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Items: 20

1.

Optoacoustic Detection of Early Therapy-Induced Tumor Cell Death Using a Targeted Imaging Agent.

Xie B, Tomaszewski MR, Neves AA, Ros S, Hu DE, McGuire S, Mullins SR, Tice D, Sainson RCA, Bohndiek SE, Wilkinson RW, Brindle KM.

Clin Cancer Res. 2017 Nov 15;23(22):6893-6903. doi: 10.1158/1078-0432.CCR-17-1029. Epub 2017 Aug 18.

2.

Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth.

Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Harris AL, Li JL.

Oncotarget. 2017 Jun 20;8(25):40115-40131. doi: 10.18632/oncotarget.16969.

3.

Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery.

Mosely SI, Prime JE, Sainson RC, Koopmann JO, Wang DY, Greenawalt DM, Ahdesmaki MJ, Leyland R, Mullins S, Pacelli L, Marcus D, Anderton J, Watkins A, Coates Ulrichsen J, Brohawn P, Higgs BW, McCourt M, Jones H, Harper JA, Morrow M, Valge-Archer V, Stewart R, Dovedi SJ, Wilkinson RW.

Cancer Immunol Res. 2017 Jan;5(1):29-41. doi: 10.1158/2326-6066.CIR-16-0114. Epub 2016 Dec 6.

4.

Characterization and application of two RANK-specific antibodies with different biological activities.

Chypre M, Seaman J, Cordeiro OG, Willen L, Knoop KA, Buchanan A, Sainson RC, Williams IR, Yagita H, Schneider P, Mueller CG.

Immunol Lett. 2016 Mar;171:5-14. doi: 10.1016/j.imlet.2016.01.003. Epub 2016 Jan 7.

5.

Regulation of the anti-tumour immune response by cancer-associated fibroblasts.

Harper J, Sainson RC.

Semin Cancer Biol. 2014 Apr;25:69-77. doi: 10.1016/j.semcancer.2013.12.005. Epub 2014 Jan 7. Review.

PMID:
24406209
6.

Combining virotherapy and angiotherapy for the treatment of breast cancer.

Bazan-Peregrino M, Sainson RC, Carlisle RC, Thoma C, Waters RA, Arvanitis C, Harris AL, Hernandez-Alcoceba R, Seymour LW.

Cancer Gene Ther. 2013 Aug;20(8):461-8. doi: 10.1038/cgt.2013.41. Epub 2013 Jul 12.

PMID:
23846253
7.

DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo.

Li JL, Sainson RC, Oon CE, Turley H, Leek R, Sheldon H, Bridges E, Shi W, Snell C, Bowden ET, Wu H, Chowdhury PS, Russell AJ, Montgomery CP, Poulsom R, Harris AL.

Cancer Res. 2011 Sep 15;71(18):6073-83. doi: 10.1158/0008-5472.CAN-11-1704. Epub 2011 Jul 29.

8.

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes.

Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, Oon CE, Leek R, Edelmann M, Kessler B, Sainson RC, Sargent I, Li JL, Harris AL.

Blood. 2010 Sep 30;116(13):2385-94. doi: 10.1182/blood-2009-08-239228. Epub 2010 Jun 17.

PMID:
20558614
9.

Regulation of CXCR4 by the Notch ligand delta-like 4 in endothelial cells.

Williams CK, Segarra M, Sierra Mde L, Sainson RC, Tosato G, Harris AL.

Cancer Res. 2008 Mar 15;68(6):1889-95. doi: 10.1158/0008-5472.CAN-07-2181.

10.

TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype.

Sainson RC, Johnston DA, Chu HC, Holderfield MT, Nakatsu MN, Crampton SP, Davis J, Conn E, Hughes CC.

Blood. 2008 May 15;111(10):4997-5007. doi: 10.1182/blood-2007-08-108597. Epub 2008 Mar 12.

11.

Regulation of angiogenesis by homotypic and heterotypic notch signalling in endothelial cells and pericytes: from basic research to potential therapies.

Sainson RC, Harris AL.

Angiogenesis. 2008;11(1):41-51. doi: 10.1007/s10456-008-9098-0. Epub 2008 Feb 7. Review.

PMID:
18256896
12.

Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo.

Li JL, Sainson RC, Shi W, Leek R, Harrington LS, Preusser M, Biswas S, Turley H, Heikamp E, Hainfellner JA, Harris AL.

Cancer Res. 2007 Dec 1;67(23):11244-53.

13.

Anti-Dll4 therapy: can we block tumour growth by increasing angiogenesis?

Sainson RC, Harris AL.

Trends Mol Med. 2007 Sep;13(9):389-95. Epub 2007 Sep 6. Review.

PMID:
17822956
14.

Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells.

Harrington LS, Sainson RC, Williams CK, Taylor JM, Shi W, Li JL, Harris AL.

Microvasc Res. 2008 Mar;75(2):144-54. Epub 2007 Jun 29.

PMID:
17692341
15.

A conserved mechanism for steroid receptor translocation to the plasma membrane.

Pedram A, Razandi M, Sainson RC, Kim JK, Hughes CC, Levin ER.

J Biol Chem. 2007 Aug 3;282(31):22278-88. Epub 2007 May 29.

16.

Hypoxia-regulated differentiation: let's step it up a Notch.

Sainson RC, Harris AL.

Trends Mol Med. 2006 Apr;12(4):141-3. Epub 2006 Mar 2. Review.

PMID:
16513423
17.

Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis.

Sainson RC, Aoto J, Nakatsu MN, Holderfield M, Conn E, Koller E, Hughes CC.

FASEB J. 2005 Jun;19(8):1027-9. Epub 2005 Mar 17.

PMID:
15774577
18.

Diffusion limits of an in vitro thick prevascularized tissue.

Griffith CK, Miller C, Sainson RC, Calvert JW, Jeon NL, Hughes CC, George SC.

Tissue Eng. 2005 Jan-Feb;11(1-2):257-66.

PMID:
15738680
19.

VEGF(121) and VEGF(165) regulate blood vessel diameter through vascular endothelial growth factor receptor 2 in an in vitro angiogenesis model.

Nakatsu MN, Sainson RC, Pérez-del-Pulgar S, Aoto JN, Aitkenhead M, Taylor KL, Carpenter PM, Hughes CC.

Lab Invest. 2003 Dec;83(12):1873-85.

PMID:
14691306
20.

Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and Angiopoietin-1.

Nakatsu MN, Sainson RC, Aoto JN, Taylor KL, Aitkenhead M, Pérez-del-Pulgar S, Carpenter PM, Hughes CC.

Microvasc Res. 2003 Sep;66(2):102-12.

PMID:
12935768

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