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Items: 1 to 50 of 1295

1.

Role of NS5A-L31/Y93 Double Wild-type in Failure of Glecaprevir/Pibrentasvir Double Therapy in Two Patients with a History of Direct-acting Antiviral Agent Failure: An Ultra-deep Sequencing Analysis.

Sano T, Akuta N, Suzuki F, Kasuya K, Fujiyama S, Kawamura Y, Sezaki H, Hosaka T, Saitoh S, Kobayashi M, Suzuki Y, Kobayashi M, Arase Y, Ikeda K, Kumada H.

Intern Med. 2019 Jun 7. doi: 10.2169/internalmedicine.2604-18. [Epub ahead of print]

2.

Transition from Leigh syndrome to MELAS syndrome in a patient with heteroplasmic MT-ND3 m.10158T>C.

Kori A, Hori I, Tanaka T, Aoyama K, Ito K, Hattori A, Ban K, Okazaki Y, Murayama K, Saitoh S.

Brain Dev. 2019 Jun 6. pii: S0387-7604(19)30117-2. doi: 10.1016/j.braindev.2019.05.006. [Epub ahead of print]

PMID:
31178082
3.

Interleukin-12p40 variant form reduces Interleukin-12p80 secretion.

Oshikiri Y, Nara H, Takeda Y, Araki A, Nemoto N, Gazi MY, Saito S, Saitoh S, Nakajima O, Asao H.

Cytokine. 2019 Aug;120:251-257. doi: 10.1016/j.cyto.2019.05.017. Epub 2019 May 27.

PMID:
31146247
4.

Annual change in plasma xanthine oxidoreductase activity is associated with changes in liver enzymes and body weight.

Furuhashi M, Koyama M, Matsumoto M, Murase T, Nakamura T, Higashiura Y, Tanaka M, Moniwa N, Ohnishi H, Saitoh S, Shimamoto K, Miura T.

Endocr J. 2019 May 25. doi: 10.1507/endocrj.EJ19-0053. [Epub ahead of print]

5.

Microglia suppress the secondary progression of autoimmune encephalomyelitis.

Tanabe S, Saitoh S, Miyajima H, Itokazu T, Yamashita T.

Glia. 2019 May 20. doi: 10.1002/glia.23640. [Epub ahead of print]

PMID:
31106910
6.

Telomerase Plays a Pivotal Role in Collateral Growth Under Ischemia by Suppressing Age-Induced Oxidative Stress, Expression of p53, and Pro-Apoptotic Proteins.

Kokubun T, Saitoh SI, Miura S, Ishida T, Takeishi Y.

Int Heart J. 2019 May 30;60(3):736-745. doi: 10.1536/ihj.18-564. Epub 2019 May 17.

7.

Author Correction: A missense mutation in the HECT domain of NEDD4L identified in a girl with periventricular nodular heterotopia, polymicrogyria, and cleft palate.

Kato K, Miya F, Hori I, Ieda D, Ohashi K, Negishi Y, Hattori A, Okamoto N, Kato M, Tsunoda T, Yamasaki M, Kanemura Y, Kosaki K, Saitoh S.

J Hum Genet. 2019 Apr 26. doi: 10.1038/s10038-019-0610-8. [Epub ahead of print]

PMID:
31028281
8.

JSH Statement: Asahikawa declaration in promotion of diversity by the Japanese society of hypertension-the JSH Asahikawa declaration.

Nakamura S, Hasebe N, Yatabe M, Kishi T, Ishida M, Ichihara A, Node K, Ishimitsu T, Itoh H, Ito M, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nishiyama A, Higaki J, Miura K, Rakugi H, Kawano Y, Tamura K, Yatabe T, Ohya Y, Ito S.

Hypertens Res. 2019 Apr 8. doi: 10.1038/s41440-019-0261-3. [Epub ahead of print] No abstract available.

PMID:
30962519
9.

The effects of renin-angiotensin system inhibitors on mortality, cardiovascular events, and renal events in hypertensive patients with diabetes: a systematic review and meta-analysis of randomized controlled trials.

Kunimura A, Himuro N, Fujiyoshi A, Segawa H, Ohnishi H, Saitoh S.

Hypertens Res. 2019 May;42(5):669-680. doi: 10.1038/s41440-019-0234-6. Epub 2019 Apr 5.

PMID:
30948835
10.

A novel splicing mutation in SLC9A6 in a boy with Christianson syndrome.

Ieda D, Hori I, Nakamura Y, Ohashi K, Negishi Y, Hattori A, Arisaka A, Hasegawa S, Saitoh S.

Hum Genome Var. 2019 Mar 25;6:15. doi: 10.1038/s41439-019-0046-x. eCollection 2019.

11.

Visual function scale for identification of infants with low respiratory compliance.

Harada E, Kinoshita M, Iwata S, Saikusa M, Tsuda K, Shindou R, Sahashi T, Kato S, Yamada Y, Saitoh S, Iwata O.

Pediatr Neonatol. 2019 Mar 2. pii: S1875-9572(18)30607-7. doi: 10.1016/j.pedneo.2019.02.006. [Epub ahead of print]

12.

Chronological dynamic changes in cortico-subcortical imbalance of cerebral blood flow in a boy with CAPOS syndrome.

Hashimoto A, Kuki I, Fukuoka M, Kim K, Inoue T, Nukui M, Okazaki S, Kawawaki H, Nakamura Y, Saitoh S.

Brain Dev. 2019 Mar 20. pii: S0387-7604(18)30525-4. doi: 10.1016/j.braindev.2019.03.003. [Epub ahead of print]

PMID:
30904181
13.

Initial- and re-treatment effectiveness of glecaprevir and pibrentasvir for Japanese patients with chronic hepatitis C virus-genotype 1/2/3 infections.

Sezaki H, Suzuki F, Hosaka T, Fujiyama S, Kawamura Y, Akuta N, Kobayashi M, Suzuki Y, Saitoh S, Arase Y, Ikeda K, Kobayashi M, Kumada H.

J Gastroenterol. 2019 Mar 22. doi: 10.1007/s00535-019-01575-9. [Epub ahead of print]

PMID:
30903385
14.

The Lack of Hepatocyte Steatosis in Adult-onset Type II Citrullinemia Patients as Assessed by 7-year Interval Paired Biopsies.

Suzuki H, Kawamura Y, Kinowaki K, Akuta N, Kasuya K, Fujiyama S, Sezaki H, Hosaka T, Saitoh S, Kobayashi M, Kobayashi M, Arase Y, Ikeda K, Suzuki F, Suzuki Y, Kumada H.

Intern Med. 2019 Feb 25. doi: 10.2169/internalmedicine.2374-18. [Epub ahead of print]

15.

Lifetime Risk of Stroke and Coronary Heart Disease Deaths According to Blood Pressure Level: EPOCH-JAPAN (Evidence for Cardiovascular Prevention From Observational Cohorts in Japan)

Satoh M, Ohkubo T, Asayama K, Murakami Y, Sugiyama D, Yamada M, Saitoh S, Sakata K, Irie F, Sairenchi T, Ishikawa S, Kiyama M, Ohnishi H, Miura K, Imai Y, Ueshima H, Okamura T; EPOCH-JAPAN Research Group.

Hypertension. 2019 Jan;73(1):52-59. doi: 10.1161/HYPERTENSIONAHA.118.11635. Epub 2018 Nov 19.

PMID:
30763510
16.

ADP-ribosylation factor-like 8b is required for the development of mouse models of systemic lupus erythematosus.

Saitoh SI, Saitoh YM, Kontani K, Sato K, Miyake K.

Int Immunol. 2019 Mar 28;31(4):225-237. doi: 10.1093/intimm/dxy084.

PMID:
30753473
17.

Intrauterine growth and the maturation process of adrenal function.

Iwata S, Kinoshita M, Okamura H, Tsuda K, Saikusa M, Harada E, Saitoh S, Iwata O.

PeerJ. 2019 Feb 7;7:e6368. doi: 10.7717/peerj.6368. eCollection 2019.

18.
19.

Endometriosis and Recurrent Pregnancy Loss as New Risk Factors for Venous Thromboembolism during Pregnancy and Post-Partum: The JECS Birth Cohort.

Sugiura-Ogasawara M, Ebara T, Matsuki T, Yamada Y, Omori T, Matsumoto Y, Kato S, Kano H, Kurihara T, Saitoh S, Kamijima M; and the Japan Environment & Children's Study (JECS) Group.

Thromb Haemost. 2019 Apr;119(4):606-617. doi: 10.1055/s-0039-1677733. Epub 2019 Feb 5.

20.

A case of early-onset epileptic encephalopathy with a homozygous TBC1D24 variant caused by uniparental isodisomy.

Nakashima M, Negishi Y, Hori I, Hattori A, Saitoh S, Saitsu H.

Am J Med Genet A. 2019 Apr;179(4):645-649. doi: 10.1002/ajmg.a.61056. Epub 2019 Jan 24.

PMID:
30680869
21.

Impact of hepatitis B core-related antigen on the incidence of hepatocellular carcinoma in patients treated with nucleos(t)ide analogues.

Hosaka T, Suzuki F, Kobayashi M, Fujiyama S, Kawamura Y, Sezaki H, Akuta N, Suzuki Y, Saitoh S, Arase Y, Ikeda K, Kobayashi M, Kumada H.

Aliment Pharmacol Ther. 2019 Feb;49(4):457-471. doi: 10.1111/apt.15108. Epub 2019 Jan 20.

PMID:
30663078
22.

JSH Statement: Kyoto declaration on hypertension research in Asia.

Ito M, Ishimitsu T, Ichihara A, Itoh H, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nakamura S, Nishiyama A, Node K, Hasebe N, Higaki J, Miura K, Rakugi H, Tamura K, Kawano Y, Yatabe T, Ohya Y, Ito S.

Hypertens Res. 2019 Jun;42(6):759-760. doi: 10.1038/s41440-018-0172-8. Epub 2019 Jan 7. No abstract available.

PMID:
30617311
23.

Impact of sodium glucose cotransporter 2 inhibitor on histological features and glucose metabolism of non-alcoholic fatty liver disease complicated by diabetes mellitus.

Akuta N, Kawamura Y, Watanabe C, Nishimura A, Okubo M, Mori Y, Fujiyama S, Sezaki H, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Suzuki F, Suzuki Y, Arase Y, Ikeda K, Kumada H.

Hepatol Res. 2019 May;49(5):531-539. doi: 10.1111/hepr.13304. Epub 2019 Feb 6.

PMID:
30577089
24.

MYCN de novo gain-of-function mutation in a patient with a novel megalencephaly syndrome.

Kato K, Miya F, Hamada N, Negishi Y, Narumi-Kishimoto Y, Ozawa H, Ito H, Hori I, Hattori A, Okamoto N, Kato M, Tsunoda T, Kanemura Y, Kosaki K, Takahashi Y, Nagata KI, Saitoh S.

J Med Genet. 2019 Jun;56(6):388-395. doi: 10.1136/jmedgenet-2018-105487. Epub 2018 Dec 20.

PMID:
30573562
25.

Interlaboratory comparison about feasibility of insoluble particulate matter test for injections with reduced test volume in light obscuration method.

Harazono A, Shibata H, Kiyoshi M, Muto T, Fukuda J, Torisu T, Saitoh S, Nishimura H, Uchiyama S, Ishii-Watabe A.

Biologicals. 2019 Jan;57:46-49. doi: 10.1016/j.biologicals.2018.12.003. Epub 2018 Dec 13.

26.

Primary liver carcinoma with sarcomatous changes: Analysis of 10 cases.

Ohya K, Saitoh S, Fujiyama S, Kawamura Y, Sezaki H, Hosaka T, Akuta N, Kobayashi M, Kobayashi M, Suzuki F, Suzuki Y, Arase Y, Ikeda K, Kinowaki K, Fujii T, Kondo F, Kumada H.

Hepatol Res. 2018 Dec 7. doi: 10.1111/hepr.13295. [Epub ahead of print]

PMID:
30537443
27.

Cytidine deaminase enables Toll-like receptor 8 activation by cytidine or its analogs.

Furusho K, Shibata T, Sato R, Fukui R, Motoi Y, Zhang Y, Saitoh SI, Ichinohe T, Moriyama M, Nakamura S, Miyake K.

Int Immunol. 2018 Dec 10. doi: 10.1093/intimm/dxy075. [Epub ahead of print]

PMID:
30535046
28.

A subanalysis of Japanese patients in a randomized, double-blind, placebo-controlled, phase 3 trial of nivolumab for patients with advanced gastric or gastro-esophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2).

Kato K, Satoh T, Muro K, Yoshikawa T, Tamura T, Hamamoto Y, Chin K, Minashi K, Tsuda M, Yamaguchi K, Machida N, Esaki T, Goto M, Komatsu Y, Nakajima TE, Sugimoto N, Yoshida K, Oki E, Nishina T, Tsuji A, Fujii H, Kunieda K, Saitoh S, Omuro Y, Azuma M, Iwamoto Y, Taku K, Fushida S, Chen LT, Kang YK, Boku N.

Gastric Cancer. 2019 Mar;22(2):344-354. doi: 10.1007/s10120-018-0899-6. Epub 2018 Dec 1.

29.

[The Identification of Critical Quality Attributes (CQAs) for the Development of Antibody Drugs].

Saitoh S.

Yakugaku Zasshi. 2018;138(12):1475-1481. doi: 10.1248/yakushi.18-00020-1. Review. Japanese.

30.

Independent links between plasma xanthine oxidoreductase activity and levels of adipokines.

Furuhashi M, Matsumoto M, Murase T, Nakamura T, Higashiura Y, Koyama M, Tanaka M, Moniwa N, Ohnishi H, Saitoh S, Shimamoto K, Miura T.

J Diabetes Investig. 2018 Dec 5. doi: 10.1111/jdi.12982. [Epub ahead of print]

31.

Effectiveness of Particle Radiotherapy in Various Stages of Hepatocellular Carcinoma: A Pilot Study.

Sorin Y, Ikeda K, Kawamura Y, Fujiyama S, Kobayashi M, Hosaka T, Sezaki H, Akuta N, Saitoh S, Suzuki F, Suzuki Y, Arase Y, Kumada H.

Liver Cancer. 2018 Oct;7(4):323-334. doi: 10.1159/000487311. Epub 2018 Mar 14.

32.

Adverse pregnancy and perinatal outcome in patients with recurrent pregnancy loss: Multiple imputation analyses with propensity score adjustment applied to a large-scale birth cohort of the Japan Environment and Children's Study.

Sugiura-Ogasawara M, Ebara T, Yamada Y, Shoji N, Matsuki T, Kano H, Kurihara T, Omori T, Tomizawa M, Miyata M, Kamijima M, Saitoh S; Japan Environment, Children’s Study (JECS) Group.

Am J Reprod Immunol. 2019 Jan;81(1):e13072. doi: 10.1111/aji.13072. Epub 2018 Dec 13.

PMID:
30430678
33.

Hepatocellular carcinoma is the most common liver-related complication in patients with histopathologically-confirmed NAFLD in Japan.

Akuta N, Kawamura Y, Arase Y, Saitoh S, Fujiyama S, Sezaki H, Hosaka T, Kobayashi M, Kobayashi M, Suzuki Y, Suzuki F, Ikeda K, Kumada H.

BMC Gastroenterol. 2018 Nov 6;18(1):165. doi: 10.1186/s12876-018-0900-1.

34.

Complex Association of Virus- and Host-Related Factors with Hepatocellular Carcinoma Rate following Hepatitis C Virus Clearance.

Akuta N, Suzuki F, Sezaki H, Kobayashi M, Fujiyama S, Kawamura Y, Hosaka T, Kobayashi M, Saitoh S, Suzuki Y, Arase Y, Ikeda K, Kumada H.

J Clin Microbiol. 2019 Jan 2;57(1). pii: e01463-18. doi: 10.1128/JCM.01463-18. Print 2019 Jan.

PMID:
30381417
35.

Development of a T-cell receptor multimer with high avidity for detecting a naturally presented tumor-associated antigen on osteosarcoma cells.

Watanabe K, Tsukahara T, Toji S, Saitoh S, Hirohashi Y, Nakatsugawa M, Kubo T, Kanaseki T, Kameshima H, Terui T, Sato N, Torigoe T.

Cancer Sci. 2019 Jan;110(1):40-51. doi: 10.1111/cas.13854. Epub 2018 Dec 1.

36.

The Japanese Society of Hypertension-Digest of plan for the future.

Node K, Kishi T, Tanaka A, Itoh H, Rakugi H, Ohya Y, Miura K, Okamura T, Ishimitsu T, Ichihara A, Ito M, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nakamura S, Nishiyama A, Hasebe N, Higaki J, Tamura K, Kawano Y, Yatabe T, Ito S; JSH Future Plan Working Group and Executive Board Members.

Hypertens Res. 2018 Dec;41(12):989-990. doi: 10.1038/s41440-018-0111-8. Epub 2018 Oct 11. No abstract available.

PMID:
30310169
37.

Neuromuscular electrical stimulation increases serum brain-derived neurotrophic factor in humans.

Kimura T, Kaneko F, Iwamoto E, Saitoh S, Yamada T.

Exp Brain Res. 2019 Jan;237(1):47-56. doi: 10.1007/s00221-018-5396-y. Epub 2018 Oct 10.

PMID:
30306243
38.

No-touch ablation in hepatocellular carcinoma has the potential to prevent intrasubsegmental recurrence to the same degree as surgical resection.

Kawamura Y, Ikeda K, Shindoh J, Kobayashi Y, Kasuya K, Fujiyama S, Hosaka T, Kobayashi M, Saitoh S, Sezaki H, Akuta N, Suzuki F, Suzuki Y, Arase Y, Hashimoto M, Kumada H.

Hepatol Res. 2019 Feb;49(2):164-176. doi: 10.1111/hepr.13254. Epub 2018 Nov 6.

PMID:
30277295
39.

Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis.

Sato R, Kato A, Chimura T, Saitoh SI, Shibata T, Murakami Y, Fukui R, Liu K, Zhang Y, Arii J, Sun-Wada GH, Wada Y, Ikenoue T, Barber GN, Manabe T, Kawaguchi Y, Miyake K.

Nat Immunol. 2018 Oct;19(10):1071-1082. doi: 10.1038/s41590-018-0203-2. Epub 2018 Sep 10.

PMID:
30201994
40.

Extracellular glucose level regulates dependence on GRP78 for cell surface localization of multipass transmembrane proteins in HeLa cells.

Toyoda Y, Akarlar B, Sarov M, Ozlu N, Saitoh S.

FEBS Lett. 2018 Oct;592(19):3295-3304. doi: 10.1002/1873-3468.13232. Epub 2018 Sep 8.

PMID:
30156266
41.

Long-term outcome of entecavir treatment of nucleos(t)ide analogue-naïve chronic hepatitis B patients in Japan.

Suzuki F, Hosaka T, Suzuki Y, Sezaki H, Akuta N, Fujiyama S, Kawamura Y, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Kobayashi M, Mineta R, Suzuki Y, Kumada H.

J Gastroenterol. 2019 Feb;54(2):182-193. doi: 10.1007/s00535-018-1502-y. Epub 2018 Aug 22.

PMID:
30136216
42.

Associations of High-Density Lipoprotein Particle and High-Density Lipoprotein Cholesterol With Alcohol Intake, Smoking, and Body Mass Index - The INTERLIPID Study.

Zaid M, Miura K, Okayama A, Nakagawa H, Sakata K, Saitoh S, Okuda N, Yoshita K, Choudhury SR, Rodriguez B, Masaki K, Willcox B, Miyagawa N, Okamura T, Chan Q, Elliott P, Stamler J, Ueshima H; INTERLIPID and INTERMAP Research Groups.

Circ J. 2018 Sep 25;82(10):2557-2565. doi: 10.1253/circj.CJ-18-0341. Epub 2018 Aug 21.

43.

Efficacy and safety of elbasvir plus grazoprevir combination therapy in Japanese patients infected with hepatitis C virus genotype 1b.

Takeuchi Y, Akuta N, Sezaki H, Suzuki F, Fujiyama S, Kawamura Y, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Suzuki Y, Arase Y, Ikeda K, Kumada H.

Hepatol Res. 2019 Mar;49(3):256-263. doi: 10.1111/hepr.13242. Epub 2018 Sep 23.

PMID:
30125438
44.

Collaborative Study for Analysis of Subvisible Particles Using Flow Imaging and Light Obscuration: Experiences in Japanese Biopharmaceutical Consortium.

Kiyoshi M, Shibata H, Harazono A, Torisu T, Maruno T, Akimaru M, Asano Y, Hirokawa M, Ikemoto K, Itakura Y, Iwura T, Kikitsu A, Kumagai T, Mori N, Murase H, Nishimura H, Oda A, Ogawa T, Ojima T, Okabe S, Saito S, Saitoh S, Suetomo H, Takegami K, Takeuchi M, Yasukawa H, Uchiyama S, Ishii-Watabe A.

J Pharm Sci. 2019 Feb;108(2):832-841. doi: 10.1016/j.xphs.2018.08.006. Epub 2018 Aug 16.

45.

A case of early colorectal cancer with rectal varices treated with endoscopic variceal ligation.

Ishiyama S, Shiode J, Yoshioka M, Nasu J, Fujiwara A, Itoh M, Fujii M, Saitoh S, Kanetoh M, Oka H.

Clin J Gastroenterol. 2019 Feb;12(1):10-14. doi: 10.1007/s12328-018-0893-x. Epub 2018 Aug 14.

PMID:
30109571
46.

Favorable efficacy of glecaprevir plus pibrentasvir as salvage therapy for HCV failures to prior direct-acting antivirals regimens.

Akuta N, Sezaki H, Suzuki F, Fujiyama S, Kawamura Y, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Suzuki Y, Arase Y, Ikeda K, Kumada H.

J Med Virol. 2019 Jan;91(1):102-106. doi: 10.1002/jmv.25278. Epub 2018 Sep 3.

PMID:
30091810
47.

Estimation of elevated intracranial pressure in infants with hydroce-phalus by using transcranial Doppler velocimetry with fontanel compression.

Yoshizuka T, Kinoshita M, Iwata S, Tsuda K, Kato T, Saikusa M, Shindou R, Hara N, Harada E, Takashima S, Takeshige N, Saitoh S, Yamashita Y, Iwata O.

Sci Rep. 2018 Aug 7;8(1):11824. doi: 10.1038/s41598-018-30274-3.

48.

Feeding-Induced Cortisol Response in Newborn Infants.

Kinoshita M, Iwata S, Okamura H, Tsuda K, Saikusa M, Harada E, Yamashita Y, Saitoh S, Iwata O.

J Clin Endocrinol Metab. 2018 Dec 1;103(12):4450-4455. doi: 10.1210/jc.2018-01052.

PMID:
30085188
49.

The putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast.

Nakazawa N, Teruya T, Sajiki K, Kumada K, Villar-Briones A, Arakawa O, Takada J, Saitoh S, Yanagida M.

J Cell Sci. 2018 Aug 21;131(16). pii: jcs217331. doi: 10.1242/jcs.217331.

50.

Unexpected high plasma xanthine oxidoreductase activity in female subjects with low levels of uric acid.

Furuhashi M, Mori K, Tanaka M, Maeda T, Matsumoto M, Murase T, Nakamura T, Koyama M, Moniwa N, Ohnishi H, Saitoh S, Shimamoto K, Miura T.

Endocr J. 2018 Nov 29;65(11):1083-1092. doi: 10.1507/endocrj.EJ18-0127. Epub 2018 Aug 2.

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