku K, Yasuda S, Atsumi T.

Rheumatology (Oxford). 2020 Jan 10. pii: kez642. doi: 10.1093/rheumatology/kez642. [Epub ahead of print]


Differences in task-phase-dependent time-frequency patterns of local field potentials in the dorsal and ventral regions of the monkey lateral prefrontal cortex.

Sakamoto K, Kawaguchi N, Mushiake H.

Neurosci Res. 2020 Jan 7. pii: S0168-0102(19)30693-5. doi: 10.1016/j.neures.2019.12.016. [Epub ahead of print]


Neuropathology and diagnostic features of rabies in a litter of piglets, with a brief review of the literature.

Siepker CL, Dalton MF, McHale BJ, Sakamoto K, Rissi DR.

J Vet Diagn Invest. 2020 Jan 9:1040638719898687. doi: 10.1177/1040638719898687. [Epub ahead of print]


Effects of Receptor for Advanced Glycation End-Products (RAGE) Signaling on Intestinal Ischemic Damage in Mice.

Makino Y, Munakata S, Ueyama T, Honjo K, Kawano S, Takahashi M, Kojima Y, Tomiki Y, Sakamoto K.

Eur Surg Res. 2020 Jan 8:1-9. doi: 10.1159/000504751. [Epub ahead of print]



Huang M, Zeki J, Sumarsono N, Coles GL, Taylor JS, Danzer E, Bruzoni M, Hazard FK, Lacayo NJ, Sakamoto KM, Dunn JCY, Spunt SL, Chiu B.

Cancer Res. 2020 Jan 3. pii: canres.2560.2019. doi: 10.1158/0008-5472.CAN-19-2560. [Epub ahead of print]


Proposed grading scheme for inflammatory bowel disease in ferrets and correlation with clinical signs.

Cazzini P, Watson MK, Gottdenker N, Mayer J, Reavill D, Fox JG, Parry N, Sakamoto K.

J Vet Diagn Invest. 2019 Dec 30:1040638719896555. doi: 10.1177/1040638719896555. [Epub ahead of print]


Reply to "Prognostic Impact and Risk Factors of Immune-Related Pneumonitis in Patients With Non-Small-Cell Lung Cancer Who Received Programmed Death-1 Inhibitors".

Fukihara J, Sakamoto K, Koyama J, Ito T, Iwano S, Morise M, Ogawa M, Kondoh Y, Kimura T, Hashimoto N, Hasegawa Y.

Clin Lung Cancer. 2019 Dec 2. pii: S1525-7304(19)30330-4. doi: 10.1016/j.cllc.2019.11.013. [Epub ahead of print] No abstract available.


Prognostic significance of the controlling nutritional status (CONUT) score in advanced urothelial carcinoma patients.

Suzuki H, Ito M, Takemura K, Nakanishi Y, Kataoka M, Sakamoto K, Tobisu KI, Koga F.

Urol Oncol. 2019 Dec 18. pii: S1078-1439(19)30438-7. doi: 10.1016/j.urolonc.2019.10.014. [Epub ahead of print]


A Novel, Tumor-Induced Osteoclastogenesis Pathway Insensitive to Denosumab but Interfered by Cannabidiol.

Tsuchiya M, Kayamori K, Wada A, Komaki M, Ohata Y, Hamagaki M, Sakamoto K, Ikeda T.

Int J Mol Sci. 2019 Dec 9;20(24). pii: E6211. doi: 10.3390/ijms20246211.


Synthesis of (Z)-β-(carbonylamino)alkenylindium via Regioselective Anti-carboindation of Ynamides and Its Transformation to Multisubstituted Enamides.

Kang K, Sakamoto K, Nishimoto Y, Yasuda M.

Chemistry. 2019 Dec 13. doi: 10.1002/chem.201905175. [Epub ahead of print]


Changes in components of the neurovascular unit in the retina in a rat model of retinopathy of prematurity.

Nakano A, Kondo R, Kaneko Y, Arima S, Asano D, Morita A, Sakamoto K, Nagamitsu T, Nakahara T.

Cell Tissue Res. 2019 Dec 2. doi: 10.1007/s00441-019-03112-9. [Epub ahead of print]


Elongation of the high right atrium to coronary sinus conduction time predicts the recurrence of atrial fibrillation after radiofrequency catheter ablation.

Kanemaru Y, Arima Y, Kaikita K, Kiyama T, Kaneko S, Ito M, Yamabe H, Motozato K, Yamanaga K, Fujisue K, Sueta D, Takashio S, Araki S, Usuku H, Nakamura T, Fukunaga T, Suzuki S, Izumiya Y, Sakamoto K, Soejima H, Yamamoto E, Kawano H, Kanazawa H, Tsujita K.

Int J Cardiol. 2020 Feb 1;300:147-153. doi: 10.1016/j.ijcard.2019.10.044. Epub 2019 Nov 18.


Intracellular claudin-1 at the invasive front of tongue squamous cell carcinoma is associated with lymph node metastasis.

Yamamoto D, Kayamori K, Sakamoto K, Tsuchiya M, Ikeda T, Harada H, Yoda T, Watabe T, Hara-Yokoyama M.

Cancer Sci. 2019 Nov 26. doi: 10.1111/cas.14249. [Epub ahead of print]


Persistent Renal Dysfunction in Patients Undergoing Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction.

Kurogi K, Ishii M, Sakamoto K, Komaki S, Marume K, Kusaka H, Yamamoto N, Arima Y, Yamamoto E, Kaikita K, Tsujita K.

J Am Heart Assoc. 2019 Dec 3;8(23):e014096. doi: 10.1161/JAHA.119.014096. Epub 2019 Nov 26.


A case of repetitive acute coronary syndrome in a patient with familial hypercholesterolemia.

Motozato K, Sueta D, Sakamoto K, Nagamatsu S, Yamashita T, Sato R, Mitsuse T, Kanemaru Y, Takaoka K, Fujisue K, Takashio S, Arima Y, Yamamoto E, Kaikita K, Tsujita K.

J Cardiol Cases. 2019 Sep 14;20(6):200-204. doi: 10.1016/j.jccase.2019.08.007. eCollection 2019 Dec.


Co-expression of EGFR and MET has a synergistic effect on the prognosis of patients with oral squamous cell carcinoma.

Yokokawa M, Morita KI, Oikawa Y, Kayamori K, Sakamoto K, Ikeda T, Harada H.

J Oral Pathol Med. 2019 Nov 25. doi: 10.1111/jop.12977. [Epub ahead of print]


[A Case of Rapidly Progressing High-grade B-cell Lymphoma with <i>c-Myc</i> Translocation and Bcl-2 Protein Expression].

Morinaga Y, Nii K, Sakamoto K, Inoue R, Mitsutake T, Hanada H, Tsutsumi M.

No Shinkei Geka. 2019 Nov;47(11):1179-1184. doi: 10.11477/mf.1436204096. Japanese.


Novel mechanism of increasing cerebral vascular constriction in acute hyperglycemia and diabetes through adenylyl cyclase 5-generated cyclic adenosine monophosphate.

Sakamoto K, Yokote K.

J Diabetes Investig. 2019 Nov 23. doi: 10.1111/jdi.13186. [Epub ahead of print] No abstract available.


Characteristics and in-hospital mortality of patients with myocardial infarction in the absence of obstructive coronary artery disease in super-aging society.

Ishii M, Kaikita K, Sakamoto K, Seki T, Kawakami K, Nakai M, Sumita Y, Nishimura K, Miyamoto Y, Noguchi T, Yasuda S, Tsutsui H, Komuro I, Saito Y, Ogawa H, Tsujita K; JROAD Investigators.

Int J Cardiol. 2020 Feb 15;301:108-113. doi: 10.1016/j.ijcard.2019.09.037. Epub 2019 Oct 25.


Clinical Features of Patients with Acute Aortic Dissection After an Earthquake ~Experience from The Kumamoto Earthquake 2016~.

Komorita T, Fujisue K, Sueta D, Sakamoto K, Yamamoto E, Hashimoto Y, Sakamoto T, Tsunoda R, Uesugi H, Suzuki R, Naito H, Hanzawa K, Araki E, Nakayama H, Kasaoka S, Hokimoto S, Fukui T, Tsujita K.

Am J Hypertens. 2019 Nov 18. pii: hpz183. doi: 10.1093/ajh/hpz183. [Epub ahead of print]


Surgical resection for persistent localized pulmonary fungal infection prior to allogeneic hematopoietic stem cell transplantation: Analysis of six cases.

Harada N, Kimura SI, Gomyo A, Hayakawa J, Tamaki M, Akahoshi Y, Ugai T, Kusuda M, Kameda K, Wada H, Ishihara Y, Kawamura K, Sakamoto K, Sato M, Terasako-Saito K, Kikuchi M, Nakasone H, Kako S, Tsubochi H, Kanda Y.

J Infect Chemother. 2019 Nov 15. pii: S1341-321X(19)30237-5. doi: 10.1016/j.jiac.2019.08.003. [Epub ahead of print]


Cardiomyocyte Sirt (Sirtuin) 7 Ameliorates Stress-Induced Cardiac Hypertrophy by Interacting With and Deacetylating GATA4.

Yamamura S, Izumiya Y, Araki S, Nakamura T, Kimura Y, Hanatani S, Yamada T, Ishida T, Yamamoto M, Onoue Y, Arima Y, Yamamoto E, Sunagawa Y, Yoshizawa T, Nakagata N, Bober E, Braun T, Sakamoto K, Kaikita K, Morimoto T, Yamagata K, Tsujita K.

Hypertension. 2020 Jan;75(1):98-108. doi: 10.1161/HYPERTENSIONAHA.119.13357. Epub 2019 Nov 18.


Dynamic Axis-Tuned Cells in the Monkey Lateral Prefrontal Cortex during a Path-Planning Task.

Sakamoto K, Saito N, Yoshida S, Mushiake H.

J Neurosci. 2020 Jan 2;40(1):203-219. doi: 10.1523/JNEUROSCI.2526-18.2019. Epub 2019 Nov 12.


Ruxolitinib shows activity against Hodgkin lymphoma but not primary mediastinal large B-cell lymphoma.

Kim SJ, Yoon DH, Kang HJ, Hong JY, Lee HS, Oh SY, Shin HJ, Kong JH, Yi JH, Sakamoto K, Ko YH, Huh J, Lee SS, Takeuchi K, Shin DY, Suh C, Kim WS.

BMC Cancer. 2019 Nov 10;19(1):1080. doi: 10.1186/s12885-019-6303-z.


Addiction of mesenchymal phenotypes on the FGF/FGFR axis in oral squamous cell carcinoma cells.

Osada AH, Endo K, Kimura Y, Sakamoto K, Nakamura R, Sakamoto K, Ueki K, Yoshizawa K, Miyazawa K, Saitoh M.

PLoS One. 2019 Nov 4;14(11):e0217451. doi: 10.1371/journal.pone.0217451. eCollection 2019.


Additional bevacizumab in EGFR-mutant lung adenocarcinoma patients who had oligo-progression after the failure of EGFR-TKI: A single-institute retrospective study.

Kashiwabara K, Fujii S, Tsumura S, Sakamoto K, Semba H.

Cancer Treat Res Commun. 2019 Sep 29;22:100163. doi: 10.1016/j.ctarc.2019.100163. [Epub ahead of print]


Assessment of valgus laxity after release of the medial structure in medial open-wedge high tibial osteotomy: an in vivo biomechanical study using quantitative valgus stress radiography.

Sato D, Kondo E, Yabuuchi K, Onodera J, Onodera T, Yagi T, Sakamoto K, Takasawa A, Iwasaki N, Yasuda K.

BMC Musculoskelet Disord. 2019 Oct 27;20(1):481. doi: 10.1186/s12891-019-2859-7.


Vertical interval between hepatic segment of inferior vena cava and right atrium predicts intraoperative blood loss during hemi-hepatectomy.

Sakamoto K, Ogawa K, Matsui T, Utsunomiya T, Honjo M, Ueno Y, Tamura K, Inoue H, Takai A, Takada Y.

J Hepatobiliary Pancreat Sci. 2019 Oct 21. doi: 10.1002/jhbp.689. [Epub ahead of print]


Wilson Disease With Giant Splenic Artery Aneurysms Caused by Fibromuscular Dysplasia During Living Donor Liver Transplantation: A Case Report.

Sakamoto K, Ogawa K, Tamura K, Ueno Y, Inoue H, Nakamura T, Watanabe J, Takai A, Tohyama T, Senba H, Yoshida O, Abe M, Hiasa Y, Kitazawa R, Kitazawa S, Takada Y.

Transplant Proc. 2019 Nov;51(9):3131-3135. doi: 10.1016/j.transproceed.2019.06.005. Epub 2019 Oct 11.


Hemodialysis vascular access infection caused by Methylobacterium radiotolerans: The first confirmed case in Japan.

Kaneko M, Tominaga Y, Sakamoto K, Shikata H.

J Infect Chemother. 2020 Jan;26(1):107-109. doi: 10.1016/j.jiac.2019.03.028. Epub 2019 Oct 4.


A Trial Protocol of Biweekly TAS-102 and Bevacizumab as Third-Line Chemotherapy for Advanced/Recurrent Colorectal Cancer: A Phase II Multicenter Clinical Trial (The TAS-CC4 Study).

Yoshida Y, Yamada T, Matsuoka H, Sonoda H, Fukazawa A, Yoshida H, Ishida H, Hirata K, Hasegawa S, Sakamoto K, Otsuka T, Koda K.

J Anus Rectum Colon. 2019 Jul 30;3(3):136-141. doi: 10.23922/jarc.2018-043. eCollection 2019.


<Editors' Choice> Renewed Japanese spirometric reference variables and risk stratification for postoperative outcomes in COPD patients with resected lung cancer.

Okada Y, Hashimoto N, Iwano S, Kawaguchi K, Fukui T, Sakamoto K, Wakai K, Yokoi K, Hasegawa Y.

Nagoya J Med Sci. 2019 Aug;81(3):427-438. doi: 10.18999/nagjms.81.3.427.


Serum γ-Glutamyltransferase as a Prognostic Biomarker in Metastatic Castration-resistant Prostate Cancer Treated With Enzalutamide.

Takemura K, Ito M, Nakanishi Y, Kataoka M, Sakamoto K, Suzuki H, Tobisu KI, Koga F.

Anticancer Res. 2019 Oct;39(10):5773-5780. doi: 10.21873/anticanres.13780.


Clinical significance of serum magnesium levels in patients with heart failure with preserved ejection fraction.

Nishihara T, Yamamoto E, Sueta D, Fujisue K, Usuku H, Oike F, Takae M, Arima Y, Araki S, Takashio S, Nakamura T, Suzuki S, Sakamoto K, Soejima H, Kawano H, Kaikita K, Tsujita K.

Medicine (Baltimore). 2019 Sep;98(38):e17069. doi: 10.1097/MD.0000000000017069.


Delusions Without Hallucinations After Midbrain Infarction.

Sakamoto K, Yokoi K, Kawakatsu S, Kobayashi R, Kunihiro K, Okada O, Sato Y, Otani K, Hirayama K.

J Neuropsychiatry Clin Neurosci. 2019 Sep 30:appineuropsych19040097. doi: 10.1176/appi.neuropsych.19040097. [Epub ahead of print] No abstract available.


Exploring the microbiota of upper respiratory tract during the development of pneumonia in a mouse model.

Morinaga Y, Take Y, Sasaki D, Ota K, Kaku N, Uno N, Sakamoto K, Kosai K, Miyazaki T, Hasegawa H, Izumikawa K, Mukae H, Yanagihara K.

PLoS One. 2019 Sep 27;14(9):e0222589. doi: 10.1371/journal.pone.0222589. eCollection 2019.


Transcatheter aortic valve implantation versus conservative management for severe aortic stenosis in real clinical practice.

Takeji Y, Taniguchi T, Morimoto T, Saito N, Ando K, Shirai S, Sakaguchi G, Arai Y, Fuku Y, Kawase Y, Komiya T, Ehara N, Kitai T, Koyama T, Watanabe S, Watanabe H, Shiomi H, Minamino-Muta E, Matsuda S, Yaku H, Yoshikawa Y, Yamazaki K, Kawatou M, Sakamoto K, Tamura T, Miyake M, Sakaguchi H, Murata K, Nakai M, Kanamori N, Izumi C, Mitsuoka H, Kato M, Hirano Y, Inada T, Nagao K, Mabuchi H, Takeuchi Y, Yamane K, Tamura T, Toyofuku M, Ishii M, Inoko M, Ikeda T, Ishii K, Hotta K, Jinnai T, Higashitani N, Kato Y, Inuzuka Y, Morikami Y, Minatoya K, Kimura T; CURRENT AS registry Investigators and the K-TAVI registry Investigators.

PLoS One. 2019 Sep 26;14(9):e0222979. doi: 10.1371/journal.pone.0222979. eCollection 2019.


Virological Factors Associated With the Occurrence of Hepatitis B Virus (HBV) Reactivation in Patients With Resolved HBV Infection Analyzed Through Ultradeep Sequencing.

Sakamoto K, Umemura T, Ito K, Okumura A, Joshita S, Ota M, Sugiyama M, Mizokami M, Yoneda M, Tanaka E.

J Infect Dis. 2020 Jan 14;221(3):400-407. doi: 10.1093/infdis/jiz478.


MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways.

Youn M, Huang H, Chen C, Kam S, Wilkes MC, Chae HD, Sridhar KJ, Greenberg PL, Glader B, Narla A, Lin S, Sakamoto KM.

Blood Adv. 2019 Sep 24;3(18):2751-2763. doi: 10.1182/bloodadvances.2019000537.

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