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Items: 1 to 50 of 662

1.

Initial evaluation of PET/CT with 18 F-FSU-880 targeting prostate-specific membrane antigen in prostate cancer patients.

Saga T, Nakamoto Y, Ishimori T, Inoue T, Shimizu Y, Kimura H, Akamatsu S, Goto T, Watanabe H, Kitaguchi K, Watanabe M, Ono M, Saji H, Ogawa O, Togashi K.

Cancer Sci. 2019 Feb;110(2):742-750. doi: 10.1111/cas.13911. Epub 2019 Jan 4.

2.

The Society for Translational Medicine: indications and methods of percutaneous transthoracic needle biopsy for diagnosis of lung cancer.

Zhou Q, Dong J, He J, Liu D, Tian DH, Gao S, Li S, Liu L, He J, Huang Y, Xu S, Mao W, Tan Q, Chen C, Li X, Zhang Z, Jiang G, Xu L, Zhang L, Fu J, Li H, Wang Q, Tan L, Li D, Zhou Q, Fu X, Jiang Z, Chen H, Fang W, Zhang X, Li Y, Tong T, Yu Z, Liu Y, Zhi X, Yan T, Zhang X, Casal RF, Pompeo E, Carretta A, Riquet M, Rena O, Falcoz PE, Saji H, Khan AZ, Danguilan JL, Gonzalez-Rivas D, Guibert N, Zhu C, Shen J.

J Thorac Dis. 2018 Sep;10(9):5538-5544. doi: 10.21037/jtd.2018.09.28. Review. No abstract available.

3.

Characterization of Novel 18F-Labeled Phenoxymethylpyridine Derivatives as Amylin Imaging Probes.

Watanabe H, Yoshimura M, Sano K, Shimizu Y, Kaide S, Nakamoto Y, Togashi K, Ono M, Saji H.

Mol Pharm. 2018 Nov 8. doi: 10.1021/acs.molpharmaceut.8b00756. [Epub ahead of print]

PMID:
30407835
4.

Effects of HLA mismatch on cytomegalovirus reactivation in cord blood transplantation.

Yokoyama H, Kanda J, Kato S, Kondo E, Maeda Y, Saji H, Takahashi S, Onizuka M, Onishi Y, Ozawa Y, Kanamori H, Ishikawa J, Ohno Y, Ichinohe T, Takanashi M, Kato K, Atsuta Y, Kanda Y; HLA Working Group of the Japan Society for Hematopoietic Cell Transplantation.

Bone Marrow Transplant. 2018 Nov 6. doi: 10.1038/s41409-018-0369-0. [Epub ahead of print]

PMID:
30401965
5.

PD-L1 Expression in Non-Small-Cell Lung Cancer Including Various Adenocarcinoma Subtypes.

Miyazawa T, Marushima H, Saji H, Kojima K, Hoshikawa M, Takagi M, Nakamura H.

Ann Thorac Cardiovasc Surg. 2018 Oct 3. doi: 10.5761/atcs.oa.18-00163. [Epub ahead of print]

6.

A variant at 9q34.11 is associated with HLA-DQB1*06:02 negative essential hypersomnia.

Miyagawa T, Khor SS, Toyoda H, Kanbayashi T, Imanishi A, Sagawa Y, Kotorii N, Kotorii T, Ariyoshi Y, Hashizume Y, Ogi K, Hiejima H, Kamei Y, Hida A, Miyamoto M, Ikegami A, Wada Y, Takami M, Higashiyama Y, Miyake R, Kondo H, Fujimura Y, Tamura Y, Taniyama Y, Omata N, Tanaka Y, Moriya S, Furuya H, Kato M, Kawamura Y, Otowa T, Miyashita A, Kojima H, Saji H, Shimada M, Yamasaki M, Kobayashi T, Misawa R, Shigematsu Y, Kuwano R, Sasaki T, Ishigooka J, Wada Y, Tsuruta K, Chiba S, Tanaka F, Yamada N, Okawa M, Kuroda K, Kume K, Hirata K, Uchimura N, Shimizu T, Inoue Y, Honda Y, Mishima K, Honda M, Tokunaga K.

J Hum Genet. 2018 Dec;63(12):1259-1267. doi: 10.1038/s10038-018-0518-8. Epub 2018 Sep 28.

PMID:
30266950
7.

Novel fluorescence probes based on the chalcone scaffold for in vitro staining of β-amyloid plaques.

Watanabe H, Saji H, Ono M.

Bioorg Med Chem Lett. 2018 Oct 15;28(19):3242-3246. doi: 10.1016/j.bmcl.2018.08.009. Epub 2018 Aug 8.

PMID:
30131243
8.

Evaluation of the Relationship Between Cognitive Impairment, Glycometabolism, and Nicotinic Acetylcholine Receptor Deficits in a Mouse Model of Alzheimer's Disease.

Matsuura Y, Ueda M, Higaki Y, Sano K, Saji H, Enomoto S.

Mol Imaging Biol. 2018 Jul 25. doi: 10.1007/s11307-018-1253-4. [Epub ahead of print]

PMID:
30047036
9.

Enhanced Delivery of Radiolabeled Polyoxazoline into Tumors via Self-Aggregation under Hyperthermic Conditions.

Sano K, Kanada Y, Takahashi K, Ding N, Kanazaki K, Mukai T, Ono M, Saji H.

Mol Pharm. 2018 Sep 4;15(9):3997-4003. doi: 10.1021/acs.molpharmaceut.8b00441. Epub 2018 Aug 13.

PMID:
30036483
10.

Establishment of a method for in-vivo SPECT/CT imaging analysis of 111In-labeled exendin-4 pancreatic uptake in mice without the need for nephrectomy or a secondary probe.

Hamamatsu K, Fujimoto H, Fujita N, Murakami T, Kimura H, Saji H, Inagaki N.

Nucl Med Biol. 2018 Sep - Oct;64-65:22-27. doi: 10.1016/j.nucmedbio.2018.06.002. Epub 2018 Jun 8.

PMID:
30015092
11.

Synthesis and evaluation of a [18F]formyl-Met-Leu-Phe derivative: A positron emission tomography imaging probe for bacterial infections.

Kimura H, Yamauchi S, Kawashima H, Arimitsu K, Yagi Y, Nakamoto Y, Togashi K, Ono M, Saji H.

Bioorg Med Chem Lett. 2018 Sep 15;28(17):2949-2952. doi: 10.1016/j.bmcl.2018.07.009. Epub 2018 Jul 6.

PMID:
30006064
12.

Cancer radiotheranostics targeting carbonic anhydrase-IX with 111In- and 90Y-labeled ureidosulfonamide scaffold for SPECT imaging and radionuclide-based therapy.

Iikuni S, Ono M, Watanabe H, Shimizu Y, Sano K, Saji H.

Theranostics. 2018 Apr 30;8(11):2992-3006. doi: 10.7150/thno.20982. eCollection 2018.

13.

Differential Proteomic Analysis between Small Cell Lung Carcinoma (SCLC) and Pulmonary Carcinoid Tumors Reveals Molecular Signatures for Malignancy in Lung Cancer.

Fujii K, Miyata Y, Takahashi I, Koizumi H, Saji H, Hoshikawa M, Takagi M, Nishimura T, Nakamura H.

Proteomics Clin Appl. 2018 Nov;12(6):e1800015. doi: 10.1002/prca.201800015. Epub 2018 Jul 5.

PMID:
29888431
14.

Activatable fluorescence imaging of macrophages in atherosclerotic plaques using iron oxide nanoparticles conjugated with indocyanine green.

Ikeda H, Ishii A, Sano K, Chihara H, Arai D, Abekura Y, Nishi H, Ono M, Saji H, Miyamoto S.

Atherosclerosis. 2018 Aug;275:1-10. doi: 10.1016/j.atherosclerosis.2018.05.028. Epub 2018 May 18.

PMID:
29852399
15.

Improved lymph node staging in early-stage lung cancer in the national cancer database: commentary.

Saji H, Kojima K, Nakamura H.

J Thorac Dis. 2018 Apr;10(Suppl 9):S1092-S1095. doi: 10.21037/jtd.2018.04.36. No abstract available.

16.

Structure-Activity Relationships of Radioiodinated Benzoimidazopyridine Derivatives for Detection of Tau Pathology.

Kaide S, Ono M, Watanabe H, Kitada A, Yoshimura M, Shimizu Y, Ihara M, Saji H.

ACS Med Chem Lett. 2018 Apr 10;9(5):478-483. doi: 10.1021/acsmedchemlett.8b00092. eCollection 2018 May 10.

PMID:
29795763
17.

Conversion of iodine to fluorine-18 based on iodinated chalcone and evaluation for β-amyloid PET imaging.

Kaide S, Ono M, Watanabe H, Shimizu Y, Nakamoto Y, Togashi K, Yamaguchi A, Hanaoka H, Saji H.

Bioorg Med Chem. 2018 Jul 23;26(12):3352-3358. doi: 10.1016/j.bmc.2018.05.001. Epub 2018 May 3.

PMID:
29751990
18.

Allelic Polymorphisms of KIRs and HLAs Predict Favorable Responses to Tyrosine Kinase Inhibitors in CML.

Ureshino H, Shindo T, Kojima H, Kusunoki Y, Miyazaki Y, Tanaka H, Saji H, Kawaguchi A, Kimura S.

Cancer Immunol Res. 2018 Jun;6(6):745-754. doi: 10.1158/2326-6066.CIR-17-0462. Epub 2018 Apr 25.

PMID:
29695383
19.

Comparison of 125I- and 111In-labeled peptide probes for in vivo detection of oxidized low-density lipoprotein in atherosclerotic plaques.

Temma T, Kondo N, Yoda K, Nishigori K, Onoe S, Shiomi M, Ono M, Saji H.

Ann Nucl Med. 2018 Jul;32(6):425-429. doi: 10.1007/s12149-018-1255-y. Epub 2018 Apr 12.

PMID:
29651757
20.

Prognostic factors for surgically resected non-small cell lung cancer with cavity formation.

Shigefuku S, Kudo Y, Yunaiyama D, Matsubayashi J, Park J, Nagao T, Shimada Y, Saji H, Hagiwara M, Okano T, Kakihana M, Kajiwara N, Ohira T, Ikeda N.

J Thorac Dis. 2018 Feb;10(2):973-983. doi: 10.21037/jtd.2018.01.61.

21.

Structure-activity relationships of succinimidyl-Cys-C(O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen.

Matsuoka D, Watanabe H, Shimizu Y, Kimura H, Yagi Y, Kawai R, Ono M, Saji H.

Bioorg Med Chem. 2018 May 15;26(9):2291-2301. doi: 10.1016/j.bmc.2018.03.015. Epub 2018 Mar 10.

PMID:
29580851
22.

PET probe detecting non-small cell lung cancer susceptible to epidermal growth factor receptor tyrosine kinase inhibitor therapy.

Makino A, Miyazaki A, Tomoike A, Kimura H, Arimitsu K, Hirata M, Ohmomo Y, Nishii R, Okazawa H, Kiyono Y, Ono M, Saji H.

Bioorg Med Chem. 2018 May 1;26(8):1609-1613. doi: 10.1016/j.bmc.2018.02.007. Epub 2018 Feb 8.

PMID:
29478801
23.

18F-FPYBF-2, a new F-18 labelled amyloid imaging PET tracer: biodistribution and radiation dosimetry assessment of first-in-man 18F-FPYBF-2 PET imaging.

Nishii R, Higashi T, Kagawa S, Okuyama C, Kishibe Y, Takahashi M, Okina T, Suzuki N, Hasegawa H, Nagahama Y, Ishizu K, Oishi N, Kimura H, Watanabe H, Ono M, Saji H, Yamauchi H.

Ann Nucl Med. 2018 May;32(4):256-263. doi: 10.1007/s12149-018-1240-5. Epub 2018 Feb 16.

PMID:
29453681
24.

HLA-DRB1 Analysis Identified a Genetically Unique Subset within Rheumatoid Arthritis and Distinct Genetic Background of Rheumatoid Factor Levels from Anticyclic Citrullinated Peptide Antibodies.

Hiwa R, Ikari K, Ohmura K, Nakabo S, Matsuo K, Saji H, Yurugi K, Miura Y, Maekawa T, Taniguchi A, Yamanaka H, Matsuda F, Mimori T, Terao C.

J Rheumatol. 2018 Apr;45(4):470-480. doi: 10.3899/jrheum.170363. Epub 2018 Feb 1.

PMID:
29419463
25.

18F-FPYBF-2, a new F-18-labelled amyloid imaging PET tracer: first experience in 61 volunteers and 55 patients with dementia.

Higashi T, Nishii R, Kagawa S, Kishibe Y, Takahashi M, Okina T, Suzuki N, Hasegawa H, Nagahama Y, Ishizu K, Oishi N, Kimura H, Watanabe H, Ono M, Saji H, Yamauchi H.

Ann Nucl Med. 2018 Apr;32(3):206-216. doi: 10.1007/s12149-018-1236-1. Epub 2018 Jan 31.

26.

Core Binding Site of a Thioflavin-T-Derived Imaging Probe on Amyloid β Fibrils Predicted by Computational Methods.

Kawai R, Araki M, Yoshimura M, Kamiya N, Ono M, Saji H, Okuno Y.

ACS Chem Neurosci. 2018 May 16;9(5):957-966. doi: 10.1021/acschemneuro.7b00389. Epub 2018 Jan 30.

PMID:
29381047
27.

Evaluation of 18F-labeled exendin(9-39) derivatives targeting glucagon-like peptide-1 receptor for pancreatic β-cell imaging.

Kimura H, Ogawa Y, Fujimoto H, Mukai E, Kawashima H, Arimitsu K, Toyoda K, Fujita N, Yagi Y, Hamamatsu K, Murakami T, Murakami A, Ono M, Nakamoto Y, Togashi K, Inagaki N, Saji H.

Bioorg Med Chem. 2018 Jan 15;26(2):463-469. doi: 10.1016/j.bmc.2017.12.007. Epub 2017 Dec 5.

PMID:
29273416
28.

A proposal for a comprehensive risk scoring system for predicting postoperative complications in octogenarian patients with medically operable lung cancer: JACS1303.

Saji H, Ueno T, Nakamura H, Okumura N, Tsuchida M, Sonobe M, Miyazaki T, Aokage K, Nakao M, Haruki T, Ito H, Kataoka K, Okabe K, Tomizawa K, Yoshimoto K, Horio H, Sugio K, Ode Y, Takao M, Okada M, Chida M; Committee for Scientific Affairs, The Japanese Association for Chest Surgery, Tokyo, Japan.

Eur J Cardiothorac Surg. 2018 Apr 1;53(4):835-841. doi: 10.1093/ejcts/ezx415.

PMID:
29240884
29.

Worse survival after curative resection in patients with pathological stage I non-small cell lung cancer adjoining pulmonary cavity formation.

Kimura H, Saji H, Miyazawa T, Sakai H, Tsuda M, Wakiyama Y, Marushima H, Kojima K, Nakamura H.

J Thorac Dis. 2017 Sep;9(9):3038-3044. doi: 10.21037/jtd.2017.08.42.

30.

Flumioxazin metabolism in pregnant animals and cell-based protoporphyrinogen IX oxidase (PPO) inhibition assay of fetal metabolites in various animal species to elucidate the mechanism of the rat-specific developmental toxicity.

Abe J, Isobe N, Mikata K, Nagahori H, Naito Y, Saji H, Ono M, Kawamura S.

Toxicol Appl Pharmacol. 2018 Jan 15;339:34-41. doi: 10.1016/j.taap.2017.11.028. Epub 2017 Dec 2.

PMID:
29198728
31.

A randomized Phase III trial of lobe-specific vs. systematic nodal dissection for clinical Stage I-II non-small cell lung cancer (JCOG1413).

Hishida T, Saji H, Watanabe SI, Asamura H, Aokage K, Mizutani T, Wakabayashi M, Shibata T, Okada M; Lung Cancer Surgical Study Group of the Japan Clinical Oncology Group (JCOG-LCSSG).

Jpn J Clin Oncol. 2018 Feb 1;48(2):190-194. doi: 10.1093/jjco/hyx170.

PMID:
29177507
32.

Accuracy of the cobas EGFR Mutation Assay in Non-small-cell Lung Cancer Compared With Three Laboratory-developed Tests.

Nakamura H, Koizumi H, Sakai H, Kimura H, Miyazawa T, Marushima H, Saji H, Takagi M.

Clin Lung Cancer. 2018 Mar;19(2):170-174. doi: 10.1016/j.cllc.2017.10.015. Epub 2017 Oct 28.

PMID:
29150249
33.

Neoadjuvant and adjuvant therapy for Stage III non-small cell lung cancer.

Watanabe SI, Nakagawa K, Suzuki K, Takamochi K, Ito H, Okami J, Aokage K, Saji H, Yoshioka H, Zenke Y, Aoki T, Tsutani Y, Okada M; Lung Cancer Surgical Study Group (LCSSG) of the Japan Clinical Oncology Group (JCOG).

Jpn J Clin Oncol. 2017 Dec 1;47(12):1112-1118. doi: 10.1093/jjco/hyx147. Review.

PMID:
29136212
34.

Synthesis and biological evaluation of novel radioiodinated benzimidazole derivatives for imaging α-synuclein aggregates.

Watanabe H, Ariyoshi T, Ozaki A, Ihara M, Ono M, Saji H.

Bioorg Med Chem. 2017 Dec 15;25(24):6398-6403. doi: 10.1016/j.bmc.2017.10.010. Epub 2017 Oct 14.

PMID:
29111367
35.

Different EGFR gene mutations in two patients with synchronous multiple lung cancers: A case report.

Sakai H, Saji H, Kimura H, Tsuda M, Wakiyama Y, Miyazawa T, Marushima H, Kojima K, Hoshikawa M, Takagi M, Nakamura H.

Thorac Cancer. 2018 Jan;9(1):189-192. doi: 10.1111/1759-7714.12554. Epub 2017 Nov 1.

36.

Survival significance of coexisting chronic obstructive pulmonary disease in patients with early lung cancer after curative surgery.

Saji H, Miyazawa T, Sakai H, Kimura Y, Tsuda M, Wakiyama Y, Marushima H, Kojima K, Nakamura H.

Thorac Cancer. 2018 Jan;9(1):19-24. doi: 10.1111/1759-7714.12507. Epub 2017 Oct 4.

37.

Construction of nanostructured DNA harbouring phosphorodiamidate morpholino oligonucleotide for controlled tissue distribution in mice.

Takahashi Y, Araie Y, Nomura D, Takahashi Y, Sano K, Saji H, Takakura Y, Nishikawa M.

J Drug Target. 2018 Apr;26(4):373-381. doi: 10.1080/1061186X.2017.1387789. Epub 2017 Oct 18.

PMID:
28972806
38.

In Vivo Molecular Imaging.

Saji H.

Biol Pharm Bull. 2017;40(10):1605-1615. doi: 10.1248/bpb.b17-00505. Review.

39.

Difference in Postsurgical Prognostic Factors between Lung Adenocarcinoma and Squamous Cell Carcinoma.

Nakamura H, Sakai H, Kimura H, Miyazawa T, Marushima H, Saji H.

Ann Thorac Cardiovasc Surg. 2017 Dec 20;23(6):291-297. doi: 10.5761/atcs.oa.17-00020. Epub 2017 Oct 2.

40.

Synthesis and evaluation of a novel near-infrared fluorescent probe based on succinimidyl-Cys-C(O)-Glu that targets prostate-specific membrane antigen for optical imaging.

Matsuoka D, Watanabe H, Shimizu Y, Kimura H, Ono M, Saji H.

Bioorg Med Chem Lett. 2017 Nov 1;27(21):4876-4880. doi: 10.1016/j.bmcl.2017.09.037. Epub 2017 Sep 18.

PMID:
28964633
41.

Synthesis and biological evaluation of an 111In-labeled exendin-4 derivative as a single-photon emission computed tomography probe for imaging pancreatic β-cells.

Kimura H, Fujita N, Kanbe K, Matsuda H, Watanabe H, Arimitsu K, Fujimoto H, Hamamatsu K, Yagi Y, Ono M, Inagaki N, Saji H.

Bioorg Med Chem. 2017 Oct 15;25(20):5772-5778. doi: 10.1016/j.bmc.2017.09.005. Epub 2017 Sep 7.

PMID:
28927802
42.

NK Cell Alloreactivity against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous iPSCs.

Ichise H, Nagano S, Maeda T, Miyazaki M, Miyazaki Y, Kojima H, Yawata N, Yawata M, Tanaka H, Saji H, Masuda K, Kawamoto H.

Stem Cell Reports. 2017 Sep 12;9(3):853-867. doi: 10.1016/j.stemcr.2017.07.020. Epub 2017 Aug 31.

43.

Survival significance of epidermal growth factor receptor tyrosine kinase inhibitors and current staging system for survival after recurrence in patients with completely resected lung adenocarcinoma.

Saji H, Sakai H, Kimura H, Miyazawa T, Marushima H, Nakamura H.

Onco Targets Ther. 2017 Aug 21;10:4135-4141. doi: 10.2147/OTT.S136569. eCollection 2017.

44.

Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells.

Matsumoto A, Takahashi Y, Nishikawa M, Sano K, Morishita M, Charoenviriyakul C, Saji H, Takakura Y.

Cancer Sci. 2017 Sep;108(9):1803-1810. doi: 10.1111/cas.13310. Epub 2017 Jul 21.

45.

Highly functional T-cell receptor repertoires are abundant in stem memory T cells and highly shared among individuals.

Miyama T, Kawase T, Kitaura K, Chishaki R, Shibata M, Oshima K, Hamana H, Kishi H, Muraguchi A, Kuzushima K, Saji H, Shin-I T, Suzuki R, Ichinohe T.

Sci Rep. 2017 Jun 16;7(1):3663. doi: 10.1038/s41598-017-03855-x.

46.

Comment on prognostic value of epidermal growth factor receptor mutation subtypes in surgically resected non-small cell lung cancer.

Kudo Y, Shimada Y, Saji H, Ikeda N.

J Thorac Dis. 2017 May;9(5):E499-E502. doi: 10.21037/jtd.2017.03.62. No abstract available.

47.

Radioiodination of BODIPY and its application to a nuclear and optical dual functional labeling agent for proteins and peptides.

Ono M, Watanabe H, Ikehata Y, Ding N, Yoshimura M, Sano K, Saji H.

Sci Rep. 2017 Jun 13;7(1):3337. doi: 10.1038/s41598-017-03419-z.

48.

Feasibility study of adjuvant chemotherapy with modified weekly nab-paclitaxel and carboplatin for completely resected non-small-cell lung cancer: FAST-nab.

Saji H, Marushima H, Miyazawa T, Sakai H, Kimura H, Kurimoto N, Nakamura H.

Anticancer Drugs. 2017 Aug;28(7):795-800. doi: 10.1097/CAD.0000000000000512.

PMID:
28538017
49.

Novel Benzothiazole Derivatives as Fluorescent Probes for Detection of β-Amyloid and α-Synuclein Aggregates.

Watanabe H, Ono M, Ariyoshi T, Katayanagi R, Saji H.

ACS Chem Neurosci. 2017 Aug 16;8(8):1656-1662. doi: 10.1021/acschemneuro.6b00450. Epub 2017 May 3.

PMID:
28467708
50.

Pathological upstaging and treatment strategy of clinical stage I small cell lung cancer following surgery.

Saji H, Miyazawa T, Marushima H, Nakamura H.

J Thorac Dis. 2017 Mar;9(3):E285-E289. doi: 10.21037/jtd.2017.03.51. No abstract available.

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