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Items: 11

1.

Recurrent Mutations in the MTOR Regulator RRAGC in Follicular Lymphoma.

Ying ZX, Jin M, Peterson LF, Bernard D, Saiya-Cork K, Yildiz M, Wang S, Kaminski MS, Chang AE, Klionsky DJ, Malek SN.

Clin Cancer Res. 2016 Nov 1;22(21):5383-5393. Epub 2016 Jun 7.

2.

Cell-Intrinsic Determinants of Ibrutinib-Induced Apoptosis in Chronic Lymphocytic Leukemia.

Amin NA, Balasubramanian S, Saiya-Cork K, Shedden K, Hu N, Malek SN.

Clin Cancer Res. 2017 Feb 15;23(4):1049-1059. doi: 10.1158/1078-0432.CCR-15-2921. Epub 2016 Aug 17.

3.

A Quantitative Analysis of Subclonal and Clonal Gene Mutations before and after Therapy in Chronic Lymphocytic Leukemia.

Amin NA, Seymour E, Saiya-Cork K, Parkin B, Shedden K, Malek SN.

Clin Cancer Res. 2016 Sep 1;22(17):4525-35. doi: 10.1158/1078-0432.CCR-15-3103. Epub 2016 Apr 8.

4.

Integrated genomic profiling, therapy response, and survival in adult acute myelogenous leukemia.

Parkin B, Ouillette P, Yildiz M, Saiya-Cork K, Shedden K, Malek SN.

Clin Cancer Res. 2015 May 1;21(9):2045-56. doi: 10.1158/1078-0432.CCR-14-0921. Epub 2015 Feb 4.

5.

Activating STAT6 mutations in follicular lymphoma.

Yildiz M, Li H, Bernard D, Amin NA, Ouillette P, Jones S, Saiya-Cork K, Parkin B, Jacobi K, Shedden K, Wang S, Chang AE, Kaminski MS, Malek SN.

Blood. 2015 Jan 22;125(4):668-79. doi: 10.1182/blood-2014-06-582650. Epub 2014 Nov 26.

6.

Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.

Li H, Kaminski MS, Li Y, Yildiz M, Ouillette P, Jones S, Fox H, Jacobi K, Saiya-Cork K, Bixby D, Lebovic D, Roulston D, Shedden K, Sabel M, Marentette L, Cimmino V, Chang AE, Malek SN.

Blood. 2014 Mar 6;123(10):1487-98. doi: 10.1182/blood-2013-05-500264. Epub 2014 Jan 16.

7.

Clonal evolution, genomic drivers, and effects of therapy in chronic lymphocytic leukemia.

Ouillette P, Saiya-Cork K, Seymour E, Li C, Shedden K, Malek SN.

Clin Cancer Res. 2013 Jun 1;19(11):2893-904. doi: 10.1158/1078-0432.CCR-13-0138. Epub 2013 Apr 25.

8.

A pathobiological role of the insulin receptor in chronic lymphocytic leukemia.

Saiya-Cork K, Collins R, Parkin B, Ouillette P, Kuizon E, Kujawski L, Erba H, Campagnaro E, Shedden K, Kaminski M, Malek SN.

Clin Cancer Res. 2011 May 1;17(9):2679-92. doi: 10.1158/1078-0432.CCR-10-2058. Epub 2011 Feb 9.

9.

Inhibitors of blood coagulation factors Xa and IIa synergize to reduce thrombus weight and thrombin generation in vivo and in vitro.

Gould WR, McClanahan TB, Welch KM, Baxi SM, Saiya-Cork K, Chi L, Johnson TR, Leadley RJ.

J Thromb Haemost. 2006 Apr;4(4):834-41.

10.

The discovery of fluoropyridine-based inhibitors of the factor VIIa/TF complex--Part 2.

Kohrt JT, Filipski KJ, Cody WL, Cai C, Dudley DA, Van Huis CA, Willardsen JA, Narasimhan LS, Zhang E, Rapundalo ST, Saiya-Cork K, Leadley RJ, Edmunds JJ.

Bioorg Med Chem Lett. 2006 Feb 15;16(4):1060-4. Epub 2005 Nov 11.

PMID:
16289811
11.

The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex.

Kohrt JT, Filipski KJ, Cody WL, Cai C, Dudley DA, Van Huis CA, Willardsen JA, Rapundalo ST, Saiya-Cork K, Leadley RJ, Narasimhan L, Zhang E, Whitlow M, Adler M, McLean K, Chou YL, McKnight C, Arnaiz DO, Shaw KJ, Light DR, Edmunds JJ.

Bioorg Med Chem Lett. 2005 Nov 1;15(21):4752-6.

PMID:
16125385

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