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Items: 1 to 50 of 1330

1.

Early phase 2 trial of TAS-205 in patients with Duchenne muscular dystrophy.

Komaki H, Maegaki Y, Matsumura T, Shiraishi K, Awano H, Nakamura A, Kinoshita S, Ogata K, Ishigaki K, Saitoh S, Funato M, Kuru S, Nakayama T, Iwata Y, Yajima H, Takeda S.

Ann Clin Transl Neurol. 2020 Jan 20. doi: 10.1002/acn3.50978. [Epub ahead of print]

2.

Influence of Percutaneous Occlusion of Atrial Septal Defect on Left Atrial Function Evaluated Using 2D Speckle Tracking Echocardiography.

Suzuki K, Kato T, Koyama S, Shinohara T, Inukai S, Sato J, Yamamoto H, Omori D, Yoshida S, Takeda S, Nishikawa H, Ohashi N, Sakurai H, Saitoh S.

Int Heart J. 2020 Jan 17. doi: 10.1536/ihj.19-173. [Epub ahead of print]

3.

Recent achievements and current interests in research on the characterization and quality control of biopharmaceuticals in Japan.

Ishii-Watabe A, Shibata H, Suetomo H, Ikeda Y, Telikepalli S, Kiyoshi M, Hayashi Y, Muto T, Tanaka Y, Ueda S, Iwura T, Saitoh S, Aoyama M, Harazono A, Hyuga M, Goda Y, Torisu T, Uchiyama S.

J Pharm Sci. 2020 Jan 9. pii: S0022-3549(20)30006-X. doi: 10.1016/j.xphs.2020.01.001. [Epub ahead of print]

PMID:
31927040
4.

Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7.

Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.

Commun Biol. 2019 Jul 24;2(1):270. doi: 10.1038/s42003-019-0503-6.

PMID:
31925092
5.

Differential regulation of hypoxanthine and xanthine by obesity in a general population.

Furuhashi M, Koyama M, Higashiura Y, Murase T, Nakamura T, Matsumoto M, Sakai A, Ohnishi H, Tanaka M, Saitoh S, Moniwa N, Shimamoto K, Miura T.

J Diabetes Investig. 2020 Jan 8. doi: 10.1111/jdi.13207. [Epub ahead of print]

6.

Circulating MicroRNA-122 and Fibrosis Stage Predict Mortality of Japanese Patients With Histopathologically Confirmed NAFLD.

Akuta N, Kawamura Y, Arase Y, Saitoh S, Fujiyama S, Sezaki H, Hosaka T, Kobayashi M, Kobayashi M, Suzuki Y, Suzuki F, Ikeda K, Kumada H.

Hepatol Commun. 2019 Nov 5;4(1):66-76. doi: 10.1002/hep4.1445. eCollection 2020 Jan.

7.

Novel compound heterozygous MCOLN1 mutations identified in a Japanese girl with severe developmental delay and thin corpus callosum.

Yamaguchi N, Ban K, Suzuki A, Nakamura Y, Kato K, Muramatsu H, Okuno Y, Hattori A, Kaname T, Takahashi Y, Saitoh S.

Brain Dev. 2019 Dec 31. pii: S0387-7604(19)30709-0. doi: 10.1016/j.braindev.2019.12.003. [Epub ahead of print]

PMID:
31899079
8.

Successful treatment of adult-onset type II citrullinemia with a low-carbohydrate diet and L-arginine after DNA analysis produced a definitive diagnosis.

Unita S, Hirashima N, Shimada M, Tsunekawa T, Tanaka D, Kondo T, Urata N, Kondo H, Saito M, Iwase H, Ito S, Togawa T, Saitoh S, Tanaka Y.

Clin J Gastroenterol. 2020 Jan 2. doi: 10.1007/s12328-019-01083-6. [Epub ahead of print]

PMID:
31898207
9.

Respiratory illness and acute flaccid myelitis in the Tokai district in 2018.

Okumura A, Numoto S, Iwayama H, Kurahashi H, Natsume J, Saitoh S, Yoshikawa T, Fukao T, Hirayama M, Takahashi Y; Aichi Pediatric Clinical Study Group.

Pediatr Int. 2019 Dec 30. doi: 10.1111/ped.14128. [Epub ahead of print]

PMID:
31886594
10.

Reliability and validity of a Japanese version of the psychosocial assessment tool for families of children with cancer.

Tsumura A, Okuyama T, Ito Y, Kondo M, Saitoh S, Kamei M, Sato I, Ishida Y, Kato Y, Takeda Y, Akechi T.

Jpn J Clin Oncol. 2019 Dec 13. pii: hyz181. doi: 10.1093/jjco/hyz181. [Epub ahead of print]

PMID:
31836884
11.

Echovirus Type 7 Virus-Associated Hemophagocytic Syndrome in a Neonate Successfully Treated With Intravenous Immunoglobulin Therapy: A Case Report.

Watanabe Y, Sugiura T, Sugimoto M, Togawa Y, Kouwaki M, Koyama N, Saitoh S.

Front Pediatr. 2019 Nov 14;7:469. doi: 10.3389/fped.2019.00469. eCollection 2019.

12.

Schaaf-Yang syndrome shows a Prader-Willi syndrome-like phenotype during infancy.

Negishi Y, Ieda D, Hori I, Nozaki Y, Yamagata T, Komaki H, Tohyama J, Nagasaki K, Tada H, Saitoh S.

Orphanet J Rare Dis. 2019 Dec 2;14(1):277. doi: 10.1186/s13023-019-1249-4.

13.

Advantage of liver stiffness measurement before and after direct-acting antiviral therapy to predict hepatocellular carcinoma and exacerbation of esophageal varices in chronic hepatitis C.

Ogasawara N, Saitoh S, Akuta N, Sezaki H, Suzuki F, Fujiyama S, Kawamura Y, Hosaka T, Kobayashi M, Suzuki Y, Arase Y, Ikeda K, Kumada H.

Hepatol Res. 2019 Nov 30. doi: 10.1111/hepr.13467. [Epub ahead of print]

PMID:
31785120
14.

An elderly man with progressive focal nodular hyperplasia.

Hamada K, Saitoh S, Nishino N, Fukushima D, Techigawara K, Koyanagi R, Horikawa Y, Shiwa Y, Sakuma H, Kondo F.

Clin J Gastroenterol. 2019 Nov 25. doi: 10.1007/s12328-019-01072-9. [Epub ahead of print]

PMID:
31768882
15.

Exposure levels of organophosphate pesticides in Japanese diapered children: Contributions of exposure-related behaviors and mothers' considerations of food selection and preparation.

Oya N, Ito Y, Ebara T, Kato S, Hioki K, Aoi A, Ueyama J, Oguri T, Shoji N, Sugiura-Ogasawara M, Saitoh S, Kamijima M.

Environ Int. 2020 Jan;134:105294. doi: 10.1016/j.envint.2019.105294. Epub 2019 Nov 12.

16.

Cohort profile: Aichi regional sub-cohort of the Japan Environment and Children's Study (JECS-A).

Ebara T, Yamada Y, Shoji N, Ito Y, Nakagawa A, Miyachi T, Ozaki Y, Omori T, Suzuki S, Kojima M, Ueyama J, Tomizawa M, Kato S, Oguri T, Matsuki T, Sato H, Oya N, Sugiura-Ogasawara M, Saitoh S, Kamijima M.

BMJ Open. 2019 Nov 12;9(11):e028105. doi: 10.1136/bmjopen-2018-028105.

17.

Biallelic VPS35L pathogenic variants cause 3C/Ritscher-Schinzel-like syndrome through dysfunction of retriever complex.

Kato K, Oka Y, Muramatsu H, Vasilev FF, Otomo T, Oishi H, Kawano Y, Kidokoro H, Nakazawa Y, Ogi T, Takahashi Y, Saitoh S.

J Med Genet. 2019 Nov 11. pii: jmedgenet-2019-106213. doi: 10.1136/jmedgenet-2019-106213. [Epub ahead of print]

PMID:
31712251
18.

Lower limb muscle mass is associated with insulin resistance more than lower limb muscle strength in non-diabetic older adults.

Seko T, Akasaka H, Koyama M, Himuro N, Saitoh S, Miura T, Mori M, Ohnishi H.

Geriatr Gerontol Int. 2019 Dec;19(12):1254-1259. doi: 10.1111/ggi.13805. Epub 2019 Oct 31.

PMID:
31674127
19.

Attitudes of school teachers toward epilepsy in Nagoya, Japan.

Okumura A, Saitoh S, Natsume J, Yamamoto H, Kurahashi H, Numoto S.

Epilepsy Behav. 2019 Oct 23:106359. doi: 10.1016/j.yebeh.2019.06.005. [Epub ahead of print]

PMID:
31668579
20.

Effects of long working hours and shift work during pregnancy on obstetric and perinatal outcomes: A large prospective cohort study-Japan Environment and Children's Study.

Suzumori N, Ebara T, Matsuki T, Yamada Y, Kato S, Omori T, Saitoh S, Kamijima M, Sugiura-Ogasawara M; Japan Environment & Children’s Study Group.

Birth. 2019 Oct 31. doi: 10.1111/birt.12463. [Epub ahead of print]

PMID:
31667913
21.

A novel CUL4B splice site variant in a young male exhibiting less pronounced features.

Nakamura Y, Okuno Y, Muramatsu H, Kawai T, Satou K, Ieda D, Hori I, Ohashi K, Negishi Y, Hattori A, Takahashi Y, Kojima S, Saitoh S.

Hum Genome Var. 2019 Sep 4;6:43. doi: 10.1038/s41439-019-0074-6. eCollection 2019.

22.

Poorly Differentiated Hepatocellular Carcinoma in a Low-risk Patient with an Otherwise Normal Liver.

Ogasawara N, Saitoh S, Denpou H, Kinowaki K, Akuta N, Suzuki F, Hashimoto M, Fujiyama S, Kawamura Y, Sezaki H, Hosaka T, Kobayashi M, Suzuki Y, Arase Y, Ikeda K, Fujii T, Kumada H.

Intern Med. 2019 Oct 17. doi: 10.2169/internalmedicine.3577-19. [Epub ahead of print]

23.

Predictors of Insulin Secretion in Japanese Patients with Histopathologically-confirmed Non-alcoholic Fatty Liver Disease.

Akuta N, Kawamura Y, Fujiyama S, Sezaki H, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Suzuki F, Suzuki Y, Arase Y, Ikeda K, Kumada H.

Intern Med. 2019 Sep 18. doi: 10.2169/internalmedicine.3555-19. [Epub ahead of print]

24.

Identification of 15 New Bypassable Essential Genes of Fission Yeast.

Takeda A, Saitoh S, Ohkura H, Sawin KE, Goshima G.

Cell Struct Funct. 2019 Sep 27;44(2):113-119. doi: 10.1247/csf.19025. Epub 2019 Aug 31. Erratum in: Cell Struct Funct. 2019;44(2):171.

25.

De novo variants in SETD1B cause intellectual disability, autism spectrum disorder, and epilepsy with myoclonic absences.

Hiraide T, Hattori A, Ieda D, Hori I, Saitoh S, Nakashima M, Saitsu H.

Epilepsia Open. 2019 May 24;4(3):476-481. doi: 10.1002/epi4.12339. eCollection 2019 Sep.

26.

Constitutive activation of mTORC1 signaling induced by biallelic loss-of-function mutations in SZT2 underlies a discernible neurodevelopmental disease.

Nakamura Y, Kato K, Tsuchida N, Matsumoto N, Takahashi Y, Saitoh S.

PLoS One. 2019 Aug 20;14(8):e0221482. doi: 10.1371/journal.pone.0221482. eCollection 2019.

27.

The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019).

Umemura S, Arima H, Arima S, Asayama K, Dohi Y, Hirooka Y, Horio T, Hoshide S, Ikeda S, Ishimitsu T, Ito M, Ito S, Iwashima Y, Kai H, Kamide K, Kanno Y, Kashihara N, Kawano Y, Kikuchi T, Kitamura K, Kitazono T, Kohara K, Kudo M, Kumagai H, Matsumura K, Matsuura H, Miura K, Mukoyama M, Nakamura S, Ohkubo T, Ohya Y, Okura T, Rakugi H, Saitoh S, Shibata H, Shimosawa T, Suzuki H, Takahashi S, Tamura K, Tomiyama H, Tsuchihashi T, Ueda S, Uehara Y, Urata H, Hirawa N.

Hypertens Res. 2019 Sep;42(9):1235-1481. doi: 10.1038/s41440-019-0284-9. Review. No abstract available.

PMID:
31375757
28.

Long-term outcome of hepatocellular carcinoma occurrence, esophageal varices exacerbation, and mortality in hepatitis C virus-related liver cirrhosis after interferon-based therapy.

Ogasawara N, Saitoh S, Akuta N, Fujiyama S, Kawamura Y, Sezaki H, Hosaka T, Kobayashi M, Suzuki F, Suzuki Y, Arase Y, Ikeda K, Kumada H.

Hepatol Res. 2019 Dec;49(12):1441-1450. doi: 10.1111/hepr.13418. Epub 2019 Oct 9.

PMID:
31373093
29.

Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7.

Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.

Commun Biol. 2019 Jul 24;2:270. doi: 10.1038/s42003-019-0503-6. eCollection 2019.

30.

Real-world effects of long-term rifaximin treatment for Japanese patients with hepatic encephalopathy.

Suzuki H, Sezaki H, Suzuki F, Kasuya K, Sano T, Fujiyama S, Kawamura Y, Hosaka T, Akuta N, Saitoh S, Kobayashi M, Arase Y, Ikeda K, Suzuki Y, Kumada H.

Hepatol Res. 2019 Dec;49(12):1406-1413. doi: 10.1111/hepr.13415. Epub 2019 Aug 9.

PMID:
31347756
31.

Peripartum depression and infant care, sleep and growth.

Iwata S, Kinoshita M, Fujita F, Tsuda K, Unno M, Horinouchi T, Morokuma S, Saitoh S, Iwata O.

Sci Rep. 2019 Jul 15;9(1):10186. doi: 10.1038/s41598-019-46563-4.

32.

Delayed recognition of childhood arterial ischemic stroke.

Hori I, Tsuji T, Miyake M, Ueda K, Kataoka E, Suzuki M, Kobayashi S, Kurahashi H, Takahashi Y, Okumura A, Yoshikawa T, Saitoh S, Natsume J.

Pediatr Int. 2019 Sep;61(9):895-903. doi: 10.1111/ped.13966.

PMID:
31295764
33.

Efficacy of long-term rifaximin treatment for hepatic encephalopathy in the Japanese.

Nishida S, Hamada K, Nishino N, Fukushima D, Koyanagi R, Horikawa Y, Shiwa Y, Saitoh S.

World J Hepatol. 2019 Jun 27;11(6):531-541. doi: 10.4254/wjh.v11.i6.531.

34.

Insulin Resistance is Associated with Longitudinal Changes of Cardiac Repolarization Heterogeneity in Apparently Healthy Subjects.

Matsumoto T, Ohnishi H, Sato T, Miki T, Akasaka H, Hanawa N, Koyama M, Saitoh S, Miura T.

Cardiol Ther. 2019 Jul 4:239-251. doi: 10.1007/s40119-019-0140-7. [Epub ahead of print]

35.

Endolysosomal compartments as platforms for orchestrating innate immune and metabolic sensors.

Miyake K, Saitoh SI, Sato R, Shibata T, Fukui R, Murakami Y.

J Leukoc Biol. 2019 Oct;106(4):853-862. doi: 10.1002/JLB.MR0119-020R. Epub 2019 Jun 20. Review.

PMID:
31219657
36.

Role of NS5A-L31/Y93 Double Wild-type in Failure of Glecaprevir/Pibrentasvir Double Therapy in Two Patients with a History of Direct-acting Antiviral Agent Failure: An Ultra-deep Sequencing Analysis.

Sano T, Akuta N, Suzuki F, Kasuya K, Fujiyama S, Kawamura Y, Sezaki H, Hosaka T, Saitoh S, Kobayashi M, Suzuki Y, Kobayashi M, Arase Y, Ikeda K, Kumada H.

Intern Med. 2019 Sep 15;58(18):2657-2662. doi: 10.2169/internalmedicine.2604-18. Epub 2019 Jun 7.

37.

Transition from Leigh syndrome to MELAS syndrome in a patient with heteroplasmic MT-ND3 m.10158T>C.

Kori A, Hori I, Tanaka T, Aoyama K, Ito K, Hattori A, Ban K, Okazaki Y, Murayama K, Saitoh S.

Brain Dev. 2019 Oct;41(9):803-807. doi: 10.1016/j.braindev.2019.05.006. Epub 2019 Jun 6.

PMID:
31178082
38.

Interleukin-12p40 variant form reduces Interleukin-12p80 secretion.

Oshikiri Y, Nara H, Takeda Y, Araki A, Nemoto N, Gazi MY, Saito S, Saitoh S, Nakajima O, Asao H.

Cytokine. 2019 Aug;120:251-257. doi: 10.1016/j.cyto.2019.05.017. Epub 2019 May 27.

PMID:
31146247
39.

Annual change in plasma xanthine oxidoreductase activity is associated with changes in liver enzymes and body weight.

Furuhashi M, Koyama M, Matsumoto M, Murase T, Nakamura T, Higashiura Y, Tanaka M, Moniwa N, Ohnishi H, Saitoh S, Shimamoto K, Miura T.

Endocr J. 2019 Sep 28;66(9):777-786. doi: 10.1507/endocrj.EJ19-0053. Epub 2019 May 25.

40.

Microglia suppress the secondary progression of autoimmune encephalomyelitis.

Tanabe S, Saitoh S, Miyajima H, Itokazu T, Yamashita T.

Glia. 2019 Sep;67(9):1694-1704. doi: 10.1002/glia.23640. Epub 2019 May 20.

PMID:
31106910
41.

Telomerase Plays a Pivotal Role in Collateral Growth Under Ischemia by Suppressing Age-Induced Oxidative Stress, Expression of p53, and Pro-Apoptotic Proteins.

Kokubun T, Saitoh SI, Miura S, Ishida T, Takeishi Y.

Int Heart J. 2019 May 30;60(3):736-745. doi: 10.1536/ihj.18-564. Epub 2019 May 17.

42.

Author Correction: A missense mutation in the HECT domain of NEDD4L identified in a girl with periventricular nodular heterotopia, polymicrogyria, and cleft palate.

Kato K, Miya F, Hori I, Ieda D, Ohashi K, Negishi Y, Hattori A, Okamoto N, Kato M, Tsunoda T, Yamasaki M, Kanemura Y, Kosaki K, Saitoh S.

J Hum Genet. 2019 Jul;64(7):701-702. doi: 10.1038/s10038-019-0610-8.

PMID:
31028281
43.

JSH Statement: Asahikawa declaration in promotion of diversity by the Japanese society of hypertension-the JSH Asahikawa declaration.

Nakamura S, Hasebe N, Yatabe M, Kishi T, Ishida M, Ichihara A, Node K, Ishimitsu T, Itoh H, Ito M, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nishiyama A, Higaki J, Miura K, Rakugi H, Kawano Y, Tamura K, Yatabe T, Ohya Y, Ito S.

Hypertens Res. 2019 Oct;42(10):1483-1484. doi: 10.1038/s41440-019-0261-3. Epub 2019 Apr 8. No abstract available.

PMID:
30962519
44.

The effects of renin-angiotensin system inhibitors on mortality, cardiovascular events, and renal events in hypertensive patients with diabetes: a systematic review and meta-analysis of randomized controlled trials.

Kunimura A, Himuro N, Fujiyoshi A, Segawa H, Ohnishi H, Saitoh S.

Hypertens Res. 2019 May;42(5):669-680. doi: 10.1038/s41440-019-0234-6. Epub 2019 Apr 5.

PMID:
30948835
45.

A novel splicing mutation in SLC9A6 in a boy with Christianson syndrome.

Ieda D, Hori I, Nakamura Y, Ohashi K, Negishi Y, Hattori A, Arisaka A, Hasegawa S, Saitoh S.

Hum Genome Var. 2019 Mar 25;6:15. doi: 10.1038/s41439-019-0046-x. eCollection 2019.

46.

Visual function scale for identification of infants with low respiratory compliance.

Harada E, Kinoshita M, Iwata S, Saikusa M, Tsuda K, Shindou R, Sahashi T, Kato S, Yamada Y, Saitoh S, Iwata O.

Pediatr Neonatol. 2019 Dec;60(6):611-616. doi: 10.1016/j.pedneo.2019.02.006. Epub 2019 Mar 2.

47.

Chronological dynamic changes in cortico-subcortical imbalance of cerebral blood flow in a boy with CAPOS syndrome.

Hashimoto A, Kuki I, Fukuoka M, Kim K, Inoue T, Nukui M, Okazaki S, Kawawaki H, Nakamura Y, Saitoh S.

Brain Dev. 2019 Aug;41(7):625-629. doi: 10.1016/j.braindev.2019.03.003. Epub 2019 Mar 20.

PMID:
30904181
48.

Initial- and re-treatment effectiveness of glecaprevir and pibrentasvir for Japanese patients with chronic hepatitis C virus-genotype 1/2/3 infections.

Sezaki H, Suzuki F, Hosaka T, Fujiyama S, Kawamura Y, Akuta N, Kobayashi M, Suzuki Y, Saitoh S, Arase Y, Ikeda K, Kobayashi M, Kumada H.

J Gastroenterol. 2019 Oct;54(10):916-927. doi: 10.1007/s00535-019-01575-9. Epub 2019 Mar 22.

PMID:
30903385
49.

The Lack of Hepatocyte Steatosis in Adult-onset Type II Citrullinemia Patients as Assessed by 7-year Interval Paired Biopsies.

Suzuki H, Kawamura Y, Kinowaki K, Akuta N, Kasuya K, Fujiyama S, Sezaki H, Hosaka T, Saitoh S, Kobayashi M, Kobayashi M, Arase Y, Ikeda K, Suzuki F, Suzuki Y, Kumada H.

Intern Med. 2019 Jul 1;58(13):1891-1895. doi: 10.2169/internalmedicine.2374-18. Epub 2019 Feb 25.

50.

Lifetime Risk of Stroke and Coronary Heart Disease Deaths According to Blood Pressure Level: EPOCH-JAPAN (Evidence for Cardiovascular Prevention From Observational Cohorts in Japan)

Satoh M, Ohkubo T, Asayama K, Murakami Y, Sugiyama D, Yamada M, Saitoh S, Sakata K, Irie F, Sairenchi T, Ishikawa S, Kiyama M, Ohnishi H, Miura K, Imai Y, Ueshima H, Okamura T; EPOCH-JAPAN Research Group.

Hypertension. 2019 Jan;73(1):52-59. doi: 10.1161/HYPERTENSIONAHA.118.11635. Epub 2018 Nov 19.

PMID:
30763510

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