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Items: 12


Analysis of live cell images: Methods, tools and opportunities.

Nketia TA, Sailem H, Rohde G, Machiraju R, Rittscher J.

Methods. 2017 Feb 15;115:65-79. doi: 10.1016/j.ymeth.2017.02.007. Epub 2017 Feb 27. Review.


Identification of clinically predictive metagenes that encode components of a network coupling cell shape to transcription by image-omics.

Sailem HZ, Bakal C.

Genome Res. 2017 Feb;27(2):196-207. doi: 10.1101/gr.202028.115. Epub 2016 Nov 18.


Proteomics profiling of interactome dynamics by colocalisation analysis (COLA).

Mardakheh FK, Sailem HZ, Kümper S, Tape CJ, McCully RR, Paul A, Anjomani-Virmouni S, Jørgensen C, Poulogiannis G, Marshall CJ, Bakal C.

Mol Biosyst. 2016 Dec 20;13(1):92-105.


Visualizing quantitative microscopy data: History and challenges.

Sailem HZ, Cooper S, Bakal C.

Crit Rev Biochem Mol Biol. 2016;51(2):96-101. doi: 10.3109/10409238.2016.1146222. Epub 2016 Feb 24. Review.


Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis.

Natrajan R, Sailem H, Mardakheh FK, Arias Garcia M, Tape CJ, Dowsett M, Bakal C, Yuan Y.

PLoS Med. 2016 Feb 16;13(2):e1001961. doi: 10.1371/journal.pmed.1001961. eCollection 2016 Feb.


Cell shape and the microenvironment regulate nuclear translocation of NF-κB in breast epithelial and tumor cells.

Sero JE, Sailem HZ, Ardy RC, Almuttaqi H, Zhang T, Bakal C.

Mol Syst Biol. 2015 Mar;11(3):790.


Visualizing cellular imaging data using PhenoPlot.

Sailem HZ, Sero JE, Bakal C.

Nat Commun. 2015 Jan 8;6:5825. doi: 10.1038/ncomms6825.


How cells explore shape space: a quantitative statistical perspective of cellular morphogenesis.

Yin Z, Sailem H, Sero J, Ardy R, Wong ST, Bakal C.

Bioessays. 2014 Dec;36(12):1195-203. doi: 10.1002/bies.201400011. Epub 2014 Sep 12.


Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity.

Sailem H, Bousgouni V, Cooper S, Bakal C.

Open Biol. 2014 Jan 22;4:130132. doi: 10.1098/rsob.130132.


Inferring signalling networks from images.

Evans L, Sailem H, Vargas PP, Bakal C.

J Microsc. 2013 Oct;252(1):1-7. doi: 10.1111/jmi.12062. Epub 2013 Jul 11. Review.


A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes.

Yin Z, Sadok A, Sailem H, McCarthy A, Xia X, Li F, Garcia MA, Evans L, Barr AR, Perrimon N, Marshall CJ, Wong ST, Bakal C.

Nat Cell Biol. 2013 Jul;15(7):860-71. doi: 10.1038/ncb2764. Epub 2013 Jun 9.


Differential RNAi screening provides insights into the rewiring of signalling networks during oxidative stress.

Garcia MA, Alvarez MS, Sailem H, Bousgouni V, Sero J, Bakal C.

Mol Biosyst. 2012 Oct;8(10):2605-13. doi: 10.1039/c2mb25092f.


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