Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 75


Rhinovirus-induces progression of lung disease in a mouse model of COPD via IL-33/ST2 signaling axis.

Gimenes JA Jr, Srivastava V, ReddyVari H, Kotnala S, Mishra R, Farazuddin M, Li W, Sajjan US.

Clin Sci (Lond). 2019 Apr 29;133(8):983-996. doi: 10.1042/CS20181088. Print 2019 Apr 30.


Rhinovirus and COPD airway epithelium.

Owuor N, Nalamala N, Gimenes JA Jr, Sajjan US.

Pulm Crit Care Med. 2017 Oct;2(3). doi: 10.15761/PCCM.1000139. Epub 2017 Sep 7.


Bioenergetic Responses to Mycobacterium tuberculosis: A Step Closer to Developing a New Therapy to Treat Tuberculosis in Smokers?

Sajjan US.

Am J Respir Cell Mol Biol. 2018 Nov;59(5):527-528. doi: 10.1165/rcmb.2018-0225ED. No abstract available.


NOTCH3 contributes to rhinovirus-induced goblet cell hyperplasia in COPD airway epithelial cells.

Jing Y, Gimenes JA, Mishra R, Pham D, Comstock AT, Yu D, Sajjan U.

Thorax. 2019 Jan;74(1):18-32. doi: 10.1136/thoraxjnl-2017-210593. Epub 2018 Jul 10.


Quercetin prevents rhinovirus-induced progression of lung disease in mice with COPD phenotype.

Farazuddin M, Mishra R, Jing Y, Srivastava V, Comstock AT, Sajjan US.

PLoS One. 2018 Jul 5;13(7):e0199612. doi: 10.1371/journal.pone.0199612. eCollection 2018.


Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis.

Walentek P, Quigley IK, Sun DI, Sajjan UK, Kintner C, Harland RM.

Elife. 2016 Sep 13;5. pii: e17557. doi: 10.7554/eLife.17557.


TLR2 Activation Limits Rhinovirus-Stimulated CXCL-10 by Attenuating IRAK-1-Dependent IL-33 Receptor Signaling in Human Bronchial Epithelial Cells.

Ganesan S, Pham D, Jing Y, Farazuddin M, Hudy MH, Unger B, Comstock AT, Proud D, Lauring AS, Sajjan US.

J Immunol. 2016 Sep 15;197(6):2409-20. doi: 10.4049/jimmunol.1502702. Epub 2016 Aug 8.


Rhinovirus Delays Cell Repolarization in a Model of Injured/Regenerating Human Airway Epithelium.

Faris AN, Ganesan S, Chattoraj A, Chattoraj SS, Comstock AT, Unger BL, Hershenson MB, Sajjan US.

Am J Respir Cell Mol Biol. 2016 Oct;55(4):487-499.


Enhancement of Inducible Nitric Oxide Synthase Activity by Low Molecular Weight Peptides Derived from Protamine: A Potential Therapy for Chronic Rhinosinusitis.

Balijepalli AS, Comstock AT, Wang X, Jensen GC, Hershenson MB, Zacharek MA, Sajjan US, Meyerhoff ME.

Mol Pharm. 2015 Jul 6;12(7):2396-405. doi: 10.1021/acs.molpharmaceut.5b00110. Epub 2015 Jun 2.


Neonatal rhinovirus induces mucous metaplasia and airways hyperresponsiveness through IL-25 and type 2 innate lymphoid cells.

Hong JY, Bentley JK, Chung Y, Lei J, Steenrod JM, Chen Q, Sajjan US, Hershenson MB.

J Allergy Clin Immunol. 2014 Aug;134(2):429-39. doi: 10.1016/j.jaci.2014.04.020. Epub 2014 Jun 6.


Macrophage activation state determines the response to rhinovirus infection in a mouse model of allergic asthma.

Hong JY, Chung Y, Steenrod J, Chen Q, Lei J, Comstock AT, Goldsmith AM, Bentley JK, Sajjan US, Hershenson MB.

Respir Res. 2014 Jun 7;15:63. doi: 10.1186/1465-9921-15-63.


Rhinovirus-induced macrophage cytokine expression does not require endocytosis or replication.

Saba TG, Chung Y, Hong JY, Sajjan US, Bentley JK, Hershenson MB.

Am J Respir Cell Mol Biol. 2014 May;50(5):974-84. doi: 10.1165/rcmb.2013-0354OC.


Barrier function of airway tract epithelium.

Ganesan S, Comstock AT, Sajjan US.

Tissue Barriers. 2013 Oct 1;1(4):e24997. doi: 10.4161/tisb.24997. Epub 2013 May 30. Review.


Differential responses to rhinovirus- and influenza-associated pulmonary exacerbations in patients with cystic fibrosis.

Ramirez IA, Caverly LJ, Kalikin LM, Goldsmith AM, Lewis TC, Burke DT, LiPuma JJ, Sajjan US, Hershenson MB.

Ann Am Thorac Soc. 2014 May;11(4):554-61. doi: 10.1513/AnnalsATS.201310-346OC. Erratum in: Ann Am Thorac Soc. 2015 Jun;12(6):960. Caverly, Lindsay L [corrected to Caverly, Lindsay J].


Combined exposure to cigarette smoke and nontypeable Haemophilus influenzae drives development of a COPD phenotype in mice.

Ganesan S, Comstock AT, Kinker B, Mancuso P, Beck JM, Sajjan US.

Respir Res. 2014 Feb 4;15:11. doi: 10.1186/1465-9921-15-11.


Nod-like receptor X-1 is required for rhinovirus-induced barrier dysfunction in airway epithelial cells.

Unger BL, Ganesan S, Comstock AT, Faris AN, Hershenson MB, Sajjan US.

J Virol. 2014 Apr;88(7):3705-18. doi: 10.1128/JVI.03039-13. Epub 2014 Jan 15.


Repair and Remodeling of airway epithelium after injury in Chronic Obstructive Pulmonary Disease.

Ganesan S, Sajjan US.

Curr Respir Care Rep. 2013 Sep 1;2(3). doi: 10.1007/s13665-013-0052-2.


Rhinovirus colocalizes with CD68- and CD11b-positive macrophages following experimental infection in humans.

Bentley JK, Sajjan US, Dzaman MB, Jarjour NN, Lee WM, Gern JE, Hershenson MB.

J Allergy Clin Immunol. 2013 Sep;132(3):758-761.e3. doi: 10.1016/j.jaci.2013.04.020. Epub 2013 May 31. No abstract available.


Susceptibility to viral infections in chronic obstructive pulmonary disease: role of epithelial cells.

Sajjan US.

Curr Opin Pulm Med. 2013 Mar;19(2):125-32. doi: 10.1097/MCP.0b013e32835cef10. Review.


Aberrantly activated EGFR contributes to enhanced IL-8 expression in COPD airways epithelial cells via regulation of nuclear FoxO3A.

Ganesan S, Unger BL, Comstock AT, Angel KA, Mancuso P, Martinez FJ, Sajjan US.

Thorax. 2013 Feb;68(2):131-41. doi: 10.1136/thoraxjnl-2012-201719. Epub 2012 Oct 25.


Rhinovirus attenuates non-typeable Hemophilus influenzae-stimulated IL-8 responses via TLR2-dependent degradation of IRAK-1.

Unger BL, Faris AN, Ganesan S, Comstock AT, Hershenson MB, Sajjan US.

PLoS Pathog. 2012;8(10):e1002969. doi: 10.1371/journal.ppat.1002969. Epub 2012 Oct 4.


Quercetin inhibits rhinovirus replication in vitro and in vivo.

Ganesan S, Faris AN, Comstock AT, Wang Q, Nanua S, Hershenson MB, Sajjan US.

Antiviral Res. 2012 Jun;94(3):258-71. doi: 10.1016/j.antiviral.2012.03.005. Epub 2012 Mar 23.


Neonatal rhinovirus infection induces mucous metaplasia and airways hyperresponsiveness.

Schneider D, Hong JY, Popova AP, Bowman ER, Linn MJ, McLean AM, Zhao Y, Sonstein J, Bentley JK, Weinberg JB, Lukacs NW, Curtis JL, Sajjan US, Hershenson MB.

J Immunol. 2012 Mar 15;188(6):2894-904. doi: 10.4049/jimmunol.1101391. Epub 2012 Feb 13.


Elastase/LPS-exposed mice exhibit impaired innate immune responses to bacterial challenge: role of scavenger receptor A.

Ganesan S, Faris AN, Comstock AT, Sonstein J, Curtis JL, Sajjan US.

Am J Pathol. 2012 Jan;180(1):61-72. doi: 10.1016/j.ajpath.2011.09.029. Epub 2011 Nov 8.


Induction of Ran GTP drives ciliogenesis.

Fan S, Whiteman EL, Hurd TW, McIntyre JC, Dishinger JF, Liu CJ, Martens JR, Verhey KJ, Sajjan U, Margolis B.

Mol Biol Cell. 2011 Dec;22(23):4539-48. doi: 10.1091/mbc.E11-03-0267. Epub 2011 Oct 12.


Pseudomonas aeruginosa suppresses interferon response to rhinovirus infection in cystic fibrosis but not in normal bronchial epithelial cells.

Chattoraj SS, Ganesan S, Faris A, Comstock A, Lee WM, Sajjan US.

Infect Immun. 2011 Oct;79(10):4131-45. doi: 10.1128/IAI.05120-11. Epub 2011 Aug 8.


Cable pili and the associated 22 kDa adhesin contribute to Burkholderia cenocepacia persistence in vivo.

Goldberg JB, Ganesan S, Comstock AT, Zhao Y, Sajjan US.

PLoS One. 2011;6(7):e22435. doi: 10.1371/journal.pone.0022435. Epub 2011 Jul 21.


Resident tissue-specific mesenchymal progenitor cells contribute to fibrogenesis in human lung allografts.

Walker N, Badri L, Wettlaufer S, Flint A, Sajjan U, Krebsbach PH, Keshamouni VG, Peters-Golden M, Lama VN.

Am J Pathol. 2011 Jun;178(6):2461-9. doi: 10.1016/j.ajpath.2011.01.058.


MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness.

Wang Q, Miller DJ, Bowman ER, Nagarkar DR, Schneider D, Zhao Y, Linn MJ, Goldsmith AM, Bentley JK, Sajjan US, Hershenson MB.

PLoS Pathog. 2011 May;7(5):e1002070. doi: 10.1371/journal.ppat.1002070. Epub 2011 May 26.


Rhinovirus-induced barrier dysfunction in polarized airway epithelial cells is mediated by NADPH oxidase 1.

Comstock AT, Ganesan S, Chattoraj A, Faris AN, Margolis BL, Hershenson MB, Sajjan US.

J Virol. 2011 Jul;85(13):6795-808. doi: 10.1128/JVI.02074-10. Epub 2011 Apr 20.


Rhinovirus infection liberates planktonic bacteria from biofilm and increases chemokine responses in cystic fibrosis airway epithelial cells.

Chattoraj SS, Ganesan S, Jones AM, Helm JM, Comstock AT, Bright-Thomas R, LiPuma JJ, Hershenson MB, Sajjan US.

Thorax. 2011 Apr;66(4):333-9. doi: 10.1136/thx.2010.151431. Epub 2011 Feb 2.


Host evasion by Burkholderia cenocepacia.

Ganesan S, Sajjan US.

Front Cell Infect Microbiol. 2012 Jan 11;1:25. doi: 10.3389/fcimb.2011.00025. eCollection 2011. Review.


Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression.

Ganesan S, Faris AN, Comstock AT, Chattoraj SS, Chattoraj A, Burgess JR, Curtis JL, Martinez FJ, Zick S, Hershenson MB, Sajjan US.

Respir Res. 2010 Sep 28;11:131. doi: 10.1186/1465-9921-11-131.


Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages.

Nagarkar DR, Bowman ER, Schneider D, Wang Q, Shim J, Zhao Y, Linn MJ, McHenry CL, Gosangi B, Bentley JK, Tsai WC, Sajjan US, Lukacs NW, Hershenson MB.

J Immunol. 2010 Aug 15;185(4):2525-35. doi: 10.4049/jimmunol.1000286. Epub 2010 Jul 19.


Increased cytokine response of rhinovirus-infected airway epithelial cells in chronic obstructive pulmonary disease.

Schneider D, Ganesan S, Comstock AT, Meldrum CA, Mahidhara R, Goldsmith AM, Curtis JL, Martinez FJ, Hershenson MB, Sajjan U.

Am J Respir Crit Care Med. 2010 Aug 1;182(3):332-40. doi: 10.1164/rccm.200911-1673OC. Epub 2010 Apr 15.


Pseudomonas aeruginosa alginate promotes Burkholderia cenocepacia persistence in cystic fibrosis transmembrane conductance regulator knockout mice.

Chattoraj SS, Murthy R, Ganesan S, Goldberg JB, Zhao Y, Hershenson MB, Sajjan US.

Infect Immun. 2010 Mar;78(3):984-93. doi: 10.1128/IAI.01192-09. Epub 2010 Jan 4.


Efficacy of bacteriophage therapy in a model of Burkholderia cenocepacia pulmonary infection.

Carmody LA, Gill JJ, Summer EJ, Sajjan US, Gonzalez CF, Young RF, LiPuma JJ.

J Infect Dis. 2010 Jan 15;201(2):264-71. doi: 10.1086/649227.


Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.

Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB.

J Immunol. 2009 Dec 1;183(11):6989-97. doi: 10.4049/jimmunol.0901386. Epub 2009 Nov 4.


CXCR2 is required for neutrophilic airway inflammation and hyperresponsiveness in a mouse model of human rhinovirus infection.

Nagarkar DR, Wang Q, Shim J, Zhao Y, Tsai WC, Lukacs NW, Sajjan U, Hershenson MB.

J Immunol. 2009 Nov 15;183(10):6698-707. doi: 10.4049/jimmunol.0900298. Epub 2009 Oct 28.


Elastase- and LPS-exposed mice display altered responses to rhinovirus infection.

Sajjan U, Ganesan S, Comstock AT, Shim J, Wang Q, Nagarkar DR, Zhao Y, Goldsmith AM, Sonstein J, Linn MJ, Curtis JL, Hershenson MB.

Am J Physiol Lung Cell Mol Physiol. 2009 Nov;297(5):L931-44. doi: 10.1152/ajplung.00150.2009. Epub 2009 Sep 11.


Azithromycin increases survival and reduces lung inflammation in cystic fibrosis mice.

Tsai WC, Hershenson MB, Zhou Y, Sajjan U.

Inflamm Res. 2009 Aug;58(8):491-501. doi: 10.1007/s00011-009-0015-9. Epub 2009 Mar 7.


Rhinovirus disrupts the barrier function of polarized airway epithelial cells.

Sajjan U, Wang Q, Zhao Y, Gruenert DC, Hershenson MB.

Am J Respir Crit Care Med. 2008 Dec 15;178(12):1271-81. doi: 10.1164/rccm.200801-136OC. Epub 2008 Sep 11.


Human rhinovirus 1B exposure induces phosphatidylinositol 3-kinase-dependent airway inflammation in mice.

Newcomb DC, Sajjan US, Nagarkar DR, Wang Q, Nanua S, Zhou Y, McHenry CL, Hennrick KT, Tsai WC, Bentley JK, Lukacs NW, Johnston SL, Hershenson MB.

Am J Respir Crit Care Med. 2008 May 15;177(10):1111-21. doi: 10.1164/rccm.200708-1243OC. Epub 2008 Feb 14.


Burkholderia cenocepacia ET12 strain activates TNFR1 signalling in cystic fibrosis airway epithelial cells.

Sajjan US, Hershenson MB, Forstner JF, LiPuma JJ.

Cell Microbiol. 2008 Jan;10(1):188-201. Epub 2007 Aug 14.


Cooperative effects of rhinovirus and TNF-{alpha} on airway epithelial cell chemokine expression.

Newcomb DC, Sajjan US, Nagarkar DR, Goldsmith AM, Bentley JK, Hershenson MB.

Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L1021-8. Epub 2007 Jul 13.


Lung cells from neonates show a mesenchymal stem cell phenotype.

Hennrick KT, Keeton AG, Nanua S, Kijek TG, Goldsmith AM, Sajjan US, Bentley JK, Lama VN, Moore BB, Schumacher RE, Thannickal VJ, Hershenson MB.

Am J Respir Crit Care Med. 2007 Jun 1;175(11):1158-64. Epub 2007 Mar 1.


Rhinovirus activates interleukin-8 expression via a Src/p110beta phosphatidylinositol 3-kinase/Akt pathway in human airway epithelial cells.

Bentley JK, Newcomb DC, Goldsmith AM, Jia Y, Sajjan US, Hershenson MB.

J Virol. 2007 Feb;81(3):1186-94. Epub 2006 Nov 22.


Intracellular trafficking and replication of Burkholderia cenocepacia in human cystic fibrosis airway epithelial cells.

Sajjan US, Yang JH, Hershenson MB, LiPuma JJ.

Cell Microbiol. 2006 Sep;8(9):1456-66.


H. influenzae potentiates airway epithelial cell responses to rhinovirus by increasing ICAM-1 and TLR3 expression.

Sajjan US, Jia Y, Newcomb DC, Bentley JK, Lukacs NW, LiPuma JJ, Hershenson MB.

FASEB J. 2006 Oct;20(12):2121-3. Epub 2006 Aug 16.


Quercetin blocks airway epithelial cell chemokine expression.

Nanua S, Zick SM, Andrade JE, Sajjan US, Burgess JR, Lukacs NW, Hershenson MB.

Am J Respir Cell Mol Biol. 2006 Nov;35(5):602-10. Epub 2006 Jun 22.

Supplemental Content

Loading ...
Support Center