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Items: 1 to 50 of 108

1.

Study of the Inhibitory Effects of Enteral Nutrition Formula on Indomethacin-Induced Gastric Lesions in Mice.

Yoshimi T, Yamagishi Y, Kanegawa I, Suda M, Saiki R, Tanaka KI, Goda H, Kudo T, Ito K.

Nutrients. 2019 Dec 14;11(12). pii: E3058. doi: 10.3390/nu11123058.

2.

Association of ghrelin dynamics with beta cell function in Japanese subjects with normal glucose tolerance.

Murai N, Saito N, Kodama E, Iida T, Mikura K, Imai H, Kaji M, Hashizume M, Kigawa Y, Koizumi G, Tadokoro R, Sugisawa C, Endo K, Iizaka T, Saiki R, Otsuka F, Shun I, Nagasaka S.

Clin Endocrinol (Oxf). 2019 Nov;91(5):616-623. doi: 10.1111/cen.14073. Epub 2019 Sep 11.

PMID:
31408197
3.

Continuous Hemodiafiltration for Pheochromocytoma Crisis with a Positive Outcome.

Koizumi G, Saiki R, Kurokawa I, Mikura K, Iida T, Murai N, Kaji M, Hashizume M, Kigawa Y, Endo K, Iizaka T, Otsuka F, Isobe T, Norose T, Ohike N, Sasaki J, Hayashi M, Sasaki H, Nagasaka S.

Intern Med. 2019 Nov 1;58(21):3113-3119. doi: 10.2169/internalmedicine.2991-19. Epub 2019 Jul 10.

4.

A Brønsted-Ligand-Based Iron Complex as a Molecular Switch with Five Accessible States.

Shiga T, Saiki R, Akiyama L, Kumai R, Natke D, Renz F, Cameron JM, Newton GN, Oshio H.

Angew Chem Int Ed Engl. 2019 Apr 16;58(17):5658-5662. doi: 10.1002/anie.201900909. Epub 2019 Mar 20.

PMID:
30753754
5.

Substituent dependence on the spin crossover behaviour of mononuclear Fe(ii) complexes with asymmetric tridentate ligands.

Saiki R, Miyamoto H, Sagayama H, Kumai R, Newton GN, Shiga T, Oshio H.

Dalton Trans. 2019 Mar 14;48(10):3231-3236. doi: 10.1039/c9dt00204a. Epub 2019 Feb 5.

PMID:
30720038
6.

Early pathology in venom-induced consumption coagulopathy by Rhabdophis tigrinus (Yamakagashi snake) envenomation.

Ichiki T, Kohda F, Hiramatsu T, Saiki R, Sakai A, Furue M.

Clin Toxicol (Phila). 2019 Jul;57(7):668-671. doi: 10.1080/15563650.2018.1540045. Epub 2019 Jan 28.

PMID:
30689439
7.

A case of pheochromocytoma with a marked decrease in catecholamine levels after rupture in which a good outcome was achieved by elective surgery.

Murai N, Azami T, Iida T, Mikura K, Imai H, Kaji M, Hashizume M, Kigawa Y, Koizumi G, Tadokoro R, Endo K, Iizaka T, Saiki R, Otsuka F, Norose T, Yamagishi M, Kurokawa I, Oike N, Sasaki H, Nagasaka S.

Endocr J. 2018 Nov 29;65(11):1093-1099. doi: 10.1507/endocrj.EJ18-0071. Epub 2018 Aug 4.

8.

Immune checkpoint inhibitors and radiosurgery for newly diagnosed melanoma brain metastases.

Robin TP, Breeze RE, Smith DE, Rusthoven CG, Lewis KD, Gonzalez R, Brill A, Saiki R, Stuhr K, Gaspar LE, Karam SD, Raben D, Kavanagh BD, Nath SK, Liu AK.

J Neurooncol. 2018 Oct;140(1):55-62. doi: 10.1007/s11060-018-2930-5. Epub 2018 Jun 16.

9.

Four-year Survival (and Counting) after Stereotactic Radiosurgery to Nearly 100 Brain Metastases: A Case Report.

Saiki R, Brill A, Breeze RE.

Cureus. 2018 Jan 23;10(1):e2103. doi: 10.7759/cureus.2103.

10.

Design, synthesis, and evaluation of polyamine-memantine hybrids as NMDA channel blockers.

Kumamoto T, Nakajima M, Uga R, Ihayazaka N, Kashihara H, Katakawa K, Ishikawa T, Saiki R, Nishimura K, Igarashi K.

Bioorg Med Chem. 2018 Feb 1;26(3):603-608. doi: 10.1016/j.bmc.2017.12.021. Epub 2017 Dec 16.

PMID:
29277306
11.

Time dependent transition of the levels of protein-conjugated acrolein (PC-Acro), IL-6 and CRP in plasma during stroke.

Yoshida M, Kato N, Uemura T, Mizoi M, Nakamura M, Saiki R, Hatano K, Sato K, Kakizaki S, Nakamura A, Ishii T, Terao T, Murayama Y, Kashiwagi K, Igarashi K.

eNeurologicalSci. 2017 Mar 30;7:18-24. doi: 10.1016/j.ensci.2017.03.005. eCollection 2017 Jun.

12.

Alcohol flushing is independently associated with lesser degree of carotid atherosclerosis in Japanese type 2 diabetic patients.

Murai N, Saiki R, Hashizume M, Kigawa Y, Koizumi G, Tadokoro R, Endo K, Iizaka T, Otsuka F, Izumizaki M, Nagasaka S.

Diabetol Int. 2017 Jul 28;9(1):68-74. doi: 10.1007/s13340-017-0332-0. eCollection 2018 Feb.

13.

Activation of MMP-9 activity by acrolein in saliva from patients with primary Sjögren's syndrome and its mechanism.

Uemura T, Suzuki T, Saiki R, Dohmae N, Ito S, Takahashi H, Toida T, Kashiwagi K, Igarashi K.

Int J Biochem Cell Biol. 2017 Jul;88:84-91. doi: 10.1016/j.biocel.2017.05.004. Epub 2017 May 5.

PMID:
28483671
14.

Oxalate-bridged heterometallic chains with monocationic dabco derivatives.

Sakurai T, Saiki R, Wei RJ, Newton GN, Shiga T, Oshio H.

Dalton Trans. 2016 Oct 18;45(41):16182-16189.

PMID:
27722616
15.

L-Arginine intervention at hyper-acute phase protects the prolonged MRI abnormality in MELAS.

Kitamura M, Yatsuga S, Abe T, Povalko N, Saiki R, Ushijima K, Yamashita Y, Koga Y.

J Neurol. 2016 Aug;263(8):1666-8. doi: 10.1007/s00415-016-8069-4. Epub 2016 Jun 22. No abstract available.

16.

Aggravation of brain infarction through an increase in acrolein production and a decrease in glutathione with aging.

Uemura T, Watanabe K, Ishibashi M, Saiki R, Kuni K, Nishimura K, Toida T, Kashiwagi K, Igarashi K.

Biochem Biophys Res Commun. 2016 Apr 29;473(2):630-5. doi: 10.1016/j.bbrc.2016.03.137. Epub 2016 Mar 30.

PMID:
27037020
17.

Toxic acrolein production due to Ca(2+) influx by the NMDA receptor during stroke.

Nakamura M, Uemura T, Saiki R, Sakamoto A, Park H, Nishimura K, Terui Y, Toida T, Kashiwagi K, Igarashi K.

Atherosclerosis. 2016 Jan;244:131-7. doi: 10.1016/j.atherosclerosis.2015.11.012. Epub 2015 Nov 14.

PMID:
26630182
18.

Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders.

Yatsuga S, Fujita Y, Ishii A, Fukumoto Y, Arahata H, Kakuma T, Kojima T, Ito M, Tanaka M, Saiki R, Koga Y.

Ann Neurol. 2015 Nov;78(5):814-23. doi: 10.1002/ana.24506. Epub 2015 Oct 14.

19.

Increase in acrolein-conjugated immunoglobulins in saliva from patients with primary Sjögren's syndrome.

Hirose T, Saiki R, Uemura T, Suzuki T, Dohmae N, Ito S, Takahashi H, Ishii I, Toida T, Kashiwagi K, Igarashi K.

Clin Chim Acta. 2015 Oct 23;450:184-9. doi: 10.1016/j.cca.2015.08.018. Epub 2015 Aug 21.

PMID:
26301996
20.

Spermidine and Ca(2+), but not Na(+), can permeate NMDA receptors consisting of GluN1 and GluN2A or GluN2B in the presence of Mg(2+).

Hirose T, Saiki R, Yoshizawa Y, Imamura M, Higashi K, Ishii I, Toida T, Williams K, Kashiwagi K, Igarashi K.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):1190-5. doi: 10.1016/j.bbrc.2015.06.081. Epub 2015 Jun 15.

PMID:
26086092
21.

High juvenile hormone titre and abdominal activation of JH signalling may induce reproduction of termite neotenics.

Saiki R, Gotoh H, Toga K, Miura T, Maekawa K.

Insect Mol Biol. 2015 Aug;24(4):432-41. doi: 10.1111/imb.12169. Epub 2015 Apr 3.

PMID:
25847681
22.

Polyphenol extract from Phellinus igniarius protects against acrolein toxicity in vitro and provides protection in a mouse stroke model.

Suabjakyong P, Saiki R, Van Griensven LJ, Higashi K, Nishimura K, Igarashi K, Toida T.

PLoS One. 2015 Mar 26;10(3):e0122733. doi: 10.1371/journal.pone.0122733. eCollection 2015.

23.

Distinguishing mild cognitive impairment from Alzheimer's disease with acrolein metabolites and creatinine in urine.

Yoshida M, Higashi K, Kuni K, Mizoi M, Saiki R, Nakamura M, Waragai M, Uemura K, Toida T, Kashiwagi K, Igarashi K.

Clin Chim Acta. 2015 Feb 20;441:115-21. doi: 10.1016/j.cca.2014.12.023. Epub 2014 Dec 24.

PMID:
25542982
24.

Reproductive Soldier-like Individuals Induced by Juvenile Hormone Analog Treatment in Zootermopsis nevadensis (Isoptera, Archotermopsidae).

Saiki R, Yaguchi H, Hashimoto Y, Kawamura S, Maekawa K.

Zoolog Sci. 2014 Sep;31(9):573-81. doi: 10.2108/zs140083.

PMID:
25186928
25.

Intracolonial genetic variation affects reproductive skew and colony productivity during colony foundation in a parthenogenetic termite.

Miyazaki S, Yoshimura M, Saiki R, Hayashi Y, Kitade O, Tsuji K, Maekawa K.

BMC Evol Biol. 2014 Aug 14;14:177. doi: 10.1186/s12862-014-0177-0.

26.

Identification of functional amino acid residues involved in polyamine and agmatine transport by human organic cation transporter 2.

Higashi K, Imamura M, Fudo S, Uemura T, Saiki R, Hoshino T, Toida T, Kashiwagi K, Igarashi K.

PLoS One. 2014 Jul 14;9(7):e102234. doi: 10.1371/journal.pone.0102234. eCollection 2014.

27.

Distinction between mild cognitive impairment and Alzheimer's disease by CSF amyloid β40 and β42, and protein-conjugated acrolein.

Mizoi M, Yoshida M, Saiki R, Waragai M, Uemura K, Akatsu H, Kashiwagi K, Igarashi K.

Clin Chim Acta. 2014 Mar 20;430:150-5. doi: 10.1016/j.cca.2014.01.007. Epub 2014 Feb 6.

PMID:
24508996
28.

Construction and characterization of normalized cDNA libraries by 454 pyrosequencing and estimation of DNA methylation levels in three distantly related termite species.

Hayashi Y, Shigenobu S, Watanabe D, Toga K, Saiki R, Shimada K, Bourguignon T, Lo N, Hojo M, Maekawa K, Miura T.

PLoS One. 2013 Sep 30;8(9):e76678. doi: 10.1371/journal.pone.0076678. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/b1ec420f-0227-4362-bb96-638a352f86d4.

29.

High Laccase2 expression is likely involved in the formation of specific cuticular structures during soldier differentiation of the termite Reticulitermes speratus.

Masuoka Y, Miyazaki S, Saiki R, Tsuchida T, Maekawa K.

Arthropod Struct Dev. 2013 Nov;42(6):469-475. doi: 10.1016/j.asd.2013.08.003. Epub 2013 Sep 25.

PMID:
24076334
30.

Acrolein stimulates the synthesis of IL-6 and C-reactive protein (CRP) in thrombosis model mice and cultured cells.

Saiki R, Hayashi D, Ikuo Y, Nishimura K, Ishii I, Kobayashi K, Chiba K, Toida T, Kashiwagi K, Igarashi K.

J Neurochem. 2013 Dec;127(5):652-9. doi: 10.1111/jnc.12336. Epub 2013 Jul 1.

31.

In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers.

Saiki R, Yoshizawa Y, Minarini A, Milelli A, Marchetti C, Tumiatti V, Toida T, Kashiwagi K, Igarashi K.

Bioorg Med Chem Lett. 2013 Jul 1;23(13):3901-4. doi: 10.1016/j.bmcl.2013.04.063. Epub 2013 May 2.

PMID:
23692871
32.

Hox Gene Deformed is likely involved in mandibular regression during presoldier differentiation in the nasute termite Nasutitermes takasagoensis.

Toga K, Saiki R, Maekawa K.

J Exp Zool B Mol Dev Evol. 2013 Sep;320(6):385-92. doi: 10.1002/jez.b.22512. Epub 2013 May 15.

PMID:
23677571
33.

Genetic diversity and geographical distribution of indigenous soybean-nodulating bradyrhizobia in the United States.

Shiro S, Matsuura S, Saiki R, Sigua GC, Yamamoto A, Umehara Y, Hayashi M, Saeki Y.

Appl Environ Microbiol. 2013 Jun;79(12):3610-8. doi: 10.1128/AEM.00236-13. Epub 2013 Apr 5.

34.

Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle.

Yamashita T, Nishimura K, Saiki R, Okudaira H, Tome M, Higashi K, Nakamura M, Terui Y, Fujiwara K, Kashiwagi K, Igarashi K.

Int J Biochem Cell Biol. 2013 Jun;45(6):1042-50. doi: 10.1016/j.biocel.2013.02.021. Epub 2013 Mar 14.

PMID:
23500523
35.

Acrolein-conjugated low-density lipoprotein induces macrophage foam cell formation.

Watanabe K, Nakazato Y, Saiki R, Igarashi K, Kitada M, Ishii I.

Atherosclerosis. 2013 Mar;227(1):51-7. doi: 10.1016/j.atherosclerosis.2012.12.020. Epub 2012 Dec 25.

PMID:
23305793
36.

A conserved START domain coenzyme Q-binding polypeptide is required for efficient Q biosynthesis, respiratory electron transport, and antioxidant function in Saccharomyces cerevisiae.

Allan CM, Hill S, Morvaridi S, Saiki R, Johnson JS, Liau WS, Hirano K, Kawashima T, Ji Z, Loo JA, Shepherd JN, Clarke CF.

Biochim Biophys Acta. 2013 Apr;1831(4):776-791. doi: 10.1016/j.bbalip.2012.12.007. Epub 2012 Dec 25.

37.

Inactivation of GAPDH as one mechanism of acrolein toxicity.

Nakamura M, Tomitori H, Suzuki T, Sakamoto A, Terui Y, Saiki R, Dohmae N, Igarashi K, Kashiwagi K.

Biochem Biophys Res Commun. 2013 Jan 25;430(4):1265-71. doi: 10.1016/j.bbrc.2012.12.057. Epub 2012 Dec 20.

PMID:
23261472
38.

Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli.

Gomez F, Monsalve GC, Tse V, Saiki R, Weng E, Lee L, Srinivasan C, Frand AR, Clarke CF.

BMC Microbiol. 2012 Dec 20;12:300. doi: 10.1186/1471-2180-12-300.

39.

Increased protein-conjugated acrolein and amyloid-β40/42 ratio in plasma of patients with mild cognitive impairment and Alzheimer's disease.

Waragai M, Yoshida M, Mizoi M, Saiki R, Kashiwagi K, Takagi K, Arai H, Tashiro J, Hashimoto M, Iwai N, Uemura K, Igarashi K.

J Alzheimers Dis. 2012;32(1):33-41.

PMID:
22751175
40.

Structural changes of regulatory domain heterodimer of N-methyl-D-aspartate receptor subunits GluN1 and GluN2B through the binding of spermine and ifenprodil.

Tomitori H, Suganami A, Saiki R, Mizuno S, Yoshizawa Y, Masuko T, Tamura Y, Nishimura K, Toida T, Williams K, Kashiwagi K, Igarashi K.

J Pharmacol Exp Ther. 2012 Oct;343(1):82-90. doi: 10.1124/jpet.112.192286. Epub 2012 Jun 28.

41.

Restoring de novo coenzyme Q biosynthesis in Caenorhabditis elegans coq-3 mutants yields profound rescue compared to exogenous coenzyme Q supplementation.

Gomez F, Saiki R, Chin R, Srinivasan C, Clarke CF.

Gene. 2012 Sep 10;506(1):106-16. doi: 10.1016/j.gene.2012.06.023. Epub 2012 Jun 23.

42.

AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells.

Zhang D, Zhao T, Ang HS, Chong P, Saiki R, Igarashi K, Yang H, Vardy LA.

Genes Dev. 2012 Mar 1;26(5):461-73. doi: 10.1101/gad.182998.111.

43.

A case of painless thyroiditis in a very early stage of pregnancy.

Sato S, Endo K, Iizaka T, Saiki R, Iwaku K, Sato S, Takahashi Y, Otsuka F, Taniyama M.

Intern Med. 2012;51(5):475-7. Epub 2012 Mar 1.

44.

Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite.

Yoshida M, Mikami T, Higashi K, Saiki R, Mizoi M, Fukuda K, Nakamura T, Ishii I, Nishimura K, Toida T, Tomitori H, Kashiwagi K, Igarashi K.

Clin Chim Acta. 2012 Apr 11;413(7-8):753-9. doi: 10.1016/j.cca.2012.01.020. Epub 2012 Jan 26.

PMID:
22293277
45.

Brain infarction correlates more closely with acrolein than with reactive oxygen species.

Saiki R, Park H, Ishii I, Yoshida M, Nishimura K, Toida T, Tatsukawa H, Kojima S, Ikeguchi Y, Pegg AE, Kashiwagi K, Igarashi K.

Biochem Biophys Res Commun. 2011 Jan 28;404(4):1044-9. doi: 10.1016/j.bbrc.2010.12.107. Epub 2010 Dec 25.

PMID:
21187074
46.

Relationship between metabolic disorders and relative risk values of brain infarction estimated by protein-conjugated acrolein, IL-6 and CRP together with age.

Yoshida M, Mizoi M, Saiki R, Kobayashi E, Saeki N, Wakui K, Kusaka T, Takizawa H, Kashiwado K, Suzuki N, Fukuda K, Nakamura T, Watanabe S, Tada K, Tomitori H, Kashiwagi K, Igarashi K.

Clin Chim Acta. 2011 Jan 30;412(3-4):339-42. doi: 10.1016/j.cca.2010.11.003. Epub 2010 Nov 8.

PMID:
21070758
47.

Current and evolving management of traumatic brain injury.

Saiki RL.

Crit Care Nurs Clin North Am. 2009 Dec;21(4):549-59. doi: 10.1016/j.ccell.2009.07.009.

PMID:
19951770
48.

Intense correlation between brain infarction and protein-conjugated acrolein.

Saiki R, Nishimura K, Ishii I, Omura T, Okuyama S, Kashiwagi K, Igarashi K.

Stroke. 2009 Oct;40(10):3356-61. doi: 10.1161/STROKEAHA.109.553248. Epub 2009 Aug 6.

PMID:
19661476
49.

Comparison of a coq7 deletion mutant with other respiration-defective mutants in fission yeast.

Miki R, Saiki R, Ozoe Y, Kawamukai M.

FEBS J. 2008 Nov;275(21):5309-24. doi: 10.1111/j.1742-4658.2008.06661.x. Epub 2008 Sep 19.

50.

Coenzyme Q10 supplementation rescues renal disease in Pdss2kd/kd mice with mutations in prenyl diphosphate synthase subunit 2.

Saiki R, Lunceford AL, Shi Y, Marbois B, King R, Pachuski J, Kawamukai M, Gasser DL, Clarke CF.

Am J Physiol Renal Physiol. 2008 Nov;295(5):F1535-44. doi: 10.1152/ajprenal.90445.2008. Epub 2008 Sep 10.

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