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Items: 1 to 50 of 261

1.

Longitudinal biobanks-based study on the joint effects of infections, nutrition and hormones on risk of prostate cancer.

Lumme S, Tenkanen L, Langseth H, Gislefoss R, Hakama M, Stattin P, Hallmans G, Adlercreutz H, Saikku P, Stenman UH, Tuohimaa P, Luostarinen T, Dillner J.

Acta Oncol. 2016 Jul;55(7):839-45. doi: 10.3109/0284186X.2016.1139178. Epub 2016 Feb 15.

PMID:
26878091
2.

The effect of proatherogenic pathogens on adipose tissue transcriptome and fatty acid distribution in apolipoprotein E-deficient mice.

Hyvärinen K, Tuomainen AM, Laitinen S, Alfthan G, Salminen I, Leinonen M, Saikku P, Kovanen PT, Jauhiainen M, Pussinen PJ.

BMC Genomics. 2013 Oct 17;14:709. doi: 10.1186/1471-2164-14-709.

3.

Influenza C virus infection in military recruits--symptoms and clinical manifestation.

Kauppila J, Rönkkö E, Juvonen R, Saukkoriipi A, Saikku P, Bloigu A, Vainio O, Ziegler T.

J Med Virol. 2014 May;86(5):879-85. doi: 10.1002/jmv.23756. Epub 2013 Sep 30.

PMID:
24122799
4.

Corn mint (Mentha arvensis) extract diminishes acute Chlamydia pneumoniae infection in vitro and in vivo.

Salin O, Törmäkangas L, Leinonen M, Saario E, Hagström M, Ketola RA, Saikku P, Vuorela H, Vuorela PM.

J Agric Food Chem. 2011 Dec 28;59(24):12836-42. doi: 10.1021/jf2032473. Epub 2011 Nov 22.

PMID:
22073967
5.

Effects of coadministration of natural polyphenols with doxycycline or calcium modulators on acute Chlamydia pneumoniae infection in vitro.

Salin OP, Pohjala LL, Saikku P, Vuorela HJ, Leinonen M, Vuorela PM.

J Antibiot (Tokyo). 2011 Nov;64(11):747-52. doi: 10.1038/ja.2011.79. Epub 2011 Sep 21.

PMID:
21934693
6.

Periodontopathogen- and host-derived immune response in acute coronary syndrome.

Alfakry H, Paju S, Sinisalo J, Nieminen MS, Valtonen V, Saikku P, Leinonen M, Pussinen PJ.

Scand J Immunol. 2011 Oct;74(4):383-9. doi: 10.1111/j.1365-3083.2011.02584.x.

7.

Antibodies to Chlamydia trachomatis in serum and peritoneal fluid of women with endometriosis.

Gazvani R, Coyne L, Anttila T, Saikku P, Paavonen J, Templeton A.

Hum Fertil (Camb). 2011 Mar;14(1):64-7. doi: 10.3109/14647273.2010.548846.

PMID:
21466268
8.

The effect of proatherogenic microbes on macrophage cholesterol homeostasis in apoE-deficient mice.

Tuomainen AM, Hyvärinen K, Ehlers PI, Mervaala E, Leinonen M, Saikku P, Kovanen PT, Jauhiainen M, Pussinen PJ.

Microb Pathog. 2011 Sep;51(3):217-24. doi: 10.1016/j.micpath.2011.03.003. Epub 2011 Mar 21.

PMID:
21421042
9.

The association of body mass index, waist and hip circumference, and waist-hip ratio with Chlamydia pneumoniae IgG antibodies and high-sensitive C-reactive protein at 31 years of age in Northern Finland Birth Cohort 1966.

Lajunen T, Bloigu A, Paldanius M, Pouta A, Laitinen J, Ruokonen A, Hartikainen AL, Savolainen M, Herzig KH, Leinonen M, Saikku P, Järvelin MR.

Int J Obes (Lond). 2011 Dec;35(12):1470-8. doi: 10.1038/ijo.2011.21. Epub 2011 Mar 8.

PMID:
21386806
10.

Interleukin-6-174 G/C promoter polymorphism is associated with persistence of Chlamydia pneumoniae antibodies in young men.

Rantala A, Lajunen T, Juvonen R, Paldanius M, Silvennoinen-Kassinen S, Peitso A, Vainio O, Leinonen M, Saikku P.

Scand J Immunol. 2011 Jul;74(1):95-9. doi: 10.1111/j.1365-3083.2011.02542.x.

11.

Association of IL-6 and IL-6R gene polymorphisms with susceptibility to respiratory tract infections in young Finnish men.

Rantala A, Lajunen T, Juvonen R, Silvennoinen-Kassinen S, Peitso A, Vainio O, Saikku P, Leinonen M.

Hum Immunol. 2011 Jan;72(1):63-8. doi: 10.1016/j.humimm.2010.10.010. Epub 2010 Oct 15.

PMID:
20951753
12.

Combination treatment in Chlamydia-triggered reactive arthritis: comment on the article by Carter et al.

Lauhio A, Saikku P, Salo T, Tschesche H, Lähdevirta J, Sorsa T.

Arthritis Rheum. 2011 Jan;63(1):305-7; author reply 307-8. doi: 10.1002/art.30075. No abstract available.

13.

Elevated MMP-8 and decreased myeloperoxidase concentrations associate significantly with the risk for peripheral atherosclerosis disease and abdominal aortic aneurysm.

Pradhan-Palikhe P, Vikatmaa P, Lajunen T, Palikhe A, Lepäntalo M, Tervahartiala T, Salo T, Saikku P, Leinonen M, Pussinen PJ, Sorsa T.

Scand J Immunol. 2010 Aug;72(2):150-7. doi: 10.1111/j.1365-3083.2010.02418.x.

14.

Rapamycin can inhibit the development of Chlamydia pneumoniae, which might partly contribute to the prevention of in-stent restenosis.

Yan Y, Silvennoinen-Kassinen S, Leinonen M, Saikku P.

Cardiovasc Drugs Ther. 2010 Jun;24(3):189-95. doi: 10.1007/s10557-010-6238-8.

PMID:
20532971
15.

Quantification of Chlamydia pneumoniae in cultured human macrophages and HL cells: comparison of real-time PCR, immunofluorescence and ELISA methods.

Poikonen K, Lajunen T, Silvennoinen-Kassinen S, Leinonen M, Saikku P.

APMIS. 2010 Jan;118(1):45-8. doi: 10.1111/j.1600-0463.2009.02557.x.

PMID:
20041870
16.

Chlamydia pneumoniae infection is associated with elevated body mass index in young men.

Rantala A, Lajunen T, Juvonen R, Bloigu A, Paldanius M, Silvennoinen-Kassinen S, Peitso A, Vainio O, Leinonen M, Saikku P.

Epidemiol Infect. 2010 Sep;138(9):1267-73. doi: 10.1017/S0950268809991452. Epub 2009 Dec 17.

PMID:
20018131
17.

Low mannose-binding lectin levels and MBL2 gene polymorphisms associate with Chlamydia pneumoniae antibodies.

Rantala A, Lajunen T, Juvonen R, Bloigu A, Paldanius M, Silvennoinen-Kassinen S, Peitso A, Vainio O, Leinonen M, Saikku P.

Innate Immun. 2011 Feb;17(1):35-40. doi: 10.1177/1753425909349759. Epub 2009 Dec 7.

PMID:
19969625
18.

Chlamydia antibodies and self-reported symptoms of oligo-amenorrhea and hirsutism: a new etiologic factor in polycystic ovary syndrome?

Morin-Papunen LC, Duleba AJ, Bloigu A, Järvelin MR, Saikku P, Pouta A.

Fertil Steril. 2010 Oct;94(5):1799-804. doi: 10.1016/j.fertnstert.2009.10.021.

PMID:
19931073
19.

Effects of CD14, TLR2, TLR4, LPB, and IL-6 gene polymorphisms on Chlamydia pneumoniae growth in human macrophages in vitro.

Poikonen K, Lajunen T, Silvennoinen-Kassinen S, Leinonen M, Saikku P.

Scand J Immunol. 2009 Jul;70(1):34-9. doi: 10.1111/j.1365-3083.2009.02267.x.

20.

Serum chlamydial lipopolysaccharide as a prognostic factor for a new cardiovascular event.

Pesonen E, Tiirola T, Andsberg E, Jauhiainen M, Paldanius M, Persson K, Saikku P, Sarna S, Ohlin H, Leinonen M.

Heart Lung. 2009 May-Jun;38(3):176-81. doi: 10.1016/j.hrtlng.2008.06.001. Epub 2008 Oct 5.

PMID:
19486785
21.

Chlamydial and periodontal pathogens induce hepatic inflammation and fatty acid imbalance in apolipoprotein E-deficient mice.

Hyvärinen K, Tuomainen AM, Laitinen S, Bykov IL, Törmäkangas L, Lindros K, Käkelä R, Alfthan G, Salminen I, Jauhiainen M, Kovanen PT, Leinonen M, Saikku P, Pussinen PJ.

Infect Immun. 2009 Aug;77(8):3442-9. doi: 10.1128/IAI.00389-09. Epub 2009 May 18.

22.

Beneficial effect of clarithromycin in patients with acute coronary syndrome and complement C4 deficiencies.

Paakkanen R, Palikhe A, Seppänen M, Nieminen MS, Vauhkonen H, Saikku P, Lokki ML, Sinisalo J.

Scand Cardiovasc J. 2009 Dec;43(6):395-401. doi: 10.1080/14017430902874305.

PMID:
19365786
23.

Weight at birth and infancy in relation to adult leukocyte count: a population-based study of 5619 men and women followed from the fetal period to adulthood.

Canoy D, Pouta A, Ruokonen A, Hartikainen AL, Saikku P, Järvelin MR.

J Clin Endocrinol Metab. 2009 Jun;94(6):1916-22. doi: 10.1210/jc.2008-2545. Epub 2009 Mar 10.

PMID:
19276227
24.

Chlamydia pneumoniae DNA is present in peripheral blood mononuclear cells during acute coronary syndrome and correlates with chlamydial lipopolysaccharide levels in serum.

Palikhe A, Tiirola T, Puolakkainen M, Nieminen MS, Saikku P, Leinonen M, Sinisalo J.

Scand J Infect Dis. 2009;41(3):201-5. doi: 10.1080/00365540902737968.

PMID:
19172436
25.

Chlamydial lipopolysaccharide (cLPS) is present in atherosclerotic and aneurysmal arterial wall--cLPS levels depend on disease manifestation.

Vikatmaa P, Lajunen T, Ikonen TS, Pussinen PJ, Lepäntalo M, Leinonen M, Saikku P.

Cardiovasc Pathol. 2010 Jan-Feb;19(1):48-54. doi: 10.1016/j.carpath.2008.10.012. Epub 2009 Jan 15.

PMID:
19150246
26.

Chlamydial LPS and high-sensitivity CRP levels in serum are associated with an elevated body mass index in patients with cardiovascular disease.

Lajunen T, Vikatmaa P, Bloigu A, Ikonen T, Lepäntalo M, Pussinen PJ, Saikku P, Leinonen M.

Innate Immun. 2008 Dec;14(6):375-82. doi: 10.1177/1753425908099172.

PMID:
19039061
27.

Mannose-binding lectin concentrations, MBL2 polymorphisms, and susceptibility to respiratory tract infections in young men.

Rantala A, Lajunen T, Juvonen R, Bloigu A, Silvennoinen-Kassinen S, Peitso A, Saikku P, Vainio O, Leinonen M.

J Infect Dis. 2008 Oct 15;198(8):1247-53. doi: 10.1086/591912.

PMID:
18729778
28.

Selective cyclooxygenase inhibitors prevent the growth of Chlamydia pneumoniae in HL cells.

Yan Y, Silvennoinen-Kassinen S, Törmäkangas L, Leinonen M, Saikku P.

Int J Antimicrob Agents. 2008 Jul;32(1):78-83. doi: 10.1016/j.ijantimicag.2008.02.021. Epub 2008 Jun 4.

PMID:
18524544
29.

Risk factors for acute respiratory tract illness in military conscripts.

Juvonen R, Bloigu A, Peitso A, Silvennoinen-Kassinen S, Saikku P, Leinonen M, Harju T.

Respirology. 2008 Jun;13(4):575-80. doi: 10.1111/j.1440-1843.2008.01299.x.

PMID:
18494948
30.

Maternal serum Chlamydia pneumoniae antibodies and CRP levels in women with preeclampsia and gestational hypertension.

Karinen L, Leinonen M, Bloigu A, Paldanius M, Koskela P, Saikku P, Hartikainen AL, Jarvelin MR, Pouta A.

Hypertens Pregnancy. 2008;27(2):143-58. doi: 10.1080/10641950701885188.

PMID:
18484420
31.

Intragastric primary infection sensitizes to lung reinfection in a Chlamydia pneumoniae mouse model.

Erkkilä L, Saario E, Laitinen K, Saikku P, Leinonen M.

Vaccine. 2008 May 12;26(20):2503-9. doi: 10.1016/j.vaccine.2008.03.034. Epub 2008 Apr 3.

PMID:
18433949
32.

Training improves physical fitness and decreases CRP also in asthmatic conscripts.

Juvonen R, Bloigu A, Peitso A, Silvennoinen-Kassinen S, Saikku P, Leinonen M, Hassi J, Harju T.

J Asthma. 2008 Apr;45(3):237-42. doi: 10.1080/02770900701883790.

PMID:
18415833
33.

Size at birth, weight gain over the life course, and low-grade inflammation in young adulthood: northern Finland 1966 Birth Cohort study.

Tzoulaki I, Jarvelin MR, Hartikainen AL, Leinonen M, Pouta A, Paldanius M, Ruokonen A, Canoy D, Sovio U, Saikku P, Elliott P.

Eur Heart J. 2008 Apr;29(8):1049-56. doi: 10.1093/eurheartj/ehn105. Epub 2008 Apr 9.

PMID:
18403494
34.

Comparison of polymerase chain reaction methods, in situ hybridization, and enzyme immunoassay for detection of Chlamydia pneumoniae in atherosclerotic carotid plaques.

Lajunen T, Vikatmaa P, Ikonen T, Lepäntalo M, Lounatmaa K, Sormunen R, Rantala A, Leinonen M, Saikku P.

Diagn Microbiol Infect Dis. 2008 Jun;61(2):156-64. doi: 10.1016/j.diagmicrobio.2008.01.006. Epub 2008 Mar 4.

PMID:
18308498
35.

Susceptibility of human monocyte-macrophages to Chlamydia pneumoniae infection in vitro is highly variable and associated with levels of soluble CD14 and C. pneumoniae IgA and human HSP-IgG antibodies in serum.

Poikonen K, Lajunen T, Silvennoinen-Kassinen S, Paldanius M, Leinonen M, Saikku P.

Scand J Immunol. 2008 Mar;67(3):279-84. doi: 10.1111/j.1365-3083.2007.02061.x. Epub 2008 Jan 10.

36.

Acute Chlamydia pneumoniae infections in asthmatic and non-asthmatic military conscripts during a non-epidemic period.

Juvonen R, Bloigu A, Paldanius M, Peitso A, Silvennoinen-Kassinen S, Harju T, Leinonen M, Saikku P.

Clin Microbiol Infect. 2008 Mar;14(3):207-12. Epub 2007 Dec 5.

37.

Association of Chlamydia pneumoniae infection with HLA-B*35 in patients with coronary artery disease.

Palikhe A, Lokki ML, Saikku P, Leinonen M, Paldanius M, Seppänen M, Valtonen V, Nieminen MS, Sinisalo J.

Clin Vaccine Immunol. 2008 Jan;15(1):55-9. Epub 2007 Nov 7.

38.

Asthmatic persons are prone to the persistence of Chlamydia pneumoniae antibodies.

Paldanius M, Juvonen R, Leinonen M, Bloigu A, Silvennoinen-Kassinen S, Saikku P.

Diagn Microbiol Infect Dis. 2007 Oct;59(2):117-22. Epub 2007 Jun 15.

PMID:
17572038
39.

Effect of pravastatin treatment on Chlamydia pneumoniae infection, inflammation and serum lipids in NIH/S mice.

Tiirola T, Jauhiainen M, Erkkilä L, Bloigu A, Leinonen M, Haasio K, Laitinen K, Saikku P.

Int J Antimicrob Agents. 2007 Jun;29(6):741-2. Epub 2007 Mar 21. No abstract available.

PMID:
17369028
40.

Rapid genotyping of lipopolysaccharide-binding protein (LBP) C(1341)-->T (Leu(436)-->Phe) polymorphism by LightCycler real-time PCR.

Korhonen T, Grauling-Halama S, Halama N, Silvennoinen-Kassinen S, Leinonen M, Saikku P.

J Immunol Methods. 2006 Dec 20;317(1-2):171-4. Epub 2006 Nov 3.

PMID:
17101145
41.

Risk of cervical cancer associated with Chlamydia trachomatis antibodies by histology, HPV type and HPV cofactors.

Madeleine MM, Anttila T, Schwartz SM, Saikku P, Leinonen M, Carter JJ, Wurscher M, Johnson LG, Galloway DA, Daling JR.

Int J Cancer. 2007 Feb 1;120(3):650-5.

42.

Chlamydial lipopolysaccharide is present in serum during acute coronary syndrome and correlates with CRP levels.

Tiirola T, Sinisalo J, Nieminen MS, Silvennoinen-Kassinen S, Paldanius M, Saikku P, Jauhiainen M, Leinonen M.

Atherosclerosis. 2007 Oct;194(2):403-7. Epub 2006 Sep 15.

PMID:
16978631
43.

Increased prostanoid dependency of arterial relaxation in Chlamydia pneumoniae-infected mice.

Törmäkangas L, Ketonen J, Leinonen M, Saikku P, Paakkari I.

J Med Microbiol. 2006 Aug;55(Pt 8):1017-21.

PMID:
16849721
44.

Chlamydia pneumoniae antibody levels before coronary events in the Helsinki Heart Study as measured by different methods.

Paldanius M, Leinonen M, Virkkunen H, Tenkanen L, Sävykoski T, Mänttäri M, Saikku P.

Diagn Microbiol Infect Dis. 2006 Nov;56(3):233-9. Epub 2006 Jun 6.

PMID:
16757141
45.

Pathogenic bacteria and viruses in induced sputum or pharyngeal secretions of adults with stable asthma.

Harju TH, Leinonen M, Nokso-Koivisto J, Korhonen T, Räty R, He Q, Hovi T, Mertsola J, Bloigu A, Rytilä P, Saikku P.

Thorax. 2006 Jul;61(7):579-84. Epub 2006 Mar 3.

46.

Inhibitory effect of heparan sulfate-like glycosaminoglycans on the infectivity of Chlamydia pneumoniae in HL cells varies between strains.

Yan Y, Silvennoinen-Kassinen S, Leinonen M, Saikku P.

Microbes Infect. 2006 Mar;8(3):866-72. Epub 2006 Jan 17.

PMID:
16500132
47.

Prevalence and persistence of antibodies to herpes viruses, Chlamydia pneumoniae and Helicobacter pylori in Alaskan Eskimos: the GOCADAN Study.

Zhu J, Davidson M, Leinonen M, Saikku P, Gaydos CA, Canos DA, Gutman KA, Howard BV, Epstein SE; GOCADAN Study Investigators.

Clin Microbiol Infect. 2006 Feb;12(2):118-22.

48.

Inhibitory effect of dietary phenolic compounds on Chlamydia pneumoniae in cell cultures.

Alvesalo J, Vuorela H, Tammela P, Leinonen M, Saikku P, Vuorela P.

Biochem Pharmacol. 2006 Mar 14;71(6):735-41. Epub 2006 Jan 18.

PMID:
16414027
49.

Novel enzyme immunoassay utilizing lipopolysaccharide-binding protein as a capture molecule for the measurement of chlamydial lipopolysaccharide in serum.

Tiirola T, Jaakkola A, Bloigu A, Paldanius M, Sinisalo J, Nieminen MS, Silvennoinen-Kassinen S, Saikku P, Jauhiainen M, Leinonen M.

Diagn Microbiol Infect Dis. 2006 Jan;54(1):7-12. Epub 2005 Nov 14.

PMID:
16290027
50.

[Isn't chlamydia the cause of atherosclerosis?].

Saikku P, Leinonen M.

Duodecim. 2005;121(14):1572-4; author reply 1574. Finnish. No abstract available.

PMID:
16209322

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